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公开(公告)号：US20080011691A1
公开(公告)日：2008-01-17
申请号：US11569901
申请日：2005-06-09
申请人： Yukihiro Yamada , Yukihiko Uchi
发明人： Yukihiro Yamada , Yukihiko Uchi
CPC分类号： B01D39/1623 , A61M1/3633 , A61M2202/0439
摘要： A leukocyte-removing filter, characterized in that it comprises a filter material having a vertical permeation coefficient (kx) of 0.5×10−12 to 2.0×10−12 m2 and a ratio (ky/kx) of a horizontal permeation coefficient (ky) to kx of 0.5 to 1.5; and a method for removing leukocytes using said filter. The above leukocyte-removing filter has a higher leukocyte-removing performance per unit volume and also does not bring clogging nor increase of pressure drop.
摘要翻译： 1.一种去除白细胞的过滤器，其特征在于，它包括一种具有0.5×10 -1 -22×10 12 -12小时的垂直透过系数（kx）的过滤材料， 2和水平渗透系数（ky）与kx之间的比率（ky / kx）为0.5至1.5; 以及使用所述过滤器去除白细胞的方法。 上述白细胞去除过滤器每单位体积具有更高的白细胞去除性能，并且也不会引起堵塞，也不会增加压降。
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公开(公告)号：US08900462B2
公开(公告)日：2014-12-02
申请号：US11569901
申请日：2005-06-09
申请人： Yukihiro Yamada , Yukihiko Uchi
发明人： Yukihiro Yamada , Yukihiko Uchi
CPC分类号： B01D39/1623 , A61M1/3633 , A61M2202/0439
摘要： A leukocyte-removing filter, characterized in that it comprises a filter material having a vertical permeation coefficient (kx) of 0.5×10−12 to 2.0×10−12 m2 and a ratio (ky/kx) of a horizontal permeation coefficient (ky) to kx of 0.5 to 1.5; and a method for removing leukocytes using said filter. The above leukocyte-removing filter has a higher leukocyte-removing performance per unit volume and also does not bring clogging nor increase of pressure drop.
摘要翻译： 1.一种去除白细胞的过滤器，其特征在于，其具有纵向渗透系数（kx）为0.5×10-12〜2.0×10-12m 2的过滤材料和水平渗透系数（ky）的比率（ky / kx） ）至kx为0.5至1.5; 以及使用所述过滤器去除白细胞的方法。 上述白细胞去除过滤器每单位体积具有更高的白细胞去除性能，并且也不会引起堵塞，也不会增加压降。
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公开(公告)号：US08496826B2
公开(公告)日：2013-07-30
申请号：US10553950
申请日：2004-04-23
CPC分类号： B01D63/02 , A61M1/16 , A61M2202/0498 , A61M2205/15 , B01D63/021 , B01D2313/14 , B01D2313/20
摘要： A hollow fiber membrane type fluid treatment device having at least a body portion of tubular housing containing a hollow fiber membrane bundle. In the hollow fiber membrane type fluid treatment device, an inner surface of a body portion of the tubular housing at a side of a treatment liquid inlet has a body straight portion and an end tapered portion which increases in diameter toward an end face of the housing body portion, the hollow fiber membrane is arranged so that a distance between the hollow fiber membranes is gradually increased toward the end face on the treatment liquid inlet side along a taper of a tapered portion of the inner surface of the housing body portion, and a liquid to be treated flows within the hollow fiber membranes and a treatment liquid flows outside of the hollow fiber membranes.
