公开(公告)号：US08740994B2

公开(公告)日：2014-06-03

申请号：US14116757

申请日：2012-05-10

申请人： Yoshihiko Hirose ,  Yukihide Sato

发明人： Yoshihiko Hirose ,  Yukihide Sato

IPC分类号： A61Q5/10 ,  A61K8/66

CPC分类号： A61K8/99 ,  A61K8/66 ,  A61Q5/10 ,  C12N9/001 ,  C12N9/0057 ,  C12N9/0059 ,  C12N9/0061 ,  C12N9/0063 ,  C12N9/0071 ,  C12P13/00 ,  C12Y103/03005 ,  C12Y110/03001 ,  C12Y110/03002 ,  C12Y110/03003 ,  C12Y110/03004 ,  C12Y114/18001 ,  D06P1/32 ,  D06P3/14

摘要： The object is to provide a process for dyeing that can provide an excellent dyeing effect while utilizing an oxidase, and a dyeing agent for use in the process. Provided is a dyeing agent comprising a modified enzyme obtained by adding positive charge by a chemical modification with an amine to an enzyme selected from the group consisting of an enzyme specified as EC 1.10.3.1, an enzyme specified as EC 1.10.3.2, an enzyme specified as EC 1.3.3.5, an enzyme specified as EC 1.10.3.4, an enzyme specified as EC 1.10.3.3 and an enzyme specified as EC 1.14.18.1. A process for dyeing using the dyeing agent is also provided.

摘要翻译： 本发明的目的是提供一种可以在使用氧化酶时提供优异的染色效果的染色方法和用于该方法的染色剂。 提供了一种染色剂，其包含通过化学修饰将正电荷与胺相加的酶所选择的酶所选择的酶，所述酶选自指定为EC1.10.3.1的酶，规定为EC1.10.3.2的酶，酶 规定为EC 1.3.3.5，规定为EC 1.10.3.4的酶，指定为EC 1.10.3.3的酶和指定为EC 1.14.18.1的酶。 还提供了使用染色剂进行染色的方法。

公开(公告)号：US20140068875A1

公开(公告)日：2014-03-13

申请号：US14116757

申请日：2012-05-10

申请人： Yoshihiko Hirose ,  Yukihide Sato

发明人： Yoshihiko Hirose ,  Yukihide Sato

IPC分类号： A61K8/99 ,  A61Q5/10

CPC分类号： A61K8/99 ,  A61K8/66 ,  A61Q5/10 ,  C12N9/001 ,  C12N9/0057 ,  C12N9/0059 ,  C12N9/0061 ,  C12N9/0063 ,  C12N9/0071 ,  C12P13/00 ,  C12Y103/03005 ,  C12Y110/03001 ,  C12Y110/03002 ,  C12Y110/03003 ,  C12Y110/03004 ,  C12Y114/18001 ,  D06P1/32 ,  D06P3/14

摘要： The object is to provide a process for dyeing that can provide an excellent dyeing effect while utilizing an oxidase, and a dyeing agent for use in the process. Provided is a dyeing agent comprising a modified enzyme obtained by adding positive charge by a chemical modification with an amine to an enzyme selected from the group consisting of an enzyme specified as EC 1.10.3.1, an enzyme specified as EC 1.10.3.2, an enzyme specified as EC 1.3.3.5, an enzyme specified as EC 1.10.3.4, an enzyme specified as EC 1.10.3.3 and an enzyme specified as EC 1.14.18.1. A process for dyeing using the dyeing agent is also provided.

