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    Device for referencing fluorescence signals
    1.
    发明申请
    Device for referencing fluorescence signals 有权
    参考荧光信号的装置

    公开(公告)号：US20040196455A1

    公开(公告)日：2004-10-07

    申请号：US10472974

    申请日：2004-05-24

    Inventor： Eugen Ermantraut ,  Thomas Kaiser ,  Jens Tuchscheerer

    IPC: G01J001/10

    CPC classification number: G01N21/6452 ,  G01N21/278

    Abstract: The invention relates to a device for referencing fluorescence signals and/or calibration of fluorescence detection systems, whereby the device comprises an essentially non-fluorescing support, on which are applied polymer layers in several defined regions and with partly varying thicknesses and/or compositions. Said polymer layers are applied to the support such as to fluoresce after corresponding irradiation and the device may thus be used as a fluorescence standard. The invention further relates to a method for the production of said fluorescence standards.

    Abstract translation: 本发明涉及一种用于参考荧光信号和/或校准荧光检测系统的装置，由此该装置包括基本上不发荧光的载体，其上在几个限定区域中施加聚合物层并且具有部分变化的厚度和/或组成。 所述聚合物层被施加到载体上，以便在相应的照射后发荧光，因此该装置可以用作荧光标准。 本发明还涉及生产所述荧光标准品的方法。

    Electromagnetic radiation attenuating and scattering member with improved thermal stability
    2.
    发明申请
    Electromagnetic radiation attenuating and scattering member with improved thermal stability 有权
    具有改善的热稳定性的电磁辐射衰减和散射构件

    公开(公告)号：US20040008343A1

    公开(公告)日：2004-01-15

    申请号：US10321510

    申请日：2002-12-18

    Applicant: CME TELEMETRIX, INC.

    Inventor： Romuald Pawluczyk ,  Theodore Cadell ,  Bronislaw Bednarz ,  Ashwani Kaushal

    IPC: G01J001/10

    CPC classification number: G02B5/0294 ,  G02B5/0278 ,  G02B7/008

    Abstract: The present invention provides a thermally stable reference member comprising, at least one radiation attenuating element and at least one radiation scattering element. The radiation attenuating element comprising at least one aperture for transmission of radiation therethrough. The attenuating and scattering elements placed in series so that radiation transmitted through the reference member passes through each of the attenuating and scattering elements. The attenuating and scattering elements of the reference member may further comprise a thermally stable mount to hold the elements in a selected position relative to each other, and in relation to an instrument, or the elements may be bonded together. The radiation attenuating element may be comprised of a material selected from the group consisting of INVAR, tungsten, brass, and a material substantially non-transparent for incident radiation, and the radiation scattering element may be comprised of a radiation scattering material selected from the group consisting of opalescent glass, SPECTRALON, PTFE, ZERODUR, fused silica, quartz, sapphire, diamond, and a transparent material with essentially low thermal expansion.

    Abstract translation: 本发明提供了一种热稳定的参考构件，其包括至少一个辐射衰减元件和至少一个辐射散射元件。 所述辐射衰减元件包括用于透射辐射的至少一个孔。 衰减和散射元件串联放置，使得透射通过参考构件的辐射通过每个衰减和散射元件。 参考构件的衰减和散射元件还可以包括热稳定的安装件，以将元件保持在相对于彼此的选定位置，并且相对于仪器，或者元件可以结合在一起。 辐射衰减元件可以由选自I NVAR ，钨，黄铜以及对于入射辐射基本不透明的材料组成的组成，并且辐射散射元件可以由 选自乳光玻璃，S PECTRALON ，PTFE，Z ERODUR ，熔融石英，石英，蓝宝石，金刚石和透明材料的辐射散射材料，基本上 低热膨胀。

    Calibration apparatus, system and method
    3.
    发明申请
    Calibration apparatus, system and method 审中-公开
    校准装置，系统和方法

    公开(公告)号：US20030038933A1

    公开(公告)日：2003-02-27

    申请号：US10126187

    申请日：2002-04-19

    Applicant: Dimensional Photonics Inc.

