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公开(公告)号：US20050228485A1
公开(公告)日：2005-10-13
申请号：US11136002
申请日：2005-05-24
申请人： Giovanni Rolando , Paolo Gaschino
发明人： Giovanni Rolando , Paolo Gaschino
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91516 , A61F2002/91533 , A61F2002/9155 , A61F2002/91566
摘要： An angioplasty stent comprises a body comprising a plurality of successive segments connected in pairs by bridge means so that the successive segments can be oriented relative to one another for the purposes of bending of the body in any direction defined by a linear combination of respective orientation axes defined by the bridge connection means. During the radial expansion of the stent, the axial contraction of the segments resulting from the opening-out of the respective loops is compensated by axial projection of the bridge elements from the respective concave portions. The wall of the body comprises arms for supporting a lumen as well as regions which are selectively deformable during the expansion of the stent, the arms and the selectively deformable regions having different cross-sections and/or cross-sectional areas. At least one portion of the body may have a substantially reticular structure, the branches of which define geometrical figures identifiable as fractals.
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公开(公告)号：US20040172124A1
公开(公告)日：2004-09-02
申请号：US10790649
申请日：2004-03-01
发明人： Franco Vallana , Giovanni Rolando , Maria Curcio , Paolo Gaschino
IPC分类号： A61F002/06
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91541 , A61F2002/9155 , A61F2002/91583 , A61F2230/0054 , A61F2250/0068
摘要： A stent for use at an implant site in a vessel having recesses containing one or more active agents. The stent is a tubular body having a plurality of sinusoidal shaped annular elements and connection elements. The recesses are formed so as to leave substantially unaltered the bending moments of these elements. The recesses may be continuous or discontinuous and may be distributed uniformly or nonuniformly.
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公开(公告)号：US20030195613A1
公开(公告)日：2003-10-16
申请号：US10431557
申请日：2003-05-07
发明人： Maria Curcio , Giovanni Rolando , Franco Vallana
IPC分类号： A61F002/06
CPC分类号： A61F2/82 , A61F2/0077 , A61F2/86 , A61F2250/0025 , A61F2250/0068 , A61F2310/00574 , A61F2310/0058 , A61L31/022 , A61L31/084 , A61L31/14 , A61L31/16 , A61L33/025 , A61L2300/416 , A61L2300/42 , A61L2400/18 , Y10T29/49885 , Y10T29/49995
摘要： A stent has surface sculpturing, preferably on its outer surface only, having, for example, microspheres, having the function of increasing the actual geometric surface area of the stent, of creating undercuts and roughness to encourage the application of coatings of active or activatable agents, as well as of improving the attachment of the stent to the blood vessel wall.
摘要翻译： 支架具有表面雕刻，优选仅在其外表面上具有例如具有增加支架的实际几何表面积的功能的微球，产生底切和粗糙度以促进施加活性或可激活剂的涂层 ，以及改善支架到血管壁的附着。
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公开(公告)号：US5873812A
公开(公告)日：1999-02-23
申请号：US818783
申请日：1997-03-11
CPC分类号： A61L27/3687 , Y10S623/918
摘要： A method of preparing biological implantation material fixed by means of aldehydes, in which the excess aldehyde is bound by treatment with an aminocarboxylic acid and the acid is selected from compounds of the general formula: ##STR1## in which n is 1 or 2 and X is a sulpho- (--SO.sub.3 H) or phosphono- (--PO.sub.3 H) group, and mixtures of such compounds.
摘要翻译： 制备通过醛固定的生物植入材料的方法，其中过量的醛通过用氨基羧酸和酸处理而结合，该酸选自下列通式的化合物：（ⅠB） 其中n为1或2，X为磺基 - （ - SO 3 H）或膦 - （ - PO 3 H）基团，以及这些化合物的混合物。
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公开(公告)号：US5762870A
公开(公告)日：1998-06-09
申请号：US831960
申请日：1997-04-02
申请人： Franco Vallana , Stefano Rinaldi , Giampiero Porro , Massimo Fini
发明人： Franco Vallana , Stefano Rinaldi , Giampiero Porro , Massimo Fini
CPC分类号： B01D65/08 , B01D63/027 , B01D63/06 , F28F13/06 , F28F21/062 , A61M1/1698 , B01D2321/2016
摘要： The structure has a core which may be a strand or braid, as well as a sheath surrounding the core and defining the exchange surface. Preferred applications are for biomedical equipment such as blood oxygenators and blood purification equipment.
摘要翻译： 该结构具有可以是线或编织物的芯，以及围绕芯并且限定交换表面的护套。 优选的应用是用于生物医学设备，例如血液氧合器和血液净化设备。
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公开(公告)号：US07220277B2
公开(公告)日：2007-05-22
申请号：US10393448
申请日：2003-03-20
IPC分类号： A61F2/24
CPC分类号： A61F2/2448 , A61F2250/0018
摘要： A prosthesis for annuloplasty comprising a laminar or tubular element having a plurality of apertures along at least one portion. Preferably, the shape, dimensions, and arrangements of the apertures in this prosthesis are chosen in such a way as to give the prosthesis a differentiated flexibility in dependence on the location and direction of application of an external stress.
