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公开(公告)号:US5911950A
公开(公告)日:1999-06-15
申请号:US941384
申请日:1997-09-30
IPC分类号: A61L2/16 , A01N59/00 , A61L2/04 , A61L2/10 , A61L2/14 , A61L2/20 , A61L2/24 , A61L2/26 , B01J7/00 , B65D65/38 , B65D65/40 , B65D81/24 , C01B15/01 , C01B15/03 , C01B15/037 , C01B15/06 , C01B15/08 , C01B15/10 , C01B15/14 , C01B15/16 , C01D7/00 , C07D233/64
CPC分类号: A61L2/208 , A01N59/00 , A61L2/14 , A61L2/20 , A61L2/26 , C01B15/01 , C01B15/03 , C01B15/06 , C01B15/08 , C01B15/103 , C01B15/14 , C01B15/16 , A61L2202/122 , A61L2202/24 , Y10S261/65 , Y10T428/1352 , Y10T428/1355 , Y10T428/1359 , Y10T428/1376 , Y10T428/1379 , Y10T428/1383
摘要: A system to deliver gas/vapor from solid materials. Specifically, the delivery system for the use of gas or vapor released from a solid material, such as a non-aqueous/solid hydrogen peroxide complex. The system is comprised of a delivery system that is configured to receive a plurality of disks containing the solid material and provide these disks into an injector. The injector heats the disks to produce a gas or vapor that is then provided into a chamber. The sterilization process can be done by gas or vapor alone, or in combination with plasma or ultra violet radiation. In particular, a control system automatically induces the delivery system to provide the injector with a disk and then remove the disk once the injection sequence is complete.
摘要翻译: 从固体材料输送气体/蒸汽的系统。 具体地,用于使用从固体材料如非水/固体过氧化氢络合物释放的气体或蒸汽的输送系统。 该系统包括配送系统,该配送系统被配置为接收包含固体材料的多个盘,并将这些盘提供到喷射器中。 喷射器加热盘以产生气体或蒸气,然后将其提供到室中。 灭菌过程可以通过单独的气体或蒸气,或与等离子体或紫外线辐射结合进行。 特别地,控制系统自动地引导传送系统以向注射器提供磁盘,然后一旦注射顺序完成就移除磁盘。
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公开(公告)号:US5939033A
公开(公告)日:1999-08-17
申请号:US744741
申请日:1996-10-28
申请人: Richard Jed Kendall , Xiaolan Chen , Michael Hahs , Paul Taylor Jacobs , Szu-Min Lin , Robert M. Spencer , Harold R. Williams
发明人: Richard Jed Kendall , Xiaolan Chen , Michael Hahs , Paul Taylor Jacobs , Szu-Min Lin , Robert M. Spencer , Harold R. Williams
IPC分类号: A61L2/16 , A01N59/00 , A61L2/04 , A61L2/10 , A61L2/14 , A61L2/20 , A61L2/24 , A61L2/26 , B01J7/00 , B65D65/38 , B65D65/40 , B65D81/24 , C01B15/01 , C01B15/03 , C01B15/037 , C01B15/06 , C01B15/08 , C01B15/10 , C01B15/14 , C01B15/16 , C01D7/00 , C07D233/64
CPC分类号: A61L2/208 , A01N59/00 , A61L2/14 , A61L2/20 , A61L2/26 , C01B15/01 , C01B15/03 , C01B15/06 , C01B15/08 , C01B15/103 , C01B15/14 , C01B15/16 , A61L2202/122 , A61L2202/24 , Y10S261/65 , Y10T428/1352 , Y10T428/1355 , Y10T428/1359 , Y10T428/1376 , Y10T428/1379 , Y10T428/1383
摘要: A system to deliver gas/vapor from solid materials. Specifically, the delivery system for the use of gas or vapor released from a solid material, such as a non-aqueous/solid hydrogen peroxide complex. The system is comprised of a delivery system that is configured to receive a plurality of disks containing the solid material and provide these disks into an injector. The injector heats the disks to produce a gas or vapor that is then provided into a chamber. The sterilization process can be done by gas or vapor alone, or in combination with plasma or ultra violet radiation. In particular, a control system automatically induces the delivery system to provide the injector with a disk and then remove the disk once the injection sequence is complete.
