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    O-carbamoyl-phenylalaninol compounds, their pharmaceutically useful salts and process for preparing the same
    2.
    发明授权
    O-carbamoyl-phenylalaninol compounds, their pharmaceutically useful salts and process for preparing the same 失效
    O-氨基甲酰基 - 苯丙氨酸醇化合物，其药学上可用的盐及其制备方法

    公开(公告)号：US5756817A

    公开(公告)日：1998-05-26

    申请号：US726675

    申请日：1996-10-07

    申请人： Yong Moon Choi ,  Dong Il Han ,  Yong Kil Kim ,  Hun Woo Shin ,  Jeong-Han Park

    发明人： Yong Moon Choi ,  Dong Il Han ,  Yong Kil Kim ,  Hun Woo Shin ,  Jeong-Han Park

    IPC分类号： C07C271/12 ,  C07C261/00

    CPC分类号： C07C271/12

    摘要： The present invention relates to a racemic or enantiomerically enriched O-carbamoyl-phenylalaninol compound represented by the following structural formula V and pharmaceutically acceptable salts thereof to treat diseases of the central nervous system: ##STR1## wherein Ph is a phenyl group as described as follows: ##STR2## wherein R is a member selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, halogen selected from F, Cl, Br and I, alkoxy containing 1 to 3 carbon atoms, nitro, hydroxy, trifluoromethyl, and thioalkoxy containing 1 to 3 carbon atoms, and x is an integer from 1 to 3, with the proviso that R is the same or different when x is 2 or 3, R.sup.1 and R.sup.2 may be the same or different from each other and are independently selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, aryl, arylalkyl, cyclic propyl and 5 to 7-membered aliphatic cyclic compounds, and R.sup.1 and R.sup.2 may be joined to form a 5 to 7-membered cyclic compound which may comprise zero to one additional nitrogen atom substituted with a member selected from the group consisting of hydrogen, alkyl, and aryl groups, or zero to one oxygen atom directly unconnected, excluding the instance where R, R.sup.1, and R.sup.2 are all hydrogen, and the pharmaceutically acceptable salts thereof. The present invention also relates to O-carbamoyl-(D)-phenylalaninol compounds, represented by the following structural formula IX: ##STR3## wherein Ph, R.sup.1, and R.sup.2 are as described above, and the pharmaceutically acceptable salts thereof.

    摘要翻译： 本发明涉及由以下结构式V表示的外消旋或对映异构体富集的O-氨基甲酰基 - 苯丙氨酸酚化合物及其药学上可接受的盐，用于治疗中枢神经系统疾病：其中Ph是苯基作为 描述如下：其中R是选自氢，1至8个碳原子的低级烷基，选自F，Cl，Br和I的卤素，含1至3个碳原子的烷氧基，硝基， 羟基，三氟甲基和含有1至3个碳原子的硫代烷氧基，x是1至3的整数，条件是当x为2或3时，R相同或不同，R 1和R 2可以相同或不同 彼此独立地选自氢，1至8个碳原子的低级烷基，芳基，芳烷基，环丙基和5至7元脂族环状化合物，并且R 1和R 2可以连接形成5至 7元环状化合物 其可以包括被选自氢，烷基和芳基的成员或直接未连接的0至1个氧原子取代的0至1个另外的氮原子，不包括R 1，R 2和R 2全部为氢的情况， 及其药学上可接受的盐。 本发明还涉及由以下结构式IX表示的O-氨基甲酰基 - （D） - 苯丙氨醇化合物：其中Ph，R 1和R 2如上所述，其药学上可接受的盐。 \！

    O-carbamoyl-(d)-phenylalaninol compounds, their pharmaceutically useful salts and process for preparing the same
    3.
    发明授权
    O-carbamoyl-(d)-phenylalaninol compounds, their pharmaceutically useful salts and process for preparing the same 失效
    O-氨基甲酰基 - （d） - 苯丙氨酸醇化合物，其药学上可用的盐及其制备方法

    公开(公告)号：US5705640A

    公开(公告)日：1998-01-06

    申请号：US596496

    申请日：1996-02-05

    申请人： Yong Moon Choi ,  Dong Il Han ,  Yong Kil Kim

    发明人： Yong Moon Choi ,  Dong Il Han ,  Yong Kil Kim

    IPC分类号： C07C269/04 ,  C07C271/12 ,  C07C271/20 ,  C07D295/205 ,  C07D265/30

    CPC分类号： C07D295/205 ,  C07C271/12 ,  C07B2200/07 ,  C07C2101/02 ,  C07C2101/14

    摘要： The present invention relates to O-carbamoyl-(D)-phenylalaninol compound represented by the following structural formula V and pharmaceutically acceptable salts thereof to treat diseases of the central nervous system: ##STR1## wherein R.sup.1 and R.sup.2 may be the same with or different from each other and are independently selected from the group consisting of hydrogen, lower alkyl containing 1 to 8 carbon atoms, and 5 to 7-membered aliphatic cyclic compounds which may comprise not more than two nitrogen or oxygen atoms directly unconnected, the total number of carbon atom of R.sup.1 and R.sup.2 ranging from 0 to 16.

