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公开(公告)号:US11300562B2
公开(公告)日:2022-04-12
申请号:US16745182
申请日:2020-01-16
Applicant: Wisconsin Alumni Research Foundation
Inventor: Michael R. Sussman , J. Leon Shohet , Faraz A. Choudhury , Joshua M. Blatz , Benjamin B. Minkoff , Daniel I. Benjamin
IPC: B01J19/08 , G01N33/50 , C12Q1/6876 , G01N1/28 , G01N33/487 , G01N33/68 , H05H1/24 , H01J49/00
Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
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公开(公告)号:US12247920B2
公开(公告)日:2025-03-11
申请号:US18114883
申请日:2023-02-27
Applicant: Wisconsin Alumni Research Foundation
Inventor: J. Leon Shohet , Michael R. Sussman , Faraz A. Choudhury , Benjamin B. Minkoff , Grzegorz Sabat , Joshua M. Blatz
Abstract: The present disclosure provides systems and methods for characterizing the interaction of free radicals with various materials and the use of known interactions to isolate free radical generation from free radical interaction with a target molecule.
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3.
公开(公告)号:US20200150106A1
公开(公告)日:2020-05-14
申请号:US16745182
申请日:2020-01-16
Applicant: Wisconsin Alumni Research Foundation
Inventor: Michael R. Sussman , J. Leon Shohet , Faraz A. Choudhury , Joshua M. Blatz , Benjamin B. Minkoff , Daniel I. Benjamin
IPC: G01N33/50 , H05H1/24 , G01N33/68 , G01N33/487 , G01N1/28 , C12Q1/6876 , B01J19/08
Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
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公开(公告)号:US20230061431A1
公开(公告)日:2023-03-02
申请号:US17716499
申请日:2022-04-08
Applicant: Wisconsin Alumni Research Foundation
Inventor: Michael R. Sussman , J. Leon Shohet , Faraz A. Choudhury , Joshua M. Blatz , Benjamin B. Minkoff , Daniel I. Benjamin
IPC: G01N33/50 , B01J19/08 , C12Q1/6876 , G01N1/28 , G01N33/487 , G01N33/68 , H05H1/24
Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
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公开(公告)号:US20180045645A1
公开(公告)日:2018-02-15
申请号:US15676274
申请日:2017-08-14
Applicant: Wisconsin Alumni Research Foundation
Inventor: J. Leon Shohet , Michael R. Sussman , Faraz A. Choudhury , Benjamin B. Minkoff , Grzegorz Sabat , Joshua M. Blatz
IPC: G01N21/64
CPC classification number: G01N21/6428 , G01N2021/6439 , H01J37/32422 , H01J37/32935
Abstract: The present disclosure provides systems and methods for characterizing the interaction of free radicals with various materials and the use of known interactions to isolate free radical generation from free radical interaction with a target molecule.
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公开(公告)号:US20230375474A1
公开(公告)日:2023-11-23
申请号:US18114883
申请日:2023-02-27
Applicant: Wisconsin Alumni Research Foundation
Inventor: J. Leon Shohet , Michael R. Sussman , Faraz A. Choudhury , Benjamin B. Minkoff , Grzegorz Sabat , Joshua M. Blatz
CPC classification number: G01N21/6428 , H01J37/32935 , H01J37/32422 , H05H1/24 , B81C2201/0138 , G01N2021/6439
Abstract: The present disclosure provides systems and methods for characterizing the interaction of free radicals with various materials and the use of known interactions to isolate free radical generation from free radical interaction with a target molecule.
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公开(公告)号:US11592394B2
公开(公告)日:2023-02-28
申请号:US15676274
申请日:2017-08-14
Applicant: Wisconsin Alumni Research Foundation
Inventor: J. Leon Shohet , Michael R. Sussman , Faraz A. Choudhury , Benjamin B. Minkoff , Grzegorz Sabat , Joshua M. Blatz
Abstract: The present disclosure provides systems and methods for characterizing the interaction of free radicals with various materials and the use of known interactions to isolate free radical generation from free radical interaction with a target molecule.
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公开(公告)号:US10571460B2
公开(公告)日:2020-02-25
申请号:US15600352
申请日:2017-05-19
Applicant: Wisconsin Alumni Research Foundation
Inventor: Michael R. Sussman , J. Leon Shohet , Faraz A. Choudhury , Joshua M. Blatz , Benjamin B. Minkoff , Daniel I. Benjamin
IPC: H05H1/24 , G01N33/50 , B01J19/08 , C12Q1/6876 , G01N1/28 , G01N33/487 , G01N33/68 , H01J49/00
Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
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9.
公开(公告)号:US20170336390A1
公开(公告)日:2017-11-23
申请号:US15600352
申请日:2017-05-19
Applicant: Wisconsin Alumni Research Foundation
Inventor: Michael R. Sussman , J. Leon Shohet , Faraz A. Choudhury , Joshua M. Blatz , Benjamin B. Minkoff , Daniel I. Benjamin
CPC classification number: G01N33/50 , B01J19/088 , B01J2219/0809 , B01J2219/0894 , C12Q1/6876 , G01N1/28 , G01N33/487 , G01N33/6848 , G01N2333/765 , G01N2333/90216 , G01N2333/91215 , G01N2440/00 , H01J49/0031 , H05H1/24
Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
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