摘要翻译： 一种中空纤维膜型流体处理装置，其至少具有包含中空纤维膜束的管状壳体的主体部分。 在中空纤维膜型流体处理装置中，管状壳体在处理液入口侧的主体部分的内表面具有主体直线部分和朝向壳体的端面直径增大的端部锥形部分 中空纤维膜被布置成使得中空纤维膜之间的距离沿着壳体主体部分的内表面的锥形部分的锥度朝着处理液入口侧的端面逐渐增大，并且 待处理的液体在中空纤维膜内流动，处理液体流过中空纤维膜外。
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公开(公告)号：US07597806B2
公开(公告)日：2009-10-06
申请号：US11915045
申请日：2006-05-22
申请人： Yukihiko Uchi , Takeshi Sukegawa
发明人： Yukihiko Uchi , Takeshi Sukegawa
CPC分类号： A61M1/16 , A61M1/1631 , A61M1/3606 , A61M1/3646
摘要： A body fluid treating filter device capable of maintaining its treating pressure within a clinically safe pressure range even if body fluid treatment is performed over a long period and having excellent property for recovering a body fluid after the body fluid treatment is completed. A body fluid treating cylindrical filter layer is stored in a cylindrical container having two body fluid flow ports. The cylindrical filter layer is disposed so that the inner space of a container can be divided into two parts by making its both end parts fluid-tight and fixing at least one of these both end parts to the inner wall surface of the container. One of the inner spaces of the container divided by the cylindrical filter layer is allowed to communicate with the first body fluid flow port and the other of the inner spaces of the container divided by the cylindrical filter layer is allowed to communicate with the second body fluid flow port. The body fluid treating cylindrical filter device is characterized in that a bar-like flow passage resistant member extending along the center axis is installed in the hollow part of the cylindrical filter layer, and a spacer layer for flowing the body fluid of 0.7 to 3.5 mm in thickness is formed between the outer peripheral surface of the cylindrical filter layer and the container and between the inner peripheral surface of the cylindrical filter layer and the flow passage resistance member.
摘要翻译： 即使长时间进行体液处理，并且在体液处理完成后具有优异的体液回收性能，能够将其处理压力维持在临床安全的压力范围内的体液处理过滤装置。 体液处理圆筒形过滤层被储存在具有两个体液流动口的圆筒形容器中。 圆柱形过滤层被设置成使得容器的内部空间通过使其两端部流体密封而分成两部分，并将这两个端部中的至少一个固定到容器的内壁表面。 通过圆柱形过滤层分隔的容器的内部空间之一被允许与第一体液流动口连通，并且由圆柱形过滤层分隔的容器的内部空间中的另一个允许与第二体液 流量端口。 体液处理圆柱形过滤装置的特征在于，沿着中心轴延伸的棒状流道阻力构件安装在圆筒形过滤层的中空部分中，并且用于使体液流动0.7至3.5mm的间隔层 在筒状过滤层的外周面与容器之间以及筒状过滤层的内周面与流路阻力部件之间形成有厚度。
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公开(公告)号：US20070007193A1
公开(公告)日：2007-01-11
申请号：US10553950
申请日：2004-04-23
IPC分类号： B01D63/02
CPC分类号： B01D63/02 , A61M1/16 , A61M2202/0498 , A61M2205/15 , B01D63/021 , B01D2313/14 , B01D2313/20
摘要： An object of the present invention is to provide a hollow fiber membrane type body fluid treatment device having very high substance removal performance which was not sufficiently achieved in a prior art and allowing the effective prevention of damage to hollow fiber membrane end portion due to impact by falling or impact by water flow. The hollow fiber membrane type body fluid treatment device comprising a hollow fiber membrane type body fluid treatment module comprising at least a tubular housing charged with a hollow fiber membrane bundle having resin layer fixed the bundle with a resin composition at both ends thereof and connection ports for a treatment liquid inlet and outlet formed in the outer peripheral surface of the tubular housing near both ends thereof and header caps provide with connection ports for a treatment target liquid fitted to both ends of the tubular housing. The hollow fiber membrane type fluid treatment device is characterized in that the device has a diameter-expanding portion allowing hollow fiber membranes to be placed so that distances between the hollow fiber membranes can be gradually increased toward the end face of the treatment liquid inlet on the inner surface of the tubular housing at the inlet side of the treatment liquid.
