公开(公告)号：US20130065233A1

公开(公告)日：2013-03-14

申请号：US13581971

申请日：2011-03-02

申请人： Xiyu Jia ,  Onyinyechi Chimaokereke ,  Lam Nguyen

发明人： Xiyu Jia ,  Onyinyechi Chimaokereke ,  Lam Nguyen

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6827 ,  C12Q2545/114 ,  C12Q2521/331

摘要： In a first aspect, the invention concerns a method for detecting or quantifying DNA methylation at a locus. In one embodiment, a methylation-sensitive endonuclease is formulated together with a polymerase enzyme in an appropriate reaction mixture such that amplification of DNA occurs in a methylation specific manor. Quantitative DNA amplification at selected loci can be used to determine the level of methylation. Kits and reagents for performing such methods are also provided.

摘要翻译： 在第一方面，本发明涉及用于检测或定量某个位点DNA甲基化的方法。 在一个实施方案中，将甲基化敏感型核酸内切酶与聚合酶​​一起配制在合适的反应混合物中，使DNA的扩增发生在甲基化特异性庄园中。 选择位点的定量DNA扩增可用于测定甲基化水平。 还提供了用于执行这些方法的试剂盒和试剂。

公开(公告)号：US09642623B2

公开(公告)日：2017-05-09

申请号：US13640467

申请日：2011-04-15

申请人： Jayant P. Agarwal ,  Bruce K. Gale ,  Lam Nguyen ,  Cory Shorr ,  Brian Stauffer ,  Cody Lee Gehrke

发明人： Jayant P. Agarwal ,  Bruce K. Gale ,  Lam Nguyen ,  Cory Shorr ,  Brian Stauffer ,  Cody Lee Gehrke

IPC分类号： A61B17/11 ,  A61B17/00

CPC分类号： A61B17/11 ,  A61B2017/00004 ,  A61B2017/00349 ,  A61B2017/00477 ,  A61B2017/00867 ,  A61B2017/00893 ,  A61B2017/1103 ,  A61B2017/1107 ,  A61B2017/1121 ,  A61B2017/1125 ,  A61B2017/1132

摘要： Methods, devices, apparatus, assemblies, and kits for performing a vascular anastomosis are disclosed. A device for a vascular anastomosis includes tissue engaging portions that can move between at least two configurations. In some embodiments, the tissue engaging portions move without the aid of moving parts, while in other embodiments the tissue engaging portions extend from one or more movable wings. The tissue engaging portions may be separated by a first distance when in a pre-deployment configuration and by a second distance when in a deployed configuration. A method includes engaging a plurality of tissue engaging members of a coupling device against first end tissue. After selectively engaging the tissue engaging members and first end tissue, the first end tissue is stretched by at least moving the tissue engaging members. The stretched first end tissue is coupled to the second end tissue by mating the coupling device to a mating anastomosis device.

公开(公告)号：US08099962B2

公开(公告)日：2012-01-24

申请号：US12325009

申请日：2008-11-28

申请人： Eric Durocher ,  John Pietrobon ,  Lam Nguyen

发明人： Eric Durocher ,  John Pietrobon ,  Lam Nguyen

IPC分类号： F02C7/20 ,  F01D25/16

CPC分类号： F01D9/065 ,  F01D25/162 ,  F01D25/243 ,  F01D25/28 ,  F05B2260/301 ,  F05D2230/60 ,  F05D2240/11 ,  F05D2240/55 ,  F05D2260/94 ,  Y10T29/4932

摘要： A gas turbine engine has a casing component, such as a mid turbine frame system, which includes an outer case surrounding a spoke or strut casing. Load transfer spokes of the spoke casing are detachably connected to the outer case and radially extend between the outer case and an inner case of the spoke casing. A bearing housing is supported by the inner case of the spoke casing. An arrangement for radially centring the bearing within the outer case is provided, the arrangement including at least three radial locators mounted to the outer case.

