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    Method for identifying active substances
    5.
    发明授权
    Method for identifying active substances 失效
    识别活性物质的方法

    公开(公告)号：US06429015B1

    公开(公告)日：2002-08-06

    申请号：US09508416

    申请日：2000-05-22

    申请人： David Moss ,  Herbert Platsch ,  Kathrin Füchsle ,  Ralf Masuch

    发明人： David Moss ,  Herbert Platsch ,  Kathrin Füchsle ,  Ralf Masuch

    IPC分类号： G01N2135

    CPC分类号： G01N33/68 ,  G01N1/14 ,  G01N21/3577 ,  G01N35/08 ,  G01N35/1097 ,  Y10T436/143333

    摘要： The invention relates to a method and a device for identifying active substances in order to determine the formation of complexes between reactants. According to the inventive method, at least two reactants are mixed and made to react to form a complex. The infrared spectrum of the individual reactants which have not yet been reacted in the mixture is measured during a first time interval and at least a second infrared measurement is conducted to measure the complex formed by the reactants during a second interval. The difference between the two spectra measured during different moments is then determined. The reactants whose differential spectrum exhibits a band structure are selected as active substances.

    摘要翻译： 本发明涉及一种用于鉴定活性物质以确定反应物之间复合物形成的方法和装置。 根据本发明的方法，将至少两种反应物混合并使其反应以形成络合物。 在第一时间间隔内测量在混合物中尚未反应的各个反应物的红外光谱，并进行至少第二次红外测量以测量在第二时间间隔期间由反应物形成的络合物。 然后确定在不同时刻测量的两个光谱之间的差异。 选择差示光谱显示带结构的反应物作为活性物质。

    Method for Testing Substances or Mixtures of Substances,Use of Said Method and Corresponding Test Kits
    7.
    发明申请
    Method for Testing Substances or Mixtures of Substances,Use of Said Method and Corresponding Test Kits 审中-公开
    物质或物质混合物的测试方法，所述方法的使用和相应的测试试剂盒

    公开(公告)号：US20090123377A1

    公开(公告)日：2009-05-14

    申请号：US11921782

    申请日：2006-06-08

    申请人： Elard Jacob ,  Herbert Platsch ,  Gerhard Krennrich

    发明人： Elard Jacob ,  Herbert Platsch ,  Gerhard Krennrich

    IPC分类号： A61K49/00 ,  G01N33/53 ,  A61P43/00

    CPC分类号： G01N33/5014 ,  G01N33/5088 ,  G01N2333/70567

    摘要： The invention relates to a method for testing substances and mixtures of substances for toxic characteristics, to the use of said method and to corresponding test kits. The method is essentially based on the determination of a fatty acid binding protein from the liver, L-FABP. The use of said method provides an early indication of carcinogenic and tumour-promoting characteristics of the tested substance or mixture of substances.

    摘要翻译： 本发明涉及一种用于检测毒性特性的物质和物质的混合物的方法，所述方法和相应的试剂盒的使用。 该方法基本上是基于来自肝脏的脂肪酸结合蛋白L-FABP的测定。 所述方法的使用提供了被测物质或物质混合物的致癌和促进肿瘤特征的早期指示。