    摘要翻译： 本发明涉及由以下结构式V表示的O-氨基甲酰基 - （D） - 苯丙氨醛化合物及其药学上可接受的盐以治疗中枢神经系统疾病：其中R1和R2可以相同 独立地选自氢，含有1至8个碳原子的低级烷基和5至7元脂肪族环状化合物，其可以包含不超过两个直接不连接的氮原子或氧原子， R1和R2的碳原子数为0〜16。

    Sulfamate compound containing N-substituted carbamoyl group and method for preparing the same
    4.
    发明授权
    Sulfamate compound containing N-substituted carbamoyl group and method for preparing the same 失效
    含有N-取代氨基甲酰基的氨基磺酸酯化合物及其制备方法

    公开(公告)号：US5892088A

    公开(公告)日：1999-04-06

    申请号：US742929

    申请日：1996-11-01

    申请人： Yong Moon Choi ,  Dong Il Han ,  Hyung Cheol Kim

    发明人： Yong Moon Choi ,  Dong Il Han ,  Hyung Cheol Kim

    IPC分类号： C07C35/20 ,  C07C309/14 ,  C07C309/63 ,  C07C311/05

    CPC分类号： C07C35/20

    摘要： There are disclosed novel sulfamate compounds containing N-substituted carbomoyl group including their racemates and (R)- and (S)-optical isomers represented by Formulas I, II and III, pharmaceutically useful for the prophylaxis and treatment of the disorders of the central nervous system, especially for nervous myalgia, epilepsy and minimal brain dysfunction: ##STR1## (III).

    摘要翻译： 公开了含有N-取代的甲硅烷氧基的新型氨基磺酸酯化合物，包括它们的外消旋物和由式I，II和III表示的（R） - 和（S） - 光学异构体，可用于预防和治疗中枢神经疾病 系统，特别是对于紧张的肌肉酸痛，癫痫和极少的脑功能障碍：（I）（II）（III）（III）。

    Sulfamate compound containing carbamoyl group
    6.
    发明授权
    Sulfamate compound containing carbamoyl group 失效
    氨基甲酸酯化合物

    公开(公告)号：US5654461A

    公开(公告)日：1997-08-05

    申请号：US616077

    申请日：1996-03-14

    申请人： Yong Moon Choi ,  Dong Il Han ,  Hyung Cheol Kim

    发明人： Yong Moon Choi ,  Dong Il Han ,  Hyung Cheol Kim

    IPC分类号： C07C307/02 ,  C07C309/63 ,  A61K31/255 ,  A61K31/27

    CPC分类号： C07C307/02 ,  C07C2101/02

    摘要： 3-O-Carbamoyl-2-phenyl-1,3-propanediol sulfamate racemate, represented by the following structural formula I: ##STR1## and its (R)- and (S)-optical isomers, which are very effective for prophylaxis and the treatment of central nervous system disorders including nervous muscular pain, epilepsy and minimal brain dysfunctions, are disclosed. They are prepared from 2-phenyl-1,3-propanediol monocarbamate and its optical isomers, respectively.

    摘要翻译： 由以下结构式I表示的3-O-氨基甲酰基-2-苯基-1,3-丙二醇氨基磺酸酯外消旋物：其非常有效的（I）及其（R） - 和（S） - 光学异构体 用于预防和治疗包括神经性肌肉疼痛，癫痫和最小脑功能障碍的中枢神经系统疾病。 它们分别由2-苯基-1,3-丙二醇单氨基甲酸酯及其旋光异构体制备。

    Apparatus and method for converting multi-source input images
    7.
    发明授权
    Apparatus and method for converting multi-source input images 失效

    公开(公告)号：US07030932B2

    公开(公告)日：2006-04-18

    申请号：US09908206

    申请日：2001-07-17

    申请人： Dong Il Han

    发明人： Dong Il Han

    IPC分类号： H04N11/20

    CPC分类号： H04N5/44591 ,  G06F3/14 ,  H04N7/01 ,  H04N21/4316 ,  H04N21/4402 ,  H04N21/440218 ,  H04N21/440263 ,  H04N21/440281 ,  H04N21/4622

    摘要： An apparatus and a method for converting multi-source input images are disclosed. The apparatus includes an outside interface part including N outside interface units and pre-processing the input image, a format converting part including N format converters and converting formats and sizes of the pre-processed images as required by a display device, a memory part interacting with each format converter and storing each pre-processed image or format-converted image, a switching part switching the format-converted images according to a display mode, a multiplexer multiplexing the switched images and generating a corresponding display image, and a display processor processing the display image for the display device. Therefore, various input images can be properly converted to have desired formats and sizes based on a display mode of a display device so that the converted multi-images can be adequately displayed on a display device.

