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公开(公告)号：US08753650B2
公开(公告)日：2014-06-17
申请号：US13253018
申请日：2011-10-04
申请人： Vega Masignani , Marirosa Mora , Maria Scarselli
发明人： Vega Masignani , Marirosa Mora , Maria Scarselli
IPC分类号： A61K39/085 , C07K14/31
CPC分类号： A61K39/085 , A61K2039/70 , C07K14/31
摘要： The invention provides proteins from Staphylococcus aureus including amino acid sequences and the corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies and also as targets for antibiotics.
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公开(公告)号：US08398996B2
公开(公告)日：2013-03-19
申请号：US12460422
申请日：2009-07-17
申请人： Vega Masignani , Marirosa Mora , Maria Scarselli
发明人： Vega Masignani , Marirosa Mora , Maria Scarselli
IPC分类号： A61K39/085 , C07K14/31
CPC分类号： A61K39/085 , A61K2039/70 , C07K14/31
摘要： The invention provides proteins from Staphylococcus aureus including amino acid sequences and the corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies and also as targets for antibiotics.
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公开(公告)号：US20120135024A1
公开(公告)日：2012-05-31
申请号：US13070448
申请日：2011-03-23
申请人： Claire FRASER , Cesira Galeotti , Guido Grandi , Erin Hickey , Vega Masignani , Marirosa Mora , Jeremy Petersen , Mariagrazia Pizza , Rino Rappuoli , Giulio Ratti , Vincenzo Scarlato , Maria Scarselli , Herve Tettelin , J. Craig Venter
发明人： Claire FRASER , Cesira Galeotti , Guido Grandi , Erin Hickey , Vega Masignani , Marirosa Mora , Jeremy Petersen , Mariagrazia Pizza , Rino Rappuoli , Giulio Ratti , Vincenzo Scarlato , Maria Scarselli , Herve Tettelin , J. Craig Venter
CPC分类号： C07K14/22 , A61K38/00 , A61K39/00 , A61K39/095 , A61K2039/55505 , Y10S530/806 , Y10S530/825
摘要： The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.
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公开(公告)号：US20090232820A1
公开(公告)日：2009-09-17
申请号：US12013047
申请日：2008-01-11
申请人： Claire FRASER , Cesira Galeotti , Guido Grandi , Erin Hickey , Vega Masignani , Marirosa Mora , Jeremy Petersen , Mariagrazia Pizza , Rino Rappuoli , Giulio Ratti , Vincenzo Scarlato , Maria Scarselli , Herve Tettelin , J. Craig Venter
发明人： Claire FRASER , Cesira Galeotti , Guido Grandi , Erin Hickey , Vega Masignani , Marirosa Mora , Jeremy Petersen , Mariagrazia Pizza , Rino Rappuoli , Giulio Ratti , Vincenzo Scarlato , Maria Scarselli , Herve Tettelin , J. Craig Venter
IPC分类号： A61K39/395 , C07K7/06 , C07K7/08 , C07K14/00 , A61K38/08 , A61K38/10 , A61K38/16 , C07K16/00 , C07H21/04
CPC分类号： C07K14/22 , A61K38/00 , A61K39/00 , A61K39/095 , A61K2039/55505 , Y10S530/806 , Y10S530/825
摘要： The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.
摘要翻译： 本发明提供脑膜炎奈瑟氏球菌的蛋白质，包括氨基酸序列和相应的核苷酸序列。 蛋白质被预测为用于疫苗和/或诊断的有用的抗原。
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公开(公告)号：US09139621B2
公开(公告)日：2015-09-22
申请号：US13070448
申请日：2011-03-23
申请人： Claire Fraser , Cesira Galeotti , Guido Grandi , Erin Hickey , Vega Masignani , Marirosa Mora , Jeremy Petersen , Mariagrazia Pizza , Rino Rappuoli , Giulio Ratti , Vincenzo Scarlato , Maria Scarselli , Herve Tettelin , J. Craig Venter
发明人： Claire Fraser , Cesira Galeotti , Guido Grandi , Erin Hickey , Vega Masignani , Marirosa Mora , Jeremy Petersen , Mariagrazia Pizza , Rino Rappuoli , Giulio Ratti , Vincenzo Scarlato , Maria Scarselli , Herve Tettelin , J. Craig Venter
IPC分类号： C07K14/22 , A61K39/095 , A61K39/00 , A61K38/00
CPC分类号： C07K14/22 , A61K38/00 , A61K39/00 , A61K39/095 , A61K2039/55505 , Y10S530/806 , Y10S530/825
摘要： The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.
