公开(公告)号：US20200150106A1

公开(公告)日：2020-05-14

申请号：US16745182

申请日：2020-01-16

Applicant: Wisconsin Alumni Research Foundation

Inventor： Michael R. Sussman ,  J. Leon Shohet ,  Faraz A. Choudhury ,  Joshua M. Blatz ,  Benjamin B. Minkoff ,  Daniel I. Benjamin

IPC: G01N33/50 ,  H05H1/24 ,  G01N33/68 ,  G01N33/487 ,  G01N1/28 ,  C12Q1/6876 ,  B01J19/08

Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.

公开(公告)号：US20230061431A1

公开(公告)日：2023-03-02

申请号：US17716499

申请日：2022-04-08

Applicant: Wisconsin Alumni Research Foundation

Inventor： Michael R. Sussman ,  J. Leon Shohet ,  Faraz A. Choudhury ,  Joshua M. Blatz ,  Benjamin B. Minkoff ,  Daniel I. Benjamin

IPC: G01N33/50 ,  B01J19/08 ,  C12Q1/6876 ,  G01N1/28 ,  G01N33/487 ,  G01N33/68 ,  H05H1/24

Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.

公开(公告)号：US11300562B2

公开(公告)日：2022-04-12

申请号：US16745182

申请日：2020-01-16

Applicant: Wisconsin Alumni Research Foundation

Inventor： Michael R. Sussman ,  J. Leon Shohet ,  Faraz A. Choudhury ,  Joshua M. Blatz ,  Benjamin B. Minkoff ,  Daniel I. Benjamin

IPC: B01J19/08 ,  G01N33/50 ,  C12Q1/6876 ,  G01N1/28 ,  G01N33/487 ,  G01N33/68 ,  H05H1/24 ,  H01J49/00

Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.

公开(公告)号：US10571460B2

公开(公告)日：2020-02-25

申请号：US15600352

申请日：2017-05-19

Applicant: Wisconsin Alumni Research Foundation

Inventor： Michael R. Sussman ,  J. Leon Shohet ,  Faraz A. Choudhury ,  Joshua M. Blatz ,  Benjamin B. Minkoff ,  Daniel I. Benjamin

IPC: H05H1/24 ,  G01N33/50 ,  B01J19/08 ,  C12Q1/6876 ,  G01N1/28 ,  G01N33/487 ,  G01N33/68 ,  H01J49/00

Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.

公开(公告)号：US20170336390A1

公开(公告)日：2017-11-23

申请号：US15600352

申请日：2017-05-19

Applicant: Wisconsin Alumni Research Foundation

Inventor： Michael R. Sussman ,  J. Leon Shohet ,  Faraz A. Choudhury ,  Joshua M. Blatz ,  Benjamin B. Minkoff ,  Daniel I. Benjamin

IPC: G01N33/50 ,  G01N33/68 ,  G01N1/28 ,  G01N33/487 ,  B01J19/08 ,  H05H1/24 ,  C12Q1/68 ,  H01J49/00

CPC classification number: G01N33/50 ,  B01J19/088 ,  B01J2219/0809 ,  B01J2219/0894 ,  C12Q1/6876 ,  G01N1/28 ,  G01N33/487 ,  G01N33/6848 ,  G01N2333/765 ,  G01N2333/90216 ,  G01N2333/91215 ,  G01N2440/00 ,  H01J49/0031 ,  H05H1/24

Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.