摘要翻译: 从固体材料输送气体/蒸汽的系统。 具体地,用于使用从固体材料如非水/固体过氧化氢络合物释放的气体或蒸汽的输送系统。 该系统包括配送系统,该配送系统被配置为接收包含固体材料的多个盘,并将这些盘提供到喷射器中。 喷射器加热盘以产生气体或蒸气,然后将其提供到室中。 灭菌过程可以通过单独的气体或蒸气,或与等离子体或紫外线辐射结合进行。 特别地,控制系统自动地引导传送系统以向注射器提供磁盘,然后一旦注射顺序完成就移除磁盘。
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公开(公告)号:US06495100B1
公开(公告)日:2002-12-17
申请号:US09470244
申请日:1999-12-22
申请人: Szu-Min Lin , Anthony Lemus , Harold R. Williams , Paul Taylor Jacobs , Tralance O. Addy , Jon Morrell Jacobs
发明人: Szu-Min Lin , Anthony Lemus , Harold R. Williams , Paul Taylor Jacobs , Tralance O. Addy , Jon Morrell Jacobs
IPC分类号: A61L220
CPC分类号: A61L2/208 , A61L2/14 , A61L2/16 , A61L2202/122 , A61L2202/14 , A61L2202/24
摘要: A method for sterilizing medical devices and similar instruments in diffusion-restricted containers is provided. The sterilization method includes placing a liquid solution containing vaporizable germicide such as hydrogen peroxide into the diffusion-restricted container and vaporizing the germicide. The containers can be attachable and detachable to a sterilization system, and used as a vacuum chamber. An attachable/detachable container containing an article to be sterilized can be nested with a second container, and the article and inside and outside of the inner container are sterilized. The sterile article inside the nested containers can be transported and the sterile inner container with the sterilized article can removed from the outer container and placed in a sterile environment without contaminating the sterile environment. The sterile article can then be removed from the sterile container and utilized. Alternatively, the sterilization method may include introducing germicide vapor into an attachable/detachable container.
摘要翻译: 提供了一种在扩散限制容器中对医疗器械和类似仪器进行消毒的方法。 灭菌方法包括将含有可蒸发的杀菌剂如过氧化氢的液体溶液放置在扩散限制容器中并使杀菌剂蒸发。 容器可以安装和拆卸到灭菌系统,并用作真空室。 容纳待灭菌物品的可装卸的容器可以嵌入第二容器,并且将内部容器的内部和外部消毒。 嵌套容器内的无菌制品可以运输,具有灭菌制品的无菌内容器可以从外容器中取出并放置在无菌环境中,而不会污染无菌环境。 然后将无菌制品从无菌容器中取出并使用。 或者,灭菌方法可以包括将杀菌剂蒸气引入可附接/可拆卸的容器中。
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公开(公告)号:US5785934A
公开(公告)日:1998-07-28
申请号:US716094
申请日:1996-09-19
申请人: Paul Taylor Jacobs , Szu-Min Lin , Xiaolan Chen
发明人: Paul Taylor Jacobs , Szu-Min Lin , Xiaolan Chen
IPC分类号: A61L2/16 , A61L20060101 , A61L2/04 , A61L2/06 , A61L2/10 , A61L2/14 , A61L2/18 , A61L2/20 , A61L2/24 , A61L2/26 , B01J7/00 , B65D65/38 , B65D65/40 , B65D81/24 , C01B15/01 , C01B15/03 , C01B15/037 , C01B15/06 , C01B15/08 , C01B15/10 , C01B15/14 , C01B15/16 , C01D7/00 , A61L9/00
CPC分类号: A61L2/14 , A61L2/208 , A61L2/26 , C01B15/01 , C01B15/03 , C01B15/037 , C01B15/06 , C01B15/08 , C01B15/103 , C01B15/14 , C01B15/16 , A61L2202/122 , A61L2202/24
摘要: An apparatus and process for hydrogen peroxide vapor sterilization of medical instruments and similar devices make use of hydrogen peroxide vapor released from an inorganic hydrogen peroxide complex. The peroxide vapor can be released at room temperature and atmospheric pressure; however, the pressure used can be less than 50 torr and the temperature greater than 86.degree. C. to facilitate the release of hydrogen peroxide vapor. Preferred hydrogen peroxide complexes for use in the invention include Na.sub.4 P.sub.2 O.sub.7.3 H.sub.2 O.sub.2 and KH.sub.2 PO.sub.4.H.sub.2 O.sub.2. The heating rate can be greater than 5.degree. C. Optionally, a plasma can be used in conjunction with the vapor.