摘要翻译： 燃气涡轮发动机具有诸如中间涡轮机框架系统的壳体部件，其包括围绕辐条或支柱壳体的外壳。 轮辐壳体的负载传送轮辐可拆卸地连接到外壳，并且在外壳和轮辐壳体的内壳之间径向延伸。 轴承壳体由轮辐壳体的内壳体支撑。 提供了用于使轴承在外壳内径向对中的布置，该装置包括安装到外壳的至少三个径向定位器。

公开(公告)号：US20110081240A1

公开(公告)日：2011-04-07

申请号：US12571802

申请日：2009-10-01

申请人： Eric Durocher ,  Lam Nguyen

发明人： Eric Durocher ,  Lam Nguyen

IPC分类号： F01D9/04

CPC分类号： F01D9/044 ,  F05D2230/232 ,  F05D2230/237

摘要： A static vane ring for gas turbine engines includes a plurality of radial struts extending between and interconnecting outer and inner duct walls which define an annular duct therebetween. A load transfer apparatus is attached to at least one of the outer and inner duct walls to transfer load from vane to ring, and between vanes.

摘要翻译： 用于燃气涡轮发动机的静态叶片环包括在内壁和内壁之间延伸的多个径向支柱，其在其间限定了环形管道。 负载传送装置附接到外管壁和内管壁中的至少一个，以将负载从叶片传递到环，并且在叶片之间。

公开(公告)号：US20070112692A1

公开(公告)日：2007-05-17

申请号：US11553629

申请日：2006-10-27

申请人： Cindy Bolduc ,  Miguel Carrasco ,  Bob Green ,  Lam Nguyen ,  Lyle Mustard ,  Mike Nicholson ,  Suresh Jayaraman ,  Rachelle Thibodeau

发明人： Cindy Bolduc ,  Miguel Carrasco ,  Bob Green ,  Lam Nguyen ,  Lyle Mustard ,  Mike Nicholson ,  Suresh Jayaraman ,  Rachelle Thibodeau

IPC分类号： G06F17/00

CPC分类号： G06Q10/087 ,  G06F3/03545 ,  G06F3/041 ,  G06Q30/02 ,  G06Q30/0283 ,  G06Q30/06

摘要： A drawing take off system itemizes components shown on a paper drawing. The take off system includes a sleeve for holding a standard pen, a computer having a software module, and an interface connection between the sleeve and the computer. The software module maintains a list of each component model shown on the drawing. The sleeve includes a pen stroke switch for counting pen strokes and a component selection switch for selecting a component model from the component model list compiled in the software module. As an estimator marks components on the paper drawing, the take off system counts pen strokes for each individual component of each model of component marked on the paper project drawing by the estimator and calculates the cost for all of the components taken off of the paper drawing.

摘要翻译： 绘图起飞系统列出了图纸上显示的组件。 起飞系统包括用于保持标准笔的套筒，具有软件模块的计算机以及套筒和计算机之间的接口连接。 软件模块维护图纸上显示的每个组件模型的列表。 套筒包括用于计数笔划的笔触开关和用于从在软件模块中编译的组件模型列表中选择组件模型的组件选择开关。 作为评估者标记纸张上的组件，起飞系统计算由估计器在纸张项目图上标记的每个模型组件的每个单独组件的笔划，并计算从纸张中取出的所有组件的成本 。

公开(公告)号：US5267775A

公开(公告)日：1993-12-07

申请号：US776650

申请日：1991-10-03

申请人： Lam Nguyen

发明人： Lam Nguyen

IPC分类号： F16M13/02 ,  B60N2/90 ,  B60R11/00 ,  B60R11/02 ,  A47C7/62

CPC分类号： B60R11/0235 ,  B60N2/44 ,  B60R2011/0015 ,  B60R2011/0045 ,  B60R2011/0276

摘要： An automatic tilt mechanism for attaching a monitor to a movable structure, comprising: a hinge having a first leg means for attachment to a monitor, a second leg means for attachment to the movable structure and a pivot joining the first and second leg means so that they can be moved with respect to each other after attachment; a transfer means adapted to move in proportion to movement of the movable structure; and a connecting means for transmitting movement of the transfer means to the hinge so that the first leg means moves proportionally to movement of the movable structure. The invention may further include a reclinable seat back of a seat in a passenger vehicle as the movable structure. The invention may still further include a fixed length sheathed cable as the connecting means. The invention may also provide an automatic tilt mechanism that is driven by motion of the seat back.

