公开(公告)号：US20140179691A1

公开(公告)日：2014-06-26

申请号：US14008702

申请日：2012-03-29

申请人： Young Lag Cho ,  Sung Yoon Baek ,  Sang Eun Chae ,  Sun Young Kim ,  Hong Bum Lee ,  Hyang Sook Lee ,  Kyuman Oh ,  Tae Kyo Park ,  Sung Ho Woo ,  Yong Zu Kim ,  Hye Jin Heo

发明人： Young Lag Cho ,  Sung Yoon Baek ,  Sang Eun Chae ,  Sun Young Kim ,  Hong Bum Lee ,  Hyang Sook Lee ,  Kyuman Oh ,  Tae Kyo Park ,  Sung Ho Woo ,  Yong Zu Kim ,  Hye Jin Heo

IPC分类号： C07D413/14

CPC分类号： C07D413/14

摘要： Disclosed is a novel oxazolidinone derivative represented by Formula 1 above, in particular, a novel oxazolidinone compound having a cyclic amidoxime or cyclic amidrazone group.In Formula 1, R and Q are the same as defined in the detailed description.In addition, disclosed is a pharmaceutical composition for an antibiotic which includes the novel oxazolidinone derivative of Formula 1, a prodrug thereof, a hydrate thereof, a solvate thereof, an isomer thereof, or a pharmaceutically acceptable salt thereof as an active ingredient.The novel oxazolidinone derivative, the prodrug thereof, the hydrate thereof, the solvate thereof, the isomer thereof, and the pharmaceutically acceptable salt thereof have broad antibacterial spectrum against resistant bacteria, low toxicity and strong antibacterial effects against Gram-positive and Gram-negative bacteria and thus may be effectively used as antibiotics.

摘要翻译： 公开了上述通式1所示的新型恶唑烷酮衍生物，特别是具有环状偕胺肟或环状氨基腙基的新型恶唑烷酮化合物。 在式1中，R和Q与详细描述中定义相同。 此外，公开了一种抗生素的药物组合物，其包含式1的新型恶唑烷酮衍生物，其前药，其水合物，其溶剂合物，其异构体或其药学上可接受的盐作为活性成分。 新型恶唑烷酮衍生物，其前体药剂，其水合物，其溶剂合物，其异构体及其药学上可接受的盐具有抗抗性细菌的抗菌谱，对革兰氏阳性和革兰氏阴性菌具有低毒性和强抗菌作用 因此可以有效地用作抗生素。

公开(公告)号：US08846669B2

公开(公告)日：2014-09-30

申请号：US14008702

申请日：2012-03-29

申请人： Young Lag Cho ,  Sung Yoon Baek ,  Sang Eun Chae ,  Sun Young Kim ,  Hong Bum Lee ,  Hyang Sook Lee ,  Kyuman Oh ,  Hye Jin Heo ,  Tae Kyo Park ,  Sung Ho Woo ,  Yong Zu Kim

发明人： Young Lag Cho ,  Sung Yoon Baek ,  Sang Eun Chae ,  Sun Young Kim ,  Hong Bum Lee ,  Hyang Sook Lee ,  Kyuman Oh ,  Hye Jin Heo ,  Tae Kyo Park ,  Sung Ho Woo ,  Yong Zu Kim

IPC分类号： C07D413/14 ,  A61K31/53 ,  A61K31/5355

CPC分类号： C07D413/14

摘要： Disclosed is a novel oxazolidinone derivative represented by Formula 1 above, in particular, a novel oxazolidinone compound having a cyclic amidoxime or cyclic amidrazone group.In Formula 1, R and Q are the same as defined in the detailed description.In addition, disclosed is a pharmaceutical composition for an antibiotic which includes the novel oxazolidinone derivative of Formula 1, a prodrug thereof, a hydrate thereof, a solvate thereof, an isomer thereof, or a pharmaceutically acceptable salt thereof as an active ingredient.The novel oxazolidinone derivative, the prodrug thereof, the hydrate thereof, the solvate thereof, the isomer thereof, and the pharmaceutically acceptable salt thereof have broad antibacterial spectrum against resistant bacteria, low toxicity and strong antibacterial effects against Gram-positive and Gram-negative bacteria and thus may be effectively used as antibiotics.

