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公开(公告)号:US20140079750A1
公开(公告)日:2014-03-20
申请号:US14110933
申请日:2012-03-29
申请人: Xiaoke Li , Yan Deng , Guan-Jun Ding , Yong Xu
发明人: Xiaoke Li , Yan Deng , Guan-Jun Ding , Yong Xu
CPC分类号: A61K6/0023 , A61K6/0008 , A61K8/0241 , A61K8/19 , A61K8/24 , A61K2800/412 , A61Q11/00
摘要: Oral care compositions suitable for whitening and remineralizing teeth are described. The oral care compositions comprise a phosphate source and regeneration-source calcium salt having a particle size of five (5) microns or less so that in-situ hydroxyapatite may be generated upon use.
摘要翻译: 描述了适用于美白和再矿化牙齿的口腔护理组合物。 口腔护理组合物包含粒径为五(5)微米或更小的磷酸盐源和再生源钙盐,使得在使用时可能产生原位羟基磷灰石。
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公开(公告)号:US09180318B2
公开(公告)日:2015-11-10
申请号:US13580745
申请日:2011-02-18
申请人: Yan Deng , Xiaoke Li , ZhiQing Zhang , GuoQing Zhao
发明人: Yan Deng , Xiaoke Li , ZhiQing Zhang , GuoQing Zhao
摘要: A single-phase oral care composition is described. The composition comprises both calcium and phosphate sources and is substantially free of water and is substantially free of generated calcium phosphate comprising compounds. The single-phase oral care composition is stable, maintains good viscosity characteristics and avoids the need for compartmentalized packaging.
摘要翻译: 描述了单相口腔护理组合物。 该组合物包含钙和磷酸盐源,并且基本上不含水,并且基本上不含所产生的含磷酸钙的化合物。 单相口腔护理组合物稳定,保持良好的粘度特性,避免了隔室包装的需要。
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公开(公告)号:US20120315228A1
公开(公告)日:2012-12-13
申请号:US13580745
申请日:2011-02-18
申请人: Yan Deng , Xiaoke Li , ZhiQing Zhang , GuoQing Zhao
发明人: Yan Deng , Xiaoke Li , ZhiQing Zhang , GuoQing Zhao
摘要: A single-phase oral care composition is described. The composition comprises both calcium and phosphate sources and is substantially free of water and is substantially free of generated calcium phosphate comprising compounds. The single-phase oral care composition is stable, maintains good viscosity characteristics and avoids the need for compartmentalized packaging.
摘要翻译: 描述了单相口腔护理组合物。 该组合物包含钙和磷酸盐源,并且基本上不含水,并且基本上不含所产生的含磷酸钙的化合物。 单相口腔护理组合物稳定,保持良好的粘度特性,避免了隔室包装的需要。
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公开(公告)号:US20130171221A1
公开(公告)日:2013-07-04
申请号:US13820153
申请日:2011-03-11
申请人: Yan Deng , Guanjun Ding , Xiaoke Li
发明人: Yan Deng , Guanjun Ding , Xiaoke Li
CPC分类号: A61K8/25 , A61K8/0241 , A61K8/19 , A61K8/24 , A61K8/27 , A61K8/29 , A61K2800/412 , A61K2800/61 , A61Q11/00
摘要: Oral care compositions with composite particle actives are described. The composite particle actives have a core and a coating whereby the coating interacts with phosphate ions to produce calcium and phosphate reaction products that are suitable to adhere to tooth enamel and/or dentin in order to improve the characteristics of teeth.
摘要翻译: 描述了具有复合颗粒活性物质的口腔护理组合物。 复合颗粒活性剂具有核心和涂层,由此涂层与磷酸根离子相互作用以产生适于粘附到牙釉质和/或牙本质上的钙和磷酸盐反应产物,以改善牙齿的特性。
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公开(公告)号:US08257721B2
公开(公告)日:2012-09-04
申请号:US12517562
申请日:2007-12-04
申请人: Michael Francis Butler , Yan Deng , Mary Heppenstall-Butler , Andrew Joiner , Haiyan Li , Xiaoke Li
发明人: Michael Francis Butler , Yan Deng , Mary Heppenstall-Butler , Andrew Joiner , Haiyan Li , Xiaoke Li
CPC分类号: A61K8/24 , A61K8/25 , A61K33/06 , A61K33/08 , A61K33/10 , A61K33/42 , A61K45/06 , A61Q11/00 , A61K2300/00
摘要: An oral care product comprising a source of calcium ions, a source of phosphate ions, and an insoluble whitening agent for deposition onto the teeth, characterized in that the source of calcium ions and the source of phosphate ions are physically separate prior to the use of the product.
