公开(公告)号：US20050234581A1

公开(公告)日：2005-10-20

申请号：US11143079

申请日：2005-06-02

申请人： Vern Hoppes ,  Larry Kriener ,  Matthew Pipho ,  Joshua Edgin ,  James Mitchell ,  Ibrahim Shehata ,  Anthony Rath ,  Robert Mills ,  Michael Osborn ,  Mark Smith ,  Terry Phillips ,  Kevin Bortolazzo ,  David Sink ,  Joel Myers ,  Kenneth Kresser ,  Gary Miner ,  Lesley McNaught

发明人： Vern Hoppes ,  Larry Kriener ,  Matthew Pipho ,  Joshua Edgin ,  James Mitchell ,  Ibrahim Shehata ,  Anthony Rath ,  Robert Mills ,  Michael Osborn ,  Mark Smith ,  Terry Phillips ,  Kevin Bortolazzo ,  David Sink ,  Joel Myers ,  Kenneth Kresser ,  Gary Miner ,  Lesley McNaught

IPC分类号： G05B19/418 ,  G06F11/30 ,  G06F19/00

CPC分类号： G05B19/41805 ,  G05B19/4184 ,  G05B2219/31059 ,  G05B2219/31455 ,  G05B2219/31461 ,  G05B2219/36371 ,  Y02P90/04 ,  Y02P90/14

摘要： Interfaces are provided which integrate mistake-proofing concepts in a way easily understandable by the operator and easily configured by a manufacturing engineer. As mistake-proofing concepts are developed tables are populated and associated with specific assembly processes. Sensors are employed to monitor parts selection and tool usage. Sensors used for tool use and parts selection, error messages and actions to be performed or monitored are all defined and related in the tables and in turn to specific assembly orders. The tables are also populated with logic pointers, which are referenced by a Process Logic Control (PLC) unit that has been programmed to recall and carry out infinitely variable monitoring or control of the assembly process. For example when a particular order has been identified to the PLC by way of a scanned barcode or other means, a bill of material and assembly sequence is provided to the operator by appropriate means such as a CRT monitor. Parts bins and assembly points may be indicated by visual or other means to indicate parts and tools to be used and assembly points. Sensors determine when the proper part has been selected for the particular assembly step and/or whether the appropriate tool is used. The PLC then provides feedback to the operator to indicate whether all necessary steps have been accomplished in the proper order, with the proper parts using the proper tools. The PLC will provide the operator with understandable error messages indicating when a step has been improperly completed. The PLC can also control stops on the line to prevent the assembly from moving forward until all steps have been completed according to the specific order program. An override means may also be provided to bypass the PLC controls in which case an error log is compiled and an automated message is sent to. supervisory personnel indicating that the system was overridden by the operator and follow up action is required.

公开(公告)号：US20050222703A1

公开(公告)日：2005-10-06

申请号：US11143211

申请日：2005-06-02

申请人： Vern Hoppes ,  Larry Kriener ,  Matthew Pipho ,  Joshua Edgin ,  James Mitchell ,  Ibrahim Shehata ,  Anthony Rath ,  Robert Mills ,  Michael Osborn ,  Mark Smith ,  Terry Phillips ,  Kevin Bortolazzo ,  Dave Sink ,  Joel Myers ,  Kenneth Kresser ,  Gary Miner ,  Lesley McNaught

发明人： Vern Hoppes ,  Larry Kriener ,  Matthew Pipho ,  Joshua Edgin ,  James Mitchell ,  Ibrahim Shehata ,  Anthony Rath ,  Robert Mills ,  Michael Osborn ,  Mark Smith ,  Terry Phillips ,  Kevin Bortolazzo ,  Dave Sink ,  Joel Myers ,  Kenneth Kresser ,  Gary Miner ,  Lesley McNaught

IPC分类号： G05B19/418 ,  G06F11/30 ,  G06F19/00

CPC分类号： G05B19/41805 ,  G05B19/4184 ,  G05B2219/31059 ,  G05B2219/31455 ,  G05B2219/31461 ,  G05B2219/36371 ,  Y02P90/04 ,  Y02P90/14