摘要翻译： 公开了上述通式1所示的新型恶唑烷酮衍生物，特别是具有环状偕胺肟或环状氨基腙基的新型恶唑烷酮化合物。 在式1中，R和Q与详细描述中定义相同。 此外，公开了一种抗生素的药物组合物，其包含式1的新型恶唑烷酮衍生物，其前药，其水合物，其溶剂合物，其异构体或其药学上可接受的盐作为活性成分。 新型恶唑烷酮衍生物，其前体药剂，其水合物，其溶剂合物，其异构体及其药学上可接受的盐具有抗抗性细菌的抗菌谱，对革兰氏阳性和革兰氏阴性菌具有低毒性和强抗菌作用 因此可以有效地用作抗生素。

公开(公告)号：US20160213786A1

公开(公告)日：2016-07-28

申请号：US15054257

申请日：2016-02-26

申请人： Yong Zu Kim ,  Tae Kyo Park ,  Sung Ho Woo ,  Hyang Sook Lee ,  Sun Young Kim ,  Jong Un Cho ,  Doo Hwan Jung ,  Youngun Kim ,  Hyun Jin Kwon ,  Kyu Man Oh ,  Yunseo Chung ,  Yun Hee Park

发明人： Yong Zu Kim ,  Tae Kyo Park ,  Sung Ho Woo ,  Hyang Sook Lee ,  Sun Young Kim ,  Jong Un Cho ,  Doo Hwan Jung ,  Youngun Kim ,  Hyun Jin Kwon ,  Kyu Man Oh ,  Yunseo Chung ,  Yun Hee Park

IPC分类号： A61K47/48

CPC分类号： A61K47/6811 ,  A61K47/549 ,  A61K47/55 ,  A61K47/65 ,  A61K47/6803 ,  A61K47/6817 ,  A61K47/6849 ,  A61K47/6851 ,  A61K47/6855 ,  A61K47/6859 ,  A61K47/6889 ,  C07K16/2863 ,  C07K16/32 ,  C12Q1/48

摘要： The invention provides methods for preparing an antibody-active agent conjugate. The conjugate comprises an antibody, a cysteine residue of an amino acid motif that can be recognized by an isoprenoid transferase located at or after the carboxy-terminus of the antibody, an isoprenoid unit operably linked to the cysteine residue, and an active agen. The invention also provides a composition comprising the antibody-active agent conjugate prepared by the methods.

摘要翻译： 本发明提供了制备抗体 - 活性剂缀合物的方法。 缀合物包含抗体，氨基酸基序的半胱氨酸残基，其可被位于抗体的羧基末端或之后的类异戊二烯转移酶识别，与半胱氨酸残基可操作地连接的类异戊二烯单元和活性成分。 本发明还提供包含通过该方法制备的抗体 - 活性剂缀合物的组合物。

公开(公告)号：US09449986B1

公开(公告)日：2016-09-20

申请号：US14975876

申请日：2015-12-21

申请人： Hyun Sook Yoon ,  Jang Gn Yun ,  Sun Young Kim ,  Jae Ho Jeong

发明人： Hyun Sook Yoon ,  Jang Gn Yun ,  Sun Young Kim ,  Jae Ho Jeong

IPC分类号： H01L27/115 ,  H01L29/788 ,  H01L29/792 ,  H01L29/423 ,  H01L23/528

CPC分类号： H01L27/11582 ,  H01L27/11519 ,  H01L27/11526 ,  H01L27/11548 ,  H01L27/11556 ,  H01L27/11565 ,  H01L27/11573 ,  H01L27/11575 ,  H01L27/1158

摘要： A memory device includes a cell region including a channel region extending to be perpendicular to an upper surface of a substrate, a plurality of gate electrode layers stacked on the substrate adjacently to the channel region, a peripheral circuit region including a first active region disposed in the vicinity of the cell region, a second active region having an area larger than an area of the first active region, a plurality of first contacts connected to the first active region, and a plurality of second contacts connected to the second active region. A distance between the plurality of first contacts is less than that between the plurality of second contacts.

摘要翻译： 存储器件包括：单元区域，其包括垂直于衬底的上表面延伸的沟道区;与衬底相邻的多个栅电极层，与沟道区相邻;外围电路区，包括设置在第一有源区中的第一有源区; 单元区域附近，具有比第一有源区域的面积大的面积的第二有源区域，连接到第一有源区域的多个第一触点和连接到第二有源区域的多个第二触点。 多个第一触点之间的距离小于多个第二触点之间的距离。

