公开(公告)号：US20190231650A1

公开(公告)日：2019-08-01

申请号：US16329637

申请日：2017-08-03

申请人： SHANDONG SINOCERA FUNCTIONAL MATERIAL CO., LTD.

发明人： Aimin YANG ,  Xuekui MO ,  Xibin SONG

IPC分类号： A61K6/02 ,  A61C13/083 ,  A61C13/00 ,  A61K6/00 ,  C04B35/488 ,  C04B35/626 ,  C04B35/634 ,  C04B35/64

CPC分类号： A61K6/024 ,  A61C13/0022 ,  A61C13/083 ,  A61K6/0008 ,  A61K6/02 ,  C04B35/48 ,  C04B35/488 ,  C04B35/622 ,  C04B35/626 ,  C04B35/6261 ,  C04B35/6264 ,  C04B35/62695 ,  C04B35/63416 ,  C04B35/63488 ,  C04B35/64 ,  C04B2235/3246 ,  C04B2235/5409 ,  C04B2235/5436 ,  C04B2235/604 ,  C04B2235/608 ,  C04B2235/6567 ,  C04B2235/9653

摘要： Provided is a light-transmissive zirconia sintered body, obtained by preparing a green body from a powder for the light-transmissive zirconia sintered body by means of isostatic pressing, and sintering the green body at a high temperature and normal pressure after degreasing and biscuit firing. The light-transmissive zirconia sintered body is prepared by dispersing zirconia powder in water, adding an appropriate amount of a dispersant and a binder, mixing the mixture to form a slurry, and spray-granulating same, wherein the molar percentage of yttrium oxide in the zirconia powder is 3-5%. The light-transmissive zirconia sintered body can be used for preparing a fixed dental prosthesis.

公开(公告)号：US20180355200A1

公开(公告)日：2018-12-13

申请号：US15740869

申请日：2016-06-29

申请人： Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

发明人： Uri BANIN ,  Hermona SOREQ ,  Shlomo MAGDASSI ,  Nir WAISKOPF ,  Yuval BEN-SHAHAR ,  Amol ASHOK PAWAR ,  Shira HALIVNI

IPC分类号： C09D11/38 ,  C09D11/101 ,  G03F7/029

CPC分类号： C09D11/38 ,  A61K6/0008 ,  A61K6/0052 ,  A61K6/0073 ,  A61K6/083 ,  B33Y70/00 ,  B82Y30/00 ,  C09D11/101 ,  G03F7/0037 ,  G03F7/029 ,  C08L33/26

摘要： Provided is a novel photoinitiator in the form of a hybrid nanoparticle constructed of a semiconductor and metallic regions, and uses thereof.

公开(公告)号：US10080708B2

公开(公告)日：2018-09-25

申请号：US15102483

申请日：2014-12-08

申请人： 3M INNOVATIVE PROPERTIES COMPANY

发明人： Robert Peez ,  Peter Braun ,  Markus Mikulla ,  Rainer Guggenberger

IPC分类号： A61K6/00 ,  A61K6/083

CPC分类号： A61K6/0835 ,  A61K6/0008 ,  A61K6/0073 ,  A61K6/0088

摘要： The invention relates to a kit of parts for preparing a glass ionomer cement, the kit comprising a Part A and a Part B, Part A being a powder and comprising an acid-reactive filler in an amount above about 60 wt. %, the acid-reactive filler having a mean particle size in the range of 3.5 to 10 μm, an non acid-reactive filler in an amount above about 1 wt. %, the non acid-reactive filler having a mean particle size in the range of 1.0 to 3.5 μm, Part A not comprising a polyacid in an amount above about 1 wt. %, wt. % with respect to the weight of Part A, Part B being a liquid and comprising a polyacid in an amount above about 30 wt. %, water, a complexing agent, wt. % with respect to the weight of Part B. The invention also relates to a process of producing a hardenable or hardening composition and use thereof in the dental field.

公开(公告)号：US20180127317A1

公开(公告)日：2018-05-10

申请号：US15574646

申请日：2016-05-26

申请人： 3M INNOVATIVE PROPERTIES COMPANY

发明人： Helmar B. Mayr ,  Malte Korten ,  Christine M. Andres ,  Brant U. Kolb ,  Holger Hauptmann ,  Gallus Schechner ,  Michael Jahns ,  Kathleen M. Humpal ,  Melissa A. Lackey ,  Paul D. Pennington

IPC分类号： C04B35/486 ,  C04B35/624 ,  C04B35/64 ,  A61K6/00 ,  A61K6/02 ,  B28B1/00 ,  B33Y80/00 ,  B33Y10/00

CPC分类号： C04B35/486 ,  A61C5/70 ,  A61C5/73 ,  A61C5/77 ,  A61C13/0013 ,  A61C13/0019 ,  A61C13/083 ,  A61C13/09 ,  A61K6/0008 ,  A61K6/0205 ,  A61K6/0215 ,  A61K6/024 ,  A61K6/0245 ,  A61K6/025 ,  B28B1/001 ,  B33Y10/00 ,  B33Y70/00 ,  B33Y80/00 ,  C04B35/624 ,  C04B35/64 ,  C04B2235/3206 ,  C04B2235/3208 ,  C04B2235/3225 ,  C04B2235/3227 ,  C04B2235/3229 ,  C04B2235/5454 ,  C04B2235/6026 ,  C04B2235/762 ,  C04B2235/765 ,  C04B2235/9653

