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1.发明申请公开(公告)号：US20140039318A1
公开(公告)日：2014-02-06
申请号：US14044842
申请日：2013-10-02
IPC分类号： A61B8/08
CPC分类号： A61B8/0825 , A61B8/5238 , G06T7/0012 , G06T2207/10132 , G06T2207/30068
摘要： A method and system for processing and displaying breast ultrasound information is described. A 2D feature weighted volumetric coronal image as a “guide” or “road map” is generated from the 3D ultrasound data volume to represent the 3D dataset with the goal of emphasizing abnormalities within the breast while excluding non-breast structures, particularly those external to the breast such as ribs and chest wall.
摘要翻译： 描述了一种用于处理和显示乳房超声信息的方法和系统。 从3D超声数据体积中生成2D特征加权体积冠状图像作为“导向”或“路线图”，以表示3D数据集，目的是强调乳房内的异常，同时排除非乳房结构，特别是外部 乳房如肋骨和胸壁。
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公开(公告)号：US09826958B2
公开(公告)日：2017-11-28
申请号：US14044842
申请日：2013-10-02
CPC分类号： A61B8/0825 , A61B8/5238 , G06T7/0012 , G06T2207/10132 , G06T2207/30068
摘要： A method and system for processing and displaying breast ultrasound information is described. A 2D feature weighted volumetric coronal image as a “guide” or “road map” is generated from the 3D ultrasound data volume to represent the 3D dataset with the goal of emphasizing abnormalities within the breast while excluding non-breast structures, particularly those external to the breast such as ribs and chest wall.
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3.发明申请Reduced Image Reading Time and Improved Patient Flow in Automated Breast Ultrasound Using Enchanced, Whole Breast Navigator Overview Images 有权使用加强的整个乳房导航器，自动乳房超声减少图像阅读时间和改善患者流量概述图像公开(公告)号：US20140343420A1
公开(公告)日：2014-11-20
申请号：US14448607
申请日：2014-07-31
申请人： Wei Zhang , Shih-Ping Wang , Alexander Schneider , Harlan Romsdahl , Thomas Neff
发明人： Wei Zhang , Shih-Ping Wang , Alexander Schneider , Harlan Romsdahl , Thomas Neff
CPC分类号： A61B8/0825 , A61B8/13 , A61B8/403 , A61B8/469 , A61B8/5215 , G06T7/0012 , G06T2207/10132 , G06T2207/30068
摘要： A method and system acquiring, processing and displaying breast ultrasound images in a way that makes breast ultrasound screening more practical and thus more widely used, and reduces missing cancers in screening and diagnosis, using automated scanning of chestwardly compressed breasts with ultrasound. Enhanced, whole-breast navigator overview images are generated from scanning breasts with ultrasound that emphasize abnormalities in the breast while excluding obscuring influences of non-breast structures, particularly those external to the breast such as ribs and chest wall, and differentiating between likely malignant and likely benign abnormalities and otherwise enhancing the navigator overview image and other images, to thereby reduce the time to read, screen, or diagnose to practical time limits and also reduce screening or diagnostic errors.
摘要翻译： 一种方法和系统采用乳房超声检查更加实用，因此更广泛使用的方式获取，处理和显示乳房超声图像，并通过使用超声波胸部压缩乳房进行自动扫描，减少筛查和诊断中遗漏的癌症。 增强的全乳头导航仪概述图像是通过超声检查乳房产生的，该超声波强调乳房异常，同时排除非乳房结构（特别是乳房外部，如肋骨和胸壁）的模糊影响，并区分可能的恶性和 可能是良性异常，否则增强导航仪概览图像和其他图像，从而减少读取，屏幕或诊断到实际时间限制的时间，并减少筛查或诊断错误。
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4.发明授权Reduced image reading time and improved patient flow in automated breast ultrasound using enchanced, whole breast navigator overview images 有权使用强化的全乳腺导航仪概览图像，缩短了图像阅读时间并改善了自动乳房超声的患者流量公开(公告)号：US09439621B2
公开(公告)日：2016-09-13
申请号：US14448607
申请日：2014-07-31
申请人： Wei Zhang , Shih-Ping Wang , Alexander Schneider , Harlan Romsdahl , Thomas Neff
发明人： Wei Zhang , Shih-Ping Wang , Alexander Schneider , Harlan Romsdahl , Thomas Neff
CPC分类号： A61B8/0825 , A61B8/13 , A61B8/403 , A61B8/469 , A61B8/5215 , G06T7/0012 , G06T2207/10132 , G06T2207/30068
摘要： A method and system acquiring, processing and displaying breast ultrasound images in a way that makes breast ultrasound screening more practical and thus more widely used, and reduces missing cancers in screening and diagnosis, using automated scanning of chestwardly compressed breasts with ultrasound. Enhanced, whole-breast navigator overview images are generated from scanning breasts with ultrasound that emphasize abnormalities in the breast while excluding obscuring influences of non-breast structures, particularly those external to the breast such as ribs and chest wall, and differentiating between likely malignant and likely benign abnormalities and otherwise enhancing the navigator overview image and other images, to thereby reduce the time to read, screen, or diagnose to practical time limits and also reduce screening or diagnostic errors.
