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1.发明授权Corynebacteria having enhanced L-lysine productivity and a method of producing L-lysine using the same 有权具有增强的L-赖氨酸生产力的棒状杆菌和使用其产生L-赖氨酸的方法公开(公告)号：US09109242B2
公开(公告)日：2015-08-18
申请号：US12441358
申请日：2007-09-17
申请人： Young Hoon Park , Sang Jo Lim , Jun Ok Moon , So Yeon Rah , Hee Jong Lee , Jae Woo Jang , Do Hyun Kwon , Hyo Jin Kim , Jin Suck Sung , Hyung Joon Kim
发明人： Young Hoon Park , Sang Jo Lim , Jun Ok Moon , So Yeon Rah , Hee Jong Lee , Jae Woo Jang , Do Hyun Kwon , Hyo Jin Kim , Jin Suck Sung , Hyung Joon Kim
CPC分类号： C12P13/08 , C12N9/001 , C12N9/1096 , C12N9/1217 , C12N9/88
摘要： A variant of Corynebacterium shows activity greater than the endogenous activity of aspartate aminotransferase, aspartate kinase, aspartate semialdehyde dehydrogenase, dihydrodipicolinate synthase, dihydropicolinate reductase and diaminopimelate dicarboxylase and additionally pyruvate carboxylase. The variant is used in a method of producing L-lysine.
摘要翻译： 棒状杆菌的变体显示出比天冬氨酸氨基转移酶，天冬氨酸激酶，天冬氨酸半醛脱氢酶，二氢吡啶二羧酸合酶，二氢吡啶甲酸酯还原酶和二氨基庚二酸二羧酸酶以及另外的丙酮酸羧化酶的内源性活性更大的活性。 该变体用于生产L-赖氨酸的方法。
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2.发明申请CORYNEBACTERIA HAVING ENHANCED L-LYSINE PRODUCTIVITY AND A METHOD OF PRODUCING L-LYSINE USING THE SAME 有权具有增强的L-赖氨酸生产力的罗非鱼和使用该L-赖氨酸生产L-赖氨酸的方法公开(公告)号：US20100143984A1
公开(公告)日：2010-06-10
申请号：US12441358
申请日：2007-09-17
申请人： Young Hoon Park , Sang Jo Lim , Jun Ok Moon , So Yeon Rah , Hee Jong Lee , Jae Woo Jang , Do Hyun Kwon , Hyo Jin Kim , Jin Suck Sung , Hyung Joon Kim
发明人： Young Hoon Park , Sang Jo Lim , Jun Ok Moon , So Yeon Rah , Hee Jong Lee , Jae Woo Jang , Do Hyun Kwon , Hyo Jin Kim , Jin Suck Sung , Hyung Joon Kim
CPC分类号： C12P13/08 , C12N9/001 , C12N9/1096 , C12N9/1217 , C12N9/88
摘要： A variant of Corynebacterium shows activity greater than the endogenous activity of aspartate aminotransferase, aspartate kinase, aspartate semialdehyde dehydrogenase, dihydrodipicolinate synthase, dihydropicolinate reductase and diaminopimelate dicarboxylase and additionally pyruvate carboxylase. The variant is used in a method of producing L-lysine.
摘要翻译： 棒状杆菌的变体显示出比天冬氨酸氨基转移酶，天冬氨酸激酶，天冬氨酸半醛脱氢酶，二氢吡啶二羧酸合酶，二氢吡啶甲酸酯还原酶和二氨基庚二酸二羧酸酶以及另外的丙酮酸羧化酶的内源性活性更大的活性。 该变体用于生产L-赖氨酸的方法。
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3.发明申请CORYNEBACTERIUM SP. TRANSFORMED WITH A FRUCTOKINASE GENE DERIVED FROM ESCHERICHIA SP. AND PROCESS FOR PREPARING L-AMINO ACID USING THE SAME 有权红霉素 用来自ESCHERICHIA SP的FRUCTOKINASE基因转化。 和使用该方法制备L-氨基酸的方法和方法公开(公告)号：US20140099680A1
公开(公告)日：2014-04-10
申请号：US14007941
申请日：2012-04-02
申请人： Hyun Won Bae , Hyung Joon Kim , Jun Ok Moon , Jae Woo Jang , Jong Chul Kim , Tae Han Kim , Jin Suck Sung , Kyung Han Lee , Dae Cheol Kim , Hyo Jin Kim , Hyun Ae Bae , Sang Jo Lim
发明人： Hyun Won Bae , Hyung Joon Kim , Jun Ok Moon , Jae Woo Jang , Jong Chul Kim , Tae Han Kim , Jin Suck Sung , Kyung Han Lee , Dae Cheol Kim , Hyo Jin Kim , Hyun Ae Bae , Sang Jo Lim
CPC分类号： C12P13/14 , C12N9/1205 , C12P13/04 , C12P13/08 , C12Y207/01004
摘要： The present invention relates to Corynebacterium sp. that is transformed with an Escherichia sp.-derived fructokinase gene to express fructokinase showing a sufficient activity of converting fructose into fructose-6-phosphate, thereby preventing unnecessary energy consumption, and a method for producing L-amino acids using the strain. The transformed Corynebacterium sp. of the present invention is able to express fructokinase from the Escherichia-derived fructokinase gene to prevent unnecessary energy consumption during fructose metabolism, leading to more cost-effective production of L-amino acids. Therefore, it can be widely used for the effective production of L-amino acids.
