公开(公告)号：US20240081814A1

公开(公告)日：2024-03-14

申请号：US18517420

申请日：2023-11-22

申请人： W. L. Gore & Associates, Inc.

发明人： Tiffany Gemetta ,  Rachel Radspinner ,  Elena Ten ,  Franklin C. Wetherell

IPC分类号： A61B17/06 ,  A61B17/04 ,  A61F2/24 ,  A61L17/14 ,  C08F114/26 ,  C08F214/26 ,  C08F216/14

CPC分类号： A61B17/06166 ,  A61B17/0469 ,  A61F2/2457 ,  A61L17/145 ,  C08F114/26 ,  C08F214/262 ,  C08F216/1408 ,  A61B2017/06057 ,  A61F2002/0081 ,  A61F2/2466 ,  C08F2800/20

摘要： Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that include a cord that is flexible and elongated defining a length. The cord may include a core having a porous surface and a porosity-reducing element on at least a portion of the core.

公开(公告)号：US11890003B2

公开(公告)日：2024-02-06

申请号：US17371779

申请日：2021-07-09

申请人： Northwestern University

发明人： Gregory A. Dumanian

IPC分类号： A61B17/06 ,  A61L17/00 ,  A61L17/04 ,  A61L17/12 ,  A61L17/14 ,  A61B17/00 ,  A61B17/04

CPC分类号： A61B17/06166 ,  A61B17/06 ,  A61L17/00 ,  A61L17/04 ,  A61L17/12 ,  A61L17/145 ,  A61B2017/00526 ,  A61B2017/0412 ,  A61B2017/0417 ,  A61B2017/0461 ,  A61B2017/0464 ,  A61B2017/061 ,  A61B2017/0608 ,  A61B2017/06009 ,  A61B2017/06185 ,  Y10T29/49826

摘要： A medical device includes a surgical needle, an elongated suture, and an intervening segment. The elongated suture has a first end proximate to the needle and a second end located away from the needle. The elongated suture also includes a plurality of fibers defining a mesh wall between the first and second ends. A plurality of pores extend through the mesh wall, at least some which are in the macroporous size range of greater than 200 microns for facilitating tissue integration when introduced into a body. The intervening segment is disposed between and connected to either or both ends of the elongated suture and the needle. The intervening segment includes one or more fibers of the plurality of fibers and has a cross-sectional dimension smaller than a cross-sectional dimension of the mesh wall such that the intervening segment facilitates indirect attachment of the elongated macroporous mesh suture to the needle.

公开(公告)号：US20230397978A1

公开(公告)日：2023-12-14

申请号：US18031721

申请日：2021-10-13

申请人： University of Pittsburgh - Of the Commonwealth System of Higher Education

发明人： Rui Liang ,  Mostafa Bedewy ,  Eric Rafeek Shaker

IPC分类号： A61F2/00 ,  A61L17/14 ,  A61L17/00 ,  A61L31/08 ,  A61L31/04

CPC分类号： A61F2/0063 ,  A61L17/145 ,  A61L17/005 ,  A61L31/084 ,  A61L31/048 ,  A61L2300/404 ,  A61L2400/12

摘要： An implantable mesh device includes a surface layer on at least a portion thereof. The surface layer includes a plurality of extending members that mechanically interact with microbiota to disable the microbiota.

公开(公告)号：US20230256140A1

公开(公告)日：2023-08-17

申请号：US18308409

申请日：2023-04-27

申请人： MOZARC MEDICAL US LLC

发明人： Valentino Tramontano ,  Brent Marsden ,  Robert Almeida ,  Eric W. Dahl ,  James W. Rawlins ,  Sharathkumar K. Mendon

IPC分类号： A61L29/08 ,  A61L27/34 ,  A61L27/54 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16 ,  A61L17/14

CPC分类号： A61L29/085 ,  A61L17/145 ,  A61L27/34 ,  A61L27/54 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/45 ,  A61L2300/104 ,  A61L2300/206 ,  A61L2300/224 ,  A61L2300/404 ,  A61L2300/602 ,  A61L2420/02 ,  A61L2420/06

摘要： Antimicrobial formulations and coatings for medical devices and processes therefor are disclosed. The formulations include at least one water permeable polymer with at least one antimicrobial agent in a liquid medium and are prepared by wet milling the components and can form antimicrobial coatings having uniformly dispersed particles having an average size of no greater than 50 microns.