摘要： Interfaces are provided which integrate mistake-proofing concepts in a way easily understandable by the operator and easily configured by a manufacturing engineer. As mistake-proofing concepts are developed tables are populated and associated with specific assembly processes. Sensors are employed to monitor parts selection and tool usage. Sensors used for tool use and parts selection, error messages and actions to be performed or monitored are all defined and related in the tables and in turn to specific assembly orders. The tables are also populated with logic pointers, which are referenced by a Process Logic Control (PLC) unit that has been programmed to recall and carry out infinitely variable monitoring or control of the assembly process. For example when a particular order has been identified to the PLC by way of a scanned barcode or other means, a bill of material and assembly sequence is provided to the operator by appropriate means such as a CRT monitor. Parts bins and assembly points may be indicated by visual or other means to indicate parts and tools to be used and assembly points. Sensors determine when the proper part has been selected for the particular assembly step and/or whether the appropriate tool is used. The PLC then provides feedback to the operator to indicate whether all necessary steps have been accomplished in the proper order, with the proper parts using the proper tools. The PLC will provide the operator with understandable error messages indicating when a step has been improperly completed. The PLC can also control stops on the line to prevent the assembly from moving forward until all steps have been completed according to the specific order program. An override means may also be provided to bypass the PLC controls in which case an error log is compiled and an automated message is sent to supervisory personnel indicating that the system was overridden by the operator and follow up action is required.

公开(公告)号：US20050222702A1

公开(公告)日：2005-10-06

申请号：US11143062

申请日：2005-06-02

申请人： Vern Hoppes ,  Larry Kriener ,  Matthew Pipho ,  Joshua Edgin ,  James Mitchell ,  Ibrahim Shehata ,  Anthony Rath ,  Robert Mills ,  Michael Osborn ,  Mark Smith ,  Terry Phillips ,  Kevin Bortolazzo ,  Dave Sink ,  Joel Myers ,  Kenneth Kresser ,  Gary Miner ,  Lesley McNaught

发明人： Vern Hoppes ,  Larry Kriener ,  Matthew Pipho ,  Joshua Edgin ,  James Mitchell ,  Ibrahim Shehata ,  Anthony Rath ,  Robert Mills ,  Michael Osborn ,  Mark Smith ,  Terry Phillips ,  Kevin Bortolazzo ,  Dave Sink ,  Joel Myers ,  Kenneth Kresser ,  Gary Miner ,  Lesley McNaught

IPC分类号： G05B19/418 ,  G06F11/30 ,  G06F19/00

CPC分类号： G05B19/41805 ,  G05B19/4184 ,  G05B2219/31059 ,  G05B2219/31455 ,  G05B2219/31461 ,  G05B2219/36371 ,  Y02P90/04 ,  Y02P90/14

摘要： Interfaces are provided which integrate mistake-proofing concepts in a way easily understandable by the operator and easily configured by a manufacturing engineer. As mistake-proofing concepts are developed tables are populated and associated with specific assembly processes. Sensors are employed to monitor parts selection and tool usage. Sensors used for tool use and parts selection, error messages and actions to be performed or monitored are all defined and related in the tables and in turn to specific assembly orders. The tables are also populated with logic pointers, which are referenced by a Process Logic Control (PLC) unit that has been programmed to recall and carry out infinitely variable monitoring or control of the assembly process. For example when a particular order has been identified to the PLC by way of a scanned barcode or other means, a bill of material and assembly sequence is provided to the operator by appropriate means such as a CRT monitor. Parts bins and assembly points may be indicated by visual or other means to indicate parts and tools to be used and assembly points. Sensors determine when the proper part has been selected for the particular assembly step and/or whether the appropriate tool is used. The PLC then provides feedback to the operator to indicate whether all necessary steps have been accomplished in the proper order, with the proper parts using the proper tools. The PLC will provide the operator with understandable error messages indicating when a step has been improperly completed. The PLC can also control stops on the line to prevent the assembly from moving forward until all steps have been completed according to the specific order program. An override means may also be provided to bypass the PLC controls in which case an error log is compiled and an automated message is sent to supervisory personnel indicating that the system was overridden by the operator and follow up action is required.