摘要翻译: 用于医疗器械和类似装置的过氧化氢蒸气灭菌的装置和方法利用从无机过氧化氢络合物释放的过氧化氢蒸气。 过氧化物蒸汽可以在室温和大气压下释放; 然而,使用的压力可以小于50托,并且温度大于86℃以促进过氧化氢蒸气的释放。 用于本发明的优选的过氧化氢配合物包括Na 4 P 2 O 7·3H 2 O 2和KH 2 PO 4·H 2 O 2。 加热速率可以大于5℃。任选地,等离子体可以与蒸气结合使用。
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公开(公告)号:US5904897A
公开(公告)日:1999-05-18
申请号:US940323
申请日:1997-09-30
IPC分类号: A61L2/16 , A01N59/00 , A61L2/04 , A61L2/10 , A61L2/14 , A61L2/20 , A61L2/24 , A61L2/26 , B01J7/00 , B65D65/38 , B65D65/40 , B65D81/24 , C01B15/01 , C01B15/03 , C01B15/037 , C01B15/06 , C01B15/08 , C01B15/10 , C01B15/14 , C01B15/16 , C01D7/00 , C07D233/64
CPC分类号: A61L2/208 , A01N59/00 , A61L2/14 , A61L2/20 , A61L2/26 , C01B15/01 , C01B15/03 , C01B15/06 , C01B15/08 , C01B15/103 , C01B15/14 , C01B15/16 , A61L2202/122 , A61L2202/24 , Y10S261/65 , Y10T428/1352 , Y10T428/1355 , Y10T428/1359 , Y10T428/1376 , Y10T428/1379 , Y10T428/1383
摘要: A system to deliver gas/vapor from solid materials. Specifically, the delivery system for the use of gas or vapor released from a solid material, such as a non-aqueous/solid hydrogen peroxide complex. The system is comprised of a delivery system that is configured to receive a plurality of disks containing the solid material and provide these disks into an injector. The injector heats the disks to produce a gas or vapor that is then provided into a chamber. The sterilization process can be done by gas or vapor alone, or in combination with plasma or ultra violet radiation. In particular, a control system automatically induces the delivery system to provide the injector with a disk and then remove the disk once the injection sequence is complete.
摘要翻译: 从固体材料输送气体/蒸汽的系统。 具体地,用于使用从固体材料如非水/固体过氧化氢络合物释放的气体或蒸汽的输送系统。 该系统包括配送系统,该配送系统被配置为接收包含固体材料的多个盘,并将这些盘提供到喷射器中。 喷射器加热盘以产生气体或蒸气,然后将其提供到室中。 灭菌过程可以通过单独的气体或蒸气,或与等离子体或紫外线辐射结合进行。 特别地,控制系统自动地引导传送系统以向注射器提供磁盘,然后一旦注射顺序完成就移除磁盘。
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6.
