Controlled release carvedilol formulation
    1.
    发明授权
    Controlled release carvedilol formulation 有权
    卡维地洛控制释放制剂

    公开(公告)号:US08883207B2

    公开(公告)日:2014-11-11

    申请号:US13498751

    申请日:2010-09-29

    摘要: A controlled release carvedilol formulation for less frequent, preferably once daily administration is described. The controlled release formulation comprises a therapeutically effective amount of carvedilol or a pharmaceutically acceptable salt thereof, a matrix forming polymer, a solubility enhancer and a pharmaceutically acceptable carrier. In one embodiment, a controlled release formulation having a therapeutically effective amount of carvedilol is contained in two or more subunits having different release profiles. The controlled release formulation is usable in the treatment and/or prophylaxis of one or more conditions such as cardiovascular disorders.

    摘要翻译: 描述了用于较不频繁,优选每日一次施用的卡培他洛司他汀制剂。 控释制剂包含治疗有效量的卡维地洛或其药学上可接受的盐,基质形成聚合物,溶解度增强剂和药学上可接受的载体。 在一个实施方案中,具有治疗有效量的卡维地洛的控释制剂包含在具有不同释放曲线的两个或更多个亚基中。 控释制剂可用于治疗和/或预防一种或多种病症如心血管疾病。

    CONTROLLED RELEASE CARVEDILOL FORMULATION
    2.
    发明申请
    CONTROLLED RELEASE CARVEDILOL FORMULATION 有权
    控制释放卡维地洛配方

    公开(公告)号:US20120245212A1

    公开(公告)日:2012-09-27

    申请号:US13498751

    申请日:2010-09-29

    IPC分类号: A61K31/403 B29C43/52

    摘要: A controlled release carvedilol formulation for less frequent, preferably once daily administration is described. The controlled release formulation comprises a therapeutically effective amount of carvedilol or a pharmaceutically acceptable salt thereof, a matrix forming polymer, a solubility enhancer and a pharmaceutically acceptable carrier. In one embodiment, a controlled release formulation having a therapeutically effective amount of carvedilol is contained in two or more subunits having different release profiles. The controlled release formulation is usable in the treatment and/or prophylaxis of one or more conditions such as cardiovascular disorders.

    摘要翻译: 描述了用于较不频繁,优选每日一次施用的卡培他洛司他汀制剂。 控释制剂包含治疗有效量的卡维地洛或其药学上可接受的盐,基质形成聚合物,溶解度增强剂和药学上可接受的载体。 在一个实施方案中,具有治疗有效量的卡维地洛的控释制剂包含在具有不同释放曲线的两个或更多个亚基中。 控释制剂可用于治疗和/或预防一种或多种病症如心血管疾病。

    SELF-EMULSIFYING PHARMACEUTICAL COMPOSITIONS OF HYDROPHILIC DRUGS AND PREPARATION THEREOF
    3.
    发明申请
    SELF-EMULSIFYING PHARMACEUTICAL COMPOSITIONS OF HYDROPHILIC DRUGS AND PREPARATION THEREOF 审中-公开
    水解药物的自我发酵药物组合物及其制备方法

    公开(公告)号:US20100273730A1

    公开(公告)日:2010-10-28

    申请号:US12767293

    申请日:2010-04-26

    摘要: The present invention provides an oral self micro-emulsifying pharmaceutical composition of a hydrophilic drug or a pharmaceutically acceptable salt thereof which, in addition to the hydrophilic drug, one or more solvents for solving the hydrophilic drug to form a drug-solvent solution and a surfactant system, further comprises one or more hydrophilic carrier which are compatible with said drug-solvent solution and the surfactant system. The oral self micro-emulsifying pharmaceutical composition of the invention exhibits comparative bioavailability to that of the hydrophilic drug through injection and is stable during storage. A method for preparing the oral self micro-emulsifying pharmaceutical composition is also provided.

    摘要翻译: 本发明提供一种亲水药物或其药学上可接受的盐的口服自微乳化药物组合物,其除了亲水性药物之外,还可使用一种或多种用于溶解亲水药物以形成药物溶剂溶液和表面活性剂的溶剂 还包括与所述药物 - 溶剂溶液和表面活性剂体系相容的一种或多种亲水载体。 本发明的口服自微乳化药物组合物通过注射显示与亲水药物相比的生物利用度,并且在储存期间是稳定的。 还提供了一种制备口服自微乳化药物组合物的方法。

    FREQUENCY SHIFT KEYING MODULATOR HAVING SIGMA-DELTA MODULATED PHASE ROTATOR
    4.
    发明申请
    FREQUENCY SHIFT KEYING MODULATOR HAVING SIGMA-DELTA MODULATED PHASE ROTATOR 有权
    具有SIGMA-DELTA调制相位旋转器的频移键控调制器