    Motion-adaptive interpolation apparatus and method thereof
    8.
    发明授权
    Motion-adaptive interpolation apparatus and method thereof 失效

    公开(公告)号：US06985187B2

    公开(公告)日：2006-01-10

    申请号：US10059173

    申请日：2002-01-31

    申请人： Dong Il Han ,  Chang Yong Shin

    发明人： Dong Il Han ,  Chang Yong Shin

    IPC分类号： H04N7/01

    CPC分类号： H04N7/012 ,  H04N7/0137

    摘要： A motion-adaptive interpolation apparatus and method are disclosed. After an image signal is received and horizontal directional inter-frame motion information of a field to be currently interpolated is estimation, and interpolating is suitably performed based on the motion information. According to one aspect of the present invention, a basic unit image region is set for a pizel to be interpolated, a block matching error (BME) is obtained by moving the basic unit image region at certain intervals in a different direction, a linear interpolated pixel value is detected in consideration of the block matching error, and a final interpolation value is calculated and outputted by applying a rule and filtering based on the linear interpolated pizel value. Thus, a picture quality is improved after de-interlacing, and a circuit for implementation of the operation is simplified, so that a unit cost can be reduced.

    Apparatus for compensating digital video signal
    9.
    发明授权
    Apparatus for compensating digital video signal 失效
    用于补偿数字视频信号的装置

    公开(公告)号：US06724438B2

    公开(公告)日：2004-04-20

    申请号：US09800907

    申请日：2001-03-08

    申请人： In Ho Lee ,  Dong Il Han

    发明人： In Ho Lee ,  Dong Il Han

    IPC分类号： H04N552

    CPC分类号： H04N5/57 ,  G06T5/009 ,  G06T2207/10016 ,  G09G2320/0606 ,  G09G2320/0626

    摘要： An apparatus for displaying a digital video signal includes a shade reflection ratio calculator and a brightness compensator. The shade reflection ratio calculator calculates a shade reflection ratio r of each pixel per display clock using a linear distance function between a center pixel and a current pixel on a screen. The brightness compensator compensates brightness of each pixel by applying the shade reflection ratio value r and a brightness adjustment width Yrate to an input digital video signal. Thus, it is possible to improve picture quality of a video displayed on a screen.

    摘要翻译： 用于显示数字视频信号的装置包括色反射比计算器和亮度补偿器。 阴影反射比率计算器使用屏幕上的中心像素和当前像素之间的线性距离函数来计算每个显示时钟的每个像素的色调反射率r。 亮度补偿器通过将阴影反射比值r和亮度调节宽度Yrate应用于输入数字视频信号来补偿每个像素的亮度。 因此，可以提高在屏幕上显示的视频的图像质量。

    Video format converter
    10.
    发明授权
    Video format converter 有权
    视频格式转换器

    公开(公告)号：US06501509B1

    公开(公告)日：2002-12-31

    申请号：US09487542

    申请日：2000-01-19

    申请人： Dong Il Han

    发明人： Dong Il Han

    IPC分类号： H04N1120

    CPC分类号： H04N7/0135

    摘要： A video format converter for converting resolution of an input digital image to a different resolution includes an adder for adding the number of input pixels L to a feedback value, a modulo operation unit for allowing an output value of the adder as a numerator value to be feedback to the adder if the output value of the adder is smaller than the number of output pixels, but outputting a load signal so that a new data is loaded into them if the output value of the adder is greater than the number of output pixels M, and at the same time for outputting the remainder divided the output value of the adder by the number of output pixels to the adder, and a divider for performing division using the output value of the modulo operation unit as a numerator value and the number of output pixels as a denominator value and for outputting the resultant value as a weighted value &agr;. Since the video format converter has a simple structure, a small amount of hardware can be realized. Also, since there are provided various input/output formats, it is not necessary to correct hardware due to a newly added format. Since differences in color coordinate sampling and scanning types as well as format size are considered, all kinds of format conversion can be realized without addition of a separate hardware.

    摘要翻译： 用于将输入数字图像的分辨率转换为不同分辨率的视频格式转换器包括用于将输入像素数L加到反馈值的加法器，用于允许加法器的输出值作为分子值的模运算单元 如果加法器的输出值小于输出像素的数量，则反馈到加法器，但是如果加法器的输出值大于输出像素M的数量则输出负载信号以便将新的数据加载到加法器 并且同时输出将加法器的输出值除以加法器的输出像素数的余数，以及用于使用模运算单元的输出值作为分子值进行分频的分频器， 输出像素作为分母值，并输出所得到的值作为加权值α。 由于视频格式转换器具有简单的结构，所以可以实现少量的硬件。 此外，由于提供了各种输入/输出格式，所以不需要由于新添加的格式来校正硬件。 由于考虑了颜色坐标采样和扫描类型以及格式大小的差异，所以可以实现各种格式转换，而无需添加单独的硬件。