公开(公告)号：US20050209724A1

公开(公告)日：2005-09-22

申请号：US11143066

申请日：2005-06-02

申请人： Vern Hoppes ,  Larry Kriener ,  Matthew Pipho ,  Joshua Edgin ,  James Mitchell ,  Ibrahim Shehata ,  Anthony Rath ,  Robert Mills ,  Michael Osborn ,  Mark Smith ,  Terry Phillips ,  Kevin Bortolazzo ,  Dave Sink ,  Joel Myers ,  Kenneth Kresser ,  Gary Miner ,  Lesley McNaught

发明人： Vern Hoppes ,  Larry Kriener ,  Matthew Pipho ,  Joshua Edgin ,  James Mitchell ,  Ibrahim Shehata ,  Anthony Rath ,  Robert Mills ,  Michael Osborn ,  Mark Smith ,  Terry Phillips ,  Kevin Bortolazzo ,  Dave Sink ,  Joel Myers ,  Kenneth Kresser ,  Gary Miner ,  Lesley McNaught

IPC分类号： G05B19/418 ,  G06F11/30 ,  G06F19/00

CPC分类号： G05B19/41805 ,  G05B19/4184 ,  G05B2219/31059 ,  G05B2219/31455 ,  G05B2219/31461 ,  G05B2219/36371 ,  Y02P90/04 ,  Y02P90/14

摘要： Interfaces are provided which integrate mistake-proofing concepts in a way easily understandable by the operator and easily configured by a manufacturing engineer. As mistake-proofing concepts are developed tables are populated and associated with specific assembly processes. Sensors are employed to monitor parts selection and tool usage. Sensors used for tool use and parts selection, error messages and actions to be performed or monitored are all defined and related in the tables and in turn to specific assembly orders. The tables are also populated with logic pointers, which are referenced by a Process Logic Control (PLC) unit that has been programmed to recall and carry out infinitely variable monitoring or control of the assembly process. For example when a particular order has been identified to the PLC by way of a scanned barcode or other means, a bill of material and assembly sequence is provided to the operator by appropriate means such as a CRT monitor. Parts bins and assembly points may be indicated by visual or other means to indicate parts and tools to be used and assembly points. Sensors determine when the proper part has been selected for the particular assembly step and/or whether the appropriate tool is used. The PLC then provides feedback to the operator to indicate whether all necessary steps have been accomplished in the proper order, with the proper parts using the proper tools. The PLC will provide the operator with understandable error messages indicating when a step has been improperly completed. The PLC can also control stops on the line to prevent the assembly from moving forward until all steps have been completed according to the specific order program. An override means may also be provided to bypass the PLC controls in which case an error log is compiled and an automated message is sent to supervisory personnel indicating that the system was overridden by the operator and follow up action is required.

公开(公告)号：US11951746B2

公开(公告)日：2024-04-09

申请号：US17429748

申请日：2020-03-06

申请人： James R. Pryde ,  Mark Smith ,  Robert Hargreaves

发明人： James R. Pryde ,  Mark Smith ,  Robert Hargreaves

IPC分类号： B41J2/175 ,  G03G15/08

CPC分类号： B41J2/17523 ,  G03G15/0877

摘要： A device (1) for controlling user access to at least one container (4) for dispensing printing material housed by a printing apparatus (5), the device (1) comprising an openable and closable barrier (2) corresponding to the container (4) and a lock for locking the barrier (2) in a closed position. The lock is overlapped by at least a portion of the barrier (2) both when the barrier (2) is in the closed position and when the barrier (2) is in an open position.

公开(公告)号：US20170206608A1

公开(公告)日：2017-07-20

申请号：US15403374

申请日：2017-01-11

申请人： Mark Smith

发明人： Mark Smith

IPC分类号： G06Q40/08 ,  G06Q40/00 ,  G06Q40/06

CPC分类号： G06Q40/08 ,  G06Q40/06 ,  G06Q40/10

摘要： A Horizontally-Linked Reinsurance Network (HLRN) formed of a plurality of small insurance companies (as defined by applicable law, e.g. U.S.C. §831(b)) that is established and managed by a network administrator presents a new approach to harnessing the benefits of small insurance companies while mitigating the drawbacks of small insurance companies. This system uses a rules-based approach and algorithm to select, allocate, optimize and manage the individual risk portfolio of independent small insurance companies so as to preserve their status as a small insurance company while diversifying risk. Further, network administrator will perform the management functions if the HLRN. This allows investors or persons who would not otherwise own an insurance company to invest in a new asset class which by its nature demonstrates a non-correlation to traditional investment markets and carries both unique return and tax properties.

