公开(公告)号：US06207864B1

公开(公告)日：2001-03-27

申请号：US09380382

申请日：1999-09-01

申请人： Michael Henningsen ,  Armin Stamm ,  Martin Fischer ,  Wolfgang Siegel

发明人： Michael Henningsen ,  Armin Stamm ,  Martin Fischer ,  Wolfgang Siegel

IPC分类号： C07C4530

CPC分类号： C07F9/535 ,  C07C1/30 ,  C07C17/00 ,  C07C17/18 ,  C07C2601/02 ,  C07C13/04 ,  C07C22/00

摘要： The invention relates to a process for the halogenation of cyclopropylmethyl ketone with at least one dihalo-triorganophosphorane of the general formula I R3PHal2   (I), in which the radicals R can be the same or different and denote a saturated or unsaturated aliphatic C1-C20 hydrocarbon radical, a phenyl or (C1-C4 alkyl)phenyl radical, which may be optionally substituted by one or two fluorine, chlorine and/or nitro groups, P stands for phosphorus and Hal denotes chlorine, bromine, or iodine, at a temperature of from 800° to 130° C., where the dihalo-triorganophosphane of the general formula (I) is synthesized in situ from triorganophosphane oxide or triorganophosphane sulfide of the general formula II R3PA   (II), in which R is as defined above with respect to formula I and A denotes oxygen or sulfur, using a halogenating agent, wherein the triorganophosphane oxide or triorganophosphane sulfide is used in catalytic amounts, to the halogenation product of cyclopropylmethyl ketone obtained in said process, and to a process for the conversion of said halogenation product to cyclopropylacetytene.

摘要翻译： 本发明涉及用至少一种通式Iin的二卤代三有机基磷烷卤化环丙基甲基酮的方法，其中基团R可以相同或不同，表示饱和或不饱和的脂族C 1 -C 20烃基，苯基或 （C 1 -C 4烷基）苯基，其可任选被一个或两个氟，氯和/或硝基取代，P代表磷，Hal代表氯，溴或碘，温度为800°至130° ℃，其中通式（I）的二卤代三有机膦原位由通式IIin的三有机膦氧化物或三有机磷烷硫化物原位合成，其中R如对于式I所定义，A表示氧或硫，使用 一种卤化剂，其中三有机膦氧化物或三有机基硫化物以催化量使用于在所述方法中获得的环丙基甲基酮的卤化产物，t o将所述卤化产物转化为环丙基乙烯基的方法。

公开(公告)号：US06822123B2

公开(公告)日：2004-11-23

申请号：US10405564

申请日：2003-04-02

申请人： John E. Stauffer

发明人： John E. Stauffer

IPC分类号： C07C4530

CPC分类号： C07C45/32 ,  C07C45/38 ,  C07C47/04

摘要： A process is provided for the production of formaldehyde from methyl chloride. In the process methyl chloride is oxidized with air over a catalyst to give formaldehyde and hydrogen chloride. In a preferred embodiment of the invention, a mixture of two different catalysts is used, one catalyst to promote the hydrolysis of methyl chloride to methyl alcohol, and the other catalyst to oxidize the methyl alcohol so formed to formaldehyde. The reaction kinetics can be regulated by adjusting the proportion of the two catalysts in the mixture. In this manner, the release of heat from the reaction can be controlled and excessive temperatures in the catalyst mixture can be avoided.

摘要翻译： 提供了用于从氯甲烷生产甲醛的方法。 在此过程中，甲基氯在空气中被催化剂氧化，得到甲醛和氯化氢。 在本发明的优选实施方案中，使用两种不同催化剂的混合物，一种用于促进甲基氯水解成甲醇的催化剂，另一种催化剂将如此形成的甲醇氧化成甲醛。 可以通过调节混合物中两种催化剂的比例来调节反应动力学。 以这种方式，可以控制反应中释放的热量，并且可以避免催化剂混合物中过多的温度。

