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公开(公告)号：US12064814B2
公开(公告)日：2024-08-20
申请号：US17266371
申请日：2019-07-09
发明人： Kenjiro Sugio , Takuya Takahashi , Hitoshi Sawada , Gen Sasaki , Kazuhiro Matsugi , Yongbum Choi , Zhefeng Xu , Hajime Suetsugu , Hiroki Kondo , Hideki Manabe , Kyotaro Yamane , Kenichi Hatakeyama , Keizo Kawasaki , Tsuyoshi Itaoka , Shinsaku Seno , Yasushi Tamura , Ichirou Ino , Yoshihide Hirao
摘要： Provided is a method of producing a composite having high strength and high thermal conductivity. The method includes: an alloy preparation step including preparing an alloy which is a solid solution containing α-Fe as a solvent and at least one type of α-phase stabilizing element as a solute; a first mixing step including mixing at least one type of α-phase stabilizing element in powder form and SiC to prepare a first mixture; a second mixing step including mixing the alloy and the first mixture to prepare a second mixture; and a sintering step including sintering the second mixture.
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公开(公告)号：US20240110364A1
公开(公告)日：2024-04-04
申请号：US18262645
申请日：2021-12-21
发明人： Kazushige KOIWAI , Yohei ONO , Natsuki YUMOTO , Shin WAKITANI , Toru YAMAMOTO
IPC分类号： E02F9/22
CPC分类号： E02F9/2235 , E02F9/2296
摘要： A pump control device and a valve control device each includes: an instruction calculator that calculates a control instruction of causing a controlled object to operate by using a manipulation amount of a manipulation and at least one control parameter, and inputs the calculated control instruction to the controlled object; and an ideal output calculator that calculates an ideal output of an actuator, the ideal output being associated with the manipulation amount of the manipulation. The pump control device adjusts at least one pump control parameter to reduce a difference between a control output and the ideal output when an operation of a movable part is a power running operation. The valve control device adjusts at least one valve control parameter to reduce a difference between a control output and the ideal output when the operation of the movable part is a non-power running operation.
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公开(公告)号：US20230399812A1
公开(公告)日：2023-12-14
申请号：US18251319
申请日：2021-10-21
CPC分类号： E02F3/437 , E02F9/265 , E02F9/2029
摘要： An automatic operating device includes: a position estimation part that includes an interaction model, and calculates, as estimative position data, actual position data corresponding to force data which is input; a force computation part that includes a force computation model, calculates force data corresponding to a deviation which is input, and inputs the force data to the position estimation part; a database that stores a base parameter that is a parameter having been calculated in past; and a parameter setting part that calculates, on the basis of the base parameter, a target parameter corresponding to each of a norm y(t) of an actual position and a norm u(t) of a force, and sets the target parameter to a parameter of each of the interaction model and the force computation model.
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公开(公告)号：US11833192B2
公开(公告)日：2023-12-05
申请号：US17494733
申请日：2021-10-05
发明人： Manabu Kuroda , Shotaro Yamaguchi , Norihisa Kato
IPC分类号： C12N9/62 , A61K38/48 , A61P1/14 , A23L33/17 , A61P1/10 , A61K9/00 , A61K38/46 , A23L2/52 , A61K36/062 , C12N9/50 , A23L33/10 , A23L29/00 , A23K50/30 , C12N9/26 , C12N9/24
CPC分类号： A61K38/46 , A23K50/30 , A23L2/52 , A23L29/06 , A23L33/10 , A23L33/17 , A61K9/0053 , A61K36/062 , A61K38/48 , A61K38/4806 , A61P1/10 , A61P1/14 , C12N9/248 , C12N9/2411 , C12N9/50 , C12N9/62 , A01K2227/108 , A23V2002/00 , A23V2002/00 , A23V2200/32 , A23V2250/208
摘要： A method for improving intestinal flora increases the number of beneficial bacteria such as lactic acid bacteria and Bifidobacterium to improve intestinal flora by using an enzyme. The method involves providing a protease, which is a polypeptide having an amino acid sequence shown in SEQ ID NO: 1 that can increase beneficial bacteria such as lactic acid bacteria and Bifidobacterium in intestines to exert an excellent effect of improving intestinal flora.
