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公开(公告)号：US20240319052A1
公开(公告)日：2024-09-26
申请号：US18579780
申请日：2022-07-20
发明人： Hideji TAJIMA
CPC分类号： G01N1/34 , B03C1/01 , B03C1/288 , B03C1/30 , B03C2201/18
摘要： An extracting device 200 includes a plurality of extraction vessels 210 which retain a solution containing magnetic particles and a sample, an oscillating mechanism 220 which oscillates the extraction vessels 210, magnet bodies which exert a magnetic force on extraction vessels 210, a magnet moving mechanism 258, 259 which moves the magnet bodies between a contact position in which the magnet bodies are in contact with the extraction vessels 210 and a non-contact position, a temperature adjustment unit which adjusts a temperature of the extraction vessels 210, a temperature adjustment unit moving mechanism 248, 249 which moves the temperature adjustment unit between a contact position in which the temperature adjustment unit is in contact with the extraction vessels 210 and a non-contact position in which the temperature adjustment unit is not in contact with the extraction vessels 210, and a control unit which controls an action of each of the mechanisms.
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公开(公告)号：US20240254471A1
公开(公告)日：2024-08-01
申请号：US18561218
申请日：2022-05-27
发明人： Hideji TAJIMA
CPC分类号： C12N15/1003 , G01N35/1081
摘要： A specimen processing apparatus 1000 comprising: a plurality of container holders 510 holding, in one row, a plurality of second nucleic acid containers housing the nucleic acids; a pitch conversion mechanism 500 converting a pitch of the plurality of container holders between a smaller pitch and a larger pitch; a plurality of treatment lanes extracting the plurality of nucleic acid from a plurality of specimens in parallel; a first nozzle unit 200 including a plurality of first nozzles 210 disposed in one row at the greater pitch and moving over the plurality of treatment lanes; a PCR plate 128 having a plurality of wells disposed in one row at the smaller pitch; a second nozzle unit 300 including a plurality of second nozzles 310 disposed in one row at the smaller pitch and moving between a location above the plurality of container holders having the smaller pitch and a location above the PCR plate 128; and a control unit controlling operation of respective parts.
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公开(公告)号：US20240241146A1
公开(公告)日：2024-07-18
申请号：US18556723
申请日：2022-03-18
发明人： Hideji TAJIMA
IPC分类号： G01N35/10
CPC分类号： G01N35/1065 , G01N35/1002 , G01N2035/1027
摘要： A dispensing device 400 includes a plurality of dispensing nozzles arranged at predetermined intervals in x and y directions, a dispensing body 430 configured to support the plurality of dispensing nozzles, a mounting body 144 configured to allow a plurality of dispensing tips 142 to be mounted on the mounting body 144 at the predetermined intervals in the x and y directions, an attaching mechanism 432, 144b configured to attach the mounting body 144, on which the plurality of dispensing tips 142 are mounted, to the plurality of dispensing nozzles to install the plurality of dispensing tips 142 on the plurality of dispensing nozzles, a removing mechanism configured to remove the plurality of dispensing tips and the mounting body 144 from the plurality of dispensing nozzles, and a control unit configured to control operations of the plurality of dispensing nozzles, the attaching mechanism, and the removing mechanism.
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公开(公告)号：US11313871B2
公开(公告)日：2022-04-26
申请号：US16497843
申请日：2018-03-28
发明人： Hideji Tajima
摘要： The specimen treatment and measurement system 2000 according to the present invention is provided with: a movement stage 2300 having a plurality of treatment lanes for treating specimens in parallel; a consumables supply module 2100 for storing consumables for use in treatment of the specimens, and supplying the consumables to the movement stage 2300; a cartridge supply module 2500 for storing cartridges for use in treatment of the specimens, and supplying the cartridges to the movement stage 2300; and a stage transfer mechanism 2400 for transferring the movement stage 2400 to each module. The cartridge supply module 2500 has a plurality of cartridge cartons for accommodating the cartridges stacked on top of each other, and a push-out mechanism for pushing cartridges out of a cartridge carton to a supply position of the cartridge supply module 2500.
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公开(公告)号：US11099132B2
公开(公告)日：2021-08-24
申请号：US16189663
申请日：2018-11-13
发明人： Hideji Tajima
IPC分类号： G01N21/64 , G01N35/04 , G01N35/02 , G02B21/00 , G01N21/25 , C12Q1/686 , G01N21/27 , G01N21/11 , G01N35/10
摘要： The invention relates to an optical measurement device for a reaction vessel, and a method therefor. An object is to measure the optical state within a reaction vessel in an efficient, rapid, and highly reliable manner, without an expansion of the device scale. The configuration includes: a vessel group in which two or more reaction vessels are arranged; a light guide stage having two or more linking portions to which front ends of light guide portions, which have a flexibility, that optically connect with the interior of the linked reaction vessels, are provided; a connecting end arranging body that has an arranging surface that arranges and supports along a predetermined path two or more connecting ends, to which back ends of the light guide portions, in which the front ends thereof are provided to the linking portions, are provided, the connecting ends are provided corresponding to the respective linking portions; a measurement device provided approaching or making contact with the arranging surface that has measuring ends that are successively optically connectable with the respective connecting ends along the predetermined path, and in which light from within the reaction vessels is receivable by means of optical connections between the connecting ends and the measuring ends; and a light guide switching mechanism that relatively moves the respective connecting ends arranged on the connecting end arranging body and the respective measuring ends such that they are successively optically connected.