摘要翻译： 一种方法和系统采用乳房超声检查更加实用，因此更广泛使用的方式获取，处理和显示乳房超声图像，并通过使用超声波胸部压缩乳房进行自动扫描，减少筛查和诊断中遗漏的癌症。 增强的全乳头导航仪概述图像是通过超声检查乳房产生的，该超声波强调乳房异常，同时排除非乳房结构（特别是乳房外部，如肋骨和胸壁）的模糊影响，并区分可能的恶性和 可能是良性异常，否则增强导航仪概览图像和其他图像，从而减少读取，屏幕或诊断到实际时间限制的时间，并减少筛查或诊断错误。
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5.发明授权公开(公告)号：US09289183B2
公开(公告)日：2016-03-22
申请号：US13512164
申请日：2009-11-27
申请人： Nico Karssemeijer , Shih-Ping Wang
发明人： Nico Karssemeijer , Shih-Ping Wang
CPC分类号： A61B6/469 , A61B6/502 , G06F19/00 , G06F19/321 , G06T7/0014 , G06T2200/24 , G06T2207/20104 , G06T2207/30068
摘要： Methods and related systems provide an interactive user interface in which CAD results are displayed in such a way that they may be used for both interpretation of detected abnormalities and for avoiding perceptual oversights. The output of a (multi-view) computer aided detection system is presented to the reader of a screening case in two phases: (1) an interactive phase, and (2) a prompting phase. In the first phase the reader can probe image locations for CAD information. In the second phase regions identified as relevant by the CAD system and not yet probed by the reader are prompted or displayed to the user, as these may have been overlooked by the reader. The CAD results can be calibrated to a probability of malignancy.
摘要翻译： 方法和相关系统提供交互式用户界面，其中CAD结果以这样的方式显示，使得它们可以用于解释检测到的异常并且用于避免感知的疏忽。 （多视图）计算机辅助检测系统的输出向两个阶段的筛选案例的读者呈现：（1）交互式阶段，（2）提示阶段。 在第一阶段，读者可以探测CAD信息的图像位置。 在第二阶段，由CAD系统识别为尚未被读者探测的区域被提示或显示给用户，因为这些可能被读者忽视。 CAD结果可以校正为恶性肿瘤的概率。
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6.发明申请INTERACTIVE DISPLAY OF COMPUTER AIDED DETECTION RESULTS IN COMBINATION WITH QUANTITATIVE PROMPTS 有权计算机辅助检测结果与定量检测结果的交互显示公开(公告)号：US20130050239A1
公开(公告)日：2013-02-28
申请号：US13512164
申请日：2009-11-27
申请人： Nico Karssemeijer , Shih-Ping Wang
发明人： Nico Karssemeijer , Shih-Ping Wang
CPC分类号： A61B6/469 , A61B6/502 , G06F19/00 , G06F19/321 , G06T7/0014 , G06T2200/24 , G06T2207/20104 , G06T2207/30068
摘要： Methods and related systems are described for providing an interactive user interface in which CAD results are displayed in such a way that they may be used for both interpretation of detected abnormalities and for avoiding perceptual oversights. Systems are described in which the output of a (multi-view) computer aided detection system is presented to the reader of a screening case in two phases: (1) an interactive phase, and (2) a prompting phase. In the first phase the reader can probe image locations for CAD information. In the second phase regions identified as relevant by the CAD system and not yet probed by the reader are prompted or displayed to the user, as these may have been overlooked by the reader. The CAD results can be calibrated to a probability of malignancy.
