公开(公告)号：US06334676B1

公开(公告)日：2002-01-01

申请号：US09065283

申请日：1998-04-23

Applicant: Linda A. Kaszczuk ,  David L. Cole ,  Xin Wen ,  Richard A. Landholm ,  Anthony R. Lubinsky

Inventor： Linda A. Kaszczuk ,  David L. Cole ,  Xin Wen ,  Richard A. Landholm ,  Anthony R. Lubinsky

IPC: B41J217

CPC classification number: C09D11/30 ,  B41J2/175 ,  B41J2/211 ,  B41J2/2114 ,  B41J3/4071 ,  B41J3/4075 ,  B41M1/14 ,  C09D11/40 ,  C09D11/54

Abstract: In a method for microfluidic printing of colored images on a receiver, including providing a first set of reservoirs containing colorant precursors for different colors; providing at least one reservoir containing a reactant; and reacting the colorant precursors and reactant(s) to provide colored pixels of the desired colors.

Abstract translation: 在用于接收器上彩色图像的微流体印刷的方法中，包括提供包含用于不同颜色的着色剂前体的第一组储存器; 提供包含反应物的至少一个储存器; 并使着色剂前体和反应物反应以提供所需颜色的着色像素。

公开(公告)号：US6097406A

公开(公告)日：2000-08-01

申请号：US84617

申请日：1998-05-26

Applicant: Anthony R. Lubinsky ,  Linda A. Kaszczuk ,  Xin Wen ,  David L. Cole ,  Richard A. Landholm

Inventor： Anthony R. Lubinsky ,  Linda A. Kaszczuk ,  Xin Wen ,  David L. Cole ,  Richard A. Landholm

IPC: B41J2/21 ,  B41J2/205

CPC classification number: B41J2/211

Abstract: An inkjet printing apparatus for printing continuous tone images on a receiver in response to a digital image, including a structure defining a plurality of colorant or colorant precursor receiving chambers, and another structure defining at least one mixing chamber for receiving a plurality of microdrops of colorants or colorant precursors from the colorant or colorant precursor receiving chambers to produce a desired colorant. The apparatus further includes a microdrop nozzle for each receiving chamber and in communication with the mixing chamber and a printing nozzle for each mixing chamber for causing a mixed drop to be delivered to the receiver. Further, the ejection of the desired number of microdrops is controlled and in response to the digital image and connected to the receiving chamber and the mixing chamber and for causing the desired number of microdrops to be ejected into the mixing chamber and then ejecting a mixed drop of colorant from the mixing chamber through the printing nozzle to the receiver.

Abstract translation: 一种用于响应于数字图像在接收机上打印连续色调图像的喷墨打印设备，包括限定多个着色剂或着色剂前体接收室的结构，以及限定用于接收多个着色剂微滴的至少一个混合室的另一结构 或着色剂前体从着色剂或着色剂前体接收室产生所需的着色剂。 该装置还包括用于每个接收室并与混合室连通的微滴喷嘴和用于每个混合室的印刷喷嘴，用于使混合液滴输送到接收器。 此外，控制所需数量的微滴的喷射，并且响应于数字图像并连接到接收室和混合室，并且使所需数量的微滴喷射到混合室中，然后喷射混合液滴 的着色剂从混合室通过印刷喷嘴到接收器。

公开(公告)号：US06046822A

公开(公告)日：2000-04-04

申请号：US4791

申请日：1998-01-09

Applicant: Xin Wen ,  Douglas W. Couwenhoven ,  Anthony R. Lubinsky

Inventor： Xin Wen ,  Douglas W. Couwenhoven ,  Anthony R. Lubinsky

IPC: B41J2/01 ,  B41J2/05 ,  B41J2/12 ,  B41J2/21 ,  H04N1/047 ,  H04N1/40 ,  H04N1/401 ,  G06F15/00

CPC classification number: B41J2/04573 ,  B41J2/0458 ,  B41J2/04588 ,  B41J2/0459 ,  B41J2/04591 ,  B41J2/2132 ,  H04N1/047 ,  H04N1/40031 ,  H04N1/4015 ,  H04N2201/04781