    公开(公告)号:US20080297269A1

    公开(公告)日:2008-12-04

    申请号:US12127798

    申请日:2008-05-27

    IPC分类号: H04L27/12

    CPC分类号: H04L27/12

    摘要: A frequency shift keying modulator having sigma-delta modulated phase rotator is disclosed, which includes a phase-locked loop for generating a voltage-controlled signal; a multi-phase generator for receiving the voltage-controlled signal and generating N phase-shift signals having same frequency according to the voltage-controlled signal, the N phase-shift signals having a same phase shift between the phase-shift signals adjacent to each other; a sigma-delta modulator for receiving transmission data and randomly outputting a modulation bit at a modulation clock according to the transmission data; and a phase rotator for receiving the N phase-shift signals and selectively outputting one of the N phase-shift signals and a frequency-divided signal according to the modulation bit, wherein the frequency of the frequency-divided signal is 1/(1+n/N) of the frequency of any one of the N phase-shift signals.

    摘要翻译: 公开了一种具有Σ-Δ调制相位旋转器的频移键控调制器,其包括用于产生电压控制信号的锁相环; 用于接收压控信号并根据压控信号产生具有相同频率的N个相移信号的多相发生器,N相移信号在与每个相邻相邻的相移信号之间具有相同的相移 其他; 一个Σ-Δ调制器,用于接收传输数据,并根据传输数据随机地输出一个调制时钟的调制位; 以及相位旋转器,用于接收N相移信号,并根据调制位选择性地输出N个相移信号和分频信号中的一个,其中分频信号的频率为1 /(1+ n / N)N个相移信号中的任何一个的频率。

    COMPOSITE OPTICAL FILM AND FLAT LIGHT SOURCE MODULE
    6.
    发明申请
    COMPOSITE OPTICAL FILM AND FLAT LIGHT SOURCE MODULE 审中-公开
    复合光学薄膜和平板光源模块

    公开(公告)号:US20100232137A1

    公开(公告)日:2010-09-16

    申请号:US12495823

    申请日:2009-07-01

    IPC分类号: G09F13/04 G02B27/10 F21V5/02

    摘要: A composite optical film including a base and an optical-field-modulation microstructure layer is provided. The base has a light incident surface and a light emitting surface, wherein the light incident surface and the light emitting surface are correspondingly disposed. The optical-field-modulation microstructure layer disposed on the light emitting surface has a first prism column set and a second prism column set, wherein the first prism column set has a plurality of first prism columns arranged in parallel and extended along a first direction, and the second prism column set has a plurality of second prism columns arranged in parallel and extended along a second direction. The first prism column set and the second prism column set are disposed across each other, and at least one of the first prism column set and the second prism column set has a smooth curve top.

    摘要翻译: 提供了包括基底和光场调制微结构层的复合光学膜。 基底具有光入射表面和发光表面,其中相应地设置光入射表面和发光表面。 设置在发光面上的光场调制微结构层具有第一棱柱列和第二棱镜列,其中,第一棱镜列具有平行布置并沿第一方向延伸的多个第一棱镜列, 并且所述第二棱镜列组具有平行布置并沿着第二方向延伸的多个第二棱镜列。 第一棱镜列组和第二棱镜列组彼此相对设置,并且第一棱镜列组和第二棱镜列组中的至少一个具有平滑的曲线顶部。

    Frequency shift keying modulator having sigma-delta modulated phase rotator
    7.
    发明授权
    Frequency shift keying modulator having sigma-delta modulated phase rotator 有权
    具有Σ-Δ调制相位旋转器的频移键控调制器

    公开(公告)号:US07667551B2

    公开(公告)日:2010-02-23

    申请号:US12127798

    申请日:2008-05-27

    IPC分类号: H03C3/00 H03K7/06 H04L27/12

    CPC分类号: H04L27/12

    摘要: A frequency shift keying modulator having sigma-delta modulated phase rotator is disclosed, which includes a phase-locked loop for generating a voltage-controlled signal; a multi-phase generator for receiving the voltage-controlled signal and generating N phase-shift signals having same frequency according to the voltage-controlled signal, the N phase-shift signals having a same phase shift between the phase-shift signals adjacent to each other; a sigma-delta modulator for receiving transmission data and randomly outputting a modulation bit at a modulation clock according to the transmission data; and a phase rotator for receiving the N phase-shift signals and selectively outputting one of the N phase-shift signals and a frequency-divided signal according to the modulation bit, wherein the frequency of the frequency-divided signal is 1 / ( 1 + n N ) of the frequency of any one of the N phase-shift signals.