摘要翻译： 描述了用于提供交互式用户界面的方法和相关系统，其中CAD结果以这样的方式显示，使得它们可以用于解释检测到的异常并且用于避免感知的疏忽。 描述了一种（多视图）计算机辅助检测系统的输出在两个阶段向筛选案例的读者呈现的系统：（1）交互式阶段，以及（2）提示阶段。 在第一阶段，读者可以探测CAD信息的图像位置。 在第二阶段，由CAD系统识别为尚未被读者探测的区域被提示或显示给用户，因为这些可能被读者忽视。 CAD结果可以校正为恶性肿瘤的概率。
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公开(公告)号：US08317702B2
公开(公告)日：2012-11-27
申请号：US10560200
申请日：2004-06-18
申请人： Zengpin Yu , Danhua Zhao , Thomas P. Neff , Wei Zhang , Shih-Ping Wang
发明人： Zengpin Yu , Danhua Zhao , Thomas P. Neff , Wei Zhang , Shih-Ping Wang
IPC分类号： A61B8/00
CPC分类号： A61B8/4477 , A61B8/0825 , A61B8/4281 , A61B8/4405 , A61B8/5238 , Y10T29/49005
摘要： A modular, flexible architecture for offering full-field breast ultrasound (FFBU) functionality and general-purpose ultrasound functionality in a single system is described. A conventional, general-purpose ultrasound system (202) is modified with an FFBU toolkit to create a dual-capability ultrasound system (200), the dual-capability ultrasound system (200) being able to accommodate both general-purpose ultrasound functionality and FFBU functionality, using a single ultrasound engine (112). Among other advantages, real-world clinical environments may enjoy cost savings for initial system procurement, space savings on clinic floors, easier and less expensive system upgrades, and the ability to use a single system and user interface for both FFBU screening and for follow-up diagnosis, biopsy, etc. Among other advantages from an ultrasound manufacturer's perspective are the ability to quickly and/or more easily come to market with an FFBU-related offering by modifying their existing general-purpose ultrasound systems (202) with FFBU toolkits to quickly create dual-capability ultrasound systems (200).
摘要翻译： 描述了在单个系统中提供全场乳房超声（FFBU）功能和通用超声功能的模块化，灵活的架构。 传统的通用超声系统（202）用FFBU工具包修改以创建双能力超声系统（200），双能力超声系统（200）能够容纳通用超声功能和FFBU 功能，使用单个超声引擎（112）。 除了其他优点之外，现实世界的临床环境可以节省初始系统采购成本，临床楼层节省空间，更便宜和更便宜的系统升级，以及使用单个系统和用户界面进行FFBU筛选和跟踪的功能， 诊断，活检等。超声波制造商的观点还有其他优点，即通过使用FFBU工具包修改现有的通用超声波系统（202），通过与FFBU相关的产品快速和/或更容易上市。 快速创建双功能超声系统（200）。
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8.发明申请公开(公告)号：US20110098566A1
公开(公告)日：2011-04-28
申请号：US12890374
申请日：2010-09-24
申请人： Wei ZHANG , Shih-Ping Wang , Jiayu Chen , Zengpin Yu , Tommy Earl Cupples , Thomas P. Neff , Michael E. Reed
发明人： Wei ZHANG , Shih-Ping Wang , Jiayu Chen , Zengpin Yu , Tommy Earl Cupples , Thomas P. Neff , Michael E. Reed
CPC分类号： A61B8/5238 , A61B6/463 , A61B6/502 , A61B6/5247 , A61B6/563 , A61B8/0825 , A61B8/13 , A61B8/406 , A61B8/4281 , A61B8/4405 , A61B8/462 , A61B8/463 , A61B8/465 , A61B8/466 , A61B8/467 , A61B8/565
摘要： Displaying breast ultrasound information on an interactive user interface is described, the user interface being useful in adjunctive ultrasound mammography environments and/or ultrasound-only mammography environments. Bilateral comparison is facilitated by a pairwise display of thick-slice images corresponding to analogous slab-like subvolumes in the left and right breasts. Coronal thick-slice imaging and convenient navigation on and among coronal thick-slice images is described. In one preferred embodiment, a nipple marker is displayed the coronal thick-slice image representing a projection of a nipple location thereupon. A convenient breast icon is also displayed including a cursor position indicator variably disposed thereon in a manner that reflects a relative position between the cursor and the nipple marker. Preferably, the breast icon is configured to at least roughly resemble a clock face, the center of the clock face representing the nipple marker location. Bookmark-centric and CAD-marker-centric navigation within and among thick-slice images is also described.
