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公开(公告)号：US20120107439A1
公开(公告)日：2012-05-03
申请号：US13209020
申请日：2011-08-12
申请人： Upma Sharma , Irina Gitlin , Gregory T. Zugates , Adam Rago , Parisa Zamiri , Rany Busold , Robert J. Caulkins , Toby Freyman , Quynh P. Pham , Changcheng You , Jeffrey D. Carbeck
发明人： Upma Sharma , Irina Gitlin , Gregory T. Zugates , Adam Rago , Parisa Zamiri , Rany Busold , Robert J. Caulkins , Toby Freyman , Quynh P. Pham , Changcheng You , Jeffrey D. Carbeck
IPC分类号： B29C44/04
CPC分类号： A61L31/06 , A61B17/12031 , A61B17/12163 , A61B17/12186 , A61B2017/12004 , A61J1/2093 , A61L27/18 , A61L27/56 , A61L27/58 , A61L31/141 , A61L31/146 , A61L31/148 , A61L2400/04 , A61L2400/06 , A61L2400/18 , A61M37/00 , C08L63/00 , C08L67/04
摘要： Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
摘要翻译： 通常描述与聚合物泡沫有关的系统和方法。 一些实施方案涉及用于制备聚合物泡沫的组合物和方法，以及使用聚合物泡沫体的方法。 聚合物泡沫可以施加到体腔并且与例如组织，损伤的组织，内部器官等接触。在一些实施方案中，聚合物泡沫可以在体腔内形成（即，原位泡沫形成 ）。 此外，发泡聚合物可能能够在体腔的内表面上施加压力，并且能够防止或限制体液（例如血液等）的移动。
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公开(公告)号：US09173817B2
公开(公告)日：2015-11-03
申请号：US13209020
申请日：2011-08-12
申请人： Upma Sharma , Irina Gitlin , Gregory T. Zugates , Adam Rago , Parisa Zamiri , Rany Busold , Toby Freyman , Robert J. Caulkins , Quynh P. Pham , Changcheng You , Jeffrey D. Carbeck
发明人： Upma Sharma , Irina Gitlin , Gregory T. Zugates , Adam Rago , Parisa Zamiri , Rany Busold , Toby Freyman , Robert J. Caulkins , Quynh P. Pham , Changcheng You , Jeffrey D. Carbeck
CPC分类号： A61L31/06 , A61B17/12031 , A61B17/12163 , A61B17/12186 , A61B2017/12004 , A61J1/2093 , A61L27/18 , A61L27/56 , A61L27/58 , A61L31/141 , A61L31/146 , A61L31/148 , A61L2400/04 , A61L2400/06 , A61L2400/18 , A61M37/00 , C08L63/00 , C08L67/04
摘要： Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
摘要翻译： 通常描述与聚合物泡沫有关的系统和方法。 一些实施方案涉及用于制备聚合物泡沫的组合物和方法，以及使用聚合物泡沫体的方法。 聚合物泡沫可以施加到体腔并且与例如组织，损伤的组织，内部器官等接触。在一些实施方案中，聚合物泡沫可以在体腔内形成（即，原位泡沫形成 ）。 此外，发泡聚合物可能能够在体腔的内表面上施加压力，并且能够防止或限制体液（例如血液等）的移动。
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公开(公告)号：US09700656B2
公开(公告)日：2017-07-11
申请号：US14492393
申请日：2014-09-22
申请人： Upma Sharma , Irina Gitlin , Gregory T. Zugates , Adam Rago , Parisa Zamiri , Rany Busold , Toby Freyman , Robert J. Caulkins , Quynh P. Pham , Changchen You , Jeffrey D. Carbeck
发明人： Upma Sharma , Irina Gitlin , Gregory T. Zugates , Adam Rago , Parisa Zamiri , Rany Busold , Toby Freyman , Robert J. Caulkins , Quynh P. Pham , Changchen You , Jeffrey D. Carbeck
IPC分类号： A61F2/02 , A61L31/06 , A61J1/20 , A61L27/18 , A61L27/56 , A61L27/58 , A61L31/14 , A61M37/00 , A61B17/12
CPC分类号： A61L31/06 , A61B17/12031 , A61B17/12163 , A61B17/12186 , A61B2017/12004 , A61J1/2093 , A61L27/18 , A61L27/56 , A61L27/58 , A61L31/141 , A61L31/146 , A61L31/148 , A61L2400/04 , A61L2400/06 , A61L2400/18 , A61M37/00 , C08L63/00 , C08L67/04
摘要： Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
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公开(公告)号：US20150224235A1
公开(公告)日：2015-08-13
申请号：US14492393
申请日：2014-09-22
申请人： Upma Sharma , Irina Gitlin , Gregory T. Zugates , Adam Rago , Parisa Zamiri , Rany Busold , Toby Freyman , Robert J. Caulkins , Quynh P. Pham , Changchen You , Jeffrey D. Carbeck
发明人： Upma Sharma , Irina Gitlin , Gregory T. Zugates , Adam Rago , Parisa Zamiri , Rany Busold , Toby Freyman , Robert J. Caulkins , Quynh P. Pham , Changchen You , Jeffrey D. Carbeck
