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    ORAL COMPOSITION FOR ALLEVIATING ULTRAVIOLET IRRADIATION-INDUCED DAMAGE
    1.
    发明申请
    ORAL COMPOSITION FOR ALLEVIATING ULTRAVIOLET IRRADIATION-INDUCED DAMAGE 审中-公开
    用于治疗超紫外线辐射诱导性损伤的口腔组合物

    公开(公告)号：US20120189563A1

    公开(公告)日：2012-07-26

    申请号：US13261161

    申请日：2010-03-31

    申请人： Yutaka Ashida ,  Yosuke Tojo ,  Chieko Mizumoto ,  Masashi Mita ,  Shoichiro Shimada

    发明人： Yutaka Ashida ,  Yosuke Tojo ,  Chieko Mizumoto ,  Masashi Mita ,  Shoichiro Shimada

    IPC分类号： A61K31/197 ,  A61P17/12 ,  A61Q19/02 ,  A61Q19/08 ,  A61P27/12 ,  A61K8/44 ,  A61P17/00 ,  A61P35/00

    CPC分类号： A61K31/198 ,  A21D2/245 ,  A23L33/175 ,  A23V2002/00 ,  A61K8/447 ,  A61K2800/92 ,  A61Q17/04 ,  A61Q19/08 ,  A23V2200/318 ,  A23V2250/06

    摘要： Disclosed are: an oral composition for alleviating ultraviolet irradiation-induced damage, which can be used on a daily basis and is stable and safe; and a medicinal agent; and anti-wrinkle agent and a food composition, each of which comprises the oral composition. Specifically disclosed is an oral composition for alleviating ultraviolet irradiation-induced damage, which comprises at least one compound selected from the group consisting of methionine and derivatives and/or salts thereof. The composition may be an anti-wrinkle agent, a pharmaceutical composition for treating and/or preventing skin diseases, a food composition, or a pharmaceutical composition for preventing or treating cataract. In the oral composition for alleviating ultraviolet irradiation-induced damage, methionine may be in the D-form.

    摘要翻译： 公开了一种用于减轻紫外线照射引起的损伤的口服组合物，其可以每天使用并且是稳定和安全的; 和药剂; 和抗皱剂和食品组合物，其各自包含口腔组合物。 具体公开了一种用于减轻紫外线照射诱发的损伤的口服组合物，其包含至少一种选自甲硫氨酸及其衍生物和/或盐的化合物。 组合物可以是抗皱剂，用于治疗和/或预防皮肤病的药物组合物，食品组合物或用于预防或治疗白内障的药物组合物。 在用于减轻紫外线照射诱发的损伤的口服组合物中，甲硫氨酸可以是D-型。

    ANTIOXIDANT COMPOSITION
    6.
    发明申请
    ANTIOXIDANT COMPOSITION 有权
    抗氧化剂组合物

    公开(公告)号：US20120184620A1

    公开(公告)日：2012-07-19

    申请号：US13261240

    申请日：2010-03-31

    申请人： Yosuke Tojo ,  Chieko Mizumoto ,  Yutaka Ashida ,  Masashi Mita

    发明人： Yosuke Tojo ,  Chieko Mizumoto ,  Yutaka Ashida ,  Masashi Mita

    IPC分类号： A61K31/198 ,  A61P35/00 ,  A61P27/12 ,  A61P17/00

    CPC分类号： A23L1/3051 ,  A23L33/175 ,  A23V2002/00 ,  A61K8/44 ,  A61K31/198 ,  A61K45/06 ,  A61K2800/522 ,  A61Q19/007 ,  A61Q19/08 ,  A61K2300/00 ,  A23V2200/318 ,  A23V2250/06

    摘要： Disclosed is a stable and safe antioxidant composition which can be used routinely. Specifically disclosed is an antioxidant composition which contains one or more compounds selected from the group consisting of D-aspartic acid, derivatives and/or salts thereof. The composition may be used for the purpose of suppressing and/or improving skin conditions. The skin conditions may include, but is not limited to, fine wrinkles, a rough skin, a dry skin, a skin cancer, a skin allergy, an inflammation of the skin and a photosensitive dermatosis. The composition may be used for an external preparation for the skin, a food, and a pharmaceutical product for cataract.

