公开(公告)号：US20030195104A1

公开(公告)日：2003-10-16

申请号：US10413890

申请日：2003-04-14

申请人： Gambro, Inc.

发明人： Dennis J. Hlavinka ,  William G. Palsulich ,  Thomas J. Felt ,  Frank Corbin III

IPC分类号： B04B005/02 ,  B04B011/00

CPC分类号： A61M1/0209 ,  A61M1/3693 ,  B04B5/0428

摘要： A centrifugal fluid separation system is disclosed for centrifugally separating a composite fluid into components thereof. This centrifugal separation system includes at least a centrifugal rotor which has a composite fluid containment area, a fluid flow channel/tubing and at least one separated component collection area defined therein. A composite fluid to be separated is delivered to the fluid containment area where under centrifugal forces the composite fluid is separated into components and then from which a component travels through an outlet channel to a respective separated component fluids flowing therethrough. A centrally disposed pump is also provided to move the separated component(s) to the collection area(s). Optical sensing of the interface of the separated fluid components may be used with a clamp to stop flow. A disposable bag and tubing system is also disclosed for use with reusable rotor devices.

公开(公告)号：US20020151423A1

公开(公告)日：2002-10-17

申请号：US10174188

申请日：2002-06-18

发明人： Glen E. Jorgensen ,  Bruce Berckmans III

IPC分类号： B04B005/02

CPC分类号： A61M1/3693 ,  A61M1/0209 ,  A61M1/029 ,  A61M1/3698 ,  A61M2202/0427 ,  B04B5/0428 ,  B04B2005/0435 ,  Y10S383/904

摘要： A single use system and kit for producing blood platelet concentrates is described herein. In a preferred form, the kit includes a bag set in which compartments containing blood components are adjacent to separate compartments which can be inflated to express the blood components after their separation by centrifuging.

摘要翻译： 本文描述了用于生产血小板浓缩物的单次使用系统和试剂盒。 在优选形式中，试剂盒包括袋组，其中含有血液成分的隔室与独立的隔间相邻，隔室可以在通过离心分离后被充气以表达血液成分。

公开(公告)号：US20040209755A1

公开(公告)日：2004-10-21

申请号：US10413881

申请日：2003-04-15

发明人： Patrick Q. Moore ,  Christopher L. Stewart ,  TenLin S. Tsai

IPC分类号： B04B005/02

CPC分类号： B04B5/0414 ,  B04B2005/0435 ,  C12M23/08 ,  C12M33/10

摘要： An adapter for use with a centrifuge. Features of the adapter allow for less friction during extraction of the adapter and separation efficiency by preventing disturbances to the separated materials. In addition, the adapter includes features that support the walls of a sample container and prevent force from damaging the sample container during a centrifuge separation procedure.

摘要翻译： 用于离心机的适配器。 适配器的特征允许通过防止对分离的材料的干扰来提取适配器中的较小摩擦力和分离效率。 此外，适配器包括支撑样品容器的壁的特征，并且在离心分离程序期间防止力损坏样品容器。

公开(公告)号：US20030040418A1

公开(公告)日：2003-02-27

申请号：US10271138

申请日：2002-10-15

申请人： Gentra Systems, Inc.

发明人： Glenn M. Campbell JR. ,  Douglas J. Kluge ,  Glenn M. Campbell SR. ,  Ellen M. Heath ,  Ruth Shuman

IPC分类号： B04B005/02 ,  B04B007/00

CPC分类号： B04B7/02 ,  B04B5/0421 ,  B04B7/00 ,  B04B2007/005

摘要： A rotor locator and centrifuge body locator includes a pair of locator arms that close about the rotor shaft and an alignment pin to center the rotor shaft. A registration mechanism rotates the rotor shaft and the centrifuge body until it reaches a known home position. A method of consistently registering the centrifuge body includes centering a rotor shaft of the body along a known center line and aligning the body to a home position both before and after centrifugation.