摘要： The invention relates to the use of a printing sol as construction material in an additive manufacturing process for producing a 3-dim article, the printing sol comprising solvent(s), nano-sized crystalline zirconia particles in an amount from 2 to 25 vol.-% with respect to the volume of the sol, the average primary particle size of the nano-sized crystalline zirconia particles being in a range up to 50 nm, a first monomer being a polymerizable surface modification agent represented by formula A-B, with A being capable of attaching to the surface of the nano-sized crystalline zirconia particles and B being a radiation curable group, optionally a second monomer, the second monomer comprising at least one radiation curable moiety but no acidic or silane group(s), photo initiator(s). The invention also relates to a ceramic article obtainable according to such a process.

公开(公告)号：US09925124B2

公开(公告)日：2018-03-27

申请号：US13408050

申请日：2012-02-29

申请人： Yusei Kadobayashi ,  Masako Shigezawa ,  Keiji Takahashi

发明人： Yusei Kadobayashi ,  Masako Shigezawa ,  Keiji Takahashi

IPC分类号： A61K6/083 ,  A61K6/00 ,  A61C13/00

CPC分类号： A61K6/0008 ,  A61C13/0022 ,  A61K6/083 ,  C08L33/10

摘要： Provided is a dental composition comprising a first largest group of particles and resin matrix, wherein the first largest group consists of particles whose particle size ranges from 0.7 to 1.5 times the representative particle size of the first largest fraction in a population of particles included in the composition whose particle size ranges from 110 to 1000 μm; and wherein the ratio of the number of particles included in the first largest group to the number of particles whose particle size ranges from 0.5 to 2.0 times the representative particle size of the first largest fraction is equal to or more than 0.8.

公开(公告)号：US20180064613A1

公开(公告)日：2018-03-08

申请号：US15707742

申请日：2017-09-18

申请人： South Dakota Board of Regents

发明人： Grigoriy Sereda ,  Joshua Brower

IPC分类号： A61K6/00 ,  A61Q11/00 ,  A61K8/34 ,  A23G4/06 ,  A61C19/06 ,  A61C19/08 ,  A61K8/73 ,  A61K8/60 ,  A61K8/365 ,  A61K8/29 ,  A61K8/26 ,  A61K8/25 ,  A61K8/24 ,  A61K8/11 ,  A61K8/02

CPC分类号： A61K6/0047 ,  A23G4/06 ,  A23G4/064 ,  A61C5/62 ,  A61C19/063 ,  A61C19/08 ,  A61K6/0008 ,  A61K6/007 ,  A61K8/0241 ,  A61K8/11 ,  A61K8/24 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61K8/347 ,  A61K8/365 ,  A61K8/604 ,  A61K8/733 ,  A61K8/735 ,  A61K8/736 ,  A61K2800/28 ,  A61K2800/412 ,  A61K2800/413 ,  A61K2800/612 ,  A61K2800/884 ,  A61K2800/92 ,  A61Q11/00

摘要： The present invention relates to a method of remineralizing and desensitizing teeth utilizing the sequential steps of first applying to the teeth a first component that attaches to the teeth and secondly applying to the teeth treated with the first component a second component that attaches to the first component.

公开(公告)号：US20170333190A1

公开(公告)日：2017-11-23

申请号：US15491564

申请日：2017-04-19

申请人： Warsaw Orthopedic, Inc.

发明人： Scott M. Vickers ,  Jeffrey L. Scifert ,  Ian R. Dunkley

IPC分类号： A61F2/28 ,  A61K6/033 ,  A61K6/00 ,  A61K6/02 ,  A61F2/30

CPC分类号： A61F2/28 ,  A61F2002/2835 ,  A61F2002/30032 ,  A61F2002/30062 ,  A61F2002/30677 ,  A61F2310/00293 ,  A61F2310/00359 ,  A61F2310/00371 ,  A61K6/0008 ,  A61K6/0205 ,  A61K6/033 ,  A61L27/3608 ,  A61L27/46 ,  A61L27/58 ,  A61L2430/02 ,  C08L89/06

摘要： Provided is an implantable composite which includes a plurality of resorbable ceramic particles with or without a biodegradable polymer. The resorbable ceramic particles can be granules including carbonated hydroxyapatite and tricalcium phosphate in a ratio of 5:95 to 70:30. Some resorbable ceramic particles are granules, which include carbonated hydroxyapatite and β tricalcium phosphate in a ratio of 5:95 to 70:30. The resorbable ceramic particles have a particle size from about 0.4 to about 3.5 mm. The implantable composite is configured to tit at or near a bone defect as an autograft extender to promote bone growth. Methods of using the implantable composite are also provided.

