公开(公告)号：US10760058B2

公开(公告)日：2020-09-01

申请号：US15590475

申请日：2017-05-09

申请人： Vivex Biomedical Inc.

发明人： Timothy Ganey ,  Wendy W. Weston ,  Miguel Quevedo ,  Stuart Oglesby ,  Gaetan Jean-Robert Delcroix ,  Paul C. Schiller ,  Gianluca D'Ippolito

IPC分类号： C12N5/077 ,  A61K35/28 ,  A61K35/32 ,  A61L27/36 ,  A61L27/38 ,  A61L27/44 ,  A61L27/58 ,  A61L27/50 ,  A01N1/02 ,  A61L27/54 ,  A61K35/12

摘要： A biological composition has a mixture of mechanically selected allogeneic biologic material derived from bone marrow. The mixture has non-whole cellular components including vesicular components and active and inactive components of biological activity, cell fragments, cellular excretions, cellular derivatives, and extracellular components. The mixture including non-whole cell fractions including one or more of exosomes, transcriptosomes, proteasomes, membrane rafts, lipid rafts. The mixture is compatible with biologic function.

公开(公告)号：US20170239390A1

公开(公告)日：2017-08-24

申请号：US15591513

申请日：2017-05-10

申请人： Vivex Biomedical Inc.

发明人： Timothy Ganey ,  Wendy W. Weston ,  Miguel Quevedo ,  Stuart Oglesby ,  Gaetan Jean-Robert Delcroix ,  Paul C. Schiller ,  Gianluca D'Ippolito

IPC分类号： A61L27/36 ,  A01N1/02 ,  A61L27/54 ,  A61K35/28 ,  A61K35/32

CPC分类号： C12N5/0669 ,  A01N1/0221 ,  A01N1/0284 ,  A61K35/28 ,  A61K35/32 ,  A61K2035/124 ,  A61K2300/00 ,  A61L27/3604 ,  A61L27/3608 ,  A61L27/365 ,  A61L27/3691 ,  A61L27/3834 ,  A61L27/446 ,  A61L27/50 ,  A61L27/54 ,  A61L27/58 ,  A61L2430/00 ,  A61L2430/02 ,  C08L89/00

摘要： A biological composition has a mixture of mechanically selected allogeneic biologic material derived from bone marrow. The mixture has non-whole cellular components including vesicular components and active and inactive components of biological activity, cell fragments, cellular excretions, cellular derivatives, and extracellular components. The mixture is compatible with biologic function.

公开(公告)号：US10513690B2

公开(公告)日：2019-12-24

申请号：US15591513

申请日：2017-05-10

申请人： Vivex Biomedical Inc.

发明人： Timothy Ganey ,  Wendy W. Weston ,  Miguel Quevedo ,  Stuart Oglesby ,  Gaetan Jean-Robert Delcroix ,  Paul C. Schiller ,  Gianluca D'Ippolito

IPC分类号： C12N5/077 ,  A61K35/28 ,  A61K35/32 ,  A61L27/36 ,  A61L27/38 ,  A61L27/44 ,  A61L27/50 ,  A01N1/02 ,  A61L27/54 ,  A61K35/12

摘要： A biological composition has a mixture of mechanically selected allogeneic biologic material derived from bone marrow. The mixture has non-whole cellular components including vesicular components and active and inactive components of biological activity, cell fragments, cellular excretions, cellular derivatives, and extracellular components. The mixture is compatible with biologic function.

公开(公告)号：US20170247659A1

公开(公告)日：2017-08-31

申请号：US15590444

申请日：2017-05-09

申请人： Vivex Biomedical Inc.