Abstract: Ink jet printing apparatus and method for improved accuracy of ink droplet placement on a receiver medium by compensating for jet direction variabilities between ink nozzles. More specifically, the invention is an ink jet printing apparatus and method for printing an output image on a receiver medium in response to an input image file having a plurality of pixels. The apparatus includes a print head and a nozzle integrally attached to the print head. The nozzle has a droplet placement characteristic (e.g., undesired placement of the droplet on the receiver medium) associated therewith. A waveform generator associated with the nozzle generates an electronic waveform including a plurality of electronic pulses to be supplied to the nozzle for adjusting the droplet placement characteristic. In this manner, the invention compensates for the undesired droplet placement characteristic, so that the droplet is accurately placed on the receiver medium irrespective of physical variabilities between nozzles.

Abstract translation: 喷墨打印装置和方法，用于通过补偿墨喷嘴之间的喷射方向变化来提高墨滴在接收介质上的放置精度。 更具体地，本发明是一种用于响应于具有多个像素的输入图像文件在接收介质上打印输出图像的喷墨打印设备和方法。 该设备包括打印头和整体连接到打印头的喷嘴。 喷嘴具有与其相关联的液滴放置特性（例如，不期望的接触介质上的液滴放置）。 与喷嘴相关联的波形发生器产生电子波形，该波形包括多个电子脉冲，供给喷嘴以调整液滴放置特性。 以这种方式，本发明补偿不期望的液滴放置特性，使得液滴精确地放置在接收器介质上，而与喷嘴之间的物理变化无关。

公开(公告)号：US6033059A

公开(公告)日：2000-03-07

申请号：US40121

申请日：1998-03-17

Applicant: Xin Wen ,  Anthony R. Lubinsky

Inventor： Xin Wen ,  Anthony R. Lubinsky

IPC: B41J2/045 ,  B41J2/055 ,  B41J2/14

CPC classification number: B41J2/04581 ,  B41J2/04588 ,  B41J2/14209 ,  B41J2202/10

Abstract: Printer apparatus and method. The apparatus includes a substrate having a plurality of spaced-apart pairs of selectively actuatable side walls defining respective channels therebetween of different depths. Each channel receives an associated one of a plurality of ink bodies therein and the substrate is formed of piezoelectric material responsive to electric stimuli. The pairs of side walls are preferably separated one from another by means of an intervening cut-out for reducing mechanical coupling between the ink channels. A cover plate is connected to the substrate and has a plurality of orifices therethrough in registration with respective ones of the channels such that the orifices are off-set one from another. Accordingly, in one embodiment of the invention, the channels have different depths and, therefore, the orifices, which are in registration with the channels, are off-set one from another to accommodate the different depths of the channels. A selected ink channel, which belongs to a first group of channels having a first predetermined depth, pressurize as its pairs of side walls are actuated. Also, a non-selected ink channel, which belongs to a second group of channels having a second predetermined depth, remains unpressurized as the selected channel is actuated. Moreover, the two groups of channels are interleaved. The channels of the first group are actuated at a later time that the channels of the second group as the printhead traverses a receiver medium. This feature of the invention reduces mechanical and hydraulic coupling between channels because actuation of selected channels belonging the two groups are spaced-apart in time.

Abstract translation: 打印机设备及方法 该装置包括具有多个间隔开的可选择性致动侧壁对的基板，其在不同深度之间限定相应的通道。 每个通道在其中接收多个墨体中相关联的一个墨体，并且该基底由响应于电刺激的压电材料形成。 优选地，通过用于减少墨水通道之间的机械联接的中间切口，一对侧壁彼此分离。 盖板连接到基板，并且具有多个通孔，与相应的通道对准，使得孔彼此偏移。 因此，在本发明的一个实施例中，通道具有不同的深度，因此，与通道对准的孔彼此偏离，以适应通道的不同深度。 属于具有第一预定深度的第一组通道的选定油墨通道被致动作为其对侧壁加压。 此外，属于具有第二预定深度的第二组通道的未选择的油墨通道在所选择的通道被致动时保持未加压。 此外，两组信道被交织。 稍后，第一组的通道被致动，当打印头的第二组的通道穿过接收器介质时。 本发明的该特征减少了通道之间的机械和液压耦合，因为属于两组的选定通道的致动在时间上是分开的。