摘要翻译： 描述了在交互式用户界面上显示乳房超声信息，用户界面在辅助超声乳腺X线照相术环境和/或仅超声乳腺X线照相术环境中有用。 通过成对显示对应于左乳房和右乳房中类似的板状子体积的双层比较来促进双边比较。 描述了冠状厚片成像和冠状厚片图像之间和之间方便的导航。 在一个优选实施例中，乳头标记被显示为表示其上的乳头位置的投影的冠状厚片图像。 还显示方便的胸部图标，包括以反映光标和乳头标记之间的相对位置的方式可变地设置在其上的光标位置指示器。 优选地，乳房图标被配置为至少大致类似于时钟面，时钟面的中心表示乳头标记位置。 还描述了厚片图像内和书签中心和CAD标记为中心的导航。
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公开(公告)号：US20120095305A1
公开(公告)日：2012-04-19
申请号：US12815696
申请日：2010-06-15
申请人： Ming Wang , Shih-Ping Wang , Zengpin Yu , Wei Zhang
发明人： Ming Wang , Shih-Ping Wang , Zengpin Yu , Wei Zhang
IPC分类号： A61B5/1455 , A61B6/00
CPC分类号： A61B5/0075 , A61B5/103 , A61B5/14551
摘要： Methods, systems, and related computer program products for the non-invasive spectrophotometric monitoring of a biological volume having multiple tissue layers are described. Aggregate absorption and scattering properties are measured for each of a plurality of predetermined source-detector separation distances along a surface of the biological volume, the measurement being based on a model of the biological volume as a single-layer, semi-infinite, homogeneous volume. A predetermined multi-layer tissue model is retrieved that characterizes a mathematical relationship among (a) absorption and scattering properties of each layer of a multi-layer tissue structure, and (b) aggregate absorption and scattering properties of the multi-layer tissue structure as would be measured at selected source-detector separation distances along a surface thereof. The measured aggregate absorption and scattering properties are processed in conjunction with the predetermined multi-layer tissue model to compute therefrom a deep-layer-specific absorption property corresponding to the relatively deep tissue layer.
摘要翻译： 描述了用于非侵入式分光光度监测具有多个组织层的生物体积的方法，系统和相关的计算机程序产品。 测量沿着生物体积的表面的多个预定的源 - 检测器分离距离中的每一个的聚集吸收和散射性质，该测量基于生物体积的模型作为单层，半无限均质体积 。 检索预定的多层组织模型，其表征（a）多层组织结构的每层的吸收和散射性质之间的数学关系，以及（b）多层组织结构的聚集吸收和散射性质作为 将沿着其表面的选定的源 - 检测器间隔距离测量。 测量的聚集体吸收和散射性质与预定的多层组织模型结合进行处理，从而计算对应于相对较深的组织层的深层特异性吸收特性。
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10.发明授权公开(公告)号：US08162833B2
公开(公告)日：2012-04-24
申请号：US12890374
申请日：2010-09-24
申请人： Wei Zhang , Shih-Ping Wang , Jiayu Chen , Zengpin Yu , Tommy Earl Cupples , Thomas P. Neff , Michael E. Reed
发明人： Wei Zhang , Shih-Ping Wang , Jiayu Chen , Zengpin Yu , Tommy Earl Cupples , Thomas P. Neff , Michael E. Reed
IPC分类号： A61B8/00
CPC分类号： A61B8/5238 , A61B6/463 , A61B6/502 , A61B6/5247 , A61B6/563 , A61B8/0825 , A61B8/13 , A61B8/406 , A61B8/4281 , A61B8/4405 , A61B8/462 , A61B8/463 , A61B8/465 , A61B8/466 , A61B8/467 , A61B8/565
摘要： Displaying breast ultrasound information on an interactive user interface is described, the user interface being useful in adjunctive ultrasound mammography environments and/or ultrasound-only mammography environments. Bilateral comparison is facilitated by a pairwise display of thick-slice images corresponding to analogous slab-like subvolumes in the left and right breasts. Coronal thick-slice imaging and convenient navigation on and among coronal thick-slice images is described. In one preferred embodiment, a nipple marker is displayed the coronal thick-slice image representing a projection of a nipple location thereupon. A convenient breast icon is also displayed including a cursor position indicator variably disposed thereon in a manner that reflects a relative position between the cursor and the nipple marker. Preferably, the breast icon is configured to at least roughly resemble a clock face, the center of the clock face representing the nipple marker location. Bookmark-centric and CAD-marker-centric navigation within and among thick-slice images is also described.
摘要翻译： 描述了在交互式用户界面上显示乳房超声信息，用户界面在辅助超声乳腺X线照相术环境和/或仅超声乳腺X线照相术环境中有用。 通过成对显示对应于左乳房和右乳房中类似的板状子体积的双层比较来促进双边比较。 描述了冠状厚片成像和冠状厚片图像之间和之间方便的导航。 在一个优选实施例中，乳头标记被显示为表示其上的乳头位置的投影的冠状厚片图像。 还显示方便的胸部图标，包括以反映光标和乳头标记之间的相对位置的方式可变地设置在其上的光标位置指示器。 优选地，乳房图标被配置为至少大致类似于时钟面，时钟面的中心表示乳头标记位置。 还描述了厚片图像内和书签中心和CAD标记为中心的导航。
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