公开(公告)号：US20230233743A1

公开(公告)日：2023-07-27

申请号：US17989281

申请日：2022-11-17

申请人： The Regents of the University of California ,  Silq Technologies Corporation

发明人： Richard B. Kaner ,  Dayong Chen ,  Brian T. McVerry ,  Ethan Rao ,  Alexandra L. Polasko

IPC分类号： A61L31/10 ,  A61L27/34 ,  A61L29/08 ,  A61L27/54 ,  A61L29/16 ,  A61L31/16 ,  C09D5/00 ,  C09D133/14 ,  C09D183/04 ,  C08J3/24 ,  A61L17/14 ,  A01N41/06 ,  A01N33/12 ,  A01N33/20 ,  A61L17/00 ,  A01N33/00 ,  C08J7/04 ,  C08F220/38 ,  C08J7/056

CPC分类号： A61L31/10 ,  A61L27/34 ,  A61L29/085 ,  A61L27/54 ,  A61L29/16 ,  A61L31/16 ,  C09D5/00 ,  C09D133/14 ,  C09D183/04 ,  C08J3/245 ,  A61L17/145 ,  A01N41/06 ,  A01N33/12 ,  A01N33/20 ,  A61L17/005 ,  A01N33/00 ,  C08J7/0427 ,  C08F220/387 ,  C08J7/056 ,  C08F2810/20 ,  A61L2420/02 ,  A61L2300/408 ,  C08F2800/10 ,  A61L2300/404 ,  C08J2383/04 ,  C08J2433/14

摘要： Disclosed herein are compositions to use in biofouling-resistant coatings, biofouling-resistant coatings, methods of making biofouling-resistant coatings, biofouling-resistant devices, and methods of making biofouling-resistant devices.

公开(公告)号：US11684358B2

公开(公告)日：2023-06-27

申请号：US15083845

申请日：2016-03-29

申请人： Boston Scientific Scimed, Inc.

发明人： Peter J. Pereira ,  Jonathan Zoll

IPC分类号： A61B17/06 ,  A61B17/04 ,  A61L17/08 ,  A61L17/14 ,  A61F2/00 ,  A61B17/00 ,  A61L17/12

CPC分类号： A61B17/06166 ,  A61B17/0469 ,  A61F2/0045 ,  A61F2/0063 ,  A61L17/08 ,  A61L17/12 ,  A61L17/145 ,  A61B2017/005 ,  A61B2017/00955 ,  A61B2017/00964 ,  A61B2017/0619

摘要： This disclosure concerns suburethral and pelvic support structures which utilize tissue soldering materials instead of, or in addition to, traditional tissue anchors and suture knots. It further concerns methods of treating patients that includes implanting these structures and activating the tissue soldering materials to attach the structures to a tissue in the body of the patient.

公开(公告)号：US20230050983A1

公开(公告)日：2023-02-16

申请号：US17891487

申请日：2022-08-19

申请人： Egan Design LLC

发明人： Thomas D. EGAN

IPC分类号： A61B17/06 ,  B29C65/04 ,  A61B17/04 ,  A61L17/00 ,  A61L17/06 ,  A61L17/14 ,  B29C65/34 ,  B29C65/00 ,  B29C65/74 ,  A61B17/064 ,  A61B17/122

摘要： An apparatus for forming a weld between a first portion of a biocompatible conductive thermoplastic material and a second portion of a biocompatible conductive thermoplastic material comprises a first electrode, a second electrode, and a structure for holding said first and second electrodes in opposition to one other with a space therebetween for receiving said first portion and said second portion in contact with one another. The structure is electrically non-conductive and an electrical circuit comprising a power source and a switch arranged such that closure of said switch applies a voltage potential across said first electrode and said second electrode so as to generate heat via electrical resistance, the heat being sufficient to melt regions of said first and second portions.