公开(公告)号：US20020042336A1

公开(公告)日：2002-04-11

申请号：US10014375

申请日：2001-10-26

发明人： Glen E. Jorgensen ,  Bruce Berckmans III

IPC分类号： B04B005/02

CPC分类号： A61M1/3693 ,  A61M1/0209 ,  A61M1/029 ,  A61M1/3698 ,  A61M2202/0427 ,  B04B5/0428 ,  B04B2005/0435 ,  Y10S383/904

摘要： A single use system and kit for producing blood platelet concentrates is described herein. In a preferred form, the kit includes a bag set in which compartments containing blood components are adjacent to separate compartments which can be inflated to express the blood components after their separation by centrifuging.

摘要翻译： 本文描述了用于生产血小板浓缩物的单次使用系统和试剂盒。 在优选形式中，试剂盒包括袋组，其中含有血液成分的隔室与独立的隔间相邻，隔室可以在通过离心分离后被充气以表达血液成分。

公开(公告)号：US20020032111A1

公开(公告)日：2002-03-14

申请号：US09828296

申请日：2001-04-06

发明人： Paul J. Cornay ,  Ernest Peter Tovani ,  Gary Matzen

IPC分类号： B04B005/02 ,  B04B011/00 ,  B01J008/10

CPC分类号： B04B11/02 ,  A61K31/662 ,  B01J3/008 ,  B01J19/1806 ,  B01J19/20 ,  B01J2219/00078 ,  B01J2219/0009 ,  B01J2219/00132 ,  B01J2219/00135 ,  B01J2219/00155 ,  B01J2219/00159 ,  B01J2219/00162 ,  B04B1/00 ,  B04B1/04 ,  B04B7/08 ,  B04B15/02 ,  C02F1/38 ,  C02F1/72 ,  C02F11/086

摘要： A two-tube centrifuge separates light material and heavy material from an input mixture. A hollow drive shaft rotates a central body member about an axis of rotation. Two hollow arm assemblies, each having circular cross-section, are mounted on diametrically opposite sides of the central body. Each arm assembly includes an outer housing tube, an intermediate tube, and an inner tube that is longer than the intermediate tube. An end cap having a removable plug is mounted on the outer end of the housing-tube of each arm assembly. The inner ends of all three tubes are mechanically interlocked in a manner to cantilever mount the inner and intermediate tubes to the central-body with their outer ends spaced from the internal surface of the end cap. An input-mixture path extends through the hollow drive shaft, through the central-body, and into a cylindrical space between the inner and intermediate tubes of each arm assembly. A heavy material exit path extends from the inner tube, through the central body, and into an exit cone that lies diametrically opposite the drive shaft and whose axis is coincident with the axis of rotation. A light material exit path extends from a cylindrical space between the inner and intermediate tubes, through the central-body, and through a wall of the exit cone. The inner tube of each arm assembly includes an auger. An electric motor drives the drive shaft. A hydraulic motor drives the auger. An oxidation reactor in a centrifuge for decanting lighter material from heavier material from a mixture of initial material and to perform an oxidation reaction process on the heavier material.

摘要翻译： 双管离心机从输入混合物中分离出轻质材料和重质材料。 中空驱动轴围绕旋转轴线旋转中心体部件。 两个具有圆形横截面的中空臂组件安装在中心体的直径相对的两侧。 每个臂组件包括外壳体管，中间管和比中间管长的内管。 具有可拆卸插头的端盖安装在每个臂组件的壳体管的外端上。 所有三个管的内端机械地互锁，以悬臂将内管和中间管安装到中心体，其外端与端盖的内表面间隔开。 输入混合路径穿过中空驱动轴穿过中心体，并且延伸到每个臂组件的内管和中间管之间的圆柱形空间中。 重材料出口路径从内管延伸穿过中心体并且延伸到与驱动轴直径相对并且其轴线与旋转轴线重合的出口锥体。 轻材料出口路径从内管和中间管之间的圆柱形空间延伸穿过中心体，并穿过出口锥体的壁。 每个臂组件的内管包括螺旋钻。 电动机驱动驱动轴。 液压马达驱动螺旋钻。 在离心机中的氧化反应器，用于从较重的材料从初始材料的混合物中倾倒较轻的材料，并在较重的材料上进行氧化反应过程。

