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公开(公告)号：US09968519B2
公开(公告)日：2018-05-15
申请号：US14738442
申请日：2015-06-12
Applicant: ADVANCED SCIENTIFICS, INC.
Inventor： Rudolf Pavlik
CPC classification number: A61J1/16 , A01N1/0263 , A01N1/0268 , A61J1/10 , A61J1/1475 , B65D31/06 , F25D31/00
Abstract: A freezer bag, a storage system, and a method of freezing are provided. The freezer bag includes a pliable housing having opposing sides and bounding a cavity at least partially disposed between the opposing sides, each opposing side having an interior surface communicating with the cavity and an opposing exterior surface that is openly exposed, the pliable housing including a first panel and a seam. A first tufting couples together the opposing sides of the pliable housing at a distance spaced apart from the seam so that the cavity encircles the first tufting. A first port is connected to the pliable housing and communicates with the cavity.
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公开(公告)号：US20140083170A1
公开(公告)日：2014-03-27
申请号：US13974932
申请日：2013-08-23
Applicant: ADVANCED SCIENTIFICS, INC.
Inventor： Rudolf PAVLIK
IPC: G01M3/32
CPC classification number: G01M3/3218 , G01M3/3263
Abstract: A portable flexible container integrity test device for conducting integrity testing of flexible containers is disclosed. The test device is particularly useful for testing aseptic flexible film bags in a manner that maintains the sterile nature of the container and removes crinkles by inflating the containers to remove crinkles and establish an inflation set point. The test device includes a programmable logic controller (PLC), a pressure transducer in electronic communication with the PLC, a power source configured to provide electrical power to the PLC, a blower in electronic communication with the PLC, a gas delivery pathway in selective fluid communication with the blower, and a human/machine interface in electronic communication with the PLC. The device is portable and configured to fluidly connect to a flexible container via the gas delivery pathway.
Abstract translation: 公开了用于进行柔性容器的完整性测试的便携式柔性容器完整性测试装置。 测试装置特别适用于以保持容器的无菌性质的方式测试无菌柔性膜袋，并且通过使容器膨胀以除去皱纹并建立充气设定点来消除皱纹。 测试装置包括可编程逻辑控制器（PLC），与PLC电子通信的压力传感器，被配置为向PLC提供电力的电源，与PLC电子通信的鼓风机，选择性流体中的气体输送路径 与鼓风机的通信，以及与PLC电子通信的人机界面。 该装置是便携式的并且构造成经由气体输送路径流体地连接到柔性容器。
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公开(公告)号：US08534120B1
公开(公告)日：2013-09-17
申请号：US13615935
申请日：2012-09-14
Applicant: Rudolf Pavlik
Inventor： Rudolf Pavlik
IPC: G01M3/26
CPC classification number: G01M3/3218 , G01M3/3263
Abstract: A portable test device and related method are disclosed for conducting integrity testing of flexible containers. The test is particularly useful for testing aseptic flexible film bags in a manner that maintains the sterile nature of the container and removes crinkles by inflating the containers to remove crinkles and establish an inflation set point. The decay in pressure is measured over a predetermined period of time; if pressure loss does not exceed a predetermined threshold the integrity of the bag is confirmed and it can be filled without further manipulation of the container that may result in introducing flaws.
Abstract translation: 公开了用于进行柔性容器的完整性测试的便携式测试装置和相关方法。 该测试对于以保持容器的无菌性质的方式测试无菌柔性膜袋特别有用，并通过使容器膨胀以除去皱纹并建立充气设定点来消除皱纹。 在预定的时间段内测量压力衰减; 如果压力损失不超过预定阈值，则确认袋的完整性，并且可以在不进一步操纵可能导致缺陷的容器的情况下填充袋。
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公开(公告)号：US08281961B2
公开(公告)日：2012-10-09
申请号：US11753717
申请日：2007-05-25
Applicant: Carl Martin
Inventor： Carl Martin
IPC: B67D3/00
CPC classification number: B67D7/0294 , Y10T137/86501
Abstract: A device (10) and method for aseptically or non-aseptically accessing a fluid in a container (210) using an existing container opening (211). The device (10) includes a sanitary fitting (12) for attaching the device to the container over the existing container opening, and a sample coupling (14) associated with the sanitary fitting. The sanitary fitting (12) includes a first port (32), and the sample coupling (14) includes at least two second ports (52). The sample coupling (14) is rotatable relative to the sanitary fitting (12) in one direction to cause the first port (32) to successively align with each of the second ports (52), and thereby allows access to the fluid through the aligned first and second ports (32,52).
Abstract translation: 一种使用现有容器开口（211）无菌或非无菌地进入容器（210）中的流体的装置（10）和方法。 装置（10）包括用于将装置连接到现有容器开口上的容器的卫生用品（12）和与卫生配件相关联的样品联接器（14）。 卫生配件（12）包括第一端口（32），并且样品联接器（14）包括至少两个第二端口（52）。 样品联接器（14）可以在一个方向上相对于卫生配件（12）旋转，以使第一端口（32）与每个第二端口（52）连续对准，从而允许通过对准 第一和第二端口（32,52）。
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公开(公告)号：US08201594B2
公开(公告)日：2012-06-19
申请号：US12136412
申请日：2008-06-10
Applicant: Carl Martin
Inventor： Carl Martin
IPC: B65B3/04
CPC classification number: B65B39/004 , B65B55/00
Abstract: A system (10) and method for substantially automatically aseptically or non-aseptically filling a container with a fluid. The transfer of fluid occurs via a movable nozzle mechanism (20) substantially automatically inserted into a side opening (32) in a connector (12) attached to the container. More specifically, the side opening (32) in the connector (12) is exposed, the nozzle mechanism (20) is moved into the side opening (32), the fluid is transferred into the container via the nozzle mechanism (20) and the connector (12), the nozzle mechanism (20) is removed from the side opening (32) in the connector (12), and the side opening (32) in the connector (12) is closed. The aseptic transfer of fluid includes a substantially automatic sterilization procedure accomplished by both spray and contact components (54,56).
