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公开(公告)号：US20190008933A1
公开(公告)日：2019-01-10
申请号：US16137049
申请日：2018-09-20
摘要： The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
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公开(公告)号：US11697825B2
公开(公告)日：2023-07-11
申请号：US15535389
申请日：2015-12-11
发明人： James McLaughlin , Robert Kotin
IPC分类号： C12N15/864 , C12N15/35 , C12N7/00 , C07K14/015 , C12N15/09 , C12N15/861 , C07K14/005 , C12N15/86 , C12N7/02
CPC分类号： C12N15/861 , C07K14/005 , C12N7/00 , C12N7/02 , C12N15/86 , C12N15/864 , C12N2710/14144 , C12N2750/14122 , C12N2750/14143 , C12N2750/14151
摘要： The present invention is directed to viral vectors and methods of their production and use.
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公开(公告)号：US20210338786A1
公开(公告)日：2021-11-04
申请号：US17306376
申请日：2021-05-03
摘要： The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
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公开(公告)号：US20170362608A1
公开(公告)日：2017-12-21
申请号：US15535389
申请日：2015-12-11
发明人： James McLaughlin , Robert Kotin
IPC分类号： C12N15/861 , C12N7/02 , C12N15/864
CPC分类号： C12N15/861 , C07K14/005 , C12N7/00 , C12N7/02 , C12N15/86 , C12N15/864 , C12N2710/14144 , C12N2750/14122 , C12N2750/14143 , C12N2750/14151
摘要： The present invention is directed to viral vectors and methods of their production and use.
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公开(公告)号：US11975056B2
公开(公告)日：2024-05-07
申请号：US17306376
申请日：2021-05-03
CPC分类号： A61K38/51 , A61K35/76 , A61K48/005 , A61P25/14 , C12N7/00 , C12N9/88 , C12N15/86 , C12Y401/01028 , C12N2750/14121 , C12N2750/14143 , C12N2800/22 , C12N2830/42 , C12N2830/50
摘要： The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
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公开(公告)号：US10335466B2
公开(公告)日：2019-07-02
申请号：US15524986
申请日：2015-11-05
IPC分类号： A61K35/76 , A61P25/14 , A61P25/16 , C12N15/86 , C12N9/00 , C12N9/88 , A61K38/51 , A61K48/00 , C12N7/00
摘要： The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
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公开(公告)号：US20190008931A1
公开(公告)日：2019-01-10
申请号：US16136926
申请日：2018-09-20
摘要： The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
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公开(公告)号：US20190000940A1
公开(公告)日：2019-01-03
申请号：US15749019
申请日：2016-07-29
摘要： The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment, prophylaxis, palliation or amelioration of diseases, conditions and/or symptoms resulting from AADC deficiency and related inborn errors of neurotransmitter metabolism.
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公开(公告)号：US20170333538A1
公开(公告)日：2017-11-23
申请号：US15524986
申请日：2015-11-05
CPC分类号： A61K38/51 , A61K35/76 , A61K48/005 , A61P25/14 , C12N7/00 , C12N9/88 , C12N15/86 , C12N2750/14121 , C12N2750/14143 , C12N2800/22 , C12N2830/42 , C12N2830/50 , C12Y401/01028
摘要： The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
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公开(公告)号：US11027000B2
公开(公告)日：2021-06-08
申请号：US16540375
申请日：2019-08-14
摘要： The disclosure relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides encoding AADC for the treatment of Parkinson's Disease.
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