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1.Derivatives and analogues of 2-deoxy-2,3-didehydro-n-acetyl neuraminic acid and their use as antiviral agents 失效
标题翻译: 2-脱氧-2,3-二脱氢-N-乙酰神经氨酸的衍生物和类似物及其作为抗病毒剂的用途公开(公告)号:US5648379A
公开(公告)日:1997-07-15
申请号:US325074
申请日:1994-10-19
申请人: Laurence Mark Von Itzstein , Wen-Yang Wu , Tho Van Phan , Basil Danylec , Betty Jin , Peter Malcolm Colman , Joseph Noozhumurry Varghese
发明人: Laurence Mark Von Itzstein , Wen-Yang Wu , Tho Van Phan , Basil Danylec , Betty Jin , Peter Malcolm Colman , Joseph Noozhumurry Varghese
IPC分类号: C07D309/30 , A61K31/00 , A61K31/196 , A61K31/34 , A61K31/35 , A61K31/351 , A61K31/38 , A61K31/382 , A61K31/41 , A61K31/435 , A61K31/44 , A61K31/505 , A61K31/7012 , A61P31/00 , A61P31/12 , A61P31/14 , C07C47/225 , C07C47/42 , C07C225/20 , C07C233/52 , C07C309/25 , C07C317/12 , C07C321/22 , C07D20060101 , C07D211/70 , C07D211/72 , C07D211/74 , C07D211/78 , C07D211/84 , C07D239/26 , C07D257/02 , C07D257/04 , C07D309/20 , C07D309/22 , C07D309/26 , C07D309/28 , C07D335/02 , C07D401/04 , C07D401/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/14 , C07D498/04 , C07F9/655 , C07H7/033 , C07C309/20
CPC分类号: C07D309/30 , C07D309/28
摘要: Derivatives and analogues of 2-deoxy-2,3-didehydro-N-acetyl neuraminic acid, pharmaceutical formulations thereof, methods for their preparation and their use in the treatment of viral infections, in particular influenza, are described.
摘要翻译: 描述了2-脱氧-2,3-二脱氢-N-乙酰神经氨酸的衍生物和类似物,其药物制剂,其制备方法及其在治疗病毒感染,特别是流感中的用途。
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公开(公告)号:US3119844A
公开(公告)日:1964-01-28
申请号:US22383662
申请日:1962-09-14
申请人: SHELL OIL CO
IPC分类号: C07D309/26
CPC分类号: C07D309/26
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公开(公告)号:US2800488A
公开(公告)日:1957-07-23
申请号:US51764855
申请日:1955-06-23
申请人: UNION CARBIDE CORP
发明人: GUEST HOWARD R , KIFF BEN W
IPC分类号: C07D309/26
CPC分类号: C07D309/26
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4.
公开(公告)号:US20200239398A1
公开(公告)日:2020-07-30
申请号:US16714746
申请日:2019-12-15
IPC分类号: C07C57/26 , A61P25/28 , C07D211/70 , C07D309/26 , C07D335/02 , C07C59/82 , C07C255/31
摘要: Methylene-cycloalkylacetate compounds and derivatives thereof and their use in methods for treatment of neurotropic conditions.
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公开(公告)号:US3084169A
公开(公告)日:1963-04-02
申请号:US6285360
申请日:1960-10-17
申请人: SHELL OIL CO
IPC分类号: C07D309/26 , C08F2/38
CPC分类号: C07D309/26 , C08F2/38
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公开(公告)号:US2537579A
公开(公告)日:1951-01-09
申请号:US10942449
申请日:1949-08-09
申请人: SHELL DEV
发明人: FOUNTAIN EUGENE B , SHARP WALTER H
IPC分类号: C07D309/26
CPC分类号: C07D309/26
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公开(公告)号:US2479283A
公开(公告)日:1949-08-16
申请号:US71345546
申请日:1946-12-02
申请人: SHELL DEV
发明人: WHETSTONE RICHARD R
IPC分类号: C07D309/06 , C07D309/26 , C07D309/28
CPC分类号: C07D309/06 , C07D309/26 , C07D309/28
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公开(公告)号:US09382501B2
公开(公告)日:2016-07-05
申请号:US14767560
申请日:2014-02-04
申请人: FIRMENICH SA
发明人: Julien Coulomb
IPC分类号: C11B9/00 , A61Q5/06 , A61Q15/00 , C11D3/20 , C11D3/50 , A61K8/49 , C07D309/26 , C07D309/06
CPC分类号: C11B9/008 , A61K8/498 , A61Q5/06 , A61Q15/00 , C07D309/06 , C07D309/26 , C11D3/2096 , C11D3/50
摘要: The present invention relates to a composition of matter comprising 1) at least 70% of at least a compound of formula (I) in the form of any one of its stereoisomers or a mixture thereof, and wherein R represents —a hydrogen atom and the dotted line represents a carbon-carbon single or double bond; or —a CH2 group bonded with C4 and C5 and the dotted line represents a carbon-carbon single bond; 2) at most 30% of at least a compound of formula (II) in the form of any one of its stereoisomers or a mixture thereof, and wherein R represents —a hydrogen atom and the dotted line represents a carbon-carbon single or double bond; or —a CH2 group bonded with C4 and C5 and the dotted line represents a carbon-carbon single bond; and wherein the percentages are w/w percentages relative to the total weight of the composition. Said compositions are useful perfuming ingredients of the floral, lily of the valley type.