公开(公告)号：US06525226B2

公开(公告)日：2003-02-25

申请号：US10187183

申请日：2002-07-01

申请人： Vasant Ram chandra Choudhary ,  Suman Kumar Jana

发明人： Vasant Ram chandra Choudhary ,  Suman Kumar Jana

IPC分类号： C07C4530

CPC分类号： C07C41/30 ,  C07C2/861 ,  C07C2/864 ,  C07C45/46 ,  C07C201/12 ,  C07C2521/10 ,  C07C2523/08 ,  C07C2527/236 ,  C07C2603/24 ,  C07C15/16 ,  C07C49/784 ,  C07C49/83 ,  C07C49/84 ,  C07C49/786 ,  C07C205/06 ,  C07C15/12 ,  C07C15/28 ,  C07C43/205

摘要： A process for Friedel-Crafts type liquid-phase alkylation or acylation of an aromatic compound using a hydrotalcite-type basic anionic clay catalyst represented by a formula: [(M2+)1−x(M3+)x(OH)2]x+[Ay−]x/y q H2O where M2+ is a divalent cation selected from Mg2+, Zn2+, Ni2+, Co2+, Mn2+, Cu2+ or a mixture thereof, M3+ is a trivalent cation selected from Ga3+, In3+ Al3+, Fe3+ Cr3+ or a mixture thereof; x is a mole fraction of trivalent cations in the range of about 0.05 to about 0.5; O is oxygen; H is hydrogen; Ay− is an anion; y minus is an anionic negative charge having a value of 1 minus or 2 minus; and q is a number of water molecules, as the water of hydration; and involving following steps: i. pretreating said catalyst by contacting it with a halogen containing compound in the presence or absence of a non-aqueous solvent and optionally washing the pretreated catalyst with non-aqueous solvent or liquid aromatic compound to be alkylated or acylated; and then ii. contacting a liquid reaction mixture comprising said aromatic compound and said alkylating or acylating agent in the presence or absence of a non-aqueous solvent with the catalyst obtained from step (i) in a stirred batch reactor fitted with a reflux condenser under vigorous stirring, in the presence or absence of an inert gas bubbling through the reaction mixture, at effective reaction conditions; iii. cooling the reaction mixture to a temperature about 30° C., removing said catalyst from the reaction mixture by filtration and then separating the reaction products from the reaction mixture, and optionally washing the used catalyst by non-aqueous solvent; and if desired, iv. reusing the used catalyst directly with or without drying for the subsequent reaction batch avoiding step (i), is disclosed.

摘要翻译： 使用由下式表示的水滑石型碱性阴离子粘土催化剂，使用Friedel-Crafts型液相烷基化或芳族化合物酰化的方法：其中M2 +是选自Mg2 ​​+，Zn2 +，Ni2 +，Co2 +，Mn2 +，Cu2 +或 其混合物，M3 +是选自Ga3 +，In3 + Al3 +，Fe3 + Cr3 +或其混合物的三价阳离子; x是三价阳离子在约0.05至约0.5范围内的摩尔分数; O是氧; H是氢; Ay-是阴离子; y minus是具有值1或2减去的阴离子负电荷; 和q是水分子的数量，作为水合水; 并涉及以下步骤：i。 在存在或不存在非水溶剂的情况下，通过使其与含卤素的化合物接触来预处理所述催化剂，并任选地用待进行烷基化或酰化的非水溶剂或液体芳族化合物洗涤预处理的催化剂; 然后。 在非水溶剂存在或不存在下，将含有所述芳族化合物和所述烷基化或酰化剂的液体反应混合物与步骤（i）获得的催化剂在剧烈搅拌下在装有回流冷凝器的搅拌间歇式反应器中接触， 在有效的反应条件下存在或不存在通过反应混合物鼓泡的惰性气体; iii。 将反应混合物冷却至约30℃的温度，通过过滤从反应混合物中除去所述催化剂，然后将反应产物与反应混合物分离，并任选地通过非水溶剂洗涤所用催化剂; 如果需要，iv。 公开了直接使用或不用干燥后续反应批次的用过的催化剂，以避免步骤（i）。