摘要翻译： 本发明涉及棒状杆菌属 用Escherichia sp.衍生的果糖激酶基因转化以表达果糖激酶，其显示出将果糖转化为果糖-6-磷酸的足够活性，从而防止不必要的能量消耗，以及使用该菌株产生L-氨基酸的方法。 转化的棒状杆菌属 本发明能够从来自大肠杆菌的果糖激酶基因中表达果糖激酶，以防止在果糖代谢期间不必要的能量消耗，导致L-氨基酸的更具成本效益的生产。 因此，可广泛用于L-氨基酸的有效生产。
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4.发明授权Corynebacterium sp. transformed with a fructokinase gene derived from Escherichia sp. and process for preparing L-amino acid using the same 有权棒状杆菌 用来自大肠杆菌的果糖激酶基因转化。 以及使用其制备L-氨基酸的方法公开(公告)号：US09267161B2
公开(公告)日：2016-02-23
申请号：US14007941
申请日：2012-04-02
申请人： Hyun Won Bae , Hyung Joon Kim , Jun Ok Moon , Jae Woo Jang , Jong Chul Kim , Tae Han Kim , Jin Suck Sung , Kyung Han Lee , Dae Cheol Kim , Hyo Jin Kim , Hyun Ae Bae , Sang Jo Lim
发明人： Hyun Won Bae , Hyung Joon Kim , Jun Ok Moon , Jae Woo Jang , Jong Chul Kim , Tae Han Kim , Jin Suck Sung , Kyung Han Lee , Dae Cheol Kim , Hyo Jin Kim , Hyun Ae Bae , Sang Jo Lim
CPC分类号： C12P13/14 , C12N9/1205 , C12P13/04 , C12P13/08 , C12Y207/01004
摘要： The present invention relates to Corynebacterium sp. that is transformed with an Escherichia sp.-derived fructokinase gene to express fructokinase showing a sufficient activity of converting fructose into fructose-6-phosphate, thereby preventing unnecessary energy consumption, and a method for producing L-amino acids using the strain. The transformed Corynebacterium sp. of the present invention is able to express fructokinase from the Escherichia-derived fructokinase gene to prevent unnecessary energy consumption during fructose metabolism, leading to more cost-effective production of L-amino acids. Therefore, it can be widely used for the effective production of L-amino acids.
摘要翻译： 本发明涉及棒状杆菌属 用Escherichia sp.衍生的果糖激酶基因转化以表达果糖激酶，其显示出将果糖转化为果糖-6-磷酸的足够活性，从而防止不必要的能量消耗，以及使用该菌株产生L-氨基酸的方法。 转化的棒状杆菌属 本发明能够从来自大肠杆菌的果糖激酶基因中表达果糖激酶，以防止在果糖代谢期间不必要的能量消耗，导致L-氨基酸的更具成本效益的生产。 因此，可广泛用于L-氨基酸的有效生产。
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公开(公告)号：US08329434B2
公开(公告)日：2012-12-11
申请号：US13037790
申请日：2011-03-01
申请人： Do Hyun Kwon , Hyung Joon Kim , Jae Woo Jang , Jun Ok Moon , Sang Jo Lim
发明人： Do Hyun Kwon , Hyung Joon Kim , Jae Woo Jang , Jun Ok Moon , Sang Jo Lim
CPC分类号： C12N15/77 , C12N9/1096 , C12P13/08
摘要： The present invention provides a nucleic acid molecule having enhanced promoter activity, which is operably linked to a gene encoding aspartate aminotransferase and derived from Corynebacterium glutamicum, a vector comprising the nucleic acid molecule, a transformant transformed with the vector, and a method for producing L-lysine using the transformant.