    摘要翻译： 公开了可以常规使用的稳定且安全的抗氧化剂组合物。 具体公开的是含有一种或多种选自D-天冬氨酸，其衍生物和/或盐的化合物的抗氧化剂组合物。 该组合物可用于抑制和/或改善皮肤状况。 皮肤状况可以包括但不限于细皱纹，粗糙皮肤，干性皮肤，皮肤癌，皮肤过敏，皮肤炎症和感光性皮肤病。 该组合物可用于皮肤外用制剂，食品和白内障药用制品。

    COMPOSITION FOR ALLEVIATING ULTRAVIOLET IRRADIATION-INDUCED DAMAGE
    7.
    发明申请
    COMPOSITION FOR ALLEVIATING ULTRAVIOLET IRRADIATION-INDUCED DAMAGE 审中-公开
    用于治疗超紫外线辐射诱导的损伤的组合物

    公开(公告)号：US20120148509A1

    公开(公告)日：2012-06-14

    申请号：US13261182

    申请日：2010-09-14

    申请人： Yutaka Ashida ,  Yosuke Tojo ,  Chieko Mizumoto ,  Masashi Mita

    发明人： Yutaka Ashida ,  Yosuke Tojo ,  Chieko Mizumoto ,  Masashi Mita

    IPC分类号： A61K31/198 ,  A61K31/42 ,  A61P17/00 ,  A61K8/49 ,  A61Q19/00 ,  A61Q17/04 ,  A61P27/12 ,  A61K8/44 ,  A61P35/00

    CPC分类号： A61Q17/04 ,  A23L33/175 ,  A23V2002/00 ,  A61K8/0208 ,  A61K8/44 ,  A61K9/0014 ,  A61K9/107 ,  A61K9/12 ,  A61K9/2018 ,  A61K9/4858 ,  A61K9/7007 ,  A61K31/198 ,  A61Q19/004 ,  A61Q19/08 ,  A23V2200/318 ,  A23V2250/0632 ,  A23V2250/0642

    摘要： Disclosed are a composition for alleviating ultraviolet irradiation-induced damage, which is stable and safe and can be used on a daily basis, and a pharmaceutical composition, an external skin preparation, a food composition and a medicine for cataract, each comprising aforesaid composition for alleviating ultraviolet irradiation-induced damage. Specifically disclosed is a composition for alleviating ultraviolet irradiation-induced damage which contains one or more kinds of compounds selected from the group consisting of methionine, D-serine and derivatives and/or salts of the same. The aforesaid composition may be an external preparation for the skin, an anti-wrinkle agent, a sunscreen agent, a medicinal composition for treating and/or preventing skin diseases, a food composition or a pharmaceutical product for cataract. In the aforesaid composition for alleviating ultraviolet irradiation-induced damage, the aforesaid methionine may be D-methionine, and the aforesaid D-serine derivative may be D-cycloserine.

    摘要翻译： 公开了一种缓和紫外线照射诱发的损伤的组合物，其是稳定和安全的并且可以每天使用，以及药物组合物，外用皮肤制剂，食品组合物和白内障药物，其各自包含上述组合物 缓解紫外线照射引起的损伤。 具体公开了含有选自甲硫氨酸，D-丝氨酸及其衍生物和/或其盐的一种或多种化合物的减轻紫外线照射诱发的损伤的组合物。 上述组合物可以是用于皮肤的外用制剂，抗皱剂，防晒剂，用于治疗和/或预防皮肤病的药物组合物，食品组合物或白内障药物。 在上述减轻紫外线照射诱发损伤的组合物中，上述甲硫氨酸可以是D-甲硫氨酸，上述D-丝氨酸衍生物可以是D-环丝氨酸。

    SKIN-WHITENING AGENT AND COSMETIC METHOD FOR WHITENING SKIN
    9.
    发明申请
    SKIN-WHITENING AGENT AND COSMETIC METHOD FOR WHITENING SKIN 审中-公开
    用于白化皮肤的皮肤白化剂和化妆方法

    公开(公告)号：US20120122951A1

    公开(公告)日：2012-05-17

    申请号：US13138787

    申请日：2010-03-04

    申请人： Rikako Suzuki ,  Yosuke Tojo ,  Chieko Mizumoto ,  Kiyotaka Hasegawa ,  Yutaka Ashida ,  Jun-ichi Hosoi ,  Kiyoshi Sato