公开(公告)号：US11110176B2

公开(公告)日：2021-09-07

申请号：US15821671

申请日：2017-11-22

Applicant: Xin Wen

Inventor： Xin Wen

IPC: A61K47/42 ,  C12N9/96 ,  C12N1/04 ,  A01N1/02 ,  A61K38/28

Abstract: Embodiments of the disclosure pertain to compositions containing (i) one or more non-antifreeze proteins or cell components or cells and (ii) one or more antifreeze proteins (AFPs), mimetics thereof, and/or analogs thereof, and a method of stabilizing a biologic (e.g., a protein, microbe, cell component or cell) against temperature stress and aggregation. The AFP may be selected from known antifreeze polypeptides and antifreeze peptides, analogs and mimetics of antifreeze proteins, active fragments of such antifreeze proteins, polypeptide and peptide mimetics, antifreeze peptoids and polymers, and combinations thereof. The non-antifreeze protein, cell component or cell comprises a known protein, cell component or cell used in the pharmaceutical, medical, agricultural, veterinary and/or food industry(ies). The AFP protects the function of the non-antifreeze protein, microbe(s), cell component(s) or cell(s) under temperature stress (e.g., a temperature of −20-60° C.).

公开(公告)号：US08082053B2

公开(公告)日：2011-12-20

申请号：US11935320

申请日：2007-11-05

Applicant: Xin Wen ,  Russ Ennio Muzzolini ,  Jeff D. Boone

Inventor： Xin Wen ,  Russ Ennio Muzzolini ,  Jeff D. Boone

IPC: G06F19/00

CPC classification number: G05B19/41865 ,  G05B2219/25182 ,  G05B2219/32263 ,  G06Q10/06 ,  Y02P90/20

Abstract: An automated manufacturing system comprises a computer processing system and a plurality of consolidation systems. The computer processing system receives information on product subbatches and product packages and consolidation status information to produce consolidation assignment information, each product package comprising one or more product subbatches. The consolidation systems receive the product subbatches in accordance to the consolidation assignment information and consolidate the product subbatches into product packages, wherein the status of the consolidation systems are tracked and the consolidation status information is sent to the computer processing system.

Abstract translation: 自动化制造系统包括计算机处理系统和多个合并系统。 计算机处理系统接收关于产品子批和产品包和合并状态信息的信息以产生合并分配信息，每个产品包包括一个或多个产品子批。 整合系统根据合并分配信息接收产品子批次，并将产品子批次合并到产品包中，其中跟踪合并系统的状态，并将合并状态信息发送到计算机处理系统。

公开(公告)号：US20100331369A1

公开(公告)日：2010-12-30

申请号：US12817773

申请日：2010-06-17

Applicant: Qun Sun ,  Xin Wen

Inventor： Qun Sun ,  Xin Wen

IPC: A61K31/444 ,  A61P29/00

CPC classification number: A61K31/444 ,  C07D401/04 ,  C07D401/14 ,  C07D413/14 ,  C07D417/04 ,  C07D417/14

Abstract: A compound of formula: where Ar1, Ar2, X, R3, and m are as disclosed herein or a pharmaceutically acceptable salt thereof (a “Cycloheteroalkenyl Compound”); compositions comprising an effective amount of a Cycloheteroalkenyl Compound; and methods for treating or preventing pain, UI, an ulcer, IBD, IBS, an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy, stroke, a seizure, a pruritic condition, psychosis, a cognitive disorder, a memory deficit, restricted brain function, Huntington's chorea, amyotrophic lateral sclerosis, dementia, retinopathy, a muscle spasm, a migraine, vomiting, dyskinesia, or depression in an animal comprising administering to an animal in need thereof an effective amount of a Cycloheteroalkenyl Compound are disclosed herein.

