-
1.发明申请公开(公告)号：US20070249619A1
公开(公告)日：2007-10-25
申请号：US11572948
申请日：2005-07-27
申请人： William Brown , Andrew Griffin , Thomas Hudzik , Carla Maciag , Gennady Smagin , Christopher Walpole
发明人： William Brown , Andrew Griffin , Thomas Hudzik , Carla Maciag , Gennady Smagin , Christopher Walpole
IPC分类号： A61K31/50 , A61P25/00 , C07D241/04
CPC分类号： C07D295/145 , C07D295/155
摘要： Compounds of general formula: as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain, depression and anxiety.
摘要翻译： 制备通式的化合物及其盐，对映异构体和包括该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛，抑郁和焦虑。
-
2.发明申请Diarylmethyl piperazine derivatives, preparations thereof and uses thereof 审中-公开二芳基甲基哌嗪衍生物，其制备方法及用途公开(公告)号：US20060030569A1
公开(公告)日：2006-02-09
申请号：US11243623
申请日：2005-10-05
申请人： William Brown , Andrew Griffin , Thomas Hudzik , Carla Maciag , Gennady Smagin , Christopher Walpole
发明人： William Brown , Andrew Griffin , Thomas Hudzik , Carla Maciag , Gennady Smagin , Christopher Walpole
IPC分类号： A61K31/495 , C07D241/04
CPC分类号： C07D295/145 , C07D295/155
摘要： Compounds of general formula: as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain, depression and anxiety.
摘要翻译： 制备通式的化合物及其盐，对映异构体和包括该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛，抑郁和焦虑。
-
3.发明申请公开(公告)号：US20100168130A1
公开(公告)日：2010-07-01
申请号：US12644309
申请日：2009-12-22
申请人： William Brown , Andrew Griffin , Thomas Hudzik , Carla Maciag , Gennady Smagin , Christopher Walpole
发明人： William Brown , Andrew Griffin , Thomas Hudzik , Carla Maciag , Gennady Smagin , Christopher Walpole
IPC分类号： A61K31/495 , C07D241/04 , A61P25/22 , A61P25/24 , A61P25/16
CPC分类号： C07D295/155
摘要： Compounds of general formula: as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain, depression and anxiety.
摘要翻译： 制备通式的化合物及其盐，对映异构体和包括该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛，抑郁和焦虑。
-
4.发明申请公开(公告)号：US20120149717A1
公开(公告)日：2012-06-14
申请号：US13401139
申请日：2012-02-21
申请人： William Brown , Andrew Griffin , Thomas Hudzik , Carla Maciag , Gennady Smagin , Christopher Walpole
发明人： William Brown , Andrew Griffin , Thomas Hudzik , Carla Maciag , Gennady Smagin , Christopher Walpole
IPC分类号： A61K31/495 , A61P25/22 , C07D295/155
CPC分类号： C07D295/155
摘要： Compounds of general formula: as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain, depression and anxiety.
摘要翻译： 制备通式的化合物及其盐，对映异构体和包括该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛，抑郁和焦虑。
-
5.发明授权公开(公告)号：US08129393B2
公开(公告)日：2012-03-06
申请号：US12644309
申请日：2009-12-22
申请人： William Brown , Andrew Griffin , Thomas Hudzik , Carla Maciag , Gennady Smagin , Christopher Walpole
发明人： William Brown , Andrew Griffin , Thomas Hudzik , Carla Maciag , Gennady Smagin , Christopher Walpole
IPC分类号： A61K31/497 , C07D241/04
CPC分类号： C07D295/155
摘要： Compounds of general formula: as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain, depression and anxiety.