摘要翻译: 本发明涉及一种物质组合物,其包含1)至少70%的至少一种其立体异构体中任何一种形式的式(I)化合物或其混合物,其中R表示氢原子和 虚线表示碳 - 碳单键或双键; 或-a与C4和C5键合的CH2基,虚线表示碳 - 碳单键; 2)至少30%的至少一种其立体异构体或其混合物中任何一种形式的式(II)化合物,其中R表示氢原子,虚线表示碳 - 碳单或双 键; 或-a与C4和C5键合的CH2基,虚线表示碳 - 碳单键; 并且其中百分数相对于组合物的总重量为w / w百分比。 所述组合物是花卉,谷类的百合的有用的加香成分。
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9.Derivatives and analogues of 2-deoxy-2,3-didehydro-N-acetyl neuraminic acid and their use as antiviral agents 失效
标题翻译: 2-脱氧-2,3-二脱氢-N-乙酰神经氨酸的衍生物和类似物及其作为抗病毒剂的用途公开(公告)号:US5360817A
公开(公告)日:1994-11-01
申请号:US946327
申请日:1992-11-10
申请人: Laurence M. von Izstein , Wen-Yang Wu , Tho V. Phan , Basil Danylec , Betty Jin
发明人: Laurence M. von Izstein , Wen-Yang Wu , Tho V. Phan , Basil Danylec , Betty Jin
IPC分类号: C07D309/30 , A61K31/00 , A61K31/196 , A61K31/34 , A61K31/35 , A61K31/351 , A61K31/38 , A61K31/382 , A61K31/41 , A61K31/435 , A61K31/44 , A61K31/505 , A61K31/7012 , A61P31/00 , A61P31/12 , A61P31/14 , C07C47/225 , C07C47/42 , C07C225/20 , C07C233/52 , C07C309/25 , C07C317/12 , C07C321/22 , C07D20060101 , C07D211/70 , C07D211/72 , C07D211/74 , C07D211/78 , C07D211/84 , C07D239/26 , C07D257/02 , C07D257/04 , C07D309/20 , C07D309/22 , C07D309/26 , C07D309/28 , C07D335/02 , C07D401/04 , C07D401/14 , C07D405/04 , C07D405/14 , C07D409/04 , C07D409/14 , C07D498/04 , C07F9/655 , C07H7/033
CPC分类号: C07D309/30 , C07D309/28
摘要: Derivatives and analogues of 2-deoxy-2,3-didehydro-N-acetyl neuraminic acid, pharmaceutical formulations thereof, methods for their preparation .and their use in the treatment of viral infections, in particular influenza, are described.
摘要翻译: PCT No.PCT / AU91 / 00161 Sec。 371日期:1992年11月10日 102(e)日期:1992年11月10日PCT 1991年4月24日PCT PCT。 WO91 / 16320 PCT公开号 日期:1991年10月31日。2-脱氧-2,3-二脱氢-N-乙酰神经氨酸的衍生物和类似物,其药物制剂,其制备方法及其在治疗病毒感染中的用途,特别是流感, 被描述。
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公开(公告)号:US3159651A
公开(公告)日:1964-12-01
申请号:US21142762
申请日:1962-07-20
申请人: SHELL OIL CO
IPC分类号: C07D309/26
CPC分类号: C07D309/26
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