公开(公告)号：US09822039B1

公开(公告)日：2017-11-21

申请号：US15240673

申请日：2016-08-18

申请人： Ivoclar Vivadent AG

发明人： Wei Xu ,  Yijun Wang ,  Dmitri Brodkin

IPC分类号： C04B35/486 ,  C04B35/624 ,  C04B35/634 ,  C04B35/638 ,  C01G25/02 ,  C08K3/22 ,  C08L71/02 ,  C02F1/44 ,  B01D61/00 ,  C02F103/12

CPC分类号： C04B35/486 ,  A61K6/0008 ,  A61K6/024 ,  B01D61/002 ,  B01D61/005 ,  B01D2311/02 ,  B01D2311/04 ,  C01G25/02 ,  C01P2004/64 ,  C02F1/445 ,  C02F2103/12 ,  C04B35/488 ,  C04B35/4885 ,  C04B35/624 ,  C04B35/63416 ,  C04B35/63488 ,  C04B35/638 ,  C04B2235/3217 ,  C04B2235/5454 ,  C04B2235/5463 ,  C04B2235/602 ,  C04B2235/606 ,  C04B2235/608 ,  C04B2235/61 ,  C04B2235/612 ,  C04B2235/762 ,  C04B2235/765 ,  C04B2235/77 ,  C04B2235/781 ,  C04B2235/785 ,  C04B2235/96 ,  C04B2235/9653 ,  C08K3/22 ,  C08L71/02

摘要： Provided are metal oxide ceramic materials and intermediate materials thereof (e.g., nanozirconia gels, nanozirconia green bodies, pre-sintered ceramic bodies, zirconia dental ceramic materials, and dental articles). The nanozirconia gels are formable gels. Also provided are methods of making and using the metal oxide materials and intermediate materials. The nanozirconia gels can be made using, for example, osmotic processing. The nanozirconia gels can be used to make nanozirconia green bodies, pre-sintered ceramic bodies, zirconia dental ceramic materials, and dental article. The nanozirconia green bodies, pre-sintered ceramic bodies, zirconia dental ceramic materials, and dental articles have desirable properties (e.g., optical properties and mechanical properties).

公开(公告)号：US09801842B2

公开(公告)日：2017-10-31

申请号：US14299350

申请日：2014-06-09

申请人： The Regents of the University of Michigan

发明人： James R. Baker, Jr. ,  Sivaprakash Rathinavelu ,  Paul E. Makidon ,  John J. LiPuma ,  Shraddha Nigavekar

IPC分类号： A61K31/198 ,  A61K47/32 ,  A61K33/14 ,  A61K45/06 ,  A61K6/00 ,  A61K9/00 ,  A61K9/107 ,  A61K31/22 ,  A61K31/337 ,  A61K31/573 ,  A61K31/7048 ,  B82Y5/00 ,  A01N25/04 ,  A23L29/10 ,  A23L33/135

CPC分类号： A61K31/198 ,  A01N25/04 ,  A23L29/10 ,  A23L33/135 ,  A23V2002/00 ,  A61K6/0008 ,  A61K9/0078 ,  A61K9/1075 ,  A61K31/22 ,  A61K31/337 ,  A61K31/573 ,  A61K31/7048 ,  A61K33/14 ,  A61K45/06 ,  A61K47/32 ,  B82Y5/00 ,  A23V2200/25

摘要： The present invention relates to methods and compositions for treating pulmonary infection. In particular, the present invention provides nanoemulsion compositions and methods of using the same to treat bacteria associated with biofilms (e.g., found in pulmonary infections). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine), industrial, and research applications.

公开(公告)号：US09717248B2

公开(公告)日：2017-08-01

申请号：US14891951

申请日：2014-05-16

申请人： The University of Bristol

发明人： Michele Emily Redmond

IPC分类号： A01N47/44 ,  A01N25/12 ,  A01N25/22 ,  A61K8/43 ,  A61K8/02 ,  A61L15/20 ,  A61L15/44 ,  A61L29/08 ,  A61L29/16 ,  A61Q11/00 ,  A01N25/34 ,  A61K6/00 ,  C09D5/14 ,  C09D7/12

CPC分类号： A01N47/44 ,  A01N25/12 ,  A01N25/22 ,  A01N25/34 ,  A61K6/0008 ,  A61K6/0067 ,  A61K8/0245 ,  A61K8/044 ,  A61K8/43 ,  A61K8/55 ,  A61K2800/413 ,  A61K2800/74 ,  A61L15/20 ,  A61L15/44 ,  A61L29/08 ,  A61L29/16 ,  A61L2300/206 ,  A61L2300/404 ,  A61L2300/602 ,  A61L2300/606 ,  A61L2420/00 ,  A61Q11/00 ,  C09D5/14 ,  C09D7/63 ,  C09D7/68 ,  A01N25/08 ,  A01N25/10 ,  A61K6/0835 ,  C08L33/08

摘要： Antimicrobial micro- or nanoparticles comprising a chlorhexidine salt and an anion, and a method of making the antimicrobial micro- or nanoparticle, are disclosed. The anion in the salt is selected form oxoanions and partially hydrogenated oxoanions of phosphorus, carbon, nitrogen, and sulfur.