公开(公告)号:US5820841A
公开(公告)日:1998-10-13
申请号:US716055
申请日:1996-09-19
申请人: Xiaolan Chen , Paul Taylor Jacobs , Szu-Min Lin
发明人: Xiaolan Chen , Paul Taylor Jacobs , Szu-Min Lin
IPC分类号: A61L2/16 , A01N59/00 , A61L2/20 , C01B15/04 , C01B15/055 , C01B15/06 , C01B15/14 , C01B15/16 , C01B15/08
摘要: A method of making an inorganic salt-hydrogen peroxide complex includes the following steps: (a) mixing the inorganic salt with sufficient water for a time sufficient to form a soft paste, (b) mixing the paste with an aqueous hydrogen peroxide solution to form a hydrogen peroxide-containing paste, and (c) drying the hydrogen peroxide-containing paste. A hydrate method of making Na.sub.4 P.sub.2 O.sub.7.3H.sub.2 O.sub.2 includes the steps of: mixing sodium pyrophosphate decahydrate solid with an aqueous solution of hydrogen peroxide having a concentration of less than 30%, and drying the mixture. Compositions of matter include K.sub.2 HPO.sub.4.3H.sub.2 O.sub.2, KH.sub.2 PO.sub.4.H.sub.2 O.sub.2 Ca.sub.2 P.sub.2 O.sub.7.nH.sub.2 O.sub.2, Ca.sub.2 P.sub.2 O.sub.4.nH.sub.2 O.sub.2, Na.sub.2 SO.sub.4.nH.sub.2 O.sub.2, K.sub.2 SO.sub.4.nH.sub.2 O.sub.2, Na.sub.2 SiO.sub.3.nH.sub.2 O.sub.2 and Na.sub.2 SiO.sub.7.nH.sub.2 O.sub.2.
摘要翻译: 制备无机盐 - 过氧化氢络合物的方法包括以下步骤:(a)将无机盐与足够的水混合足以形成软糊剂的时间,(b)将糊料与过氧化氢水溶液混合以形成 含有过氧化氢的糊剂,(c)干燥含过氧化氢的糊剂。 制备Na4P2O7.3H2O2的水合物方法包括以下步骤:将焦磷酸十水合物固体与浓度小于30%的过氧化氢水溶液混合,并干燥该混合物。 物质组成包括K2HPO4.3H2O2,KH2PO4H2O2 Ca2P2O7.nH2O2,Ca2P2O4.nH2O2,Na2SO4·nH2O2,K2SO4·nH2O2,Na2SiO3·nH2O2和Na2SiO7·nH2O2。
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公开(公告)号:US5667753A
公开(公告)日:1997-09-16
申请号:US549425
申请日:1995-10-27
申请人: Paul Taylor Jacobs , Szu-Min Lin , Xiaolan Chen
发明人: Paul Taylor Jacobs , Szu-Min Lin , Xiaolan Chen
IPC分类号: A61L2/16 , A01N59/00 , A61L2/04 , A61L2/10 , A61L2/14 , A61L2/20 , A61L2/24 , A61L2/26 , B01J7/00 , B65D65/38 , B65D65/40 , B65D81/24 , C01B15/01 , C01B15/03 , C01B15/037 , C01B15/06 , C01B15/08 , C01B15/10 , C01B15/14 , C01B15/16 , C01D7/00 , C07D233/64 , A61L9/00
CPC分类号: A61L2/208 , A01N59/00 , A61L2/14 , A61L2/20 , A61L2/26 , C01B15/01 , C01B15/03 , C01B15/06 , C01B15/08 , C01B15/103 , C01B15/14 , C01B15/16 , A61L2202/122 , A61L2202/24 , Y10S261/65 , Y10T428/1352 , Y10T428/1355 , Y10T428/1359 , Y10T428/1376 , Y10T428/1379 , Y10T428/1383
摘要: An apparatus and process for hydrogen peroxide vapor sterilization of medical instruments and similar devices make use of hydrogen peroxide vapor released from an inorganic hydrogen peroxide complex. The peroxide vapor can be released at room temperature and atmospheric pressure; however, the pressure used can be less than 50 torr and the temperature greater than 86.degree. C. to facilitate the release of hydrogen peroxide vapor. The heating rate can be greater than 5.degree. C. Optionally, a plasma can be used in conjunction with the vapor.
