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    Safe and versatile cloning vector
    2.
    发明授权
    Safe and versatile cloning vector 失效
    安全多功能的克隆载体

    公开(公告)号：US5290691A

    公开(公告)日：1994-03-01

    申请号：US814203

    申请日：1991-12-26

    申请人： Susumu Mitsuhashi ,  Matsuhisa Inoue ,  Masao Nagashima

    发明人： Susumu Mitsuhashi ,  Matsuhisa Inoue ,  Masao Nagashima

    IPC分类号： C12N15/75 ,  C12N15/78 ,  C12N15/00 ,  C12N15/11 ,  C12N15/70 ,  C12N15/74

    CPC分类号： C12N15/75 ,  C12N15/78

    摘要： A safe and versatile recombinant DNA cloning vector having at least two functionally different replication origins selected independently from the group consisting of a replication origin functional in Bacillus subtilis, a replication origin functional in Escherichia coli and a replication origin functional in Pseudomonas aeruginosa, and at least one DNA segment which provides resistance against at least one antibiotic after introduction into susceptible host cells. The origin for replication origin functional in Bacillus subtilis can be a restriction fragment of a plasmid of Gram positive bacteria, and that Escherichia coli or Pseudomonas aeruginosa can be a restriction fragment of a plasmid of Gram negative bacteria, e.g. a restriction fragment of plasmids pMS 140-1 or pMS 71.

    摘要翻译： 一种安全且通用的重组DNA克隆载体，其具有至少两个功能上不同的复制起点，其独立地选自在枯草芽孢杆菌中起作用的复制起点，在大肠杆菌中起作用的复制起点和在铜绿假单胞菌中起作用的复制起点，以及至少 一个DNA片段，其在引入易感宿主细胞后提供对至少一种抗生素的抗性。 在枯草芽孢杆菌中起作用的复制起点可以是革兰氏阳性细菌质粒的限制性片段，并且大肠杆菌或铜绿假单胞菌可以是革兰氏阴性细菌质粒的限制性片段，例如， 质粒pMS 140-1或pMS 71的限制性片段。

    Derivatives of antifungal substance BE-31405 and process for producing the same
    3.
    发明授权
    Derivatives of antifungal substance BE-31405 and process for producing the same 失效
    抗真菌物质BE-31405的衍生物及其制备方法

    公开(公告)号：US6087390A

    公开(公告)日：2000-07-11

    申请号：US423643

    申请日：1999-11-18

    申请人： Atsushi Hirano ,  Koichiro Torigoe ,  Hidenori Ogawa ,  Seigo Kamiya ,  Hiromasa Okada ,  Masao Nagashima ,  Katsuhisa Kojiri ,  Hiroyuki Suda

    发明人： Atsushi Hirano ,  Koichiro Torigoe ,  Hidenori Ogawa ,  Seigo Kamiya ,  Hiromasa Okada ,  Masao Nagashima ,  Katsuhisa Kojiri ,  Hiroyuki Suda

    IPC分类号： C07H15/18 ,  A61K31/35 ,  C07D311/02

    CPC分类号： C07H15/18

    摘要： The present invention relates to a compound represented by general formula (I) or a pharmaceutically acceptable salt or ester thereof: ##STR1## wherein each of R.sup.1 and R.sup.2 is independently a hydrogen atom, a C.sub.1 -C.sub.16 alkyl group, a C.sub.2 -C.sub.10 alkenyl group, a C.sub.3 -C.sub.6 alkynyl group, a C.sub.6 -C.sub.12 aryl group, a C.sub.7 -C.sub.15 aralkyl group or a heterocyclic group which is not substituted, a C.sub.1 -C.sub.16 alkyl group, a C.sub.2 -C.sub.10 alkenyl group, a C.sub.3 -C.sub.6 alkynyl group, a C.sub.6 -C.sub.12 aryl group, a C.sub.7 -C.sub.15 aralkyl group or a heterocyclic group which has substituent(s), or a group represented by --Y--R.sup.3 (provided that when R.sup.2 is a hydrogen atom, R.sup.1 is not a methyl group or an acetyl group; when R.sup.2 is an acetyl group, R.sup.1 is not a methyl group), an antifungal agent containing it as an active ingredient and an antifungal composition containing it and an azole type antifungal agent.