摘要翻译： 本发明的目的是提供一种可以在使用氧化酶时提供优异的染色效果的染色方法和用于该方法的染色剂。 提供了一种染色剂，其包含通过化学修饰将正电荷与胺相加的酶所选择的酶所选择的酶，所述酶选自指定为EC1.10.3.1的酶，规定为EC1.10.3.2的酶，酶 规定为EC 1.3.3.5，规定为EC 1.10.3.4的酶，指定为EC 1.10.3.3的酶和指定为EC 1.14.18.1的酶。 还提供了使用染色剂进行染色的方法。

公开(公告)号：US09358198B2

公开(公告)日：2016-06-07

申请号：US14369500

申请日：2012-01-04

申请人： Yukihide Sato ,  Yoshihiko Hirose

发明人： Yukihide Sato ,  Yoshihiko Hirose

IPC分类号： A61K8/49 ,  A61K8/66 ,  A61Q5/10 ,  C12N9/02 ,  A61K8/99

CPC分类号： A61K8/4913 ,  A61K8/492 ,  A61K8/66 ,  A61K8/99 ,  A61K2800/10 ,  A61Q5/10 ,  C12N9/001 ,  C12Y103/03005

摘要： The problem is to provide a means for effectively dyeing keratin fibers while retaining high safety. Provided are a dyeing method and a dyeing agent, which include a combination of an oxidation dyeing agent consisting of an indole analog and a bilirubin oxidase derived from Myrothecium verrucaria or Bacillus Subtilis.

摘要翻译： 问题在于提供有效染色角蛋白纤维同时保持高安全性的手段。 提供了一种染色方法和染色剂，其包括由吲哚类似物组成的氧化染色剂和源自疣状黑曲霉或枯草芽孢杆菌的胆红素氧化酶的组合。

公开(公告)号：US20140359950A1

公开(公告)日：2014-12-11

申请号：US14369500

申请日：2012-01-04

申请人： Yukihide Sato ,  Yoshihiko Hirose

发明人： Yukihide Sato ,  Yoshihiko Hirose

IPC分类号： A61K8/49 ,  A61K8/99 ,  A61Q5/10

CPC分类号： A61K8/4913 ,  A61K8/492 ,  A61K8/66 ,  A61K8/99 ,  A61K2800/10 ,  A61Q5/10 ,  C12N9/001 ,  C12Y103/03005

摘要： The problem is to provide a means for effectively dyeing keratin fibers while retaining high safety. Provided are a dyeing method and a dyeing agent, which include a combination of an oxidation dyeing agent consisting of an indole analogue and a bilirubin oxidase derived from Myrothecium verrucaria or Bacillus Subtilis.

摘要翻译： 问题在于提供有效染色角蛋白纤维同时保持高安全性的手段。 提供了一种染色方法和染色剂，其包括由吲哚类似物组成的氧化染色剂和源自疟原虫或枯草芽孢杆菌的胆红素氧化酶的组合。

公开(公告)号：US4748161A

公开(公告)日：1988-05-31

申请号：US739183

申请日：1985-05-30

申请人： Goro Kimura ,  Yoshihiko Hirose ,  Kumi Yoshida ,  Fumio Kuzuya ,  Katsunari Fujita

发明人： Goro Kimura ,  Yoshihiko Hirose ,  Kumi Yoshida ,  Fumio Kuzuya ,  Katsunari Fujita

IPC分类号： C07J53/00 ,  C07J9/00

CPC分类号： C07J53/004

摘要： A triterpenyl ester of organic acid other than triterpenyl esters of ferulic acid and of monobasic and dibasic saturated fatty acids. A process for producing a triterpenyl ester of organic acid other than esters of ferulic acid and of monobasic and dibasic saturated fatty acids, which comprises the reaction of a triterpenyl alcohol with an acid halide of the corresponding organic acid. A pharmaceutical composition for treatment of hyperlipidemia comprising a pharmaceutical carrier and an effective amount of a triterpenyl ester of organic acid other than triterpenyl esters of dibasic saturated fatty acids. A pharmaceutical composition for treating hyperlipidemia which comprises a pharmaceutical carrier and an effective amount of cyclobranol as an active ingredient.

