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公开(公告)号:US12102643B2
公开(公告)日:2024-10-01
申请号:US18189613
申请日:2023-03-24
申请人: ANTARES PHARMA, INC.
发明人: Xiaoming Chen , Shaowei Ong
IPC分类号: A61K31/573 , A61K47/18 , A61K47/20
CPC分类号: A61K31/573 , A61K47/183 , A61K47/20
摘要: The present disclosure provides aqueous formulations comprising hydrocortisone sodium phosphate and monothioglycerol. In some embodiments, the formulations comprise monobasic sodium phosphate, dibasic sodium phosphate, or disodium EDTA. The present disclosure further provides a method of treating a disease or disorder in a subject by administering the aqueous formulation.
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公开(公告)号:US20240091239A1
公开(公告)日:2024-03-21
申请号:US18502166
申请日:2023-11-06
申请人: Antares Pharma, Inc.
IPC分类号: A61K31/568 , A61K9/00 , A61K9/08 , A61K9/10 , A61K47/10 , A61K47/44 , A61M5/20 , A61M5/30 , A61M5/32
CPC分类号: A61K31/568 , A61K9/0019 , A61K9/0021 , A61K9/08 , A61K9/10 , A61K47/10 , A61K47/44 , A61M5/2033 , A61M5/30 , A61M5/3204 , A61P5/26
摘要: The present invention provides compositions and methods for treating a subject in need of treatment with testosterone, including introducing testosterone into the subject subcutaneously, intradermally, or intramuscularly, from a needle assisted jet injection device.
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公开(公告)号:US11717610B2
公开(公告)日:2023-08-08
申请号:US16880451
申请日:2020-05-21
申请人: Antares Pharma, Inc.
CPC分类号: A61M5/2033 , A61M5/3146 , A61M5/3156 , A61M5/31536 , A61M5/31553 , A61M5/2053 , A61M5/3204 , A61M5/482 , A61M2005/2013 , A61M2005/2073 , A61M2005/3154 , A61M2207/00
摘要: An injection device for injecting medicament in a patient comprises a housing configured to house a fluid reservoir that has one of a plurality of volumes of medicament. An injection conduit fluidly coupled to the fluid reservoir defines a fluid pathway from the fluid reservoir to the patient. A firing mechanism is coupled to the fluid reservoir and is configured to expel the medicament from the fluid reservoir through the injection conduit. A volume setting mechanism is coupled to the firing mechanism and is configured to select the one of the plurality of volumes of medicament for the firing mechanism to expel. A dose setting mechanism is configured to select all or a fraction of the one of the plurality of volumes of medicament that is injected from the injection conduit when the firing mechanism is actuated.
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公开(公告)号:US20230191031A1
公开(公告)日:2023-06-22
申请号:US18169774
申请日:2023-02-15
申请人: Antares Pharma, Inc.
发明人: James W. LANNAN , Julius C. SUND
CPC分类号: A61M5/2033 , A61M5/50 , A61M2005/3267
摘要: A jet injector that includes a prefilled syringe. The syringe includes a fluid chamber that contains a medicament. The syringe also has an injection-assisting needle, and a plunger is movable within the fluid chamber. A housing is configured for allowing insertion of the needle to a penetration depth. The housing includes a retractable guard and an interference component, e.g., a lock ring, adjacent to the retractable guard that interferes with the movement of the retractable guard. An energy source is configured for biasing the plunger to produce an injecting pressure to jet inject the medicament from the fluid chamber through the needle to an injection site.
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公开(公告)号:US11628260B2
公开(公告)日:2023-04-18
申请号:US16797447
申请日:2020-02-21
申请人: ANTARES PHARMA, INC.
发明人: Patrick Madsen , Hans Pflaumer , Kevin Swanson
IPC分类号: A61M5/315
摘要: A dispensing mechanism for delivering a dosage of medicament including a housing, a push button, a crank arm that is slideably engageable with the push button, a ram, and a ratchet gear releasably engageable with the crank arm and ram, translation of the push button along an axis causing the crank arm to engage and rotate the ratchet gear which causes the ram to distally advance relative to the housing.
