公开(公告)号：US07924052B1

公开(公告)日：2011-04-12

申请号：US12361835

申请日：2009-01-29

申请人： Wenyi Feng ,  Jonathan Greene ,  Sinan Kaptanoglu

发明人： Wenyi Feng ,  Jonathan Greene ,  Sinan Kaptanoglu

IPC分类号： H01L25/00

CPC分类号： H03K19/17736

摘要： A cluster internal routing network for use in a programmable logic device with a cluster-based architecture employs a Clos network-based routing architecture. The routing architecture is a multi-stage blocking architecture, where the number of inputs to the first stage exceeds the number of outputs from the first stage.

摘要翻译： 在具有基于群集的架构的可编程逻辑设备中使用的集群内部路由网络采用基于Clos网络的路由架构。 路由架构是多级阻塞架构，其中第一级的输入数量超过了第一级的输出数量。

公开(公告)号：US07408383B1

公开(公告)日：2008-08-05

申请号：US11855974

申请日：2007-09-14

申请人： Wenyi Feng ,  Sinan Kaptanoglu

发明人： Wenyi Feng ,  Sinan Kaptanoglu

IPC分类号： H01L25/00 ,  H03K19/177

CPC分类号： H03K19/17736

摘要： An interconnect architecture for a programmable logic device comprises a plurality of interconnect routing lines. The data inputs of a plurality of first-level multiplexers are connected to the plurality of interconnect routing lines such that each interconnect routing line is connected to only one multiplexer. A plurality of second-level multiplexers are organized into multiplexer groups. Each of a plurality of lookup tables is associated with one of the multiplexer groups and has a plurality of lookup table inputs. Each lookup table input is coupled to the output of a different one of the second-level multiplexers in the one of the multiplexer groups with which it is associated. The data inputs of the second-level multiplexers are connected to the outputs of the first-level multiplexers such that each output of each first-level multiplexer is connected to an input of only one second-level multiplexer in each multiplexer group.

摘要翻译： 用于可编程逻辑器件的互连架构包括多个互连路由线。 多个第一级复用器的数据输入连接到多个互连路由线，使得每个互连路由线仅连接到一个多路复用器。 多个第二级多路复用器被组织成多路复用器组。 多个查找表中的每一个与多路复用器组中的一个相关联并且具有多个查找表输入。 每个查找表输入耦合到与其相关联的多路复合器组中的一个中的不同的一个二级多路复用器的输出。 第二级复用器的数据输入连接到第一级复用器的输出端，使得每个第一级多路复用器的每个输出端连接到每个复用器组中只有一个二级多路复用器的输入。

公开(公告)号：US07924053B1

公开(公告)日：2011-04-12

申请号：US12362844

申请日：2009-01-30

申请人： Sinan Kaptanoglu ,  Wenyi Feng

发明人： Sinan Kaptanoglu ,  Wenyi Feng

IPC分类号： H01L25/00

CPC分类号： H03K19/177

摘要： A logic cluster for a field programmable gate array integrated circuit device is disclosed. The cluster comprises a plurality of functional blocks and three levels of routing multiplexers. External signals enter the logic cluster primarily at the third level multiplexers with a few signals entering at the second level. Combinational outputs are fed back into the first and second level multiplexers while sequential outputs are fed back into the third level multiplexers. The logic function generators have permutable inputs with varying propagation delays. Routing signals between the first and second level multiplexers are grouped into speed classes and coupled to first level multiplexers associated with different logic function generators according to their speed class. Second and third level multiplexers are organized into groups such that routing signals between the second and third level multiplexers can be localized within the area occupied by the group. Groups are pitch matched to logic function generators to optimize and modularize area. Provision is made for global and local control of the sequential elements.

