PEPTIDE FRAGMENT AND USE THEREOF
    3.
    发明公开

    公开(公告)号:US20240262863A1

    公开(公告)日:2024-08-08

    申请号:US18557620

    申请日:2022-03-25

    IPC分类号: C07K7/08 C12N15/87

    CPC分类号: C07K7/08 C12N15/87

    摘要: The present disclosure provides an artificially synthesized peptide fragment capable of efficiently introducing a target foreign substance from outside a eukaryotic cell into at least the cytoplasm of the cell. A peptide fragment disclosed herein is for introducing a target foreign substance from outside a eukaryotic cell into at least the cytoplasm of the cell, the peptide fragment being configured such that two or more of amino acid sequences VVKSLVK (SEQ ID NO: 1) are arranged in series, and another amino acid residue is not included between the amino acid sequences or a peptide linker composed of 1 to 5 amino acid residues is interposed between the amino acid sequences.

    Water repellent and oil repellent film composition and use thereof

    公开(公告)号:US11981828B2

    公开(公告)日:2024-05-14

    申请号:US16972264

    申请日:2019-06-04

    申请人: TOAGOSEI CO. LTD.

    摘要: The present teaching provides a water repellant and oil repellant film composition comprising a siloxane compound represented by formula (1) or a cured product of the siloxane compound.




    (In formula (1), each R1 denotes at least one atom or group that is selected from the group consisting of a hydrogen atom, organic groups having 2 to 10 carbon atoms and a carbon-carbon unsaturated bond that is able to be hydrosilylated, and alkyl groups having 1 to 10 carbon atoms, each R2 denotes at least one atom or group that is selected from the group consisting of a hydrogen atom, organic groups having 2 to 10 carbon atoms and a carbon-carbon unsaturated bond that is able to be hydrosilylated, and alkyl groups having 1 to 10 carbon atoms (the R2 groups in a single molecule may be the same as, or different from, each other). Each R3 denotes at least one atom or group that is selected from the group consisting of a hydrogen atom, organic groups having 2 to 10 carbon atoms and a carbon-carbon unsaturated bond that is able to be hydrosilylated, and alkyl groups having 1 to 10 carbon atoms (the R3 groups in a single molecule may be the same as, or different from, each other), each R4 denotes an alkyl group having 1 to 6 carbon atoms, and at least some of the R2 groups or at least some of the R3 groups are hydrogen atoms and organic groups having 2 to 10 carbon atoms and a carbon-carbon unsaturated bond that is able to be hydrosilylated. w and x each denote a positive number, v, y and z each denote 0 or a positive number, and the value of x/(v+w+x+y) is 0.2 or more.)

    SECONDARY BATTERY ELECTRODE BINDER, SECONDARY BATTERY ELECTRODE MIXTURE LAYER COMPOSITION, SECONDARY BATTERY ELECTRODE AND SECONDARY BATTERY

    公开(公告)号:US20240105948A1

    公开(公告)日:2024-03-28

    申请号:US17767988

    申请日:2020-10-02

    IPC分类号: H01M4/62 H01M4/04 H01M10/052

    摘要: The present invention provides a secondary battery electrode binder that exhibits superior binding capacity as compared to conventional binders and that also makes it possible to reduce electrode slurry viscosity, even when there is a high concentration of active material in an electrode mixture layer composition. The present invention also provides a secondary battery electrode mixture layer composition, a secondary battery electrode, and a secondary battery that are obtained using the binder. The present invention relates to a secondary battery electrode binder that contains a carboxyl-group-containing polymer or a salt of a carboxyl-group-containing polymer. The carboxyl-group-containing polymer or salt of a carboxyl-group-containing polymer includes structural units that are derived from monomers that are represented by general formula (1) and structural units that are derived from ethylenic unsaturated carboxylic acid monomers that are different from general formula (1). The structural units derived from monomers that are represented by general formula (1) are 0.1-20 mass % of the total structural units of the carboxyl-group-containing polymer or salt of a carboxyl-group-containing polymer.

    Carrier peptide fragment and use thereof

    公开(公告)号:US11814448B2

    公开(公告)日:2023-11-14

    申请号:US17525097

    申请日:2021-11-12

    IPC分类号: C07K7/08 C07K14/00 C12N5/09

    摘要: The present disclosure provides an artificially synthesized peptide fragment that can efficiently introduce a foreign substance of interest from outside a eukaryotic cell into at least the cytoplasm of the cell. The present disclosure also provides a method for using the peptide fragment. The herein disclosed peptide fragment is a peptide fragment for introducing a foreign substance of interest from outside a eukaryotic cell into at least the cytoplasm of the cell, and is provided with a repeat sequence in which the VVRSLVK amino acid sequence (SEQ ID NO: 1) is repeated at least two or more times. By using a construct that has the peptide fragment and the foreign substance of interest bonded to the N-terminal side and/or C-terminal side of the peptide fragment, the foreign substance of interest can be efficiently introduced from outside a eukaryotic cell into at least the cytoplasm of the cell.