公开(公告)号：US12016879B2

公开(公告)日：2024-06-25

申请号：US16171678

申请日：2018-10-26

申请人： Boston Scientific Scimed, Inc. ,  Mayo Foundation for Medical Education and Research

发明人： Sarah M. Gruba ,  Douglas D. Pagoria ,  James P. Rohl ,  Stephen J. Hahn ,  Suraj Kapa ,  Chance M. Witt

IPC分类号： A61B18/14 ,  A61K9/00 ,  A61K33/06 ,  A61K33/14 ,  A61K33/42 ,  A61B18/00

CPC分类号： A61K33/06 ,  A61B18/1492 ,  A61K9/0009 ,  A61K33/14 ,  A61K33/42 ,  A61B2018/0022 ,  A61B2018/00238 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/00613 ,  A61B2018/00839

摘要： In various aspects, the present disclosure provides methods for applying ablation therapy to a target tissue region within a patient, which methods include: (a) navigating a catheter to a target tissue region within the patient, the catheter including an elongate body having a proximal portion and a distal portion and a balloon structure positioned at the distal portion of the elongate body, which balloon structure may be permeable to a calcium-ion-containing solution that comprises one or more calcium salts; (b) positioning the balloon structure at the target tissue region; (c) delivering energy to the target tissue region; and (d) eluting the calcium-ion-containing solution from the balloon structure before, during, and/or after delivering the energy to the target tissue region. In various other aspects, the present disclosure provides apparatuses that can be used for performing such methods, among others.

公开(公告)号：US12059350B2

公开(公告)日：2024-08-13

申请号：US17015268

申请日：2020-09-09

申请人： Boston Scientific Scimed, Inc.

发明人： Kenny D. Bruner

IPC分类号： A61F2/24

CPC分类号： A61F2/2445 ,  A61F2/2466 ,  A61F2220/0016

摘要： A spring loaded, self-locking anchoring assembly converts a drive force, administered to an anchor of the anchoring assembly, to one or both of an axial translation force or a compression force. The axial translation force may be used to drive the anchor into tissue, while the compression force may be used to further draw together anchor components and tissue, and/or to lock together anchor components, to improve anchor efficacy in the presence of anatomical variations.

公开(公告)号：US20120059455A1

公开(公告)日：2012-03-08

申请号：US13216371

申请日：2011-08-24

申请人： Jan Weber ,  Aiden Flanagan ,  Torsten Scheuermann

发明人： Jan Weber ,  Aiden Flanagan ,  Torsten Scheuermann

IPC分类号： A61L27/54 ,  A61F2/82 ,  C22C23/02

CPC分类号： A61L31/022 ,  A61F2/04 ,  A61F2/07 ,  A61F2/915 ,  A61F2002/91516 ,  A61F2002/91583 ,  A61F2250/0067 ,  A61F2250/0098 ,  A61L31/088 ,  A61L31/146 ,  A61L31/148 ,  A61L31/16 ,  A61L2420/08 ,  C22C23/02

摘要： A bioerodible endoprosthesis includes a bioerodible magnesium alloy. The bioerodible magnesium alloy includes magnesium, between 7 and 8 weight percent aluminum, between 0.4 and 0.8 weight percent zinc, and between 0.05 and 0.8 weight percent manganese.

摘要翻译： 生物腐蚀性内置假体包括生物腐蚀性镁合金。 生物腐蚀性镁合金包括镁，7至8重量％的铝，0.4至0.8重量％的锌和0.05至0.8重量％的锰。

公开(公告)号：US20090276033A1

公开(公告)日：2009-11-05

申请号：US12495155

申请日：2009-06-30

申请人： David W. Mayer

发明人： David W. Mayer

IPC分类号： A61F2/06

CPC分类号： A61F2/90 ,  A61F2220/0008 ,  A61F2220/0016 ,  Y10T428/12333

摘要： A body compatible stent is formed of multiple filaments arranged in at least two sets of oppositely directed helical windings interwoven with one another in a braided configuration. Each of the filaments is a composite including a central core and a case surrounding the core. In the more preferred version, the core is formed of a radiopaque and relatively ductile material, e.g. tantalum or platinum. The outer case is formed of a relatively resilient material, e.g. a cobalt/chromium based alloy. Favorable mechanical characteristics of the stent are determined by the case, while the core enables in vivo imaging of the stent. The composite filaments are formed by a drawn filled tubing process in which the core is inserted into a tubular case of a diameter substantially more than the intended final filament diameter. The composite filament is cold-worked in several steps to reduce its diameter, and annealed between successive cold working steps. After the final cold working step, the composite filament is formed into the desired shape and age hardened. Alternative composite filaments employ an intermediate barrier layer between the case and core, a biocompatible cover layer surrounding the case, and a radiopaque case surrounding a structural core.

摘要翻译： 身体相容的支架由布置在至少两组相互指向的螺旋形绕组中的多根细丝形成，所述螺旋形绕组在编织结构中彼此交织。 每个长丝是包括中心芯和围绕芯的壳体的复合材料。 在更优选的版本中，芯由不透射线的和相对延性的材料形成，例如。 钽或铂。 外壳由相对弹性的材料形成，例如， 钴/铬基合金。 通过这种情况确定支架的有利的机械特性，而核心能够进行支架的体内成像。 复合长丝通过拉伸的填充管道方法形成，其中芯被插入直径基本上大于预期的最终丝直径的管状壳体中。 复合长丝在几个步骤中冷加工以减小其直径，并在连续的冷加工步骤之间退火。 在最后的冷加工步骤之后，将复合长丝形成为期望的形状并且老化硬化。 替代的复合细丝在外壳和芯之间采用中间阻挡层，围绕外壳的生物相容的覆盖层和围绕结构芯的不透射线的外壳。