公开(公告)号：US20040147386A1

公开(公告)日：2004-07-29

申请号：US10352869

申请日：2003-01-29

发明人： Manfred Grumberg ,  Oren Zinder

IPC分类号： B04B005/02

CPC分类号： B04B7/08 ,  B01L3/502 ,  B01L3/5021 ,  B01L2200/026 ,  B01L2300/042 ,  B01L2300/0672 ,  B01L2400/0409 ,  B04B5/0414 ,  G01N33/491 ,  G01N2035/00495

摘要： A system for separating fluids by centrifuging, the system including: a rotor assembly for rotating in a centrifugation device, the rotor assembly including: (a) a first rotor for housing a plurality of tubes, each of the tubes containing a sample for separation by centrifuging; (b) a second rotor having a plurality of collection compartments, each compartment corresponding to a particular tube, and (c) a plurality of conduits, each corresponding to a particular compartment, each conduit for providing fluid communication, upon demand, between a particular tube and a particular compartment, so as to enable transfer of a fraction of each sample from the tubes to the compartments.

摘要翻译： 一种用于通过离心分离流体的系统，所述系统包括：用于在离心装置中旋转的转子组件，所述转子组件包括：（a）用于容纳多个管的第一转子，每个管包含用于分离的样品， 离心; （b）具有多个收集室的第二转子，每个隔室对应于特定的管，和（c）多个导管，每个导管对应于特定隔室，每个导管用于根据需要提供流体连通， 管和特定隔室，以便能够将每个样品的一部分从管转移到隔室。

公开(公告)号：US20040142807A1

公开(公告)日：2004-07-22

申请号：US10723366

申请日：2003-11-26

发明人： Paul J. Cornay ,  Ernest Peter Tovani ,  Gary Matzen

IPC分类号： B04B005/02 ,  B04B011/00 ,  B01J008/10

CPC分类号： B04B11/02 ,  A61K31/662 ,  B01J3/008 ,  B01J19/1806 ,  B01J19/20 ,  B01J2219/00078 ,  B01J2219/0009 ,  B01J2219/00132 ,  B01J2219/00135 ,  B01J2219/00155 ,  B01J2219/00159 ,  B01J2219/00162 ,  B04B1/00 ,  B04B1/04 ,  B04B7/08 ,  B04B15/02 ,  C02F1/38 ,  C02F1/72 ,  C02F11/086

摘要： A two-tube centrifuge separates light material and heavy material from an input mixture. A hollow drive shaft rotates a central body member about an axis of rotation. Two hollow arm assemblies, each having circular cross-section, are mounted on diametrically opposite sides of the central body. Each arm assembly includes an outer housing tube, an intermediate tube, and an inner tube that is longer than the intermediate tube. An end cap having a removable plug is mounted on the outer end of the housing-tube of each arm assembly. The inner ends of all three tubes are mechanically interlocked in a manner to cantilever mount the inner and intermediate tubes to the central-body with their outer ends spaced from the internal surface of the end cap. An input-mixture path extends through the hollow drive shaft, through the central-body, and into a cylindrical space between the inner and intermediate tubes of each arm assembly. A heavy material exit path extends from the inner tube, through the central body, and into an exit cone that lies diametrically opposite the drive shaft and whose axis is coincident with the axis of rotation. A light material exit path extends from a cylindrical space between the inner and intermediate tubes, through the central-body, and through a wall of the exit cone. The inner tube of each arm assembly includes an auger. An electric motor drives the drive shaft. A hydraulic motor drives the auger. An oxidation reactor in a centrifuge for decanting lighter material from heavier material from a mixture of initial material and to perform an oxidation reaction process on the heavier material.