摘要翻译: 用于医疗器械和类似装置的过氧化氢蒸气灭菌的装置和方法利用从无机过氧化氢络合物释放的过氧化氢蒸气。 过氧化物蒸汽可以在室温和大气压下释放; 然而,使用的压力可以小于50托,并且温度大于86℃以促进过氧化氢蒸气的释放。 加热速率可以大于5℃。任选地,等离子体可以与蒸气结合使用。
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公开(公告)号:US07294305B2
公开(公告)日:2007-11-13
申请号:US11119605
申请日:2005-04-29
申请人: Szu-Min Lin , Paul Taylor Jacobs
发明人: Szu-Min Lin , Paul Taylor Jacobs
IPC分类号: A61L2/20
CPC分类号: A61L2/208 , A61L2/14 , A61L2/16 , A61L2202/122
摘要: A method and an apparatus for sterilizing a lumen device. A lumen and a container having an interface on a wall of the container are enclosed in a chamber. The lumen is placed across the interface so that one end of the lumen is in the container and the other end is in the chamber. Germicide is introduced into the chamber, and a pressure difference is created between the two ends of the lumen, so that the germicide flows through the lumen. The lumen may alternatively be placed across an interface which separates the chamber into two areas. Germicide is introduced into the chamber, and a pressure difference is created between the two areas of the chamber, causing the germicide to flow through the lumen.
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公开(公告)号:US06224828B1
公开(公告)日:2001-05-01
申请号:US09409964
申请日:1999-09-30
申请人: Szu-Min Lin , Paul Taylor Jacobs
发明人: Szu-Min Lin , Paul Taylor Jacobs
IPC分类号: A61L200
CPC分类号: A61L2/186 , A61L2/208 , A61L2202/122 , A61L2202/24
摘要: A method for sterilizing the interior and the exterior of a lumen device in a multi-chambered compartment with an interface with an adjustable opening in the interface. The lumen is placed partly in the first chamber and partly in the second chamber across the interface, sterilant is introduced into the multi-chambered compartment, and a flow is created between the two chambers through the lumen. The adjustable interface may be equipped with expandable material, compressible material, or inflatable material. Hydrogen peroxide or peracetic acid are suitable sterilants.
摘要翻译: 一种用于在具有与界面中的可调开口的界面的多室隔室中的管腔装置的内部和外部消毒的方法。 管腔部分放置在第一腔室中,部分放置在穿过界面的第二腔室中,灭菌剂被引入多室隔室中,并且通过管腔在两个腔室之间产生流动。 可调接口可以配备可膨胀材料,可压缩材料或可充气材料。 过氧化氢或过乙酸是合适的灭菌剂。
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公开(公告)号:US06319480B1
公开(公告)日:2001-11-20
申请号:US09643336
申请日:2000-08-22
IPC分类号: A61L220
CPC分类号: A61L2/186 , A61L2/14 , A61L2/16 , A61L2/208 , A61L2202/122 , A61L2202/24 , Y10S220/913 , Y10S422/906
摘要: A sterilized article is within the interior of a diffusion-restricted container. The container substantially prevents entry of microorganisms into the interior thereof. The container has at least one entry/exit port which permits entry/exit of gas and/or vapor into/out of the interior, but prevents entry of microorganisms into the interior.
摘要翻译: 无菌制品在扩散限制容器的内部。 容器基本上防止微生物进入其内部。 容器具有至少一个入口/出口,其允许气体和/或蒸气进入/离开内部,但是防止微生物进入内部。
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