摘要翻译： 除了阿魏酸和一元和二元饱和脂肪酸的三萜烯酯以外的有机酸的三萜烯酯。 一种制备除阿魏酸和一元和二元饱和脂肪酸以外的有机酸三萜烯酯的方法，其包括三萜烯醇与相应有机酸的酰卤反应。 一种用于治疗高脂血症的药物组合物，其包含药物载体和有效量的除二元饱和脂肪酸的三萜烯酯之外的有机酸的三萜烯基酯。 一种用于治疗高脂血症的药物组合物，其包含药物载体和有效量的环唑啉作为活性成分。

公开(公告)号：US5625597A

公开(公告)日：1997-04-29

申请号：US627126

申请日：1996-04-03

申请人： Yoshihiko Hirose

发明人： Yoshihiko Hirose

IPC分类号： G11C11/406 ,  G11C11/401 ,  G11C11/403 ,  G11C11/409 ,  G11C29/00 ,  G11C29/02 ,  G11C29/08 ,  G11C29/50

CPC分类号： G11C29/02

摘要： According to the present invention, there is provided a circuit structure capable of carrying out the function test of the refresh counter and the measurement of the counter cycle at the time of the refresh operation. The counter generates a refresh row address. The bit line sense amplifier circuit connected to a bit line pair for transmitting data of a memory cell, consists of the N-channel sense amplifier and the P-channel sense amplifier. The sense amplifier driving circuit supplies respective driving signals for the N-channel sense amplifier and the P-channel sense amplifier. The test control circuit is provided for carrying out the function test of the refresh counter and the measurement of the counter cycle at the time of the refresh operation, and controls the driving signals so as to set one of the N-channel sense amplifier and the P-channel sense amplifier in a non-active state at the time of a test mode.

摘要翻译： 根据本发明，提供了一种电路结构，其能够执行刷新计数器的功能测试和刷新操作时的计数器周期的测量。 计数器生成刷新行地址。 连接到用于发送存储单元的数据的位线对的位线读出放大器电路由N沟道读出放大器和P沟道读出放大器组成。 读出放大器驱动电路为N沟道读出放大器和P沟道读出放大器提供相应的驱动信号。 测试控制电路用于在刷新操作时执行刷新计数器的功能测试和计数器周期的测量，并且控制驱动信号以便设置N沟道读出放大器和 在测试模式时处于非活动状态的P通道读出放大器。

公开(公告)号：US5017969A

公开(公告)日：1991-05-21

申请号：US357778

申请日：1989-05-30

申请人： Tatsuo Mitomi ,  Yoshihiko Hirose

发明人： Tatsuo Mitomi ,  Yoshihiko Hirose

IPC分类号： G03G15/01 ,  G03G15/16

CPC分类号： G03G15/1655 ,  G03G15/0131

摘要： A device having a movable belt for transporting, for example, a recording medium, at least one rotary body around which the belt is wound so as to be supported thereon, and limiting portions or members for limiting the movement of the belt in the axial direction of the rotary body. The device is designed to stabilize the movement of the belt by making the friction between the limiting members smaller than the friction between the belt and the rotary body.

摘要翻译： 一种具有用于输送例如记录介质的可移动带的装置，至少一个旋转体，所述至少一个旋转体围绕所述带卷绕以便被支撑在所述旋转体上，以及用于限制所述带在轴向上的运动的限制部分或部件 的旋转体。 该装置被设计成通过使限制构件之间的摩擦小于带和旋转体之间的摩擦来稳定带的移动。

公开(公告)号：US4937664A

公开(公告)日：1990-06-26

申请号：US274982

申请日：1988-11-22

申请人： Kazuyoshi Chiku ,  Tomohiro Aoki ,  Yasushi Murayama ,  Yoshihiko Hirose ,  Takashi Uchida ,  Kunihiko Matsuzawa ,  Kazunori Kanekura

发明人： Kazuyoshi Chiku ,  Tomohiro Aoki ,  Yasushi Murayama ,  Yoshihiko Hirose ,  Takashi Uchida ,  Kunihiko Matsuzawa ,  Kazunori Kanekura

IPC分类号： G03G15/01 ,  H04N1/047 ,  H04N1/113 ,  H04N1/12 ,  H04N1/29 ,  H04N1/50

CPC分类号： H04N1/506 ,  G03G15/0194 ,  H04N1/047 ,  G03G2215/0119 ,  H04N1/1135 ,  H04N1/12 ,  H04N2201/04729 ,  H04N2201/04789 ,  H04N2201/04791