    摘要翻译: 公开了一种具有Σ-Δ调制相位旋转器的频移键控调制器,其包括用于产生电压控制信号的锁相环; 用于接收压控信号并根据压控信号产生具有相同频率的N个相移信号的多相发生器,N相移信号在与每个相邻相邻的相移信号之间具有相同的相移 其他; 一个Σ-Δ调制器,用于接收传输数据,并根据传输数据随机地输出一个调制时钟的调制位; 以及相位旋转器,用于接收N相移信号,并根据调制位选择性地输出N个相移信号和分频信号中的一个,其中分频信号的频率为1 /(1 + n N)是N个相移信号中的任何一个的频率。

    Dual-lens hybrid diffractive/refractive imaging system
    8.
    发明授权
    Dual-lens hybrid diffractive/refractive imaging system 有权
    双透镜混合衍射/折射成像系统

    公开(公告)号:US06724532B1

    公开(公告)日:2004-04-20

    申请号:US10339335

    申请日:2003-01-10

    IPC分类号: G02B2744

    摘要: The present invention discloses a dual-lens hybrid diffractive/refractive imaging system comprising: a first lens including a concave surface and a convex surface; and the second lens including a convex surface and a concave surface. The concave surface of the first lens is an objective surface facing the object. The convex surface faces the convex surface of the second lens, while the concave surface of the second lens faces the charge-coupled device (CCD) through a filter. Any surface of the first lens and the second lens is spheric or aspheric. Moreover, the imaging system comprises at least one diffractive surface, referred to as a hybrid diffractive/refractive surface, formed on any surface of the two lenses. Therefore, aberration is eliminated and image quality is improved without increasing the number of lenses.

    摘要翻译: 本发明公开了一种双透镜混合衍射/折射成像系统,包括:第一透镜,包括凹面和凸面; 并且所述第二透镜包括凸面和凹面。 第一透镜的凹面是面向物体的物镜面。 凸面面对第二透镜的凸面,而第二透镜的凹面通过滤光器面对电荷耦合器件(CCD)。 第一透镜和第二透镜的任何表面是球形或​​非球面。 此外,成像系统包括形成在两个透镜的任何表面上的至少一个被称为混合衍射/折射表面的衍射表面。 因此,不增加透镜数量就能消除像差并提高图像质量。

    Apparatus for homogeneously distributing lights
    9.
    发明授权
    Apparatus for homogeneously distributing lights 有权
    用于均匀分布灯的装置

    公开(公告)号:US07125141B2

    公开(公告)日:2006-10-24

    申请号:US10782845

    申请日:2004-02-23

    IPC分类号: F21V5/00

    摘要: An apparatus for homogeneously distributing lights includes a light guide plate, an incidence microstructure and an emergence microstructure. The incidence microstructure is arranged on a surface of the light guide plate and opposite to a light source. The emergence microstructure is arranged on a surface of the light guide plate opposite to the incidence microstructure. The lights emitted by the light source pass through said apparatus thereby being homogenously distributed. Thus the manufacture costs are lowered, and the light source utilization ratio is increased.

    摘要翻译: 用于均匀分布光的装置包括导光板,入射微结构和出射微结构。 入射微结构布置在导光板的表面上并且与光源相对。 出射微结构布置在导光板的与入射微结构相对的表面上。 由光源发出的光通过所述装置从而均匀分布。 因此,制造成本降低,光源利用率提高。

    Multistage pump and method for assembling the pump
    10.
    发明授权
    Multistage pump and method for assembling the pump 有权
    多级泵和组装泵的方法

    公开(公告)号:US6123526A

    公开(公告)日:2000-09-26

    申请号:US156585

    申请日:1998-09-18

    IPC分类号: F04C23/00 F01C1/30

    CPC分类号: F04C23/001

    摘要: A multistage pump includes a shaft assembly and a housing and spacing plates. The shaft assembly completed by forming shafts and rotors integrally. The spacing plates defining a plurality of successive compression chambers, each chamber is delimited by two symmetrical spacing plates, there has a ring groove associated with the spacing plates, and having an elastic component placed. When the elastic component pressed by the housing, it became leakage and the clearance between the rotors and the spacing plates be easily controlled, by this way, the pump using parts are easy to manufacture, can be machined accurately and which enable highly accurate assembly to be achieved. As to the assembling method, which is characterized by mounting the high pressure end axial bearing seat and the high pressured end plate, then to control the clearance between the high pressure end plate of the bearing seat and the rotors. Furthermore, to install the spacing plates and the housing make the compression chamber formed.

    摘要翻译: 多级泵包括轴组件和壳体和间隔板。 轴组件通过一体形成轴和转子而完成。 间隔板限定多个连续的压缩室,每个室由两个对称的间隔板限定,其中有一个与间隔板相关的环槽,并具有放置的弹性部件。 当由壳体挤压的弹性部件变得泄漏时,转子和间隔板之间的间隙容易控制,这样,泵的使用部件易于制造,可以精确地加工,并且能够高精度地组装 实现。 关于组装方法,其特征在于安装高压端轴向座和高压端板,以控制轴承座的高压端板与转子之间的间隙。 此外,为了安装间隔板和壳体,形成压缩室。