利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

5180 条记录 (耗时 0.038 秒)

    Cannabinoid Product for Control of Pre-diabetic Markers
    2.
    发明申请
    Cannabinoid Product for Control of Pre-diabetic Markers 有权

    公开(公告)号：US20230137614A1

    公开(公告)日：2023-05-04

    申请号：US17694910

    申请日：2022-03-15

    申请人： ECS Brands Ltd.

    发明人： Arthur Jaffee

    IPC分类号： A61K31/352 ,  A61K31/05 ,  A61K47/44

    摘要： Cannabinoids are increasingly found to have beneficial effects on the human body, even without the intoxicating effects from THC. Herein we describe a cannabinoid which is used to assist with control of pre-diabetic markers in the individual taking the cannabinoid. Tetrahydrocannabivarin, typically but not necessarily combined with assorted cannabinoids, provides a product for control of pre-diabetic markers without the need for diet or exercise.

    SUBLINGUAL CANNABINOID COMPOSITIONS
    3.
    发明申请
    SUBLINGUAL CANNABINOID COMPOSITIONS 有权

    公开(公告)号：US20230134563A1

    公开(公告)日：2023-05-04

    申请号：US18073347

    申请日：2022-12-01

    申请人： ALVIT LCS PHARMA LTD.

    发明人： Yoram SELA ,  Itschak LAMENSDORF ,  Nachshol COHEN

    IPC分类号： A61K31/352 ,  A61K31/05 ,  A61K45/06 ,  A61K47/32 ,  A61K47/38 ,  A61K47/36 ,  A61K47/34 ,  A61K9/00

    摘要： The present invention provides a composition for a sublingual or a buccal delivery of cannabinoid active ingredients comprising a therapeutically effective dose of at least one cannabinoid, an emulsifying and penetration enhancing solubilizer such as vitamin E TPGS, Menthol as a permeation enhancer at 1-50 mg/dose, and polyethylene oxide as a mucoadhesive polymer at 2-100 mg, whereby the composition is administered sublingually or buccally in the form of tablet or film, and whereby the emulsifying and penetration enhancing solubilizer is present in an amount equal to or larger than 50% of the amount of the cannabinoid. The present invention further provides a composition for a sublingual or a buccal delivery of cannabinoid active ingredients comprising a therapeutically effective dose of at least one cannabinoid in a mucoadhesive dosage form, comprising sublingual tablets or films and having greater bioavailability than an alcohol-based oral spray having 5.2 mg/per spray of cannabinoid active ingredients.

    COMPOSITIONS AND METHODS FOR IMMUNE-MEDIATED CANCER THERAPY
    4.
    发明申请
    COMPOSITIONS AND METHODS FOR IMMUNE-MEDIATED CANCER THERAPY 有权

    公开(公告)号：US20230133566A1

    公开(公告)日：2023-05-04

    申请号：US17991154

    申请日：2022-11-21

    申请人： Teclison Limited

    发明人： Ruey-min Lee

    IPC分类号： A61K31/53 ,  A61K35/17 ,  A61K39/395 ,  C07K16/28 ,  A61K31/09 ,  A61K31/485 ,  A61P35/00 ,  A61K31/05 ,  A61K31/136 ,  A61K31/27 ,  A61K31/352

    摘要： Disclosed herein are methods and compositions for enhancing an immune response to a solid tumor in a subject. In some embodiments, a method comprises: (a) administering to the subject a hypoxia-activated bioreductive agent (HABA); (b) inducing hypoxia by (i) administering a hypoxia-inducing agent to the subject or (ii) embolizing one or more blood vessels supplying the solid tumor; and (c) administering an immune checkpoint inhibitor prior to, simultaneously with, or subsequent to step (b) in an amount effective to enhance an immune response to the solid tumor, as compared to an immune response in the absence of the immune checkpoint inhibitor. Kits for use in the disclosed methods are also provided.

    Flavor elements and methods of providing nonvaporized flavor to electronic vaporizers and e-cigarettes
    9.
    发明授权
    Flavor elements and methods of providing nonvaporized flavor to electronic vaporizers and e-cigarettes 有权

    公开(公告)号：US11632985B2

    公开(公告)日：2023-04-25

    申请号：US16709555

    申请日：2019-12-10

    申请人： Darren Rubin

    发明人： Darren Rubin

    IPC分类号： A24F40/30 ,  A24F40/20 ,  A24B15/167 ,  A23G3/34 ,  A61K36/185 ,  A61K31/05 ,  A61K31/352

    摘要： The present disclosure describes a flavor element configured for providing flavor to a user of an electronic vaporizer, along with nicotine reduction methods. The flavor element includes a flavor material configured to provide the flavor and is configured to attach to the electronic vaporizer. When attached to the electronic vaporizer and during inhalation by the user using the electronic vaporizer, the flavor element is configured to provide the flavor to the user in parallel with an inhalable aerosol provided by the electronic vaporizer. The inhalable aerosol is provided by the electronic vaporizer by at least partially vaporizing a vaporizable substance via a vapor element. The flavor provided via the flavor material is separate from the vaporizable substance.