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公开(公告)号：US6015940A
公开(公告)日：2000-01-18
申请号：US865169
申请日：1992-04-07
CPC分类号： C12N15/8283 , C07K14/415
摘要： Potato plants and tubers that express a pokeweed antiviral protein and are thereby rendered resistant to infection by at least one of PVX and PVY and a method therefore are disclosed. A variant DNA sequence for the spring leaf form of pokeweed antiviral protein is also disclosed.
摘要翻译： 公开了表达pokeweed抗病毒蛋白质并因此使PVX和PVY中的至少一种具有抗感染性的马铃薯植物和块茎及其方法。 还公开了一种用于春季叶形式的pokeweed抗病毒蛋白的变体DNA序列。
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公开(公告)号：US6013864A
公开(公告)日：2000-01-11
申请号：US617454
申请日：1996-03-18
CPC分类号： C12N9/127 , C12N15/8283
摘要： An isolated DNA sequence which codes for a luteo replicase gene is disclosed herein. A method for providing resistance to infection by a virus by expressing a replicase gene in plants is also disclosed, as are transgenic plants containing the replicase gene.
摘要翻译： 本文公开了编码Luteo复制酶基因的分离的DNA序列。 还公开了通过在植物中表达复制酶基因来提供对病毒感染的抗性的方法，以及含有复制酶基因的转基因植物。
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公开(公告)号：US20110263540A1
公开(公告)日：2011-10-27
申请号：US13055813
申请日：2009-07-24
IPC分类号： A61K31/655 , A61K31/47 , A61K31/44 , A61K31/4025 , A61K31/402 , G06G7/60 , A61K31/454 , A61K31/381 , A61K31/4015 , A61K31/404 , A61K31/4035 , A61P39/02 , A61K31/196 , A61K31/5377
CPC分类号： A61K31/04 , A61K31/167 , A61K31/343 , A61K31/40 , A61K31/4184 , A61K39/00 , A61K45/06 , G16B15/00 , G16C20/50 , A61K2300/00
摘要： Small-molecule inhibitors of a protein synthesis inhibiting toxin, e.g., ricin, abrin, Shiga, and Shiga-like toxins, as well as methods of using the inhibitors are provided. Further provided are methods of identifying small-molecule inhibitors of a protein synthesis inhibiting toxin.
摘要翻译： 提供抑制蛋白质合成的毒素的小分子抑制剂，例如蓖麻毒素，相思豆毒素，志贺和滋贺样毒素，以及使用抑制剂的方法。 还提供了鉴定抑制蛋白质合成的毒素的小分子抑制剂的方法。
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公开(公告)号：US5792937A
公开(公告)日：1998-08-11
申请号：US803972
申请日：1997-02-21
CPC分类号： C12N9/127 , C12N15/8283
摘要： A DNA sequence encoding a PVX replicase gene obtained from ORF1 of a PVX genome is provided. A plant gene containing the PVX replicase coding region is also provided as is a truncated derivative of the PVX replicase gene. A PVX replicase gene is inserted into a plant to confer resistance to the plant against PVX infection when the PVX replicase gene is sufficiently expressed.
摘要翻译： 提供了从PVX基因组的ORF1获得的编码PVX复制酶基因的DNA序列。 含有PVX复制酶编码区的植物基因也是PVX复制酶基因的截短衍生物。 当PVX复制酶基因被充分表达时，将PVX复制酶基因插入植物中以赋予植物抵抗PVX感染的抗性。
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公开(公告)号：US5986175A
公开(公告)日：1999-11-16
申请号：US559221
申请日：1995-11-16
CPC分类号： C12N9/127 , C12N15/8283
摘要： An isolated DNA sequence which codes for a potyvirus replicase gene is disclosed herein. A method for providing resistance to infection by a virus by expressing a replicase gene in plants is also disclosed. Transgenic potato plants and tubers containing the replicase gene are also disclosed.
摘要翻译： 本文公开了编码病毒复制酶基因的分离的DNA序列。 还公开了通过在植物中表达复制酶基因来提供抗病毒感染的方法。 还公开了含有复制酶基因的转基因马铃薯植物和块茎。
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公开(公告)号：US5773701A
公开(公告)日：1998-06-30
申请号：US803973
申请日：1997-02-21
CPC分类号： C12N9/127 , C12N15/8283
摘要： A DNA sequence encoding a PVX replicase gene obtained from ORF1 of a PVX genome is provided. A plant gene containing the PVX replicase coding region is also provided as is a truncated derivative of the PVX replicase gene. A PVX replicase gene is inserted into a plant to confer resistance to the plant against PVX infection when the PVX replicase gene is sufficiently expressed.
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