摘要： An image forming apparatus has a plurality of image forming stations capable of forming different images which are to be correctly registered and superimposed. Elimination of possible image misregistration in each image station is executed on the basis of the result of detection of register marks which are formed by each image forming station. The correction is executed at a timing which is independent from image forming sequences performed by each imgae forming station in accordance with image signals, e.g., during warming-up of the apparatus after the initial application of the power immediately after the input of image forming operation start instruction through a start key, or after completion of production of a predetermined number of copies counted from the last misregistration correcting operation.

公开(公告)号：US5097164A

公开(公告)日：1992-03-17

申请号：US458549

申请日：1989-12-28

申请人： Mikio Nakasugi ,  Yoshiaki Watanabe ,  Yoshihiko Hirose

发明人： Mikio Nakasugi ,  Yoshiaki Watanabe ,  Yoshihiko Hirose

IPC分类号： F16C33/10 ,  H02K5/10 ,  H02K5/16 ,  H02K29/08

CPC分类号： F16C33/10 ,  H02K29/08 ,  H02K5/10 ,  H02K5/1677

摘要： A motor supported by a dynamic pressure fluid bearing supporting a rotatable member by the dynamic pressure of fluid created by rotation is hermetically sealed with respect to the outside. The motor further includes a fixed shaft with the grooves and a rotatable sleeve. The rotatable sleeve is engageable with the fixed shaft and an optical member are mounted on the rotatable shaft.

摘要翻译： 由通过由旋转产生的流体的动态压力支撑可旋转构件的动态压力流体轴承支撑的电​​动机相对于外部气密地密封。 马达还包括具有凹槽的固定轴和可旋转的套筒。 可旋转套筒可与固定轴接合，光学构件安装在旋转轴上。

公开(公告)号：US4903067A

公开(公告)日：1990-02-20

申请号：US187078

申请日：1988-04-27

申请人： Yasushi Murayama ,  Osamu Hoshino ,  Kazuyoshi Chiku ,  Yukio Sato ,  Yoichi Kubota ,  Ken Miyagi ,  Yoshihiko Hirose ,  Kunihiko Matsuzawa ,  Hiroyuki Miyake ,  Tomohiro Aoki ,  Takashi Uchida ,  Kazunori Kanekura

发明人： Yasushi Murayama ,  Osamu Hoshino ,  Kazuyoshi Chiku ,  Yukio Sato ,  Yoichi Kubota ,  Ken Miyagi ,  Yoshihiko Hirose ,  Kunihiko Matsuzawa ,  Hiroyuki Miyake ,  Tomohiro Aoki ,  Takashi Uchida ,  Kazunori Kanekura

IPC分类号： G03G15/01 ,  G03G15/16 ,  H04N1/047 ,  H04N1/113 ,  H04N1/12 ,  H04N1/50

CPC分类号： H04N1/047 ,  G03G15/0194 ,  G03G15/1655 ,  H04N1/506 ,  G03G15/0189 ,  G03G2215/0119 ,  G03G2215/0141 ,  H04N1/1135 ,  H04N1/12 ,  H04N2201/04729 ,  H04N2201/04789

摘要： There is provided a multiimage forming apparatus for forming image data onto photo sensitive drums by an electrophotographic system. This apparatus comprises: an image forming circuit to form different images onto the photo sensitive drums; a transfer device to transfer the images on the drums onto the same transfer paper; a conveying belt to convey the transfer paper; a control circuit to control the image forming circuit so as to form registration marks to match the positions of the images onto the drums; CCD detectors to detect the recording positions of the marks; and a correcting circuit to correct at least two of the positional direction in the conveying direction of the belt, the positional deviation in the direction perpendicular to the belt conveying direction, the magnification of the image, and the inclination of the image on the basis of the detection outputs of the detectors. With this apparatus, the positional deviations of the images which occur during the image formation can be accurately corrected, so that the images can be accurately formed on the transfer paper by reading and matching the position matching registration marks.