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公开(公告)号：US12247920B2
公开(公告)日：2025-03-11
申请号：US18114883
申请日：2023-02-27
Applicant: Wisconsin Alumni Research Foundation
Inventor： J. Leon Shohet , Michael R. Sussman , Faraz A. Choudhury , Benjamin B. Minkoff , Grzegorz Sabat , Joshua M. Blatz
Abstract: The present disclosure provides systems and methods for characterizing the interaction of free radicals with various materials and the use of known interactions to isolate free radical generation from free radical interaction with a target molecule.
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2.发明申请公开(公告)号：US20200150106A1
公开(公告)日：2020-05-14
申请号：US16745182
申请日：2020-01-16
Applicant: Wisconsin Alumni Research Foundation
Inventor： Michael R. Sussman , J. Leon Shohet , Faraz A. Choudhury , Joshua M. Blatz , Benjamin B. Minkoff , Daniel I. Benjamin
IPC: G01N33/50 , H05H1/24 , G01N33/68 , G01N33/487 , G01N1/28 , C12Q1/6876 , B01J19/08
Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
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公开(公告)号：US20160207022A1
公开(公告)日：2016-07-21
申请号：US15090306
申请日：2016-04-04
Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
Inventor： Michael R. Sussman , Francesco Cerrina , Kathryn Richmond , Jamison Wolfer
CPC classification number: B01J19/0046 , B01J2219/00436 , B01J2219/00529 , B01J2219/00596 , B01J2219/00608 , B01J2219/00626 , B01J2219/00722 , C12Q1/6837 , C40B50/14
Abstract: The present invention provides novel arrays of oligonucleotide probes immobilized on a solid support in the form of a chip (millichip), which can be used for rapid and inexpensive analysis of nucleic acids. The arrays can have a plurality of different oligonucleotide probes that can provide for whole genome gene expression analysis. The millichip can be used for analysis of both RNA and DNA.
Abstract translation: 本发明提供固定在芯片（millichip）形式的固体支持物上的寡核苷酸探针的新阵列，其可用于快速且廉价地分析核酸。 阵列可以具有多个可提供全基因组基因表达分析的不同寡核苷酸探针。 millichip可用于RNA和DNA的分析。
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公开(公告)号：US20230375474A1
公开(公告)日：2023-11-23
申请号：US18114883
申请日：2023-02-27
Applicant: Wisconsin Alumni Research Foundation
Inventor： J. Leon Shohet , Michael R. Sussman , Faraz A. Choudhury , Benjamin B. Minkoff , Grzegorz Sabat , Joshua M. Blatz
CPC classification number: G01N21/6428 , H01J37/32935 , H01J37/32422 , H05H1/24 , B81C2201/0138 , G01N2021/6439
Abstract: The present disclosure provides systems and methods for characterizing the interaction of free radicals with various materials and the use of known interactions to isolate free radical generation from free radical interaction with a target molecule.
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公开(公告)号：US11592394B2
公开(公告)日：2023-02-28
申请号：US15676274
申请日：2017-08-14
Applicant: Wisconsin Alumni Research Foundation
Inventor： J. Leon Shohet , Michael R. Sussman , Faraz A. Choudhury , Benjamin B. Minkoff , Grzegorz Sabat , Joshua M. Blatz
Abstract: The present disclosure provides systems and methods for characterizing the interaction of free radicals with various materials and the use of known interactions to isolate free radical generation from free radical interaction with a target molecule.
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Patent Agency Ranking
公开(公告)号：US10571460B2
公开(公告)日：2020-02-25
申请号：US15600352
申请日：2017-05-19
Applicant: Wisconsin Alumni Research Foundation
Inventor： Michael R. Sussman , J. Leon Shohet , Faraz A. Choudhury , Joshua M. Blatz , Benjamin B. Minkoff , Daniel I. Benjamin
IPC: H05H1/24 , G01N33/50 , B01J19/08 , C12Q1/6876 , G01N1/28 , G01N33/487 , G01N33/68 , H01J49/00
Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
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7.发明申请公开(公告)号：US20170336390A1
公开(公告)日：2017-11-23
申请号：US15600352
申请日：2017-05-19
Applicant: Wisconsin Alumni Research Foundation
Inventor： Michael R. Sussman , J. Leon Shohet , Faraz A. Choudhury , Joshua M. Blatz , Benjamin B. Minkoff , Daniel I. Benjamin
CPC classification number: G01N33/50 , B01J19/088 , B01J2219/0809 , B01J2219/0894 , C12Q1/6876 , G01N1/28 , G01N33/487 , G01N33/6848 , G01N2333/765 , G01N2333/90216 , G01N2333/91215 , G01N2440/00 , H01J49/0031 , H05H1/24
Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
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公开(公告)号：US20230061431A1
公开(公告)日：2023-03-02
申请号：US17716499
申请日：2022-04-08
Applicant: Wisconsin Alumni Research Foundation
Inventor： Michael R. Sussman , J. Leon Shohet , Faraz A. Choudhury , Joshua M. Blatz , Benjamin B. Minkoff , Daniel I. Benjamin
IPC: G01N33/50 , B01J19/08 , C12Q1/6876 , G01N1/28 , G01N33/487 , G01N33/68 , H05H1/24
Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
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公开(公告)号：US20180045645A1
公开(公告)日：2018-02-15
申请号：US15676274
申请日：2017-08-14
Applicant: Wisconsin Alumni Research Foundation
Inventor： J. Leon Shohet , Michael R. Sussman , Faraz A. Choudhury , Benjamin B. Minkoff , Grzegorz Sabat , Joshua M. Blatz
IPC: G01N21/64
CPC classification number: G01N21/6428 , G01N2021/6439 , H01J37/32422 , H01J37/32935
Abstract: The present disclosure provides systems and methods for characterizing the interaction of free radicals with various materials and the use of known interactions to isolate free radical generation from free radical interaction with a target molecule.
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公开(公告)号：US11300562B2
公开(公告)日：2022-04-12
申请号：US16745182
申请日：2020-01-16
Applicant: Wisconsin Alumni Research Foundation
Inventor： Michael R. Sussman , J. Leon Shohet , Faraz A. Choudhury , Joshua M. Blatz , Benjamin B. Minkoff , Daniel I. Benjamin
IPC: B01J19/08 , G01N33/50 , C12Q1/6876 , G01N1/28 , G01N33/487 , G01N33/68 , H05H1/24 , H01J49/00
Abstract: This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.
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