-
公开(公告)号:US20080085891A1
公开(公告)日:2008-04-10
申请号:US11986863
申请日:2007-11-26
申请人: Zice Fu , Alan Huang , Jiwen Liu , Julio Medina , Michael Schmitt , H. Tang , Yingcai Wang , Qingge Xu
发明人: Zice Fu , Alan Huang , Jiwen Liu , Julio Medina , Michael Schmitt , H. Tang , Yingcai Wang , Qingge Xu
IPC分类号: A61K31/27 , A61K31/196 , A61K31/381 , A61K31/415 , A61K31/44 , A61K31/47 , A61K31/5375 , A61K31/55 , A61P11/06 , A61P29/00 , A61P35/00 , A61P37/08
CPC分类号: C07C205/37 , C07C205/56 , C07C233/75 , C07C271/28 , C07C275/42 , C07C311/08 , C07C311/21 , C07C311/29 , C07C317/44 , C07C2601/04 , C07C2601/08 , C07D209/22 , C07D209/26 , C07D213/71 , C07D215/36 , C07D233/84 , C07D243/12 , C07D243/24 , C07D257/04 , C07D295/192 , C07D307/91 , C07D333/34 , C07D333/62
摘要: Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of inflammatory and immune-related diseases and conditions. In particular, the invention provides compounds which modulate the function and/or expression of proteins involved in atopic diseases, inflammatory conditions and cancer. The subject compounds are carboxylic acid derivatives.
摘要翻译: 提供了可用于治疗炎症和免疫相关疾病和病症的化合物,药物组合物和方法。 特别地,本发明提供调节参与特应性疾病,炎性病症和癌症的蛋白质的功能和/或表达的化合物。 主题化合物是羧酸衍生物。