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公开(公告)号：US11808008B2
公开(公告)日：2023-11-07
申请号：US17425510
申请日：2020-01-14
发明人： Hideki Hayashi , Ryota Nakahara , Michio Hirayama , Kenjiro Kumitani , Taira Iji , Manabu Shimada
CPC分类号： E02F9/0866 , B60K11/04 , F01P1/00 , F01P11/10
摘要： A construction machine is capable of reducing a decrease in work efficiency due to maintenance for capturing dust. The construction machine includes: an engine; a heat exchanger; a cooling fan that sucks air into an engine chamber to pass the air through the heat exchanger; an intake chamber independent of the engine chamber; an intake tube connected to the intake chamber; and a dust receiving part. The intake tube has a curved part, which has an outside inner wall surface allowing dust in the air to contact it. The dust receiving part is located downstream of the outside inner wall surface to be capable of receiving dust.
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公开(公告)号：US20230041186A1
公开(公告)日：2023-02-09
申请号：US17778695
申请日：2020-10-14
发明人： Yukihiro HOSO , Yusuke FUNAHARA , Sho FUJIWARA , Toru TAMAKI
摘要： A measurement device is configured to: calculate first contour data of a container in an empty state at a first time; calculate second contour data indicating a surface contour of an object at a second time in execution of a scooping operation by the container; rotate the second contour data, based on differential information indicating a difference between second posture data of a working gear 4 at the second time and first posture data of the working gear 4 at the first time; specify a region defined by supplemental contour data for supplementing the surface contour of the object contained in the container in the execution of the scooping operation, the rotated second contour data, and the first contour data; and calculate, based on the specified region, a first volume indicating a volume of the object contained in the container.
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公开(公告)号：US20230003002A1
公开(公告)日：2023-01-05
申请号：US17782756
申请日：2020-11-30
发明人： Masaru ITO , Yuichi KURITA
摘要： A remote operation device and a remote operation system that can reduce or eliminate deviation of the position of an indicator image of a working unit such as a line image in an image with respect to the position of the working unit in a real space. In some case, because of a cause such as a communication failure, a position posture coordinate value of a working unit corresponding to captured image data in a work environment image deviates from a position posture coordinate value of the working unit estimated according to an operation form of a remote operation mechanism. In this case, a semitransparent indicator image Img2(τ2) simulating a bucket is superimposed on a work environment image Img1(τ2) in a position where the bucket is estimated to be originally present and deviating from an image region representing the bucket.
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公开(公告)号：US20220313741A1
公开(公告)日：2022-10-06
申请号：US17844882
申请日：2022-06-21
发明人： Naosuke KAMEI , Mari DEZAWA , Mitsuo OCHI
IPC分类号： A61K35/28 , C12N5/077 , C12N5/0775
摘要： A method for treating or repairing osteochondral damage in a subject in need thereof, including administering to the subject a cell preparation comprising pluripotent stem cells positive for SSEA-3 isolated from a body mesenchymal tissue or cultured mesenchymal cells. The pluripotent stem cells have all of the following properties: (i) CD105-positivity; (ii) low or absent telomerase activity; (iii) having ability to differentiate into any of three germ layers; (iv) absence of demonstration of neoplastic proliferation; and (v) self-renewal ability. The pluripotent stem cells are administered at 1×103 cells to 2×107 cells as individual.
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公开(公告)号：US20220098823A1
公开(公告)日：2022-03-31
申请号：US17425510
申请日：2020-01-14
发明人： Hideki HAYASHI , Ryota NAKAHARA , Michio HIRAYAMA , Kenjiro KUMITANI , Taira IJI , Manabu SHIMADA
摘要： A construction machine is capable of reducing a decrease in work efficiency due to maintenance for capturing dust. The construction machine includes: an engine; a heat exchanger; a cooling fan that sucks air into an engine chamber to pass the air through the heat exchanger; an intake chamber independent of the engine chamber; an intake tube connected to the intake chamber; and a dust receiving part. The intake tube has a curved part, which has an outside inner wall surface allowing dust in the air to contact it. The dust receiving part is located downstream of the outside inner wall surface to be capable of receiving dust.
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公开(公告)号：US20220031757A1
公开(公告)日：2022-02-03
申请号：US17503756
申请日：2021-10-18
发明人： Yukio Kato , Koichiro Tsuji , Ayumu Nakashima , Takao Masaki , Shigehiro Doi , Ken Yoshida
摘要： In order to provide (i) a repair agent for damaged tissue and (ii) a method for producing the repair agent, the present invention uses mesenchymal stem cells cultured in a serum-free medium.
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