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公开(公告)号：US09670464B2
公开(公告)日：2017-06-06
申请号：US14923321
申请日：2015-10-26
Applicant: Whitehead Institute for Biomedical Research
Inventor： Rudolf Jaenisch , Konrad Hochedlinger
IPC: C12N5/00 , C12N5/074 , A01K67/027 , C07K14/47 , C12N15/85 , C12N15/877
CPC classification number: C12N5/0696 , A01K67/0273 , A01K67/0275 , A01K2217/05 , A01K2227/105 , C07K14/4702 , C12N15/85 , C12N15/8509 , C12N15/8775 , C12N2501/602 , C12N2501/603 , C12N2501/605 , C12N2506/1307 , C12N2510/00 , C12N2830/003 , C12N2830/006
Abstract: The invention provides methods for reprogramming somatic cells to generate multipotent or pluripotent cells. Such methods are useful for a variety of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a less differentiated state.
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公开(公告)号：US11987815B2
公开(公告)日：2024-05-21
申请号：US16665821
申请日：2019-10-28
Applicant: Whitehead Institute for Biomedical Research
Inventor： Rudolf Jaenisch , Konrad Hochedlinger
IPC: C12N5/074 , C12N15/85 , A01K67/0273 , A01K67/0275 , C07K14/47 , C12N15/877
CPC classification number: C12N5/0696 , C12N15/85 , A01K67/0273 , A01K67/0275 , A01K2217/05 , A01K2227/105 , C07K14/4702 , C12N15/8509 , C12N15/8775 , C12N2501/602 , C12N2501/603 , C12N2501/605 , C12N2506/1307 , C12N2510/00 , C12N2830/003 , C12N2830/006
Abstract: The invention provides methods for reprogramming somatic cells to generate multipotent or pluripotent cells. Such methods are useful for a variety of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a less differentiated state.
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公开(公告)号：US11655459B2
公开(公告)日：2023-05-23
申请号：US17898360
申请日：2022-08-29
Applicant: Whitehead Institute for Biomedical Research
Inventor： Rudolf Jaenisch , Konrad Hochedlinger
IPC: C12N15/85 , C12N5/074 , A01K67/027 , C07K14/47 , C12N15/877
CPC classification number: C12N5/0696 , C12N15/85 , A01K67/0273 , A01K67/0275 , A01K2217/05 , A01K2227/105 , C07K14/4702 , C12N15/8509 , C12N15/8775 , C12N2501/602 , C12N2501/603 , C12N2501/605 , C12N2506/1307 , C12N2510/00 , C12N2830/003 , C12N2830/006
Abstract: The invention provides methods for reprogramming somatic cells to generate multipotent or pluripotent cells. Such methods are useful for a variety of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a less differentiated state.
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公开(公告)号：US10017744B2
公开(公告)日：2018-07-10
申请号：US15588062
申请日：2017-05-05
Applicant: Whitehead Institute for Biomedical Research
Inventor： Rudolf Jaenisch , Konrad Hochedlinger
CPC classification number: C12N5/0696 , A01K67/0273 , A01K67/0275 , A01K2217/05 , A01K2227/105 , C07K14/4702 , C12N15/85 , C12N15/8509 , C12N15/8775 , C12N2501/602 , C12N2501/603 , C12N2501/605 , C12N2506/1307 , C12N2510/00 , C12N2830/003 , C12N2830/006
Abstract: The invention provides methods for reprogramming somatic cells to generate multipotent or pluripotent cells. Such methods are useful for a variety of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a less differentiated state.
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公开(公告)号：US08932856B2
公开(公告)日：2015-01-13
申请号：US13646444
申请日：2012-10-05
Applicant: Whitehead Institute for Biomedical Research
Inventor： Rudolf Jaenisch , Konrad Hochedlinger
IPC: C12N5/00 , C12N15/85 , A01K67/027 , C07K14/47 , C12N15/877 , C12N5/074
CPC classification number: C12N5/0696 , A01K67/0273 , A01K67/0275 , A01K2217/05 , A01K2227/105 , C07K14/4702 , C12N15/85 , C12N15/8509 , C12N15/8775 , C12N2501/602 , C12N2501/603 , C12N2501/605 , C12N2506/1307 , C12N2510/00 , C12N2830/003 , C12N2830/006
Abstract: The invention provides methods for reprogramming somatic cells to generate multipotent or pluripotent cells. Such methods are useful for a variety of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a less differentiated state.