Abstract translation: 式中的化合物：其中Ar1，Ar2，X，R3和m如本文所公开或其药学上可接受的盐（“环烯基烯基化合物”）; 包含有效量的环烯基烯基化合物的组合物; 以及用于治疗或预防疼痛，UI，溃疡，IBD，IBS，成瘾性障碍，帕金森病，帕金森综合征，焦虑，癫痫，中风，癫痫发作，瘙痒症状，精神病，认知障碍，记忆缺陷，受限制 脑功能，亨廷顿舞蹈病，肌萎缩性侧索硬化，痴呆，视网膜病变，肌肉痉挛，偏头痛，呕吐，运动障碍或抑郁症，包括向有需要的动物施用有效量的环烯基烯基化合物。

公开(公告)号：US20090287585A1

公开(公告)日：2009-11-19

申请号：US12476886

申请日：2009-06-02

Applicant: Peter Charles Elarde ,  Patrick C. Teo ,  Russ Ennio Muzzolini ,  Jeannine Marie Smith ,  Xin Wen

Inventor： Peter Charles Elarde ,  Patrick C. Teo ,  Russ Ennio Muzzolini ,  Jeannine Marie Smith ,  Xin Wen

IPC: G06Q30/00 ,  G06Q50/00

CPC classification number: B42D5/04 ,  B42D15/045 ,  G06Q30/0601

Abstract: A method for producing a gift card for a gift imaging product, comprises receiving an order of the gift imaging product from a user, producing the gift imaging product, producing the gift card by the user for the gift imaging product; and consolidating the gift card with the gift imaging product into one package.

Abstract translation: 一种用于制作礼物成像产品的礼品卡的方法，包括从用户接收礼品成像产品的订单，产生礼品成像产品，由用户为礼物成像产品生产礼品卡; 并将礼品卡与礼品成像产品整合成一个包装。

公开(公告)号：US20080288521A1

公开(公告)日：2008-11-20

申请号：US11935320

申请日：2007-11-05

Applicant: Xin Wen ,  Russ Ennio Muzzolini ,  Jeff D. Boone

Inventor： Xin Wen ,  Russ Ennio Muzzolini ,  Jeff D. Boone

IPC: G06F17/30

CPC classification number: G05B19/41865 ,  G05B2219/25182 ,  G05B2219/32263 ,  G06Q10/06 ,  Y02P90/20

Abstract: An automated manufacturing system comprises a computer processing system and a plurality of consolidation systems. The computer processing system receives information on product subbatches and product packages and consolidation status information to produce consolidation assignment information, each product package comprising one or more product subbatches. The consolidation systems receive the product subbatches in accordance to the consolidation assignment information and consolidate the product subbatches into product packages, wherein the status of the consolidation systems are tracked and the consolidation status information is sent to the computer processing system.

Abstract translation: 自动化制造系统包括计算机处理系统和多个合并系统。 计算机处理系统接收关于产品子批和产品包和合并状态信息的信息以产生合并分配信息，每个产品包包括一个或多个产品子批。 整合系统根据合并分配信息接收产品子批次，并将产品子批次合并到产品包中，其中跟踪合并系统的状态，并将合并状态信息发送到计算机处理系统。

公开(公告)号：US07437024B2

公开(公告)日：2008-10-14

申请号：US10962933

申请日：2004-10-12

Applicant: Daniel R. Baum ,  Xin Wen

Inventor： Daniel R. Baum ,  Xin Wen

IPC: G06K9/03 ,  G06Q30/00

CPC classification number: G06Q30/0641 ,  G03D15/005 ,  H04N1/60 ,  H04N1/6086

Abstract: A method for personalizing an image-based physical manifestation to conform with user preferences for image processing. In one implementation, the method includes identifying an image for processing, identifying user preferences for image processing and processing the image including manipulating image data for the image in accordance with the user preferences.

Abstract translation: 一种用于个性化基于图像的物理表现以符合图像处理的用户偏好的方法。 在一个实现中，该方法包括识别用于处理的图像，识别用于图像处理的用户偏好并且处理该图像，包括根据用户偏好来操纵图像的图像数据。