公开(公告)号：US08637122B2

公开(公告)日：2014-01-28

申请号：US11950336

申请日：2007-12-04

申请人： Geon-Woong Lee ,  Joong Tak Han ,  Jong Seok Woo ,  Sun Young Kim

发明人： Geon-Woong Lee ,  Joong Tak Han ,  Jong Seok Woo ,  Sun Young Kim

IPC分类号： B05D5/12 ,  B05D1/12 ,  B05D3/02 ,  B05D3/00 ,  B29C71/02

CPC分类号： H01B1/24 ,  C08K3/041 ,  C09D163/00 ,  C09D163/10 ,  Y10T428/25

摘要： This invention relates to a method of manufacturing a transparent conductive film containing carbon nanotubes and a binder, in which the carbon nanotubes are subjected to acid treatment, dispersion in a solvent, mixing with the binder, and application on the substrate, and to a transparent conductive film manufactured thereby. The method includes subjecting carbon nanotubes having an outer diameter of less than 15 nm to acid treatment to thus purify and surface functionalize them, followed by dispersing the treated carbon nanotubes in a solvent along with the binder, or mixing a carbon nanotube solution using a polar or nonpolar solvent with a binder solution, and applying the mixture on the substrate. Through the application of the mixture of treated carbon nanotubes and binder on the substrate, the transparent conductive film has improved transparency, electrical conductivity, dispersibility, substrate adhesiveness, chemical stability, durability and scratch resistance, and can be applied to various substrates, including hard or flexible substrates, thanks to high substrate adhesiveness and applicability. A solution in which the surface functionalized carbon nanotubes are well dispersed is prepared, thus facilitating the manufacture of the film using various materials and generating economic benefits.

摘要翻译： 本发明涉及一种制造含有碳纳米管和粘合剂的透明导电膜的方法，其中碳纳米管经受酸处理，在溶剂中分散，与粘合剂混合，并施加在基材上， 由此制造导电膜。 该方法包括使外径小于15nm的碳纳米管进行酸处理，从而净化和表面官能化，然后将处理过的碳纳米管与粘合剂一起分散在溶剂中，或者使用极性混合碳纳米管溶液 或非极性溶剂与粘合剂溶液混合，并将该混合物施加在基材上。 通过将处理后的碳纳米管和粘合剂的混合物应用于基板，透明导电膜的透明性，导电性，分散性，基板粘合性，化学稳定性，耐久性和耐划伤性提高，可以应用于各种基材，包括硬 或柔性基板，由于高的基材粘合性和适用性。 制备表面官能化碳纳米管良好分散的溶液，从而便于使用各种材料制造薄膜并产生经济效益。

公开(公告)号：US20130206977A1

公开(公告)日：2013-08-15

申请号：US13816560

申请日：2011-08-12

申请人： Byong Chul Yoo ,  In Hoo Kim ,  Kyung Hee Kim ,  Jun Hwa Lee ,  Kwang Gi Kim ,  Hee Jin Chang ,  Dae Yong Kim ,  Jae Hwan Oh ,  Byung Chang Kim ,  Ji Won PARK ,  Sun Young Kim

发明人： Byong Chul Yoo ,  In Hoo Kim ,  Kyung Hee Kim ,  Jun Hwa Lee ,  Kwang Gi Kim ,  Hee Jin Chang ,  Dae Yong Kim ,  Jae Hwan Oh ,  Byung Chang Kim ,  Ji Won PARK ,  Sun Young Kim

IPC分类号： H01J49/00

CPC分类号： H01J49/0036 ,  G01N33/57419 ,  G01N33/6848 ,  G06F19/24 ,  G06F19/703

摘要： The present invention provides a method for crystallizing low mass ions for diagnosing colorectal cancer by using a MALDI-TOF mass spectrometer to biostatistically analyze low mass ions, which are extracted from a biological sample, and a method for providing information for diagnosing colorectal cancer using same. The present inventions can provide a diagnostic method, which requires low cost and a short time for analysis, can analyze large areas, and which can provide superior and credible discriminations.

摘要翻译： 本发明提供了一种通过使用MALDI-TOF质谱仪来生物统计分析从生物样品提取的低质量离子来结晶用于诊断结肠直肠癌的低质量离子的方法，以及提供用于使用其诊断结肠直肠癌的信息的方法 。 本发明可以提供诊断方法，其需要低成本和短时间的分析，可以分析大面积，并且可以提供优异和可信的辨别。

公开(公告)号：US20110007090A1

公开(公告)日：2011-01-13

申请号：US12853904

申请日：2010-08-10

申请人： In Jae Chung ,  Jong Hee Hwang ,  Sun Young Kim

发明人： In Jae Chung ,  Jong Hee Hwang ,  Sun Young Kim

IPC分类号： G09G5/02 ,  G06F12/00

CPC分类号： G09G3/3648 ,  G09G3/2025 ,  G09G3/2051 ,  G09G3/2055 ,  G09G2320/0285 ,  G09G2330/10

摘要： A flat panel display device and a picture quality controlling method thereof is provided. The flat panel display device includes a display panel. A memory stores location information about a panel defect location on the display panel and a compensation value to be dispersed for a plurality of frame periods. A compensating part detects the data to be displayed at the panel defect location and adjusts the data to be displayed at the panel defect location with the compensation value from the memory.