摘要翻译： 公开了一种用于现场可编程门阵列集成电路器件的逻辑集群。 集群包括多个功能块和三个级别的路由多路复用器。 外部信号主要进入第三级多路复用器的逻辑集群，其中几个信号进入第二级。 组合输出反馈到第一和第二电平复用器，而顺序输出反馈到第三级多路复用器。 逻辑函数发生器具有可变输入，具有不同的传播延迟。 第一和第二级多路复用器之间的路由信号被分组成速度等级并且根据其速度等级耦合到与不同逻辑函数发生器相关联的第一级复用器。 第二和第三级复用器被组织成组，使得第二和第三级多路复用器之间的路由信号可以被定位在该组占用的区域内。 组与逻辑功能发生器匹配，优化和模块化区域。 规定了全局和本地对顺序元素的控制。

公开(公告)号：US07545169B1

公开(公告)日：2009-06-09

申请号：US12173225

申请日：2008-07-15

申请人： Wenyi Feng ,  Sinan Kaptanoglu

发明人： Wenyi Feng ,  Sinan Kaptanoglu

IPC分类号： H01L25/00 ,  H03K19/177

CPC分类号： H03K19/17736

摘要： An interconnect architecture for a programmable logic device comprises a plurality of interconnect routing lines. The data inputs of a plurality of first-level multiplexers are connected to the plurality of interconnect routing lines such that each interconnect routing line is connected to only one multiplexer. A plurality of second-level multiplexers are organized into multiplexer groups. Each of a plurality of lookup tables is associated with one of the multiplexer groups and has a plurality of lookup table inputs. Each lookup table input is coupled to the output of a different one of the second-level multiplexers in the one of the multiplexer groups with which it is associated. The data inputs of the second-level multiplexers are connected to the outputs of the first-level multiplexers such that each output of each first-level multiplexer is connected to an input of only one second-level multiplexer in each multiplexer group.

摘要翻译： 用于可编程逻辑器件的互连架构包括多个互连路由线。 多个第一级复用器的数据输入连接到多个互连路由线，使得每个互连路由线仅连接到一个多路复用器。 多个第二级多路复用器被组织成多路复用器组。 多个查找表中的每一个与多路复用器组中的一个相关联并且具有多个查找表输入。 每个查找表输入耦合到与其相关联的多路复合器组中的一个中的不同的一个二级多路复用器的输出。 第二级复用器的数据输入连接到第一级复用器的输出，使得每个第一级多路复用器的每个输出连接到每个多路复用器组中仅一个第二级多路复用器的输入。

公开(公告)号：US08481903B2

公开(公告)日：2013-07-09

申请号：US13041194

申请日：2011-03-04

申请人： Alexander Triener ,  Erik Allegoren ,  Wenyi Feng ,  Dale Buermann ,  Erik Olson ,  James Osmus

发明人： Alexander Triener ,  Erik Allegoren ,  Wenyi Feng ,  Dale Buermann ,  Erik Olson ,  James Osmus

IPC分类号： G02B7/04

CPC分类号： C12Q1/6874 ,  C12Q1/6837 ,  G01N21/6428 ,  G01N21/645 ,  G01N21/6456

摘要： An optical system configured to detect optical signals during imaging sessions. The optical system includes an objective lens that has a collecting end that is positioned proximate to a sample and configured to receive optical signals therefrom. The optical system also includes a removable path compensator that is configured to be located at an imaging position between the collecting end of the objective lens and the sample. The path compensator adjusts an optical path of the light emissions when in the imaging position. Also, the optical system includes a transfer device that is configured to move the path compensator. The transfer device locates the path compensator at the imaging position for a first imaging session and removes the path compensator from the imaging position for a second imaging session.

摘要翻译： 一种配置成在成像会话期间检测光信号的光学系统。 光学系统包括物镜，该物镜具有位于样品附近并被配置为从其接收光信号的收集端。 光学系统还包括被配置为位于物镜的收集端和样品之间的成像位置处的可移除路径补偿器。 路径补偿器在成像位置调整光发射的光路。 此外，光学系统包括被配置为移动路径补偿器的传送装置。 传送装置将路径补偿器定位在用于第一成像会话的成像位置处，并从第二成像会话的成像位置移除路径补偿器。

公开(公告)号：US20120168644A1

公开(公告)日：2012-07-05

申请号：US13417474

申请日：2012-03-12

申请人： Wenyi Feng ,  Theofilos Kotseroglou ,  Mark Wang ,  Alexander Triener ,  Diping Che ,  Robert Kain