CPC分类号： A61L31/06 , A61B17/12031 , A61B17/12163 , A61B17/12186 , A61B2017/12004 , A61J1/2093 , A61L27/18 , A61L27/56 , A61L27/58 , A61L31/141 , A61L31/146 , A61L31/148 , A61L2400/04 , A61L2400/06 , A61L2400/18 , A61M37/00 , C08L63/00 , C08L67/04
摘要： Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
摘要翻译： 通常描述与聚合物泡沫有关的系统和方法。 一些实施方案涉及用于制备聚合物泡沫的组合物和方法，以及使用聚合物泡沫体的方法。 聚合物泡沫可以施加到体腔并且与例如组织，损伤的组织，内部器官等接触。在一些实施方案中，聚合物泡沫可以在体腔内形成（即，原位泡沫形成 ）。 此外，发泡聚合物可能能够在体腔的内表面上施加压力，并且能够防止或限制体液（例如血液等）的移动。
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公开(公告)号：US20160279302A1
公开(公告)日：2016-09-29
申请号：US14928857
申请日：2015-10-30
申请人： Upma Sharma , Irina Gitlin , Gregory T. Zugates , Adam Rago , Parisa Zamiri , Ray Busold , Robert J. Caulkins , Toby Freyman , Quynh Pham , Changchen You , Jeffrey Carbeck
发明人： Upma Sharma , Irina Gitlin , Gregory T. Zugates , Adam Rago , Parisa Zamiri , Ray Busold , Robert J. Caulkins , Toby Freyman , Quynh Pham , Changchen You , Jeffrey Carbeck
CPC分类号： A61L31/06 , A61B17/12031 , A61B17/12163 , A61B17/12186 , A61B2017/12004 , A61J1/2093 , A61L27/18 , A61L27/56 , A61L27/58 , A61L31/141 , A61L31/146 , A61L31/148 , A61L2400/04 , A61L2400/06 , A61L2400/18 , A61M37/00 , C08L63/00 , C08L67/04
摘要： Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).
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公开(公告)号：US09623143B2
公开(公告)日：2017-04-18
申请号：US14215988
申请日：2014-03-17
申请人： Gregory T. Zugates , Adam Rago , Toby Freyman , Upma Sharma , Rany Busold , John Caulkins , Parisa Zamiri , Jennifer Mortensen , Meghan McGill , Daniel K. Bonner
发明人： Gregory T. Zugates , Adam Rago , Toby Freyman , Upma Sharma , Rany Busold , John Caulkins , Parisa Zamiri , Jennifer Mortensen , Meghan McGill , Daniel K. Bonner
CPC分类号： A61L24/0015 , A61L24/0036 , A61L24/046 , A61L27/14 , A61L27/56 , A61L31/04 , A61L31/146 , A61L2300/418 , A61L2400/04 , A61L2430/22 , C08L75/04
摘要： The present invention relates generally to systems and methods and systems for generating polymer foams within body cavities to locate and/or control bleeding. The present invention further relates to methods and systems for generating polymer foams within non-compressible wounds to control or stop bleeding. The present invention further relates to the use of foams and gels for medical and cosmetic purposes.
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公开(公告)号：US20140316367A1
公开(公告)日：2014-10-23
申请号：US14215988
申请日：2014-03-17
申请人： Gregory T. Zugates , Adam Rago , Toby Freyman , Upma Sharma , Rany Busold , John Caulkins , Parisa Zamiri , Jennifer Mortensen , Meghan McGill , Daniel K. Bonner
发明人： Gregory T. Zugates , Adam Rago , Toby Freyman , Upma Sharma , Rany Busold , John Caulkins , Parisa Zamiri , Jennifer Mortensen , Meghan McGill , Daniel K. Bonner
CPC分类号： A61L24/0015 , A61L24/0036 , A61L24/046 , A61L27/14 , A61L27/56 , A61L31/04 , A61L31/146 , A61L2300/418 , A61L2400/04 , A61L2430/22 , C08L75/04
摘要： The present invention relates generally to systems and methods and systems for generating polymer foams within body cavities to locate and/or control bleeding. The present invention further relates to methods and systems for generating polymer foams within non-compressible wounds to control or stop bleeding. The present invention further relates to the use of foams and gels for medical and cosmetic purposes.