    摘要翻译： PCT No.PCT / JP98 / 02218 Sec。 371日期：1999年11月18日 102（e）1999年11月18日日期PCT提交1998年5月20日PCT公布。 第WO98 / 52957号公报 日本公开日1998年11月26日本发明涉及由通式（I）表示的化合物或其药学上可接受的盐或酯：其中R1和R2各自独立地为氢原子，C1-C16烷基，C2- C10链烯基，C3-C6炔基，C6-C12芳基，C7-C15芳烷基或未被取代的杂环基，C1-C16烷基，C2-C10链烯基，C3- C6炔基，C6-C12芳基，C7-C15芳烷基或具有取代基的杂环基，或由-Y-R3表示的基团（条件是当R2为氢原子时，R1不为 甲基或乙酰基;当R 2是乙酰基时，R 1不是甲基），含有它作为活性成分的抗真菌剂和含有它的抗真菌组合物和唑类抗真菌剂。

    Circuit for driving reel motor of videotape recorder
    5.
    发明授权
    Circuit for driving reel motor of videotape recorder 失效
    驱动录像机卷轴电机的电路

    公开(公告)号：US5291107A

    公开(公告)日：1994-03-01

    申请号：US887556

    申请日：1992-05-18

    申请人： Masao Nagashima

    发明人： Masao Nagashima

    IPC分类号： G11B15/46 ,  H02P7/285 ,  H02P7/00

    CPC分类号： G11B15/46 ,  H02P7/2855 ,  Y10S388/93

    摘要： A load driving circuit causes a driving current to flow through a load, such as a reel motor, an audio load or the like through the collector and emitter of a drive transistor. A load voltage which changes according to changes in the driving current is obtained at a point of connection between the drive transistor and the load. On the basis of the load voltage, an offset voltage having a predetermined constant value is generated in a power supplying circuit so as to cancel a change in the load voltage. The offset voltage is supplied as driving source output to the drive transistor so as to prevent the generation of excess heat in the drive transistor even if the driving current changes.

    摘要翻译： 负载驱动电路通过驱动晶体管的集电极和发射极使驱动电流流过诸如卷轴电机，音频负载等的负载。 在驱动晶体管和负载之间的连接点处获得根据驱动电流的变化而变化的负载电压。 基于负载电压，在供电电路中产生具有预定常数值的偏移电压，以消除负载电压的变化。 偏移电压作为驱动源输出被提供给驱动晶体管，以便即使驱动电流改变也能防止驱动晶体管中产生过多的热量。

    Method of manufacturing a blade wheel
    7.
    发明授权
    Method of manufacturing a blade wheel 失效
    制造叶轮的方法

    公开(公告)号：US4450611A

    公开(公告)日：1984-05-29

    申请号：US325015

    申请日：1981-11-25

    申请人： Hiroshi Ito ,  Toshihiko Yoshio ,  Masao Nagashima

    发明人： Hiroshi Ito ,  Toshihiko Yoshio ,  Masao Nagashima

    IPC分类号： F04D29/22 ,  B23P15/00 ,  F03B3/12 ,  F16H41/28 ,  B23P15/04 ,  B23K31/02

    CPC分类号： B23P15/006 ,  Y02E10/223 ,  Y02P70/525 ,  Y10T29/4933

    摘要： Method of manufacturing a blade wheel including setting a plurality of blades into a first jig, positioning an annular core member thereover with mating projections on the blades with slits on the core member, welding at the mating points, setting the sub-assembly thus produced onto a shell member held in another jig with claw members of the blades engaging peripherally located slots in the shell member, and securing the two together with an annular retainer member with grooves engaging other claw members on the blades being spot welded to the shell member.

    摘要翻译： 一种制造叶轮的方法，包括将多个叶片设置到第一夹具中，将环形芯部件定位在其上，并且在芯部件上具有切口的叶片上的配合突起，在配合点处焊接，将如此产生的子组件设置到 保持在另一个夹具中的外壳构件，其中叶片的爪构件接合在壳构件中的外围定位的狭槽，并且将两者固定在一起，其中环形保持构件具有与叶片上的其他爪构件接合点焊接到壳构件上的凹槽。