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Patent Agency Ranking
公开(公告)号：US20130102074A1
公开(公告)日：2013-04-25
申请号：US13646420
申请日：2012-10-05
Applicant: Whitehead Institute for Biomedical Research
Inventor： Rudolf Jaenisch , Konrad Hochedlinger
IPC: C12N5/071
CPC classification number: C12N5/0696 , A01K67/0273 , A01K67/0275 , A01K2217/05 , A01K2227/105 , C07K14/4702 , C12N15/85 , C12N15/8509 , C12N15/8775 , C12N2501/602 , C12N2501/603 , C12N2501/605 , C12N2506/1307 , C12N2510/00 , C12N2830/003 , C12N2830/006
Abstract: The invention provides methods for reprogramming somatic cells to generate multipotent or pluripotent cells. Such methods are useful for a variety of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a less differentiated state.
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公开(公告)号：US20220403344A1
公开(公告)日：2022-12-22
申请号：US17898360
申请日：2022-08-29
Applicant: Whitehead Institute for Biomedical Research
Inventor： Rudolf Jaenisch , Konrad Hochedlinger
Abstract: The invention provides methods for reprogramming somatic cells to generate multipotent or pluripotent cells. Such methods are useful for a variety of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a less differentiated state.
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公开(公告)号：US08951797B2
公开(公告)日：2015-02-10
申请号：US13646411
申请日：2012-10-05
Applicant: Whitehead Institute for Biomedical Research
Inventor： Rudolf Jaenisch , Konrad Hochedlinger
IPC: C12N5/00 , C12N15/85 , A01K67/027 , C07K14/47 , C12N15/877 , C12N5/074
CPC classification number: C12N5/0696 , A01K67/0273 , A01K67/0275 , A01K2217/05 , A01K2227/105 , C07K14/4702 , C12N15/85 , C12N15/8509 , C12N15/8775 , C12N2501/602 , C12N2501/603 , C12N2501/605 , C12N2506/1307 , C12N2510/00 , C12N2830/003 , C12N2830/006
Abstract: The invention provides methods for reprogramming somatic cells to generate multipotent or pluripotent cells. Such methods are useful for a variety of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a less differentiated state.
Abstract translation: 本发明提供了重编程体细胞产生多潜能或多潜能细胞的方法。 这些方法可用于各种目的，包括治疗或预防个体的医疗状况。 本发明进一步提供了用于鉴定将体细胞重新编程为较差分化状态的药剂的方法。
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公开(公告)号：US08927279B2
公开(公告)日：2015-01-06
申请号：US13646420
申请日：2012-10-05
Applicant: Whitehead Institute for Biomedical Research
Inventor： Rudolf Jaenisch , Konrad Hochedlinger
IPC: C12N5/00 , C12N5/02 , C12N15/85 , A01K67/027 , C07K14/47 , C12N15/877 , C12N5/074
CPC classification number: C12N5/0696 , A01K67/0273 , A01K67/0275 , A01K2217/05 , A01K2227/105 , C07K14/4702 , C12N15/85 , C12N15/8509 , C12N15/8775 , C12N2501/602 , C12N2501/603 , C12N2501/605 , C12N2506/1307 , C12N2510/00 , C12N2830/003 , C12N2830/006
Abstract: The invention provides methods for reprogramming somatic cells to generate multipotent or pluripotent cells. Such methods are useful for a variety of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a less differentiated state.
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公开(公告)号：US20130109090A1
公开(公告)日：2013-05-02
申请号：US13646430
申请日：2012-10-05
Applicant: Whitehead Institute for Biomedical Research
Inventor： Rudolf Jaenisch , Konrad Hochedlinger
IPC: C12N15/85
CPC classification number: C12N5/0696 , A01K67/0273 , A01K67/0275 , A01K2217/05 , A01K2227/105 , C07K14/4702 , C12N15/85 , C12N15/8509 , C12N15/8775 , C12N2501/602 , C12N2501/603 , C12N2501/605 , C12N2506/1307 , C12N2510/00 , C12N2830/003 , C12N2830/006
Abstract: The invention provides methods for reprogramming somatic cells to generate multipotent or pluripotent cells. Such methods are useful for a variety of purposes, including treating or preventing a medical condition in an individual. The invention further provides methods for identifying an agent that reprograms somatic cells to a less differentiated state.
Abstract translation: 本发明提供了重编程体细胞产生多潜能或多潜能细胞的方法。 这些方法可用于各种目的，包括治疗或预防个体的医疗状况。 本发明进一步提供了用于鉴定将体细胞重新编程为较差分化状态的药剂的方法。
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