发明人： Timothy Ganey ,  Wendy W. Weston ,  Miguel Quevedo ,  Stuart Oglesby ,  Gaetan Jean-Robert Delcroix ,  Paul C. Schiller ,  Gianluca D'Ippolito

IPC分类号： C12N5/077 ,  A61L27/36 ,  A01N1/02 ,  A61K35/28 ,  A61K35/32

CPC分类号： C12N5/0669 ,  A01N1/0221 ,  A01N1/0284 ,  A61K35/28 ,  A61K35/32 ,  A61K2035/124 ,  A61K2300/00 ,  A61L27/3604 ,  A61L27/3608 ,  A61L27/365 ,  A61L27/3691 ,  A61L27/3834 ,  A61L27/446 ,  A61L27/50 ,  A61L27/54 ,  A61L27/58 ,  A61L2430/00 ,  A61L2430/02 ,  C08L89/00

摘要： A biological composition has a mixture of mechanically selected allogeneic biologic material derived from bone marrow. The mixture has non-whole cellular components including vesicular components and active and inactive components of biological activity, cell fragments, cellular excretions, cellular derivatives, and extracellular components. The mixture including non-whole cell fractions including one or more of exosomes, transcriptosomes, proteasomes, membrane rafts, lipid rafts. The mixture is compatible with biologic function.

公开(公告)号：US09687511B2

公开(公告)日：2017-06-27

申请号：US14682523

申请日：2015-04-09

申请人： Vivex Biomedical Inc.

发明人： Wendy W. Weston ,  Miguel Quevedo ,  Stuart Oglesby ,  Gaëtan Jean-Robert Delcroix ,  Paul C. Schiller ,  Gianluca D'Ippolito ,  Timothy Ganey

IPC分类号： A61K35/28 ,  A61K35/32 ,  A61L27/36 ,  A61L27/50 ,  A01N1/02 ,  A61L27/38 ,  A61L27/44 ,  A61K35/12

CPC分类号： C12N5/0669 ,  A01N1/0221 ,  A01N1/0284 ,  A61K35/28 ,  A61K35/32 ,  A61K2035/124 ,  A61K2300/00 ,  A61L27/3604 ,  A61L27/3608 ,  A61L27/365 ,  A61L27/3691 ,  A61L27/3834 ,  A61L27/446 ,  A61L27/50 ,  A61L27/54 ,  A61L27/58 ,  A61L2430/00 ,  A61L2430/02 ,  C08L89/00

摘要： A biological composition has a mixture of mechanically selected allogeneic biologic material derived from bone marrow. The mixture has non-whole cellular components including vesicular components and active and inactive components of biological activity, cell fragments, cellular excretions, cellular derivatives, and extracellular components. The mixture including non-whole cell fractions including one or more of exosomes, transcriptosomes, proteasomes, membrane rafts, lipid rafts. The mixture is compatible with biologic function.

公开(公告)号：US09675643B2

公开(公告)日：2017-06-13

申请号：US14683221

申请日：2015-04-10

申请人： Vivex Biomedical Inc.

发明人： Wendy W. Weston ,  Miguel Quevedo ,  Stuart Oglesby ,  Gaëtan Jean-Robert Delcroix ,  Paul C. Schiller ,  Gianluca D'Ippolito ,  Timothy Ganey

IPC分类号： A61K35/28 ,  A61K35/32 ,  A61L27/36 ,  A61L27/50 ,  A01N1/02 ,  A61L27/38 ,  A61L27/44 ,  A61K35/12

CPC分类号： C12N5/0669 ,  A01N1/0221 ,  A01N1/0284 ,  A61K35/28 ,  A61K35/32 ,  A61K2035/124 ,  A61K2300/00 ,  A61L27/3604 ,  A61L27/3608 ,  A61L27/365 ,  A61L27/3691 ,  A61L27/3834 ,  A61L27/446 ,  A61L27/50 ,  A61L27/54 ,  A61L27/58 ,  A61L2430/00 ,  A61L2430/02 ,  C08L89/00

摘要： A biological composition has a mixture of mechanically selected allogeneic biologic material derived from bone marrow. The mixture has non-whole cellular components including vesicular components and active and inactive components of biological activity, cell fragments, cellular excretions, cellular derivatives, and extracellular components. The mixture is compatible with biologic function.

公开(公告)号：US20190151506A1

公开(公告)日：2019-05-23

申请号：US15818147

申请日：2017-11-20

申请人： Vivex Biomedical Inc.