    Inventor： Lyle G. Shirley ,  Gary J. Swanson ,  Nathan D. Derr

    IPC: G01J001/10

    CPC classification number: G01B11/25 ,  G01B11/2504 ,  G01B21/042 ,  G01N21/278

    Abstract: An aspect of the invention relates to a calibration standard for a three-dimensional measurement system and various calibration methods and techniques. The calibration standard typically includes a calibration standard surface and a plurality of optical targets. The optical targets being are affixed to the calibration standard surface and define a three-dimensional distribution of optical reference points. The optical targets can be serve as active, passive calibration targets, or combinations of both. In one embodiment, the optical targets include an optical source and a diffusing target, and each of the optical sources are configured to illuminate the respective diffusing target. The optical targets can be removably affixed to the calibration standard surface.

    Abstract translation: 本发明的一个方面涉及三维测量系统的校准标准和各种校准方法和技术。 校准标准通常包括校准标准表面和多个光学靶。 光学靶被固定在校准标准表面上并且限定光学参考点的三维分布。 光学目标可以用作主动，被动校准目标或两者的组合。 在一个实施例中，光学目标包括光源和扩散目标，并且每个光源被配置为照射相应的扩散目标。 光学靶可以可拆卸地固定在校准标准表面上。

    Roundness standard
    6.
    发明申请
    Roundness standard 审中-公开
    圆度标准

    公开(公告)号：US20040075829A1

    公开(公告)日：2004-04-22

    申请号：US10182795

    申请日：2002-12-05

    Inventor： Kostadin Doytchinov ,  Jim Pekelsky ,  Lorne Munro

    IPC: G01J001/10

    CPC classification number: G01B3/303 ,  G01B5/201

    Abstract: A roundness calibration device includes a ring or plug gauge with a wall defining an arcuate surface traversable by a sensing probe. A protuberance, typically in the form of a piston, is displaceably mounted in a radial bore in the wall. A displacement device adjusts the amount of protrusion of said protuberance to locally, radially modify the arcuate surface. A calibrated measuring device accurately determines the amount of protrusion.

    Abstract translation: 圆度校准装置包括具有壁的环或塞规，所述壁限定可由感测探针穿过的弓形表面。 通常为活塞形式的突起可移动地安装在壁的径向孔中。 位移装置将所述突起的突出量局部调整，径向地修改弓形表面。 校准的测量装置精确地确定突出量。

    Spatial reference system
    7.
    发明申请
    Spatial reference system 有权
    空间参考系

    公开(公告)号：US20040066508A1

    公开(公告)日：2004-04-08

    申请号：US10675788

    申请日：2003-09-30

    Inventor： Ingobert Schmadel

    IPC: G01J001/10 ,  G01B011/24

    CPC classification number: G01B21/042

    Abstract: The present invention overcomes the disadvantages of the related art by providing a spatial reference system that includes at least one artifact assembly. The artifact assembly has a measuring bar assembly including an inner member with a proximate end and a distal end, an outer member with a proximate end and a distal end, and a compensating member with a proximate end and a distal end operatively disposed between said inner and said outer members. The distal end of the outer member is fixedly mounted to the distal end of the compensating member. The proximate end of the compensating member is fixedly mounted to the proximate end of the inner member. The inner and the outer members each have a predetermined length and a predetermined coefficient of thermal expansion and the compensating member has a predetermined length and a predetermined coefficient of thermal expansion, such that the thermal expansion of the inner and the outer members is substantially eliminated by the expansion of the compensating member.