摘要翻译： 用于瓣膜成形术的假体包括沿着至少一个部分具有多个孔的层状或管状元件。 优选地，这种假体中的孔的形状，尺寸和布置以这样的方式选择，以便根据施加外部应力的位置和方向给予假体差异的灵活性。
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7.发明授权Process for coupling an angioplasty stent to a corresponding insertion element, and kit thus formed 有权用于将血管成形术支架联接到相应的插入元件的方法和由此形成的试剂盒公开(公告)号：US06878158B2
公开(公告)日：2005-04-12
申请号：US09852988
申请日：2001-05-10
申请人： Dong Shin , Vincenzo Cassolaro , Andrea Mariotto
发明人： Dong Shin , Vincenzo Cassolaro , Andrea Mariotto
CPC分类号： A61F2/958 , A61F2002/9522
摘要： A process for setting an angioplasty stent on a corresponding insertion element, such as a delivery catheter, in which the angioplasty stent is subjected to an action of radial contraction. The stent is in a radially contracted state before being placed on the insertion element. Preferably, radial contraction of the stent results in a diameter at least marginally smaller than the diameter of the insertion element, e.g., a balloon catheter. After the stent has been set on the insertion element, in the structure of the stent there remain residual states of constraint which act in the direction of securing the stent in the condition of coupling to the insertion element.
摘要翻译： 将血管成形术支架设置在相应的插入元件（例如输送导管）上的方法，其中血管成形术支架经受径向收缩的作用。 在放置在插入元件之前，支架处于放射状收缩状态。 优选地，支架的径向收缩导致直径至少小于插入元件（例如球囊导管）的直径。 在支架已经设置在插入元件上之后，在支架的结构中，保持残留的约束状态，其在固定支架的方向上与连接到插入元件的状态起作用。
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公开(公告)号：US20020183831A1
公开(公告)日：2002-12-05
申请号：US10159969
申请日：2002-05-31
发明人： Giovanni Rolando , Paolo Gaschino
IPC分类号： A61F002/06
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91541 , A61F2002/9155 , A61F2002/91583 , A61F2230/0054 , A61F2250/0036
摘要： This invention is a stent having a substantially tubular body defining a longitudinal axis comprising first and second adjacent annular segments, each segment defining a substantially sinusoidal shape having a plurality of peaks and valleys, the peaks of the first segment extending toward the second segment and being aligned longitudinally with the valleys of the second segment. The stent has a plurality of bridge elements having a U-shaped portion between first and second connector arms, the first connector arm of one bridge element being connected between a first peak and a first valley of the first segment and the second connector arm being connected between a first peak and a first valley of the second segment.
摘要翻译： 本发明是一种支架，其具有限定纵向轴线的基本上管状的主体，该纵向轴线包括第一和第二相邻的环形段，每个段限定具有多个峰和谷的基本正弦形状，第一段的峰向第二段延伸， 与第二段的谷部纵向对齐。 支架具有在第一和第二连接器臂之间具有U形部分的多个桥接元件，一个桥接元件的第一连接臂连接在第一段的第一峰与第一谷之间，第二连接臂连接 在第二段的第一峰和第一谷之间。
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公开(公告)号：US20020117264A1
公开(公告)日：2002-08-29
申请号：US10135639
申请日：2002-04-30
IPC分类号： A61L002/00
CPC分类号： A61L27/00 , A61F2/0077 , A61F2/0095 , A61F2/02 , A61F2/06 , A61F2/2409 , A61L33/0005 , Y10T156/1744
摘要： A prosthesis having an apertured structure is located in a chamber (11) which is taken to sub-atmospheric pressure. Once sub-atmospheric pressure has been reached, a liquid, optionally containing pharmacological agents, is introduced into the chamber. Drawn by the sub-atmospheric pressure, the liquid saturates the apertured structure of the prosthesis. In this way, the invention eliminates the risk of air being trapped in the apertured structure that could give rise to the formation of blood clots after implantation of the prosthesis. The liquid can contain drugs that penetrate the prosthesis, performing their therapeutic action locally and over time after implantation.
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公开(公告)号：US20010049541A1
公开(公告)日：2001-12-06
申请号：US09299862
申请日：1999-04-26
IPC分类号： A61N001/362
CPC分类号： A61N1/3622 , A61N1/3962
摘要： An implantable heart-stimulation apparatus having a plurality of stimulation electrodes which can be applied to the heart muscle in one or more chambers of the heart in order to apply electrical stimulation signals thereto, and stimulation-control means for applying stimulation signals to the electrodes in accordance with a time plan determined individually and separately for each of the plurality of electrodes. The preferred application is for the correction of myocardial electrical conduction defects, for example, in atrial fibrillation and cardiac insufficiency.
摘要翻译： 一种植入式心脏刺激装置，其具有多个刺激电极，其能够施加到心脏的一个或多个腔室中的心脏肌肉以便向其施加电刺激信号，以及刺激控制装置，用于向电极施加刺激信号 根据对于多个电极中的每一个分别确定的时间表。 优选的应用是用于校正心肌电传导缺陷，例如心房颤动和心脏功能不全。
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