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1.发明授权公开(公告)号：US06355030B1
公开(公告)日：2002-03-12
申请号：US09161079
申请日：1998-09-25
IPC分类号： A61B1804
CPC分类号： A61B18/08 , A61B90/30 , A61B2017/00084 , A61B2017/00243 , A61B2018/046 , A61F2/2412 , A61F2/2427 , A61F2/2445 , A61F2/2463 , A61F2250/0059
摘要： The present invention is methods and devices for improving valve function in a heart. Particularly a device of the present invention comprises a an elongate member having a distal end and a proximal end, a thermal heating member fixed to the distal end of the elongate member, wherein the thermal heating member includes at least one thermal heating element adapted to supply thermal energy to a heart valve structure, and an energy source in communication with the thermal heating element. In use, a thermal heating device of the present invention is inserted into working space proximate the valve to be treated and is used to selectively contract the collagen fibers of the valve structure treated so as to improve the performance and functioning of the valve. Devices are disclosed suitable for use with a variety of access procedures on both beating and non-beating hearts, including: a minimally invasive surgical procedure, a sternotomy, a thoracotomy, an endovascular procedure, and endoscopic procedure, or a percutaneous procedure. Methods and devices are disclosed which are suitable for treatment of a chordae, leaflet, or annulus, as well as devices and methods for the replacement of heart valve with prosthetic valves.
摘要翻译： 本发明是用于改善心脏中的瓣膜功能的方法和装置。 特别地，本发明的装置包括具有远端和近端的细长构件，固定到细长构件的远端的热加热构件，其中热加热构件包括至少一个适于供应的热加热元件 与心脏瓣膜结构的热能，以及与热加热元件连通的能量源。 在使用中，将本发明的热加热装置插入靠近待处理的阀的工作空间中，并用于选择性地收缩被处理的阀结构的胶原纤维，以改善阀的性能和功能。 公开的装置被公开适用于跳动和非跳动心脏上的各种进入程序，包括：微创外科手术，胸骨切开术，开胸手术，血管内手术和内窥镜手术或经皮手术。 公开了适用于治疗腱索，小叶或环的方法和装置，以及用人造瓣膜置换心脏瓣膜的装置和方法。
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公开(公告)号：US06636758B2
公开(公告)日：2003-10-21
申请号：US09847769
申请日：2001-05-01
IPC分类号： A61B600
CPC分类号： A61B17/12113 , A61B6/12 , A61B17/12022 , A61B17/1214 , A61B90/39 , A61B2017/22042 , A61B2090/061 , A61B2090/063 , A61M25/0108
摘要： This is a medical device, specifically used in surgery. It is a wire having distal radio-opaque markers and may be used, for instance, in endovascular procedures as a marker wire for estimating or referencing the structural attributes of internal physical features. In addition, the inventive marker wire may be used as a guide wire for a catheter used in endovascular procedures.
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公开(公告)号：US20130079858A1
公开(公告)日：2013-03-28
申请号：US13247044
申请日：2011-09-28
IPC分类号： A61F7/12
CPC分类号： A61F7/12 , A61F7/123 , A61F2007/0054 , A61F2007/0056 , A61F2007/0096 , A61F2007/126
摘要： A transatrial intravascular temperature management catheter has a lower heat exchange segment positionable in the inferior vena cava and an upper heat exchange segment positionable in the superior vane cava, with a connecting segment lying between the two and positionable in the right atrium. A temperature sensor on the distal tip of the upper heat exchange segment provides accurate core body temperature signals for feedback purposes since the blood flowing past the sensor has not yet reached the heat exchange segment.
摘要翻译： 经腔内血管内温度管理导管具有位于下腔静脉中的较低热交换段和位于上叶片卡瓦中的上部热交换段，连接段位于两者之间并且可定位在右心房中。 上部热交换区段的远端顶部的温度传感器提供准确的核心体温信号用于反馈目的，因为流过传感器的血液尚未到达热交换区段。
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公开(公告)号：US09314370B2
公开(公告)日：2016-04-19
申请号：US13247122
申请日：2011-09-28
CPC分类号： A61F7/12 , A61F2007/0054 , A61F2007/126
摘要： A patient temperature control catheter includes working fluid supply and return lumens through which working fluid circulates to exchange heat with a patient in whom the catheter is positioned. At least one lumen is defined by plural coils axially spaced from each other. At least a first coil is a large coil that inflates with working fluid to seat against a wall of a blood vessel in which the catheter is positioned, with blood flowing through the coil so as not to block blood flow in the vessel.
摘要翻译： 患者温度控制导管包括工作流体供应和返回内腔，工作流体通过该腔流动，与导管所位于的患者交换热量。 至少一个腔由彼此轴向间隔开的多个线圈限定。 至少第一线圈是大的线圈，其使用工作流体进行充气以抵靠导管定位的血管的壁，血液流过线圈，以便不阻止血管中的血液流动。
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公开(公告)号：US09259348B2
公开(公告)日：2016-02-16
申请号：US13247044
申请日：2011-09-28
CPC分类号： A61F7/12 , A61F7/123 , A61F2007/0054 , A61F2007/0056 , A61F2007/0096 , A61F2007/126
摘要： A transatrial intravascular temperature management catheter has a lower heat exchange segment positionable in the inferior vena cava and an upper heat exchange segment positionable in the superior vane cava, with a connecting segment lying between the two and positionable in the right atrium. A temperature sensor on the distal tip of the upper heat exchange segment provides accurate core body temperature signals for feedback purposes since the blood flowing past the sensor has not yet reached the heat exchange segment.