摘要翻译： 本发明一般涉及用于在体腔内产生聚合物泡沫以定位和/或控制出血的系统和方法和系统。 本发明还涉及用于在不可压缩伤口内产生聚合物泡沫以控制或止血的方法和系统。 本发明还涉及泡沫和凝胶用于医疗和化妆用途的用途。
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8.发明申请公开(公告)号：US20160271293A1
公开(公告)日：2016-09-22
申请号：US14660790
申请日：2015-03-17
申请人： Gregory T. ZUGATES , Adam Rago , Toby Freyman , Upma Sharma , Rany Busold , John Caulkins , Parisa Zamiri , Jennifer Mortensen , David King
发明人： Gregory T. ZUGATES , Adam Rago , Toby Freyman , Upma Sharma , Rany Busold , John Caulkins , Parisa Zamiri , Jennifer Mortensen , David King
CPC分类号： A61B17/0057 , A61B17/12181 , A61B17/12186 , A61B17/12195 , A61B2017/00654 , A61L26/0014 , A61L26/008 , A61L2400/04
摘要： Systems and methods for the treatment of pelvic and junctional hemorrhage are provided, which utilize in situ forming polymer gels and foams to apply pressure to sites of hemorrhage due to penetrating or blunt injury, among other things.
摘要翻译： 提供了用于治疗盆腔和连接出血的系统和方法，其利用原位形成聚合物凝胶和泡沫来施加压力到由于穿透性或钝性损伤引起的出血部位等。
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公开(公告)号：US08993831B2
公开(公告)日：2015-03-31
申请号：US13536557
申请日：2012-06-28
申请人： Upma Sharma , Irina Gitlin , Parisa Zamiri , Toby Freyman , Rany Busold , Lee Core , Janet Chie Komatsu , Jennifer Mortensen
发明人： Upma Sharma , Irina Gitlin , Parisa Zamiri , Toby Freyman , Rany Busold , Lee Core , Janet Chie Komatsu , Jennifer Mortensen
IPC分类号： A61F13/53 , A61K47/34 , A61P7/04 , A61K9/00 , A61L24/00 , A61L24/04 , A61L27/14 , A61L27/56 , A61L31/04 , A61L31/14
CPC分类号： A61L24/0015 , A61L24/0036 , A61L24/046 , A61L27/14 , A61L27/56 , A61L31/04 , A61L31/146 , A61L2300/418 , A61L2400/04 , A61L2430/22 , C08L75/04
摘要： Medical implants and methods useful in treating postpartum hemorrhage are disclosed. The implants, in some embodiments, comprise polyurethane foams having advantageous mechanical and other properties selected to promote hemostasis when brought in contact with an inner wall of a uterus. Methods of making and deploying such implants are also disclosed.
摘要翻译： 公开了用于治疗产后出血的医疗植入物和方法。 在一些实施方案中，植入物包含具有有利的机械和其它性质的聚氨酯泡沫，当与子宫的内壁接触时，其被选择用于促进止血。 还公开了制造和部署这种植入物的方法。
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公开(公告)号：US20130110066A1
公开(公告)日：2013-05-02
申请号：US13536557
申请日：2012-06-28
申请人： Upma Sharma , Irina Gitlin , Parisa Zamiri , Toby Freyman , Rany Busold , Lee Core , Janet Chie Komatsu , Jennifer Mortensen
发明人： Upma Sharma , Irina Gitlin , Parisa Zamiri , Toby Freyman , Rany Busold , Lee Core , Janet Chie Komatsu , Jennifer Mortensen
CPC分类号： A61L24/0015 , A61L24/0036 , A61L24/046 , A61L27/14 , A61L27/56 , A61L31/04 , A61L31/146 , A61L2300/418 , A61L2400/04 , A61L2430/22 , C08L75/04
摘要： Medical implants and methods useful in treating postpartum hemorrhage are disclosed. The implants, in some embodiments, comprise polyurethane foams having advantageous mechanical and other properties selected to promote hemostasis when brought in contact with an inner wall of a uterus. Methods of making and deploying such implants are also disclosed.
摘要翻译： 公开了用于治疗产后出血的医疗植入物和方法。 在一些实施方案中，植入物包含具有有利的机械和其他性质的聚氨酯泡沫，当与子宫的内壁接触时，其被选择用于促进止血。 还公开了制造和部署这种植入物的方法。
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