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92 条记录 (耗时 0.039 秒)

    9a, 11-3C-bicyclic 9a-azalide derivatives
    1.
    发明授权
    9a, 11-3C-bicyclic 9a-azalide derivatives 有权
    9a，11-3C-双环9a-氮杂衍生物

    公开(公告)号：US07276487B2

    公开(公告)日：2007-10-02

    申请号：US10946339

    申请日：2004-09-21

    申请人： Guoqiang Wang ,  Yulin Peng ,  Yanchun Wang ,  Ly Tam Phan ,  Yat Sun Or

    发明人： Guoqiang Wang ,  Yulin Peng ,  Yanchun Wang ,  Ly Tam Phan ,  Yat Sun Or

    IPC分类号： A61K31/70 ,  C07H17/08

    CPC分类号： C07H17/08

    摘要： The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

    摘要翻译： 本发明公开了式I化合物或其药学上可接受的盐，酯或前药：其表现出抗菌性质。 本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。 本发明还包括制备本发明化合物的方法。

    6-11 Bridged Oxime Erythromycin Derivatives
    2.
    发明申请
    6-11 Bridged Oxime Erythromycin Derivatives 审中-公开
    6-11桥接肟红霉素衍生物

    公开(公告)号：US20100041618A1

    公开(公告)日：2010-02-18

    申请号：US12543155

    申请日：2009-08-18

    申请人： Guoqiang Wang ,  Ly Tam Phan ,  Yat Sun Or ,  Yao-Ling Qiu ,  Deqiang Niu ,  Yulin Peng ,  Marina Busuyek ,  Yanchun Wang ,  Suanne Nakajima

    发明人： Guoqiang Wang ,  Ly Tam Phan ,  Yat Sun Or ,  Yao-Ling Qiu ,  Deqiang Niu ,  Yulin Peng ,  Marina Busuyek ,  Yanchun Wang ,  Suanne Nakajima

    IPC分类号： A61K31/7048 ,  C07H17/08

    CPC分类号： C07H17/08

    摘要： The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes processes by which to make the compounds of the present invention.

    摘要翻译： 本发明公开了式I化合物或其药学上可接受的盐，酯或前药：其表现出抗菌性质。 本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。 本发明还包括制备本发明化合物的方法。

    6-11 Bridged Oxime Erythromycin Derivatives
    3.
    发明申请
    6-11 Bridged Oxime Erythromycin Derivatives 审中-公开
    6-11桥接肟红霉素衍生物

    公开(公告)号：US20080262208A1

    公开(公告)日：2008-10-23

    申请号：US12123874

    申请日：2008-05-20

    申请人： Guoqiang Wang ,  Ly Tam Phan ,  Yat Sun Or ,  Yao-Ling Qiu ,  Deqiang Niu ,  Yulin Peng ,  Marina Busuyek ,  Yanchun Wang ,  Suanne Nakajima

    发明人： Guoqiang Wang ,  Ly Tam Phan ,  Yat Sun Or ,  Yao-Ling Qiu ,  Deqiang Niu ,  Yulin Peng ,  Marina Busuyek ,  Yanchun Wang ,  Suanne Nakajima

    IPC分类号： C07H17/08

    CPC分类号： C07H17/08

    摘要： The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes processes by which to make the compounds of the present invention.

    摘要翻译： 本发明公开了式I化合物或其药学上可接受的盐，酯或前药：其表现出抗菌性质。 本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。 本发明还包括制备本发明化合物的方法。

    9A, 11-2C-bicyclic 9a-azalide derivatives
    5.
    发明授权
    9A, 11-2C-bicyclic 9a-azalide derivatives 有权
    9A，11-2C-双环9a-氮杂环戊二烯衍生物

    公开(公告)号：US07271155B2

    公开(公告)日：2007-09-18

    申请号：US11324502

    申请日：2006-01-03

    申请人： Yat Sun Or ,  Ly Tam Phan ,  Guoqiang Wang ,  Yanchun Wang ,  Yulin Peng

    发明人： Yat Sun Or ,  Ly Tam Phan ,  Guoqiang Wang ,  Yanchun Wang ,  Yulin Peng

    IPC分类号： A61K31/70 ,  C07H17/08

    CPC分类号： C07H17/08

    摘要： The present invention discloses compounds of formulae I and II, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

    摘要翻译： 本发明公开了式I和II的化合物或其药学上可接受的盐，酯或前药：其表现出抗菌性质。 本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。 本发明还包括制备本发明化合物的方法。

    6,11-bridged biaryl macrolides
    8.
    发明授权
    6,11-bridged biaryl macrolides 有权
    6,11桥接的联芳基大环内酯类

    公开(公告)号：US08354383B2

    公开(公告)日：2013-01-15

    申请号：US12399801

    申请日：2009-03-06

    申请人： In Jong Kim ,  Tongzhu Liu ,  Jiang Long ,  Guoqiang Wang ,  Yao-Ling Qiu ,  Heejin Kim ,  Yanchun Wang ,  Ly Tam Phan ,  Yat Sun Or

    发明人： In Jong Kim ,  Tongzhu Liu ,  Jiang Long ,  Guoqiang Wang ,  Yao-Ling Qiu ,  Heejin Kim ,  Yanchun Wang ,  Ly Tam Phan ,  Yat Sun Or

    IPC分类号： A61K31/70 ,  C07H17/08

    CPC分类号： C07D493/08 ,  C07F9/65586 ,  C07H17/08

    摘要： The present invention discloses compounds of formula I, II or X, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.

    摘要翻译： 本发明公开了式I，II或X的化合物或其药学上可接受的盐，酯或前药：其表现出抗菌性质。 本发明还涉及包含上述化合物的药物组合物，用于给予需要抗生素治疗的受试者。 本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的细菌感染的方法。 本发明还包括制备本发明化合物的方法。