摘要翻译： 提供了一种平板显示装置及其图像质量控制方法。 平板显示装置包括显示面板。 存储器存储关于显示面板上的面板缺陷位置的位置信息以及要在多个帧周期中分散的补偿值。 补偿部分检测要在面板缺陷位置显示的数据，并用来自存储器的补偿值调整要在面板缺陷位置显示的数据。

公开(公告)号：US07724230B2

公开(公告)日：2010-05-25

申请号：US11375035

申请日：2006-03-15

申请人： Sun Young Kim ,  Chul Sang Jang ,  Jong Hoon Kim

发明人： Sun Young Kim ,  Chul Sang Jang ,  Jong Hoon Kim

IPC分类号： G09G3/36

CPC分类号： G09G3/2003 ,  G09G3/3648 ,  G09G2300/0426 ,  G09G2310/0218

摘要： A driving circuit of a display device includes a timing controller for combining p first digital data signals (p being a positive integer greater than 1) corresponding to colors for displaying images to generate q second digital data signals and for supplying the q second digital data signals to first to qth data transmission lines (q being a positive integer smaller than p), and a plurality of data driver integrated circuits for processing the q second digital data signals from the timing controller to restore the p first digital data signals, converting the p restored digital data signals into analog data signals, and supplying the analog data signals to a display panel.

摘要翻译： 显示装置的驱动电路包括：时序控制器，用于组合对应于用于显示图像的颜色的p个第一数字数据信号（p是大于1的正整数）以产生q个第二数字数据信号，并用于提供q个第二数字数据信号 到第一至第q数据传输线（q是小于p的正整数）和多个数据驱动器集成电路，用于处理来自定时控制器的q个第二数字数据信号以恢复p个第一数字数据信号，转换p 将数字数据信号恢复为模拟数据信号，并将模拟数据信号提供给显示面板。

公开(公告)号：US20100048570A1

公开(公告)日：2010-02-25

申请号：US12523285

申请日：2008-01-16

申请人： Sung Soo Kim ,  Jin Hee Ahn ,  Hyae Gyeong Cheon ,  Sang Dal Rhee ,  Nam Sook Kang ,  Ki Young Kim ,  Seung Kyu Kang ,  Won Hoon Jung ,  Sung Gyu Kim ,  Sun Young Kim ,  Jae Hong Kweon ,  Sang Kwon Sohn ,  Min Ki Shin ,  Ni Na Ha

发明人： Sung Soo Kim ,  Jin Hee Ahn ,  Hyae Gyeong Cheon ,  Sang Dal Rhee ,  Nam Sook Kang ,  Ki Young Kim ,  Seung Kyu Kang ,  Won Hoon Jung ,  Sung Gyu Kim ,  Sun Young Kim ,  Jae Hong Kweon ,  Sang Kwon Sohn ,  Min Ki Shin ,  Ni Na Ha

IPC分类号： A61K31/5377 ,  C07D277/00 ,  C07D415/00 ,  A61K31/426

CPC分类号： C07D277/06 ,  C07D417/12 ,  Y02P20/55

摘要： The present invention relates to novel 2-carbonyl-3-acyl-1,3-thiazolidines having a β-amino group on the acyl chain, in free, prodrug form or pharmaceutically acceptable salt thereof, including their enantiomers, diastereomers and racemates, as efficient inhibitors against DPP-IV. The invention further relates to the pharmaceutical compositions comprising the disclosed compounds. The present invention also relates to methods for preparing the disclosed compounds and for treating DPP-IV-mediated diseases.

摘要翻译： 本发明涉及在酰基链上具有游离的前药形式或其药学上可接受的盐，包括它们的对映异构体，非对映异构体和外消旋体的具有“ - ” - 氨基的新的2-羰基-3-酰基-1,3-噻唑烷， 作为DPP-IV的有效抑制剂。 本发明还涉及包含所公开的化合物的药物组合物。 本发明还涉及制备所公开的化合物和用于治疗DPP-IV介导的疾病的方法。

公开(公告)号：US20080062113A1

公开(公告)日：2008-03-13

申请号：US11889045

申请日：2007-08-08

申请人： Sun Young Kim

发明人： Sun Young Kim

IPC分类号： G09G3/36 ,  G11C19/00

CPC分类号： G11C19/00 ,  G09G3/3688 ,  G09G2310/027 ,  G11C19/28

摘要： Disclosed are a shift register capable of reducing power consumption, a data driver having the same, and a liquid crystal display device. The shift register includes a storing cell array including storage cells which store a plurality of serial data, and a control array for outputting sampling signals, which are sequentially shifted every period of data transmission such that the storage cells sequentially store the data, in response to at least one clock signal having a frequency lower than a transmission frequency of the data.

摘要翻译： 公开了能够降低功耗的移位寄存器，具有该移位寄存器的数据驱动器和液晶显示装置。 移位寄存器包括存储单元阵列，该存储单元阵列包括存储多个串行数据的存储单元，以及用于输出采样信号的控制阵列，每个周期的数据传输顺序地移位，使得存储单元顺序存储数据，响应于 至少一个时钟信号的频率低于数据的传输频率。