    Abstract translation: 本发明通过提供包括至少一个假象组件的空间参考系统来克服现有技术的缺点。 所述人造物组件具有测量杆组件，其包括具有近端和远端的内部构件，具有近端和远端的外部构件以及具有近端和远端的补偿构件，所述近端和远端可操作地设置在所述内部 并表示外部构件。 外部构件的远端固定地安装到补偿构件的远端。 补偿构件的近端固定地安装到内构件的近端。 内部构件和外部构件各自具有预定长度和预定热膨胀系数，并且补偿构件具有预定长度和预定热膨胀系数，使得内部构件和外部构件的热膨胀基本上被 补偿构件的膨胀。

    Method for checking the operation of an optical measuring device and checking device
    8.
    发明申请
    Method for checking the operation of an optical measuring device and checking device 有权
    用于检查光学测量装置和检查装置的操作的方法

    公开(公告)号：US20030086085A1

    公开(公告)日：2003-05-08

    申请号：US10233676

    申请日：2002-09-04

    Inventor： Raimo Harju ,  Sanna Tauluvuori

    IPC: G01J001/10

    CPC classification number: G01N21/274

    Abstract: A method for checking the operation of a laboratory instrument used in biochemistry by means of an individual test plate (10) by comparing measured values of sample units (20, 21) placed in the wells (12) of the frame plate (11) to previously known measured values verified by a reference device. The sample unit (20) placed in the frame plate (11) of the test plate (10) is a teflon plastic cup (22) provided with an aluminum cover (23), the sample material (24) in powdery form being placed in said cup, or an optical filter (21), which is locked in place by means of a locking spring ring (25).

    Abstract translation: 一种用于通过将放置在框架板（11）的孔（12）中的样品单元（20,21）的测量值与通过将框架板（11）的孔（12）中的样品单元（20,21）的测量值相比较来测量生物化学中使用的实验室仪器的操作的方法， 先前已知的测量值由参考设备验证。 放置在测试板（10）的框架板（11）中的样品单元（20）是设置有铝盖（23）的聚四氟乙烯塑料杯（22），将粉末形式的样品材料（24）放置在 所述杯子或光学过滤器（21），其通过锁定弹簧环（25）锁定就位。

    Blanking standard for non-invasive optical measurement
    9.
    发明申请
    Blanking standard for non-invasive optical measurement 审中-公开
    非侵入性光学测量的消隐标准

    公开(公告)号：US20030011764A1

    公开(公告)日：2003-01-16

    申请号：US09971312

    申请日：2001-10-03

    Inventor： James R. Braig ,  Julian M. Cortella ,  Mike A. Munrow ,  Kenneth G. Witte ,  Heidi M. Smith ,  Philip C. Hartstein ,  Roger O. Herrera ,  Peter Rule

    IPC: G01J001/10

    CPC classification number: A61B5/1495 ,  A61B5/14532 ,  A61B5/1455 ,  A61B2560/0233

    Abstract: In accordance with one embodiment there is provided a method of providing a known spectrum to a noninvasive optical detection system of the type having a window for receiving infrared energy. The method comprises affixing a standard to the window. The standard comprises a body formed from a material having known and stable spectral properties. The method further comprises placing at least a portion of the body directly against the window, and operating the optical detection system to detect an emission spectrum of the body. In accordance with another embodiment an infrared spectrometer comprises a window for receiving infrared energy. The window has an exposed surface. The infrared spectrometer further comprises a standard comprising a body formed of a material having known and stable spectral properties. At least part of the body is removably disposed directly against the exposed surface of the window.

    Abstract translation: 根据一个实施例，提供了一种向具有用于接收红外能量的窗口的类型的无创光学检测系统提供已知光谱的方法。 该方法包括将标准附加到窗口。 该标准包括由具有已知且稳定的光谱性质的材料形成的主体。 该方法还包括将身体的至少一部分直接放置在窗户上，并且操作光学检测系统以检测身体的发射光谱。 根据另一实施例，红外光谱仪包括用于接收红外能量的窗口。 窗户有一个暴露的表面。 红外光谱仪还包括标准，其包括由具有已知且稳定的光谱性质的材料形成的主体。 身体的至少一部分可拆卸地直接设置在窗户的暴露表面上。

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