发明人： Wenyi Feng ,  Theofilos Kotseroglou ,  Mark Wang ,  Alexander Triener ,  Diping Che ,  Robert Kain

IPC分类号： G01N21/64

CPC分类号： G01N21/6456 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6458 ,  G01N2021/6421 ,  G02B21/0032 ,  G02B21/004

摘要： The invention provides imaging apparatus and methods useful for obtaining a high resolution image of a sample at rapid scan rates. A rectangular detector array having a horizontal dimension that is longer than the vertical dimension can be used along with imaging optics positioned to direct a rectangular image of a portion of a sample to the rectangular detector array. A scanning device can be configured to scan the sample in a scan-axis dimension, wherein the vertical dimension for the rectangular detector array and the shorter of the two rectangular dimensions for the image are in the scan-axis dimension, and wherein the vertical dimension for the rectangular detector array is short enough to achieve confocality in a single axis.

摘要翻译： 本发明提供了用于以快速扫描速率获得样品的高分辨率图像的成像装置和方法。 具有比垂直尺寸长的水平尺寸的矩形检测器阵列可以与定位成将样本的一部分的矩形图像引导到矩形检测器阵列的成像光学元件一起使用。 扫描装置可以被配置成以扫描轴尺寸扫描样本，其中矩形检测器阵列的垂直尺寸和图像的两个矩形尺寸中的较短的尺寸在扫描轴尺寸上，并且其中垂直尺寸 因为矩形检测器阵列足够短以在单个轴上实现共焦。

公开(公告)号：US20080117518A1

公开(公告)日：2008-05-22

申请号：US11602887

申请日：2006-11-21

申请人： Mark Wang ,  Wenyi Feng ,  Robert Kain

发明人： Mark Wang ,  Wenyi Feng ,  Robert Kain

IPC分类号： G02B27/10

CPC分类号： G01N21/6452 ,  G01N2021/6484 ,  G02B21/0032 ,  G02B21/0036

摘要： A line scanning arrangement for imaging microarrays includes a line illuminator that converts output from one or more lasers to a radiation line. The laser output passes through a single mode fiber and a module that converts the laser light to the radiation line. The line is confocally directed to sites on the microarray, and retrobeams returned from the sites are collected on an imaging detector. The microarray is moved in the imaging apparatus so as to progressively illuminate an array or matrix of sites for imaging.

摘要翻译： 用于成像微阵列的线扫描装置包括将一个或多个激光器的输出转换成辐射线的线照明器。 激光输出通过单模光纤和将激光转换成辐射线的模块。 该线与微阵列上的位点一致，并将从该位点返回的逆行器收集在成像检测器上。 微阵列在成像装置中移动，以逐渐照射用于成像的位点的阵列或矩阵。

公开(公告)号：US07329860B2

公开(公告)日：2008-02-12

申请号：US11286309

申请日：2005-11-23

申请人： Wenyi Feng ,  Theofilos Kotseroglou ,  Mark Wang ,  Alexander Triener ,  Diping Che ,  Robert Kain

发明人： Wenyi Feng ,  Theofilos Kotseroglou ,  Mark Wang ,  Alexander Triener ,  Diping Che ,  Robert Kain

IPC分类号： H01L27/00

CPC分类号： G01N21/6456 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6458 ,  G01N2021/6421 ,  G02B21/0032 ,  G02B21/004

摘要： The invention provides imaging apparatus and methods useful for obtaining a high resolution image of a sample at rapid scan rates. A rectangular detector array having a horizontal dimension that is longer than the vertical dimension can be used along with imaging optics positioned to direct a rectangular image of a portion of a sample to the rectangular detector array. A scanning device can be configured to scan the sample in a scan-axis dimension, wherein the vertical dimension for the rectangular detector array and the shorter of the two rectangular dimensions for the image are in the scan-axis dimension, and wherein the vertical dimension for the rectangular detector array is short enough to achieve confocality in a single axis.