发明人： Timothy Ganey ,  Wendy W. Weston ,  Miguel Quevedo ,  Stuart Oglesby ,  Tracy Scott Anderson

IPC分类号： A61L27/36 ,  A61K35/28

摘要： A biological composition has a mixture of mechanically selected allogeneic biologic material derived from bone marrow. The mixture has non-whole cellular components including vesicular components and active and inactive components of biological activity, cell fragments, cellular excretions, cellular derivatives, and extracellular components. The mixture including non-whole cell fractions including one or more of exosomes, transcriptosomes, proteasomes, membrane rafts, lipid rafts. The mixture is compatible with biologic function.

公开(公告)号：US20180334655A1

公开(公告)日：2018-11-22

申请号：US16049215

申请日：2018-07-30

申请人： Vivex Biomedical, Inc.

发明人： Timothy Ganey ,  Wendy W. Weston ,  Miguel Quevedo ,  Stuart Oglesby ,  Gaetan Jean-Robert Delcroix ,  Paul C. Schiller ,  Gianluca D'Ippolito

IPC分类号： C12N5/077 ,  C08L89/00 ,  A61L27/36 ,  A01N1/02 ,  A61K35/28 ,  A61L27/58 ,  A61L27/54 ,  A61L27/50 ,  A61L27/44 ,  A61L27/38 ,  A61K35/32 ,  A61K35/12

摘要： A biological composition has a mixture of mechanically selected allogeneic biologic material derived from bone marrow. The mixture has non-whole cellular components including vesicular components and active and inactive components of biological activity, cell fragments, cellular excretions, cellular derivatives, and extracellular components. The mixture is compatible with biologic function.

公开(公告)号：US20160256490A1

公开(公告)日：2016-09-08

申请号：US14682523

申请日：2015-04-09

申请人： Vivex Biomedical Inc.

发明人： Wendy W. Weston ,  Miguel Quevedo ,  Stuart Oglesby ,  Gaëtan Jean-Robert Delcroix ,  Paul C. Schiller ,  Gianluca D'Ippolito ,  Timothy Ganey

IPC分类号： A61K35/28 ,  A61L27/36 ,  A61L27/50 ,  A61K35/32

CPC分类号： C12N5/0669 ,  A01N1/0221 ,  A01N1/0284 ,  A61K35/28 ,  A61K35/32 ,  A61K2035/124 ,  A61K2300/00 ,  A61L27/3604 ,  A61L27/3608 ,  A61L27/365 ,  A61L27/3691 ,  A61L27/3834 ,  A61L27/446 ,  A61L27/50 ,  A61L27/54 ,  A61L27/58 ,  A61L2430/00 ,  A61L2430/02 ,  C08L89/00

摘要： A biological composition has a mixture of mechanically selected allogeneic biologic material derived from bone marrow. The mixture has non-whole cellular components including vesicular components and active and inactive components of biological activity, cell fragments, cellular excretions, cellular derivatives, and extracellular components. The mixture including non-whole cell fractions including one or more of exosomes, transcriptosomes, proteasomes, membrane rafts, lipid rafts. The mixture is compatible with biologic function.

摘要翻译： 生物组合物具有衍生自骨髓的机械选择的同种异体生物材料的混合物。 该混合物具有非全细胞组分，包括水泡组分和生物活性的活性和非活性组分，细胞碎片，细胞排泄物，细胞衍生物和细胞外组分。 混合物包括非全细胞级分，包括一种或多种外来体，转录组，蛋白酶体，膜筏，脂筏。 该混合物与生物功能相容。

公开(公告)号：US20170240862A1

公开(公告)日：2017-08-24

申请号：US15590475

申请日：2017-05-09

申请人： Vivex Biomedical Inc.

发明人： Timothy Ganey ,  Wendy W. Weston ,  Miguel Quevedo ,  Stuart Oglesby ,  Gaetan Jean-Robert Delcroix ,  Paul C. Schiller ,  Gianluca D'Ippolito

IPC分类号： C12N5/077 ,  A01N1/02 ,  A61L27/36 ,  A61K35/32

摘要： A biological composition has a mixture of mechanically selected allogeneic biologic material derived from bone marrow. The mixture has non-whole cellular components including vesicular components and active and inactive components of biological activity, cell fragments, cellular excretions, cellular derivatives, and extracellular components. The mixture including non-whole cell fractions including one or more of exosomes, transcriptosomes, proteasomes, membrane rafts, lipid rafts. The mixture is compatible with biologic function.