摘要翻译： 一种用于将监视器附接到可移动结构的自动倾斜机构，包括：铰链，具有用于附接到监视器的第一腿部装置，用于附接到可移动结构的第二腿部装置和连接第一和第二腿部装置的枢轴，使得 附件后可以相互移动; 传送装置，其适于与所述可移动结构的移动成比例地移动; 以及用于将传送装置的运动传递到铰链的连接装置，使得第一腿部装置与可移动结构的运动成比例地移动。 本发明还可以包括作为可移动结构的乘客车辆中的座椅的可倾斜座椅靠背。 本发明还可以包括固定长度的护套电缆作为连接装置。 本发明还可以提供由座椅靠背的运动驱动的自动倾斜机构。

公开(公告)号：US20130204275A1

公开(公告)日：2013-08-08

申请号：US13640467

申请日：2011-04-15

申请人： Jayant P. Agarwal ,  Bruce K. Gale ,  Lam Nguyen ,  Cory Shorr ,  Brian Stauffer ,  Cody Lee Gehrke

发明人： Jayant P. Agarwal ,  Bruce K. Gale ,  Lam Nguyen ,  Cory Shorr ,  Brian Stauffer ,  Cody Lee Gehrke

IPC分类号： A61B17/11

CPC分类号： A61B17/11 ,  A61B2017/00004 ,  A61B2017/00349 ,  A61B2017/00477 ,  A61B2017/00867 ,  A61B2017/00893 ,  A61B2017/1103 ,  A61B2017/1107 ,  A61B2017/1121 ,  A61B2017/1125 ,  A61B2017/1132

摘要： Methods, devices, apparatus, assemblies, and kits for performing a vascular anastomosis are disclosed. A device for a vascular anastomosis includes tissue engaging portions that can move between at least two configurations. In some embodiments, the tissue engaging portions move without the aid of moving parts, while in other embodiments the tissue engaging portions extend from one or more movable wings. The tissue engaging portions may be separated by a first distance when in a pre-deployment configuration and by a second distance when in a deployed configuration. A method includes engaging a plurality of tissue engaging members of a coupling device against first end tissue. After selectively engaging the tissue engaging members and first end tissue, the first end tissue is stretched by at least moving the tissue engaging members. The stretched first end tissue is coupled to the second end tissue by mating the coupling device to a mating anastomosis device.

摘要翻译： 公开了用于执行血管吻合的方法，装置，装置，组件和试剂盒。 用于血管吻合的装置包括可在至少两种构型之间移动的组织接合部分。 在一些实施例中，组织接合部分不借助移动部分移动，而在其它实施例中，组织接合部分从一个或多个活动翼部延伸。 当处于部署前配置时，组织接合部分可以分开第一距离，并且当处于展开配置时，组织接合部分可以分开第一距离。 一种方法包括将耦合装置的多个组织接合构件抵靠第一端组织接合。 在选择性地接合组织接合构件和第一端部组织之后，通过至少移动组织接合构件来拉伸第一端部组织。 拉伸的第一端组织通过将联接装置配合到配合的吻合装置而联接到第二端组织。

公开(公告)号：US08061969B2

公开(公告)日：2011-11-22

申请号：US12325000

申请日：2008-11-28

申请人： Eric Durocher ,  John Pietrobon ,  Lam Nguyen

发明人： Eric Durocher ,  John Pietrobon ,  Lam Nguyen

IPC分类号： F01D1/24 ,  F01D13/00 ,  F03D3/02 ,  F04D13/04 ,  F04D25/16

CPC分类号： F01D9/065 ,  F01D21/045 ,  F01D21/08 ,  F01D25/162 ,  F01D25/28

摘要： A gas turbine engine mid turbine frame having an inner case supporting at least one bearing and at least three spokes extending radially outwardly to an outer case, the mid turbine frame having an interturbine duct extending through the mid turbine frame, the interturbine duct spaced axially closer to an upstream turbine disc than a bearing supporting structure of the mid turbine frame and mounted axially slidingly relative to the bearing supporting structure to substantially isolate the bearing supporting structure from axial loads, for example such as disc loads incurred in the unlikely event a turbine disc shaft shears within the engine.