公开(公告)号：USD729041S1

公开(公告)日：2015-05-12

申请号：US29433547

申请日：2012-10-01

申请人： Mark Smith

设计人： Mark Smith

公开(公告)号：US20150038409A1

公开(公告)日：2015-02-05

申请号：US14097818

申请日：2013-12-05

申请人： Nikolaos Tezapsidis ,  Steven Greco ,  Mark Smith

发明人： Nikolaos Tezapsidis ,  Steven Greco ,  Mark Smith

IPC分类号： A61K38/22 ,  A61K31/7056

CPC分类号： A61K38/22 ,  A61K31/7056 ,  A61K38/2264 ,  A61K45/06 ,  C12Q1/485 ,  G01N33/5058 ,  G01N2800/2821 ,  G01N2800/2828 ,  A61K2300/00

摘要： The present disclosure provides compositions containing a leptin product and methods of clinical therapy and diagnostic methods for progressive cognitive disorders. According to one aspect, the described invention provides a method for treating a progressive cognitive disorder. According to another aspect, the described invention provides a method for improving resilience of cognitive function in a subject in need thereof. According to another aspect, the described invention provides a method for identifying an effective therapeutic agent for treating a progressive cognitive dysfunction disease or disorder that results from at least one of accumulation of Aβ, hyperphosphorylation of tau, or accumulation of neurofibrillary tangles.

摘要翻译： 本公开提供了含有瘦素产物的组合物和用于进行性认知障碍的临床治疗和诊断方法的方法。 根据一个方面，所述发明提供了治疗进行性认知障碍的方法。 根据另一方面，本发明提供了一种用于提高有需要的受试者的认知功能的弹性的方法。 根据另一方面，所述发明提供了鉴定用于治疗进行性认知功能障碍疾病或病症的有效治疗剂的方法，所述有效治疗剂由A和BGR的累积，tau的高度磷酸化或神经原纤维缠结的积累中的至少一种引起。

公开(公告)号：US08795194B2

公开(公告)日：2014-08-05

申请号：US12058910

申请日：2008-03-31

申请人： Mark Howard ,  Mark Smith

发明人： Mark Howard ,  Mark Smith

IPC分类号： A61B10/02 ,  A61M1/00 ,  B01D25/00

CPC分类号： C12N5/0653 ,  A61B10/025 ,  A61B10/0283 ,  A61B17/1635 ,  A61B17/32002 ,  A61B17/3205 ,  A61B2017/00969 ,  A61B2217/005 ,  A61M1/00 ,  A61M1/0056 ,  A61M2202/0014 ,  A61M2202/08

摘要： The present disclosure relates to a tissue collection apparatus. The tissue collection apparatus comprises a housing defining an inlet and an outlet, a first filter disposed within the housing, a second filter disposed within the housing, the second filter configured to isolate tissue particles of a desired size that pass through the first filter under the application of an aspiration force applied through the housing. A method of harvesting tissue is also disclosed.

摘要翻译： 本公开涉及一种组织收集装置。 所述组织收集装置包括限定入口和出口的壳体，设置在所述壳体内的第一过滤器，设置在所述壳体内的第二过滤器，所述第二过滤器被配置为将通过所述第一过滤器的所需尺寸的组织颗粒隔开， 施加通过壳体施加的抽吸力。 还公开了收获组织的方法。

公开(公告)号：US08642543B2

公开(公告)日：2014-02-04

申请号：US12470427

申请日：2009-05-21

申请人： Nikolaos Tezapsidis ,  Steven Greco ,  Mark Smith

发明人： Nikolaos Tezapsidis ,  Steven Greco ,  Mark Smith

IPC分类号： A61K38/22

CPC分类号： A61K38/2264 ,  A61K38/22 ,  A61K38/28 ,  A61K45/06 ,  A61K2300/00

摘要： The described invention provides methods for treating or preventing progression of a progressive cognitive disease, disorder or condition, and methods for improving resilience of cognitive function in a subject in need thereof.

摘要翻译： 所述发明提供了用于治疗或预防进行性认知疾病，病症或病症进展的方法，以及用于在有需要的受试者中提高认知功能的弹性的方法。