摘要翻译： 本发明的目的是提供一种中空纤维膜型体液处理装置，其具有非常高的物质去除性能，其在现有技术中不能充分实现，并且能够有效地防止由于冲击而导致的中空纤维膜端部的损伤 坠落或水流冲击。 中空纤维膜型体液处理装置，其具有中空纤维膜型体液处理模块，所述中空纤维膜型体液处理模块至少包括带有中空纤维膜束的管状壳体，所述中空纤维膜束的树脂层在两端固定有树脂组合物， 靠近其两端形成在管状壳体的外周表面中的处理液入口和出口以及集管盖为装配在管状壳体两端的处理目标液体提供连接口。 中空纤维膜型流体处理装置的特征在于，该装置具有直径扩大部分，其允许放置中空纤维膜，使得中空纤维膜之间的距离可以逐渐增加到处理液入口的端面上 在处理液体的入口侧的管状壳体的内表面。
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公开(公告)号：US20090078636A1
公开(公告)日：2009-03-26
申请号：US11915045
申请日：2006-05-22
申请人： Yukihiko Uchi , Takeshi Sukegawa
发明人： Yukihiko Uchi , Takeshi Sukegawa
IPC分类号： A61M1/16
CPC分类号： A61M1/16 , A61M1/1631 , A61M1/3606 , A61M1/3646
摘要： A body fluid treating filter device capable of maintaining its treating pressure within a clinically safe pressure range even if body fluid treatment is performed over a long period and having excellent property for recovering a body fluid after the body fluid treatment is completed. A body fluid treating cylindrical filter layer is stored in a cylindrical container having two body fluid flow ports. The cylindrical filter layer is disposed so that the inner space of a container can be divided into two parts by making its both end parts fluid-tight and fixing at least one of these both end parts to the inner wall surface of the container. One of the inner spaces of the container divided by the cylindrical filter layer is allowed to communicate with the first body fluid flow port and the other of the inner spaces of the container divided by the cylindrical filter layer is allowed to communicate with the second body fluid flow port. The body fluid treating cylindrical filter device is characterized in that a bar-like flow passage resistant member extending along the center axis is installed in the hollow part of the cylindrical filter layer, and a spacer layer for flowing the body fluid of 0.7 to 3.5 mm in thickness is formed between the outer peripheral surface of the cylindrical filter layer and the container and between the inner peripheral surface of the cylindrical filter layer and the flow passage resistance member.
摘要翻译： 即使长时间进行体液处理，并且在体液处理完成后具有优异的体液回收性能，能够将其处理压力维持在临床安全的压力范围内的体液处理过滤装置。 体液处理圆筒形过滤层被储存在具有两个体液流动口的圆筒形容器中。 圆柱形过滤层被设置成使得容器的内部空间通过使其两端部流体密封而分成两部分，并将这两个端部中的至少一个固定到容器的内壁表面。 通过圆柱形过滤层分隔的容器的内部空间之一被允许与第一体液流动口连通，并且由圆柱形过滤层分隔的容器的内部空间中的另一个允许与第二体液 流量端口。 体液处理圆柱形过滤装置的特征在于，沿着中心轴延伸的棒状流道阻力构件安装在圆筒形过滤层的中空部分中，并且用于使体液流动0.7至3.5mm的间隔层 在筒状过滤层的外周面与容器之间以及筒状过滤层的内周面与流路阻力部件之间形成有厚度。
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公开(公告)号：US07438821B2
公开(公告)日：2008-10-21
申请号：US10474805
申请日：2002-04-02
申请人： Tomohisa Yokomizo , Yukihiko Uchi
发明人： Tomohisa Yokomizo , Yukihiko Uchi
CPC分类号： A61M1/3636 , A61M1/0222 , A61M1/0231 , A61M1/3633
摘要： A filtering method which prevents adhesion between an outlet vessel and a filter element and which uses a flexible filter which allows smooth flow of liquid and is superior in filtering performance; and a filtering system. A filtering method which uses a flexible vessel having an inlet and an outlet for liquid, a sheet-like filter element, and a filter in which the inlet and outlet for liquid are separated by the filter element, wherein in filtering a liquid by the action of gravity or of a liquid feed pump, the pressure in the outlet of the filter is not less than 0 mmHg with respect to the atmospheric pressure; and a filtering system. Further, a filtering method in which a suitable combination of the filter and the hydrodynamic characteristics of the flow channel upstream or downstream of the filter is selected to make the pressure in the outlet of the filter not less than 0 mmHg with respect to the atmospheric pressure; and a filtering system.
摘要翻译： 一种防止出口容器和过滤元件之间的粘合并且使用柔性过滤器的过滤方法，其允许液体流畅并且过滤性能优异; 和过滤系统。 一种过滤方法，其使用具有用于液体的入口和出口的柔性容器，片状过滤元件和过滤器，其中用于液体的入口和出口由过滤器元件分离，其中通过动作过滤液体 的重力或液体供给泵，过滤器的出口压力相对于大气压不小于0mmHg; 和过滤系统。 此外，选择过滤器的过滤器和过滤器的上游或下游的流体流动特性的适当组合以使过滤器的出口中的压力相对于大气压力不小于0mmHg的过滤方法 ; 和过滤系统。
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