摘要翻译： 一种燃气涡轮发动机中间涡轮机框架，其具有支撑至少一个轴承的内部壳体和至少三个径向向外延伸到外部壳体的轮辐，所述中间涡轮机框架具有延伸穿过所述中间涡轮机框架的涡轮机管道，所述涡轮机管道在轴向上更靠近 到中间涡轮机框架的轴承支撑结构的上游涡轮盘，并相对于轴承支撑结构轴向滑动地安装，以将轴承支撑结构与轴向载荷基本上隔离，例如在不太可能发生的涡轮盘 发动机内的轴剪。

公开(公告)号：US5477782A

公开(公告)日：1995-12-26

申请号：US414048

申请日：1995-03-30

申请人： Lam Nguyen

发明人： Lam Nguyen

IPC分类号： B41F9/06 ,  B41F31/02 ,  B41F9/10 ,  B41F31/04

CPC分类号： B41F31/027 ,  B41F9/065

摘要： Disclosed is an inking device for a photogravure printing apparatus, wherein the inking chamber is closed on all sides; it is filled with ink under pressure; it extends solely over the length of the engraved part of the cylinder, and it is defined, at its two longitudinal ends, by radial closure plates with curved peripheral surfaces which are applied against the smooth end part of the engraved cylinder, on either side of its useful engraved central part.

摘要翻译： 公开了一种用于照相凹版印刷设备的上墨装置，其中上墨室在所有侧面都是封闭的; 在压力下充满墨水; 它仅在圆柱体的雕刻部分的长度上延伸，并且在其两个纵向端部处由径向封闭板限定，该封闭板具有弯曲的周边表面，其被施加在雕刻圆柱体的平滑端部上， 其有用的雕刻中心部分。

公开(公告)号：US09291070B2

公开(公告)日：2016-03-22

申请号：US13309709

申请日：2011-12-02

申请人： Bruce Fielding ,  Assaf Farah ,  Karl D. Blume ,  Lam Nguyen ,  Theodore W Kapustka

发明人： Bruce Fielding ,  Assaf Farah ,  Karl D. Blume ,  Lam Nguyen ,  Theodore W Kapustka

IPC分类号： F01D25/00 ,  F01D21/04 ,  F01D5/02

CPC分类号： F01D21/045 ,  F01D5/02 ,  F01D5/026 ,  F01D5/06 ,  F01D5/066 ,  F05D2260/31

摘要： A gas turbine engine has a spool including compressor and turbine rotors connected by a first shaft. The first shaft extends concentrically around a second shaft. The first shaft forward end has a portion with an inner diameter of close tolerance with the second shaft. The second shaft has a region of enlarged diameter located axially aft of the compressor rotor but axially forward of the forward end of the first shaft. The region of enlarged diameter has a diameter greater than the inner diameter of the forward end portion of the first shaft to cause the region of enlarged diameter of the second shaft to engage the first shaft in interference in the event that the second shaft is moved axially aft relative to the first shaft more than a pre-selected axial distance.

摘要翻译： 燃气涡轮发动机具有包括压缩机的阀芯和通过第一轴连接的涡轮转子。 第一轴同心地围绕第二轴延伸。 第一轴前端具有与第二轴具有紧密公差的内径的部分。 第二轴具有位于压缩机转子的轴向后方的直径增大的区域，但轴向位于第一轴的前端的前方。 增大直径的区域的直径大于第一轴的前端部分的内径，以致在第二轴轴向移动的情况下，使第二轴的直径增大的区域与第一轴接合， 相对于第一轴的后部大于预选轴向距离。