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公开(公告)号：US10976253B2
公开(公告)日：2021-04-13
申请号：US16060556
申请日：2016-12-14
发明人： Hideji Tajima , Takaki Sugimoto , Tetsuya Ueda
摘要： A highly-reliable absorbance measuring device that enables highly-accurate measurement of absorbance, and a method thereof are provided.
A liquid containing unit that can contain a chemical substance solution to be measured, a nozzle that communicates with a suction/discharge mechanism that sucks/discharges gas, a flow tube that includes a mouth part, which can be inserted into the liquid containing unit, at a lower end and that is detachably attached to the nozzle at an upper end, an emitting end that can emit measurement light, a light receiving end that can receive the light emitted from the emitting end, and a control unit are included. The control unit is configured to suck a prescribed amount of the chemical substance solution into the flow tube, and to lead absorbance on the basis of intensity of transmitted light acquired by emission of measurement light in a vertical direction into the flow tube.-
公开(公告)号：US10822646B2
公开(公告)日：2020-11-03
申请号：US15263483
申请日：2016-09-13
发明人： Hideji Tajima
IPC分类号： C12Q1/68 , G01N21/13 , C12Q1/686 , G01N35/10 , G01N21/64 , G01N35/00 , G01N21/31 , C12Q1/6848 , B01L7/00
摘要： A reaction container control system including a reaction container, a sealing lid, a temperature control block, and a heater. The reaction container includes a lower side wall section, an upper side wall section, and an aperture. The sealing lid seals the reaction container by fitting to the aperture of the reaction container. When the sealing lid is fitted to the aperture, light based on an optical state within the reaction container is receivable by a measuring device via the sealing lid. The temperature control block contacts or extends adjacent the lower side wall section, and includes a temperature source operable to increase or decrease a temperature inside the reaction container. The heater contacts or extends adjacent the upper side wall section, and includes a heat source operable to heat the reaction container to prevent condensation on the sealing lid fitted to the aperture.
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公开(公告)号：US20200209268A1
公开(公告)日：2020-07-02
申请号：US16303121
申请日：2017-05-25
发明人： Hideji TAJIMA
IPC分类号： G01N35/02 , G01N35/00 , G01N35/10 , C12N15/10 , C12Q1/6844
摘要： A specimen treating and measuring system according to the present invention comprises: a treatment part having a plurality of lanes for carrying out parallel processing of a plurality of specimens, and mounting cartridges in each of the plurality of lanes; a cartridge storing unit storing a plurality of types of cartridge to be used for different processes corresponding to the plurality of specimens; a sample storing unit storing and conveying sample tubes containing the plurality of specimens; a pickup unit transferring each of the plurality of types of cartridge to each lane, and transferring each of the plurality of specimens from the sample tubes to each of the plurality of lanes; and a control unit controlling the transfer of the plurality of types of cartridge and the transfer of the plurality of specimens, performed by the pickup unit.
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公开(公告)号：US10288606B2
公开(公告)日：2019-05-14
申请号：US14437450
申请日：2013-10-21
IPC分类号： G01N33/00 , G01N33/543 , G01N21/64 , G01N21/76 , G01N21/77
摘要： The present invention provides an analysis method for simultaneously detecting or quantifying plural species of target substances by measuring the light emission from plural carriers within a single container from outside of the container, these carriers comprising a plurality of substances that are respectively immobilized thereon for capturing the plural species of target substances, wherein the light emission from a desired carrier is selectively received by measuring the emission from the carriers through an optical filter. The present invention also provides an analysis kit for simultaneously detecting or quantifying plural species of target substances by measuring the light emission from plural carriers within a single container from outside of the container, these carriers comprising a plurality of substances that are respectively immobilized thereon for capturing the plural species of target substances, which comprises the plural carriers and an optical filter for selectively receiving the emission from a desired carrier.
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公开(公告)号：US20170081656A1
公开(公告)日：2017-03-23
申请号：US15123582
申请日：2015-03-18
发明人： Ryouji KARINAGA , Tetsuya UEDA , Hideji TAJIMA
IPC分类号： C12N15/10
CPC分类号： C12N15/1013 , C12N15/1006
摘要： In a method of nucleic acid extraction using a carrier, the present invention realizes collection of a nucleic acid from a liquid containing the nucleic acid at an extremely low concentration at which collection cannot be achieved with polyacrylamide.A method of extracting a nucleic acid, comprising allowing the nucleic acid to be adsorbed onto a carrier in the presence of a chaotropic salt and an alcohol in coexistence with an anionic polymer. A reagent for nucleic acid extraction, comprising an anionic polymer, a chaotropic salt, an alcohol and a carrier.
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