摘要翻译： 本发明提供了具有增强的启动子活性的核酸分子，其与编码天冬氨酸氨基转移酶并衍生自谷氨酸棒杆菌的基因可操作地连接，包含核酸分子的载体，用该载体转化的转化体，以及用于产生L - 赖氨酸使用转化体。
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公开(公告)号：US20110217741A1
公开(公告)日：2011-09-08
申请号：US13037790
申请日：2011-03-01
申请人： Do Hyun Kwon , Hyung Joon Kim , Jae Woo Jang , Jun Ok Moon , Sang Jo Lim
发明人： Do Hyun Kwon , Hyung Joon Kim , Jae Woo Jang , Jun Ok Moon , Sang Jo Lim
CPC分类号： C12N15/77 , C12N9/1096 , C12P13/08
摘要： The present invention provides a nucleic acid molecule having enhanced promoter activity, which is operably linked to a gene encoding aspartate aminotransferase and derived from Corynebacterium glutamicum, a vector comprising the nucleic acid molecule, a transformant transformed with the vector, and a method for producing L-lysine using the transformant.
摘要翻译： 本发明提供了具有增强的启动子活性的核酸分子，其与编码天冬氨酸氨基转移酶并衍生自谷氨酸棒杆菌的基因可操作地连接，包含核酸分子的载体，用该载体转化的转化体，以及用于产生L - 赖氨酸使用转化体。
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7.发明申请Microorganism with Enhanced L-Lysine Productivity and Method for Producing L-Lysine Using the Same 审中-公开具有增强的L-赖氨酸生产力的微生物和使用其生产L-赖氨酸的方法公开(公告)号：US20130102037A1
公开(公告)日：2013-04-25
申请号：US13378145
申请日：2011-07-15
申请人： Sang Jo Lim , Jun Ok Moon , Hyung Joon Kim , Jae Woo Jang , Jae Yong Cho
发明人： Sang Jo Lim , Jun Ok Moon , Hyung Joon Kim , Jae Woo Jang , Jae Yong Cho
IPC分类号： C12N15/77
CPC分类号： C12N15/77 , C12N9/1205 , C12P13/08
摘要： Disclosed is an L-lysine-producing microorganism having gluconate kinase activity weakened in comparison to the endogenous activity thereof, and methods provided for preparing the microorganism and for producing L-lysine using the same.
摘要翻译： 公开了与其内源活性相比，具有葡萄糖酸激酶活性弱的L-赖氨酸生产微生物，以及提供用于制备微生物和使用该微生物生产L-赖氨酸的方法。
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公开(公告)号：US10939983B2
公开(公告)日：2021-03-09
申请号：US15536135
申请日：2014-12-16
申请人： Jae Woo Jang
发明人： Jae Woo Jang
IPC分类号： A61C8/00
摘要： The present invention relates to an implant unit, particularly, a dental implant unit for mitigating impact which may be substituted for a natural tooth, the dental implant unit including: a crown; an abutment which has one side coupled to the crown; and a fixture which is coupled to the other side of the abutment, in which at least one of the abutment and the fixture has an elastic layer, and also relates to a dental implant unit including: a crown; an abutment which has one side coupled to the crown; and a fixture which is coupled to the other side of the abutment, in which at least one of the abutment and the fixture has an elastic layer that is formed at a portion which is in contact with a gingiva when an implant operation is performed using the dental implant unit.
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公开(公告)号：US10034962B2
公开(公告)日：2018-07-31
申请号：US15633769
申请日：2017-06-27
申请人： Jae Woo Jang
发明人： Jae Woo Jang
CPC分类号： A61L27/34 , A61C8/0006 , A61C8/0092 , A61F2/2803 , A61F2002/2839 , A61F2310/00359 , A61L27/3608 , A61L27/365 , A61L27/3691 , A61L2430/02 , A61L2430/12 , C08L89/06
摘要： An implant for bone-graft insertedly placed in a procedure pore, the implant includes a bone organism having a lump shape, and a protective film coated to cover an overall outer surface of the bone organism as to form an absorbent membrane. After the implant is insertedly placed in the procedure pore, the absorbent member is absorbed into a body and dissolved as time passes. The implant for the bone-graft may be applied to diverse procedures performed for hone-graft not only in a dental surgery but also in orthopedics or a plastic surgery.
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公开(公告)号：US11083540B2
公开(公告)日：2021-08-10
申请号：US15536136
申请日：2014-12-16
申请人： Jae Woo Jang
发明人： Jae Woo Jang
摘要： The present invention relates to an implant unit, particularly, a dental implant unit for mitigating impact which may be substituted for a natural tooth, the dental implant unit including: a crown; an abutment which has one side coupled to the crown; and a fixture which is coupled to the other side of the abutment, in which at least one of the abutment and the fixture has an elastic layer that is cut out in one direction, and also relates to a dental implant unit including: a crown; an implant structural body which has one side coupled to the crown, and the other side implanted from a gingiva to an alveolar bone, in which the implant structural body has an elastic layer that is cut out to have multiple layers.
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