摘要翻译: 一种包含钙离子源,磷酸根离子源和用于沉积到牙齿上的不溶性增白剂的口腔护理产品,其特征在于钙离子源和磷酸根离子源在使用前 该产品。
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公开(公告)号:US20130164359A1
公开(公告)日:2013-06-27
申请号:US13820154
申请日:2011-03-11
申请人: Yan Deng , Guanjun Ding , Xiaoke Li
发明人: Yan Deng , Guanjun Ding , Xiaoke Li
CPC分类号: A61K8/0241 , A61K8/19 , A61K8/25 , A61K8/29 , A61K2800/412 , A61K2800/621 , A61K2800/622 , A61K2800/651 , A61Q11/00 , C09C1/3661
摘要: Composite particle actives suitable for use in oral care compositions are described. The composite particle actives have a core and a coating whereby the coating interacts with phosphate ions to produce calcium and phosphate reaction products that are suitable to adhere to tooth enamel and/or dentin in order to improve characteristics of teeth.
摘要翻译: 描述适用于口腔护理组合物的复合颗粒活性剂。 复合颗粒活性剂具有核心和涂层,由此涂层与磷酸根离子相互作用以产生适于粘附到牙釉质和/或牙本质上的钙和磷酸盐反应产物,以改善牙齿的特性。
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公开(公告)号:US20100150974A1
公开(公告)日:2010-06-17
申请号:US12517562
申请日:2007-12-04
申请人: Michael Francis Butler , Yan Deng , Mary Heppenstall-Butler , Andrew Joiner , Haiyan Li , Xiaoke Li
发明人: Michael Francis Butler , Yan Deng , Mary Heppenstall-Butler , Andrew Joiner , Haiyan Li , Xiaoke Li
CPC分类号: A61K8/24 , A61K8/25 , A61K33/06 , A61K33/08 , A61K33/10 , A61K33/42 , A61K45/06 , A61Q11/00 , A61K2300/00
摘要: An oral care product comprising a source of calcium ions, a source of phosphate ions, and an insoluble whitening agent for deposition onto the teeth, characterised in that the source of calcium ions and the source of phosphate ions are physically separate prior to the use of the product.
摘要翻译: 一种包含钙离子源,磷酸根离子源和用于沉积到牙齿上的不溶性增白剂的口腔护理产品,其特征在于钙离子源和磷酸根离子源在使用前 该产品。
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公开(公告)号:US20100143423A1
公开(公告)日:2010-06-10
申请号:US12517365
申请日:2007-11-23
申请人: Michael Francis Butler , Yan Deng , Mary Heppenstall-Butler , Andrew Joiner , Haiyan Li , Xiaoke Li
发明人: Michael Francis Butler , Yan Deng , Mary Heppenstall-Butler , Andrew Joiner , Haiyan Li , Xiaoke Li
CPC分类号: A61K8/24 , A61K8/25 , A61K33/06 , A61K33/08 , A61K33/10 , A61K33/42 , A61K45/06 , A61Q11/00 , A61K2300/00
摘要: An oral care product comprising a first composition comprising an insoluble calcium salt that is not a calcium phosphate salt, a second independent composition comprising a source of phosphate ions, and a means for delivering each of the compositions to the surface of the teeth.
摘要翻译: 一种口腔护理产品,其包含第一组合物,所述第一组合物包含不是磷酸钙盐的不溶性钙盐,包含磷酸盐离子源的第二独立组合物和用于将每种组合物输送到牙齿表面的装置。
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公开(公告)号:US09149419B2
公开(公告)日:2015-10-06
申请号:US12517560
申请日:2007-12-04
IPC分类号: A61K8/02 , A61K8/24 , A61K8/25 , A61K33/06 , A61K33/08 , A61K33/10 , A61K33/42 , A61K45/06 , A61Q11/00
CPC分类号: A61K8/24 , A61K8/25 , A61K33/06 , A61K33/08 , A61K33/10 , A61K33/42 , A61K45/06 , A61Q11/00 , A61K2300/00
摘要: An Oral care product is provided which includes a mesoporous calcium silicate biomaterial (MCSB) dispersed in a polymeric material matrix. MCSB is an insoluble composite material of calcium oxide-silica.
摘要翻译: 提供了一种口腔护理产品,其包括分散在聚合材料基质中的介孔硅酸钙生物材料(MCSB)。 MCSB是氧化钙 - 二氧化硅的不溶性复合材料。
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公开(公告)号:US20090319052A1
公开(公告)日:2009-12-24
申请号:US12309789
申请日:2007-07-23
CPC分类号: A61L27/56 , A61K6/027 , A61K8/25 , A61L27/10 , A61L27/425 , A61Q11/00 , C03C1/006 , C03C3/04 , C03C4/0007 , C04B35/057 , C04B35/14 , C04B35/447 , C04B38/0032 , C04B38/0045 , C04B2111/00836 , C04B38/0054
摘要: A calcium oxide-silica composite biomaterial either in amorphous state or crystalline state having an average pore size, as determined by the BET method, in the range of from 0.8 to 4 nm, wherein the calcium oxide-silica content of the biomaterial is at least 80 wt %, the balance being optionally one or more other materials and wherein the molar ratio of calcium oxide to silica is at least 0.1.
摘要翻译: 一种氧化钙 - 二氧化硅复合生物材料,其无定形状态或结晶态具有通过BET法测定的平均孔径,范围为0.8至4nm,其中生物材料的氧化钙 - 二氧化硅含量至少为 80重量%,余量可选地为一种或多种其它材料,并且其中氧化钙与二氧化硅的摩尔比为至少0.1。
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