Abstract translation: 一种用于基本上自动无菌或非无菌地填充容器的流体系统（10）和方法。 流体的传送通过基本上自动插入连接到容器的连接器（12）中的侧开口（32）中的可移动喷嘴机构（20）发生。 更具体地，连接器（12）中的侧开口（32）露出，喷嘴机构（20）移动到侧开口（32）中，流体经由喷嘴机构（20）被转移到容器中，并且 连接器（12）中，喷嘴机构（20）从连接器（12）中的侧开口（32）移除，并且连接器（12）中的侧开口（32）关闭。 流体的无菌转移包括由喷雾和接触组分两者完成的基本上自动的灭菌程序（54,56）。
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Patent Agency Ranking
公开(公告)号：US07530374B2
公开(公告)日：2009-05-12
申请号：US11694365
申请日：2007-03-30
Applicant: Carl Martin
Inventor： Carl Martin
CPC classification number: B65B55/10 , B65B39/004 , Y10T137/4245
Abstract: A system (10) and method for substantially automatically aseptically or non-aseptically filling a container with a fluid. The transfer of fluid occurs via a movable nozzle mechanism (20) substantially automatically inserted into a side opening (32) in a connector (12) attached to the container. More specifically, the side opening (32) in the connector (12) is exposed, the nozzle mechanism (20) is moved into the side opening (32), the fluid is transferred into the container via the nozzle mechanism (20) and the connector (12), the nozzle mechanism (20) is removed from the side opening (32) in the connector (12), and the side opening (32) in the connector (12) is closed. The aseptic transfer of fluid includes a substantially automatic sterilization procedure accomplished by both spray and contact components (54,56).
Abstract translation: 一种用于基本上自动无菌或非无菌地填充容器的流体系统（10）和方法。 流体的传送通过基本上自动插入连接到容器的连接器（12）中的侧开口（32）中的可移动喷嘴机构（20）发生。 更具体地，连接器（12）中的侧开口（32）露出，喷嘴机构（20）移动到侧开口（32）中，流体经由喷嘴机构（20）被转移到容器中，并且 连接器（12）中，喷嘴机构（20）从连接器（12）中的侧开口（32）移除，并且连接器（12）中的侧开口（32）关闭。 流体的无菌转移包括由喷雾和接触组分两者完成的基本上自动的灭菌程序（54,56）。
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公开(公告)号：US20220054996A1
公开(公告)日：2022-02-24
申请号：US17521201
申请日：2021-11-08
Applicant: Advanced Scientifics, Inc.
Inventor： Rudolf Pavlik
Abstract: A mixing system includes a container having an encircling sidewall bounding a chamber and extending between an upper end and an opposing lower end; a support plate disposed within the chamber and secured to the encircling sidewall; an inner wall secured to the support plate and projecting within the chamber toward the upper end, an open space being formed between the inner wall and the encircling sidewall; and a first aperture extending through the encircling sidewall so as to communicate with the open space. A mixing assembly is positioned within the container and is supported on the support plate, the mixing assembly including a pliable enclosure and a mixing device.
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公开(公告)号：US10463571B2
公开(公告)日：2019-11-05
申请号：US16162125
申请日：2018-10-16
Applicant: ADVANCED SCIENTIFICS, INC.
Inventor： Rudolf Pavlik
Abstract: A bag assembly includes a first panel secured to a second panel by a seam so that a cavity is formed between the first panel and the second panel, the seam encircling the cavity. A first seal couples together the first panel and the second panel at a location spaced apart from the seam so that the cavity encircles the first seal. In one embodiment, the first seal can be circular. A first port communicates with the cavity.
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公开(公告)号：US10350562B2
公开(公告)日：2019-07-16
申请号：US15652487
申请日：2017-07-18
Applicant: ADVANCED SCIENTIFICS, INC.
Inventor： Rudolf Pavlik
Abstract: A mixing system includes a tank assembly and a container positioned within the tank assembly, the container bounding a compartment. A mixer is disposed within the compartment of the container. A shaft has a first end secured to the mixer and an opposing second end disposed outside of the container. An actuation mechanism is coupled with the second end of the shaft outside of the container and reciprocally moves the shaft and the mixer a stroke length, the stroke length being adjusted based on a pre-programmed protocol or signals from a sensor.
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公开(公告)号：US10111809B2
公开(公告)日：2018-10-30
申请号：US14875442
申请日：2015-10-05
Applicant: ADVANCED SCIENTIFICS, INC.
Inventor： Rudolf Pavlik
Abstract: A method for forming an aseptic connection includes inserting an end of a sealed fill connector into a receptacle of an aseptic connector assembly; moving a pivot portion of the aseptic connector assembly relative to a body portion of the aseptic connector assembly so as to sever a portion of the fill connector, the pivot portion being at least partially disposed within the body portion; and advancing a conduit portion of the aseptic connector assembly into the fill connector so as to form an aseptic connection therebetween, the conduit portion being at least partially disposed within the pivot portion or the body portion of the aseptic connector assembly after advancing.
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