摘要翻译： 经腔内血管内温度管理导管具有位于下腔静脉中的较低热交换段和位于上叶片卡瓦中的上部热交换段，连接段位于两者之间并且可定位在右心房中。 上部热交换区段的远端顶部的温度传感器提供准确的核心体温信号用于反馈目的，因为流过传感器的血液尚未到达热交换区段。
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公开(公告)号：US20130079856A1
公开(公告)日：2013-03-28
申请号：US13247122
申请日：2011-09-28
IPC分类号： A61F7/12
CPC分类号： A61F7/12 , A61F2007/0054 , A61F2007/126
摘要： A patient temperature control catheter includes working fluid supply and return lumens through which working fluid circulates to exchange heat with a patient in whom the catheter is positioned. At least one lumen is defined by plural coils axially spaced from each other. At least a first coil is a large coil that inflates with working fluid to seat against a wall of a blood vessel in which the catheter is positioned, with blood flowing through the coil so as not to block blood flow in the vessel.
摘要翻译： 患者温度控制导管包括工作流体供应和返回内腔，工作流体通过该腔流动，与导管所位于的患者交换热量。 至少一个腔由彼此轴向间隔开的多个线圈限定。 至少第一线圈是大的线圈，其使用工作流体进行充气以抵靠导管定位的血管的壁，血液流过线圈，以便不阻止血管中的血液流动。
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7.发明授权公开(公告)号：US06953465B2
公开(公告)日：2005-10-11
申请号：US10106483
申请日：2002-03-25
CPC分类号： A61B17/1219 , A61B17/12022 , A61B17/12113 , A61B17/12186 , A61B50/30 , A61B2017/1205
摘要： This is directed to containers and methods for holding and delivering vaso-occluding materials such as hydrogel particles and filaments. The vaso-occlusive materials may be held in the container in a hydrated or unhydrated state. The container includes a fluid ingress port and a fluid egress port that are respectively fluidly connectable with a fluid source and a delivery catheter. The container further includes at least one chamber or passageway extending therebetween. The passageway may be straight, curved, spiral, helical, narrow or otherwise shaped. The chamber may also have sections of varying cross section such as a ramped section. The shapes of the passageways of the container help organize ejection of the vaso-occluding materials minimizing contamination and clumping. Methods for holding and introducing the materials are also provided.
摘要翻译： 这涉及用于保持和输送血管阻塞材料如水凝胶颗粒和细丝的容器和方法。 血管闭塞性材料可以以水合或非水合状态保持在容器中。 容器包括流体入口和流体出口，其分别可流体地与流体源和递送导管连接。 容器还包括在其间延伸的至少一个室或通道。 通道可以是直的，弯曲的，螺旋形的，螺旋形的，狭窄的或其他形状的。 腔室还可以具有变化的横截面的部分，例如斜坡部分。 容器通道的形状有助于组织排出阻塞物质，以最大限度地减少污染和结块。 还提供了保存和引入材料的方法。
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公开(公告)号：US10045881B2
公开(公告)日：2018-08-14
申请号：US13247073
申请日：2011-09-28
CPC分类号： A61F7/12 , A61B2017/00867 , A61F2007/126
摘要： A catheter includes a working fluid supply path communicating with a source of working fluid. The catheter also includes a working fluid return path communicating with the working fluid supply path to return working fluid from the supply path to the source of working fluid. At least one of the paths is contained in a distal heat exchange region of the catheter, where the distal heat exchange region includes first and second helical paths and is made of a shape memory material.
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公开(公告)号：US20130079855A1
公开(公告)日：2013-03-28
申请号：US13247073
申请日：2011-09-28
IPC分类号： A61F7/12
CPC分类号： A61F7/12 , A61B2017/00867 , A61F2007/126
摘要： A catheter includes a working fluid supply path communicating with a source of working fluid. The catheter also includes a working fluid return path communicating with the working fluid supply path to return working fluid from the supply path to the source of working fluid. At least one of the paths is contained in a distal heat exchange region of the catheter, where the distal heat exchange region includes first and second helical paths and is made of a shape memory material.
摘要翻译： 导管包括与工作流体源连通的工作流体供应路径。 导管还包括与工作流体供应路径连通以将工作流体从供给路径返回到工作流体源的工作流体返回路径。 至少一条路径包含在导管的远端热交换区域中，其中远侧热交换区域包括第一和第二螺旋路径并且由形状记忆材料制成。
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公开(公告)号：US20160058613A1
公开(公告)日：2016-03-03
申请号：US14783912
申请日：2014-04-08
IPC分类号： A61F7/12 , A61B5/00 , A61B5/0205 , A61F7/10 , A61B5/0488
摘要： A method of reducing the likelihood of shivering comprises monitoring at least one physiological characteristic in a human or animal subject to detect preshivering and acting to reduce the likelihood of shivering when preshivering is detected.
摘要翻译： 减少发抖的可能性的方法包括监测人或动物对象中的至少一种生理特征以检测预发作用，并且用于当检测到预发作时降低发抖的可能性。
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