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公开(公告)号:US20210308380A1
公开(公告)日:2021-10-07
申请号:US17262676
申请日:2019-07-24
申请人: Antares Pharma, Inc.
发明人: Michael Travanty , Steven W. Mattix
IPC分类号: A61M5/20 , A61M5/32 , A61K31/485
摘要: An injector including: a housing, a cap detachably coupled to the housing, a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly including a trigger engagement member, an energy source associated with the ram for powering the ram to expel medicament from the medicament container, a trigger member disposed about an axis, the trigger member moveable between a pre-firing configuration and a firing configuration, wherein medicament is expelled from the medicament container when the trigger member is in the firing configuration, a needle guard moveably coupled to the housing, the needle guard movable between a storage position and a pre-injection position, wherein the needle guard moves from the storage position to the pre-injection position as the cap is detached from the housing.
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公开(公告)号:US11058824B2
公开(公告)日:2021-07-13
申请号:US16389336
申请日:2019-04-19
申请人: Antares Pharma, Inc.
摘要: A medicament dispensing mechanism is disclosed that is configured to eject successive doses of the medicament from a medicament chamber. An embodiment of the dispensing mechanism includes a housing and a plunger rod configured for ejecting the doses of medicament from the chamber. The dispensing mechanism further includes an actuation mechanism that comprises a trigger associated with the housing and having a ready and a fired position with respect thereto. The trigger is configured for manipulation by a user for successive movement in a generally axial dosing motion from the ready position to the fired position in which the trigger is associated with the plunger rod to cause the plunger rod to eject one of the doses of a predetermined volume and a resetting motion from the fired position to the ready position that comprises axial rotation, wherein the trigger is uncoupled from the plunger rod during the resetting motion.
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公开(公告)号:US20210015741A1
公开(公告)日:2021-01-21
申请号:US17062196
申请日:2020-10-02
申请人: Antares Pharma, Inc.
发明人: Paul K. Wotton , Kaushik J. Dave , John W. Hayes , Peter L. Sadowski , Hermanus L. Jooste , Jonathan Jaffe
IPC分类号: A61K9/00 , A61M5/20 , A61M5/30 , A61M5/32 , A61K31/568 , A61M37/00 , A61K31/56 , A61M5/00 , A61M5/315 , A61M5/42 , A61M5/44
摘要: The present invention provides compositions and methods for treating a subject in need of treatment with testosterone, including introducing testosterone into the subject subcutaneously, intradermally, or intramuscularly, from a needle assisted jet injection device.
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公开(公告)号:US10881798B2
公开(公告)日:2021-01-05
申请号:US15783407
申请日:2017-10-13
申请人: Antares Pharma, Inc.
发明人: Michael Travanty
摘要: An injector includes a trigger mechanism including: a trigger member disposed about an axis having an aperture and a protrusion, and a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly further having a trigger engagement member configured to engage the aperture of the trigger member when the trigger member is in a pre-firing condition; an energy source associated with the ram for powering the ram to expel the medicament; and a user-operable firing-initiation member having an aperture engaged with the protrusion of the trigger member and operable for causing an axial translation of the trigger member in a proximal direction from the pre-firing condition to a firing condition in which the trigger engagement member is released from the retaining portion to allow the energy source to fire the ram.
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公开(公告)号:US20200316307A1
公开(公告)日:2020-10-08
申请号:US16908136
申请日:2020-06-22
申请人: Antares Pharma, Inc.
摘要: An injector (10) for injecting a medicament into a patient. The injector includes a container (18) defining a first chamber (22), which contains a fluid therein, and a second chamber (23). The injector also includes an injection conduit (126) configured for directing the fluid fired from the container into the patient. A transfer mechanism is operable by a user to transfer the fluid from the first chamber to the second chamber in a first stage of operation, and a firing mechanism is operable by the user for firing the fluid from the second chamber through the injection conduit in a second stage of operation. An energy source (62) is in powering association with the firing mechanism to drive firing mechanism in the first and second stages.
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