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公开(公告)号：US08524251B2
公开(公告)日：2013-09-03
申请号：US13359471
申请日：2012-01-26
申请人： Claire Fraser , Cesira Galeotti , Guido Grandi , Erin Hickey , Vega Masignani , Marirosa Mora , Jeremy Petersen , Mariagrazia Pizza , Rino Rappuoli , Giulio Ratti , Vincenzo Scarlato , Maria Scarselli , Herve Tettelin , J. Craig Venter
发明人： Claire Fraser , Cesira Galeotti , Guido Grandi , Erin Hickey , Vega Masignani , Marirosa Mora , Jeremy Petersen , Mariagrazia Pizza , Rino Rappuoli , Giulio Ratti , Vincenzo Scarlato , Maria Scarselli , Herve Tettelin , J. Craig Venter
IPC分类号： A61K39/095 , A61K39/02 , A61K38/00 , C07K1/00
CPC分类号： C07K14/22 , A61K38/00 , A61K39/00 , A61K39/095 , A61K2039/55505 , Y10S530/806 , Y10S530/825
摘要： The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.
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公开(公告)号：US08287884B2
公开(公告)日：2012-10-16
申请号：US12573929
申请日：2009-10-06
申请人： Vega Masignani , Marirosa Mora , Maria Scarselli
发明人： Vega Masignani , Marirosa Mora , Maria Scarselli
IPC分类号： A61K39/085 , C07K14/31 , C07H21/04
CPC分类号： A61K39/085 , A61K2039/70 , C07K14/31
摘要： The invention provides proteins from Staphylococcus aureus, including amino acid sequences and corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies, and as targets for antibiotics.
摘要翻译： 本发明提供了来自金黄色葡萄球菌的蛋白质，包括氨基酸序列和相应的核苷酸序列。 这些蛋白质可用于疫苗，免疫原性组合物，诊断，酶学研究和抗生素靶标。
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公开(公告)号：US20120052084A1
公开(公告)日：2012-03-01
申请号：US13292977
申请日：2011-11-09
申请人： Vega Masignani , Marirosa Mora , Maria Scarselli
发明人： Vega Masignani , Marirosa Mora , Maria Scarselli
IPC分类号： A61K39/085 , A61K39/29 , A61K39/145 , A61K39/09 , A61P31/16 , A61K39/095 , A61P31/04 , A61P37/04 , A61P31/14 , A61P31/20 , C07K14/31 , A61K39/02
CPC分类号： A61K39/085 , A61K2039/70 , C07K14/31
摘要： The invention provides proteins from Staphylococcus aureus including amino acid sequences and the corresponding nucleotide sequences. The proteins are useful for vaccines, immunogenic compositions, diagnostics, enzymatic studies and also as targets for antibiotics.
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公开(公告)号：US07618636B1
公开(公告)日：2009-11-17
申请号：US10031289
申请日：2000-07-13
CPC分类号： C07K14/22 , A61K39/00 , A61K2039/505 , A61K2039/53 , Y10S530/825
摘要： WO99/36544 discloses a large number of proteins from Neisseria Meningitidis. The present invention relates to fragments of those proteins which comprise at least one antigenic determinant. Homologous sequences and proteins comprising these fragments are also disclosed.
摘要翻译： WO99 / 36544公开了大量来自脑膜炎奈瑟球菌的蛋白质。 本发明涉及包含至少一种抗原决定簇的那些蛋白质的片段。 还公开了包含这些片段的同源序列和蛋白质。
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公开(公告)号：US07612192B2
公开(公告)日：2009-11-03
申请号：US10915740
申请日：2004-08-11
申请人： Claire Marie Fraser , Erin Kathleen Hickey , Jeremy D. Peterson , Herve Tettelin , Craig Ventor , Vega Masignani , Cesira Galeotti , Marirosa Mora , Giulio Ratti , Maria Scarselli , Vincenzo Scarlato , Rino Rappuoli , Mariagrazia Pizza , Guido Grandi
发明人： Claire Marie Fraser , Erin Kathleen Hickey , Jeremy D. Peterson , Herve Tettelin , Craig Ventor , Vega Masignani , Cesira Galeotti , Marirosa Mora , Giulio Ratti , Maria Scarselli , Vincenzo Scarlato , Rino Rappuoli , Mariagrazia Pizza , Guido Grandi
CPC分类号： C07K14/22 , A61K38/00 , A61K39/00 , C12Q1/689 , C12Q2600/156
摘要： The invention provides methods of obtaining immunogenic proteins from genomic sequences including Neisseria, including the amino acid sequences and the corresponding nucleotide sequences, as well as the genomic sequence of Neisseria meningitidis B. The proteins so obtained are useful antigens for vaccines, immunogenic compositions, and/or diagnostics.
摘要翻译： 本发明提供了从包括奈瑟氏球菌在内的基因组序列获得免疫原性蛋白质的方法，包括氨基酸序列和相应的核苷酸序列，以及脑膜炎奈瑟氏球菌B的基因组序列。如此获得的蛋白质是疫苗，免疫原性组合物和 /或诊断。
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