公开(公告)号：US20230001042A1

公开(公告)日：2023-01-05

申请号：US17782458

申请日：2020-11-27

申请人： KEISEI MEDICAL INDUSTRIAL CO., LTD.

发明人： Jumpei Matsuda

IPC分类号： A61L17/14 ,  A61B17/06 ,  C07F9/09 ,  C08F30/02 ,  C08F230/02

摘要： Provided is a medical suture thread which is less likely to remain curled or is easily uncurled from a curled state. The medical suture thread 100 includes a core thread 110 and an outer thread 120. The core thread 110 includes multiple twisted ultrafine threads 111, and is arranged at a center portion of the medical suture thread 100. In the ultrafine thread 111, an inner-filament cover layer 112 made of 2-methacryloyloxyethyl phosphorylcholine (MPC) is formed on an outer surface of a filament 111a. The outer thread 120 is formed to be braided with multiple ultrafine threads 121, and covers an outer surface of the core thread 110. In the ultrafine thread 121, an outer-filament cover layer 122 made of MPC is formed on an outer surface of a filament 121a. The inner-filament cover layer 112 and the outer-filament cover layer 122 are respectively formed on the outer surfaces of the filaments 111a, 121a within a weight range of equal to or greater than 0.05% and less than 0.3% with respect to the total weight of each of the filaments 111a, 121a, respectively.

公开(公告)号：US20220054127A1

公开(公告)日：2022-02-24

申请号：US17371779

申请日：2021-07-09

申请人： Northwestern University

发明人： Gregory A. Dumanian

IPC分类号： A61B17/06 ,  A61L17/00 ,  A61L17/04 ,  A61L17/12 ,  A61L17/14

摘要： A medical device includes a surgical needle, an elongated suture, and an intervening segment. The elongated suture has a first end proximate to the needle and a second end located away from the needle. The elongated suture also includes a plurality of fibers defining a mesh wall between the first and second ends. A plurality of pores extend through the mesh wall, at least some which are in the macroporous size range of greater than 200 microns for facilitating tissue integration when introduced into a body. The intervening segment is disposed between and connected to either or both ends of the elongated suture and the needle. The intervening segment includes one or more fibers of the plurality of fibers and has a cross-sectional dimension smaller than a cross-sectional dimension of the mesh wall such that the intervening segment facilitates indirect attachment of the elongated macroporous mesh suture to the needle.

公开(公告)号：US11253626B2

公开(公告)日：2022-02-22

申请号：US16481662

申请日：2018-01-30

申请人： NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER ,  JMS CO., LTD.

发明人： Tetsuji Yamaoka ,  Maria Chiara Munisso ,  Atsushi Mahara ,  Takashi Yamamoto

IPC分类号： A61L17/14 ,  A61L17/10 ,  A61L27/16 ,  A61L27/28 ,  A61L27/50 ,  A61L31/04 ,  A61L31/08 ,  A61L33/12

摘要： Provided is a use for a peptide in surface-treating a medical device or medical material to be used in contact with blood, with which it is possible to obtain a medical device or medical material that can achieve highly efficient vascular endothelialization through the use of a peptide uniquely binding to vascular endothelial cells. Also provided are: a peptide suitable for use in said surface treatment; a method for producing a medical device or medical material surfaced-treated with said peptide and to be used in contact with blood; and a surface treatment agent including said peptide, said agent to be used in surface-treating a medical device or medical material to be used in contact with blood. In the present invention, a medical device or medical material is surface-treated using a peptide that includes any one of ten specific amino acid sequences and uniquely binds to the surface of endothelial progenitor cells.