    发明人： Rikako Suzuki ,  Yosuke Tojo ,  Chieko Mizumoto ,  Kiyotaka Hasegawa ,  Yutaka Ashida ,  Jun-ichi Hosoi ,  Kiyoshi Sato

    IPC分类号： A61K31/40 ,  A61Q19/02 ,  C07D207/16

    CPC分类号： A61K31/401 ,  A23L33/175 ,  A23V2002/00 ,  A61K8/0212 ,  A61K8/0216 ,  A61K8/4913 ,  A61K2800/92 ,  A61Q19/02 ,  A23V2200/318

    摘要： The development of a skin-whitening agent which has a lower molecular weight, can be synthesized through a fewer steps and can be produced at low cost has been demanded. Thus, it is provided by the present invention a skin-whitening agent including one or more compounds selected from the group consisting of 4-cis-hydroxyproline and its derivative and/or its salt, a skin-whitening composition for external formulation to the skin, a cosmetic composition and a pharmaceutical composition, each of which contains the skin-whitening agent of the invention, and a cosmetic method for whitening the skin, which includes a step of administering one or more compounds selected from the group consisting of 4-cis-hydroxyproline and its derivative and/or its salt. In the skin-whitening agent and the cosmetic method for whitening the skin of the invention, the 4-cis-hydroxyproline may be 4-cis-L-hydroxyproline and/or 4-cis-D-hydroxyproline.

    摘要翻译： 需要开发具有较低分子量的皮肤增白剂，可以通过较少的步骤合成并且可以以低成本生产。 因此，本发明提供一种皮肤增白剂，其包含一种或多种选自4-顺式 - 羟基脯氨酸及其衍生物和/或其盐的化合物，用于皮肤外用制剂的皮肤增白组合物 ，化妆品组合物和药物组合物，其含有本发明的皮肤增白剂和美白化妆品的方法，其包括给予一种或多种选自4-顺式 - 羟脯氨酸及其衍生物和/或其盐。 在本发明的皮肤美白剂和美白化妆品的美白方法中，4-顺式 - 羟基脯氨酸可以是4-顺式-L-羟基脯氨酸和/或4-顺式-D-羟基脯氨酸。

    ORAL COMPOSITION FOR REDUCING WRINKLE FORMATION
    10.
    发明申请
    ORAL COMPOSITION FOR REDUCING WRINKLE FORMATION 审中-公开
    用于减少皱纹形成的口腔组合物

    公开(公告)号：US20120190745A1

    公开(公告)日：2012-07-26

    申请号：US13393410

    申请日：2010-08-31

    申请人： Yutaka Ashida ,  Keiko Takada ,  Mihoshi Yokoo ,  Yosuke Tojo

    发明人： Yutaka Ashida ,  Keiko Takada ,  Mihoshi Yokoo ,  Yosuke Tojo

    IPC分类号： A61K31/198 ,  A61P17/00

    CPC分类号： A23C9/1322 ,  A21D2/245 ,  A23G3/44 ,  A23L7/20 ,  A23L11/09 ,  A23L27/50 ,  A23L27/60 ,  A23L33/175 ,  A23V2002/00 ,  A61K31/198 ,  A23V2200/302 ,  A23V2250/0618 ,  A23V2200/318

    摘要： Provided is a novel composition that acts to inhibit and/or ameliorate wrinkle formation, does not have adverse effects like those of retinoids, and is highly photostable. An oral composition for reducing wrinkle formation and an oral composition for preventing wrinkle formation are provided, the compositions containing at least one compound selected from the group consisting of D-glutamic acid and derivatives and/or salts thereof. Also provided are a pharmaceutical composition and a food composition containing the oral composition for reducing wrinkle formation or the oral composition for preventing wrinkle formation.

    摘要翻译： 提供了用于抑制和/或改善皱纹形成的新型组合物，不具有类似类维生素A的不利影响，并且是高度光稳定的。 提供了用于减少皱纹形成的口腔组合物和用于防止皱纹形成的口腔组合物，所述组合物含有至少一种选自D-谷氨酸及其衍生物和/或盐的化合物。 还提供了含有用于减少皱纹形成的口腔组合物的药物组合物和食品组合物或用于防止皱纹形成的口腔组合物。