摘要翻译： 制备通式的化合物及其盐，对映异构体和包括该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛，抑郁和焦虑。
-
6.发明申请4-{'3-(Sulfonylamino) phenyl!'1-(cyclymethyl) piperidin-4-ylidene! methyl}benazmide derivativess as delta opioid receptor ligands for the treatment of pain, anxiety and functional gastrointestinal disorder 审中-公开4 - {'3-（磺酰基氨基）苯基''1-（环甲基）哌啶-4-亚基 甲基} benazmide衍生为δ阿片受体配体，用于治疗疼痛，焦虑和功能性胃肠道疾病公开(公告)号：US20060148850A1
公开(公告)日：2006-07-06
申请号：US10541664
申请日：2004-01-13
IPC分类号： A61K31/4545 , A61K31/454 , C07D211/68
CPC分类号： C07D401/06 , C07D211/70 , C07D405/06 , C07D409/06 , C07D417/06
摘要： Compounds of general formula: (I) wherein R1, R2, R3, R4 and R5 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译： 通式（I）的化合物，其中R 1，R 2，R 3，R 4和R 4，R 说明书中定义的，以及其盐，对映异构体和包含该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛。
-
7.发明授权4(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain or gastrointestinal disorders 失效4（苯基 - 哌嗪基 - 甲基）苯甲酰胺衍生物及其用于治疗疼痛或胃肠道疾病的用途公开(公告)号：US07960389B2
公开(公告)日：2011-06-14
申请号：US11774935
申请日：2007-07-09
申请人： William Brown , Andrew Griffin , Paul Jones , Daniel Page , Niklas Plobeck , Christopher Walpole
发明人： William Brown , Andrew Griffin , Paul Jones , Daniel Page , Niklas Plobeck , Christopher Walpole
IPC分类号： A61K31/4965 , A61P25/22 , C07D295/03
CPC分类号： C07D213/38 , C07D215/12 , C07D233/64 , C07D277/28 , C07D295/155 , C07D307/52 , C07D333/20
摘要： Compounds of general formula: wherein R1, R2 and R3 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译： 制备通式如下的化合物：其中R 1，R 2和R 3如本说明书中所定义，以及其盐，对映异构体和包含该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛。
-
8.发明申请4(Phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain or gastrointestinal disorders 失效4（苯基 - 哌嗪基 - 甲基）苯甲酰胺衍生物及其用于治疗疼痛或胃肠道疾病的用途公开(公告)号：US20060122193A1
公开(公告)日：2006-06-08
申请号：US10533654
申请日：2003-11-05
申请人： William Brown , Andrew Griffin , Paul Jones , Daniel Page , Niklas Plobeck , Christopher Walpole
发明人： William Brown , Andrew Griffin , Paul Jones , Daniel Page , Niklas Plobeck , Christopher Walpole
IPC分类号： A61K31/495 , C07D241/04
CPC分类号： C07D213/38 , C07D215/12 , C07D233/64 , C07D277/28 , C07D295/155 , C07D307/52 , C07D333/20
摘要： Compounds of general formula (1) wherein R1, R2 and R3 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译： 其中R 1，R 2和R 3的通式（1）的化合物如说明书中所定义，以及盐，对映异构体 并且制备包含该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛。
-
9.发明申请Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof 审中-公开二芳基亚甲基哌啶衍生物，其制备方法及用途公开(公告)号：US20060116399A1
公开(公告)日：2006-06-01
申请号：US10541656
申请日：2004-01-13
IPC分类号： A61K31/4545 , A61K31/454 , C07D403/02 , C07D401/02 , C07D413/02 , C07D417/02
CPC分类号： C07D211/70 , C07D405/06 , C07D409/06 , C07D417/06
摘要： Compounds of general formula: wherein R1, R2, R3, R4, and R5 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译： 下列通式的化合物：其中R 1，R 2，R 3，R 4和R 4 > 5 如本说明书中所定义，以及其盐，对映体和包含该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛。
-
10.发明申请Diarylmethylidene Piperidine Derivatives, Preparations Thereof and Uses Thereof 审中-公开二芳基亚甲基哌啶衍生物，其制备及其用途公开(公告)号：US20080262038A1
公开(公告)日：2008-10-23
申请号：US10596853
申请日：2005-01-05
IPC分类号： A61K31/4545 , C07D211/00 , C07D401/02 , A61P25/22 , A61P25/00 , A61K31/4535 , A61K31/445
CPC分类号： C07D417/06 , C07D211/70 , C07D401/06
摘要： Compounds of Formula: wherein R1, R2, and R3 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.
摘要翻译： 其中R 1，R 2和R 3的化合物如说明书中所定义，以及其盐，对映体和 制备包含该化合物的药物组合物。 它们可用于治疗，特别是治疗疼痛。
-
-
-
-
-
-
-
-
-
搜索结果
47 条记录 (耗时 0.031 秒)