摘要翻译： 本发明提供了用于以快速扫描速率获得样品的高分辨率图像的成像装置和方法。 具有比垂直尺寸长的水平尺寸的矩形检测器阵列可以与定位成将样本的一部分的矩形图像引导到矩形检测器阵列的成像光学元件一起使用。 扫描装置可以被配置成以扫描轴尺寸扫描样本，其中矩形检测器阵列的垂直尺寸和图像的两个矩形尺寸中的较短的尺寸在扫描轴尺寸上，并且其中垂直尺寸 因为矩形检测器阵列足够短以在单个轴上实现共焦。

公开(公告)号：US20120149585A1

公开(公告)日：2012-06-14

申请号：US13399820

申请日：2012-02-17

申请人： Wenyi Feng ,  Jason Bryant ,  Dale Buermann

发明人： Wenyi Feng ,  Jason Bryant ,  Dale Buermann

IPC分类号： C40B20/08 ,  C40B30/10

CPC分类号： C12Q1/6874 ,  C12Q1/6825 ,  C12Q1/6869 ,  G01N21/05 ,  G01N21/6458 ,  G01N2021/0346 ,  G01N2021/6419 ,  G01N2021/6421 ,  G02B21/0024 ,  G02B2207/113

摘要： A system and method for imaging biological samples on multiple surfaces of a support structure are disclosed. The support structure may be a flow cell through which a reagent fluid is allowed to flow and interact with the biological samples. Excitation radiation from at least one radiation source may be used to excite the biological samples on multiple surfaces. In this manner, fluorescent emission radiation may be generated from the biological samples and subsequently captured and detected by detection optics and at least one detector. The detected fluorescent emission radiation may then be used to generate image data. This imaging of multiple surfaces may be accomplished either sequentially or simultaneously. In addition, the techniques of the present invention may be used with any type of imaging system. For instance, both epifluorescent and total internal reflection methods may benefit from the techniques of the present invention.

摘要翻译： 公开了用于在支撑结构的多个表面上成像生物样品的系统和方法。 支撑结构可以是允许试剂流体通过其流动并与生物样品相互作用的流动池。 来自至少一个辐射源的激发辐射可用于在多个表面上激发生物样品。 以这种方式，可以从生物样品产生荧光发射辐射，随后由检测光学器件和至少一个检测器捕获和检测。 然后可以使用检测到的荧光发射辐射来产生图像数据。 多个表面的这种成像可以顺序地或同时地完成。 此外，本发明的技术可以与任何类型的成像系统一起使用。 例如，荧光和全内反射方法都可以受益于本发明的技术。

公开(公告)号：US20110204212A1

公开(公告)日：2011-08-25

申请号：US13099062

申请日：2011-05-02

申请人： Wenyi Feng ,  Theofilos Kotseroglou ,  Mark Wang ,  Alexander Triener ,  Diping Che ,  Robert Kain

发明人： Wenyi Feng ,  Theofilos Kotseroglou ,  Mark Wang ,  Alexander Triener ,  Diping Che ,  Robert Kain

IPC分类号： G01J1/58 ,  G01J1/42

CPC分类号： G01N21/6456 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6458 ,  G01N2021/6421 ,  G02B21/0032 ,  G02B21/004

摘要： The invention provides imaging apparatus and methods useful for obtaining a high resolution image of a sample at rapid scan rates. A rectangular detector array having a horizontal dimension that is longer than the vertical dimension can be used along with imaging optics positioned to direct a rectangular image of a portion of a sample to the rectangular detector array. A scanning device can be configured to scan the sample in a scan-axis dimension, wherein the vertical dimension for the rectangular detector array and the shorter of the two rectangular dimensions for the image are in the scan-axis dimension, and wherein the vertical dimension for the rectangular detector array is short enough to achieve confocality in a single axis.

摘要翻译： 本发明提供了用于以快速扫描速率获得样品的高分辨率图像的成像装置和方法。 具有比垂直尺寸长的水平尺寸的矩形检测器阵列可以与定位成将样本的一部分的矩形图像引导到矩形检测器阵列的成像光学元件一起使用。 扫描装置可以被配置成以扫描轴尺寸扫描样本，其中矩形检测器阵列的垂直尺寸和图像的两个矩形尺寸中的较短的尺寸在扫描轴尺寸上，并且其中垂直尺寸 因为矩形检测器阵列足够短以在单个轴上实现共焦。