摘要翻译： 双管离心机从输入混合物中分离出轻质材料和重质材料。 中空驱动轴围绕旋转轴线旋转中心体部件。 两个具有圆形横截面的中空臂组件安装在中心体的直径相对的两侧。 每个臂组件包括外壳体管，中间管和比中间管长的内管。 具有可拆卸插头的端盖安装在每个臂组件的壳体管的外端上。 所有三个管的内端机械地互锁，以悬臂将内管和中间管安装到中心体，其外端与端盖的内表面间隔开。 输入混合路径穿过中空驱动轴穿过中心体，并且延伸到每个臂组件的内管和中间管之间的圆柱形空间中。 重材料出口路径从内管延伸穿过中心体并且延伸到与驱动轴直径相对并且其轴线与旋转轴线重合的出口锥体。 轻材料出口路径从内管和中间管之间的圆柱形空间延伸穿过中心体，并穿过出口锥体的壁。 每个臂组件的内管包括螺旋钻。 电动机驱动驱动轴。 液压马达驱动螺旋钻。 在离心机中的氧化反应器，用于从较重的材料从初始材料的混合物中倾倒较轻的材料，并在较重的材料上进行氧化反应过程。

公开(公告)号：US20030216238A1

公开(公告)日：2003-11-20

申请号：US10386716

申请日：2003-03-13

申请人： HITACHI KOKI CO., LTD.

发明人： Kenji Yamada ,  Kazuhiko Murayama ,  Daijiro Shiraishi

IPC分类号： B04B005/02 ,  B04B015/06

CPC分类号： B04B5/0421 ,  B04B15/06 ,  B04B15/12

摘要： A bio cell cleaning rotor assembled in a centrifuge. The rotor includes a plurality of test tube holders for holing a plurality of test tubes. The holders are pivotally movably supported to a rotor body so that the test tube holders are moved toward a horizontal direction upon application of centrifugal force. A cleaning liquid distributor is positioned above the rotor and is rotatable together with the rotor for distributing even amount of cleaning liquid to the plurality of test tubes. The distributor includes a disc like upper segment and a disc like lower segment in opposition thereto. The upper and lower distribution segments are molded products and have radially outer side flat sections in intimate contact with each other. A plurality of radial grooves are formed in at least one of the flat sections. The radial grooves serving as cleaning liquid distribution nozzles each having radially outer end open toward each opening of each test tube.

摘要翻译： 组装在离心机中的生物细胞清洁转子。 转子包括多个试管保持器，用于使多个试管穿孔。 保持器可枢转地移动地支撑在转子体上，使得试管保持器在施加离心力时向水平方向移动。 清洁液分配器位于转子上方并与转子一起旋转，用于将均匀的清洗液体分配到多个试管中。 分配器包括盘状的上段和与其相对的像下段的盘。 上部和下部分配段是模制产品，并且具有彼此紧密接触的径向外侧平坦部分。 在至少一个平坦部分中形成多个径向槽。 用作清洁液体分配喷嘴的径向凹槽各自具有朝向每个试管的每个开口的径向外端开口。

公开(公告)号：US20030186798A1

公开(公告)日：2003-10-02

申请号：US10105624

申请日：2002-03-26

发明人： Masaharu Aizawa

IPC分类号： B04B005/02

CPC分类号： B04B5/0421

摘要： A plurality of buckets are swingably supported in a rotor body. Each of the buckets, holding a boxlike sample container, is brought into contact with an inside surface of an outer wall of the rotor body due to a centrifugal force when the rotor rotates. The buckets and the rotor body integrally rotate during centrifugal operation.

摘要翻译： 多个铲斗可摆动地支撑在转子体中。 当转子旋转时，由于离心力而使容纳有箱状样品容器的桶中的每一个与转子体的外壁的内表面接触。 在离心操作期间，铲斗和转子主体一体旋转。