-
公开(公告)号：US20150258250A1
公开(公告)日：2015-09-17
申请号：US14714685
申请日：2015-05-18
发明人： Keith A. Knisley , Vishnu T. Marla , Rachel Radspinner , Paul A. Silvagni , Jason J. Strid , Michael J. Vonesh
CPC分类号： A61L31/06 , A61F2/0077 , A61F2/82 , A61F2002/009 , A61L31/048 , A61L31/10 , A61L31/146 , A61L31/16 , A61L33/007 , A61L33/064 , A61L2300/416 , A61L2300/42 , A61L2400/12 , A61L2400/18 , C08L27/12 , C08L27/18
摘要： The invention is an improved biocompatible surface for a variety of medical purposes. The biocompatible surface employs a unique tight microstructure that demonstrates enhanced cellular response in the body, particularly when placed in contact with blood. As a blood contact surface, the present invention can be beneficially employed in a wide variety of implantable devices and in many other devices and equipment that come in contact with blood.
摘要翻译： 本发明是用于各种医疗目的的改进的生物相容性表面。 生物相容性表面采用独特的紧密的微结构，显示出体内增强的细胞反应，特别是当与血液接触时。 作为血液接触表面，本发明可以有益地用于各种可植入装置以及与血液接触的许多其它装置和设备中。
-
2.发明申请Articles Including Expanded Polytetrafluoroethylene Membranes with Serpentine Fibrils and Having a Discontinuous Fluoropolymer Layer Thereon 审中-公开包括具有蛇纹石纤维的膨胀聚四氟乙烯膜并具有不连续的含氟聚合物层的制品公开(公告)号：US20150045873A1
公开(公告)日：2015-02-12
申请号：US14522788
申请日：2014-10-24
发明人： Larry J. Kovach , Rachel Radspinner
CPC分类号： A61L31/048 , A61F2/07 , A61F2/82 , A61F2002/075 , A61F2240/002 , A61L31/10 , A61L31/129 , A61L31/146 , B29C65/02 , B29C66/545 , B29K2055/00 , B29K2105/04 , B29K2105/08 , B29L2009/00 , B29L2031/753 , B32B1/08 , B32B5/10 , B32B27/322 , B32B37/06 , B32B38/1866 , B32B2305/02 , B32B2355/00 , B32B2535/00 , C09D127/18 , F21V33/0076 , Y10T156/1075 , Y10T428/24802 , Y10T428/2481 , C08L27/12 , C08L27/18
摘要： Articles comprising an expanded polytetrafluoroethylene membrane having serpentine fibrils and having a discontinuous coating of a fluoropolymer thereon are provided. The fluoropolymer may be located at least partially in the pores of the expanded fluoropolymer membrane. In exemplary embodiments, the fluoropolymer is fluorinated ethylene propylene. The application of a tensile force at least partially straightens the serpentine fibrils, thereby elongating the article. The expanded polytetrafluoroethylene membrane may include a microstructure of substantially only fibrils. The articles can be elongated to a predetermined point at which further elongation is inhibited by a dramatic increase in stiffness. In one embodiment, the articles are used to form a covered stent device that requires little force to distend in the radial direction to a first diameter but is highly resistant to further distension to a second diameter (stop point). A large increase in diameter can advantageously be achieved prior to reaching the stop point.
摘要翻译： 提供包含具有蛇纹状原纤维并且在其上具有氟聚合物的不连续涂层的膨胀聚四氟乙烯膜的制品。 氟聚合物可以至少部分地位于膨胀的含氟聚合物膜的孔中。 在示例性实施方案中，含氟聚合物是氟化乙烯丙烯。 拉伸力的施加至少部分地拉直蛇形原纤维，从而延长制品。 膨胀的聚四氟乙烯膜可以包括基本上只有原纤维的微结构。 制品可以伸长到预定的点，在该预定点处，由于刚度的急剧增加可以抑制进一步伸长。 在一个实施例中，制品用于形成覆盖的支架装置，其需要很小的力以沿径向方向扩张到第一直径，但是对第二直径（停止点）的进一步扩张具有很高的抵抗力。 在到达停止点之前可以有利地实现直径的大的增加。
-
公开(公告)号：US11678983B2
公开(公告)日：2023-06-20
申请号：US16710637
申请日：2019-12-11
发明人： Rachel Radspinner , Ian Smith , Patrick S. Young
IPC分类号： A61F2/24 , A61M60/178 , A61M60/861 , A61M60/237 , A61F2/00
CPC分类号： A61F2/2457 , A61M60/178 , A61M60/237 , A61M60/861 , A61F2002/0086 , A61F2220/0016 , A61F2220/0033 , A61F2230/0091 , A61M2205/04
摘要： Implantable devices may include a single, first component or a plurality of components such as first and second components, the second component being flexibly coupled to the first component. A socket extends over one or more of the component(s), the socket being configured to enhance the inter-component interaction and/or including one or more exposed surface(s) configured to exhibit one or more tiers of foreign body responses within a range of possible foreign body responses.
-
公开(公告)号：US10926064B2
公开(公告)日：2021-02-23
申请号：US15882163
申请日：2018-01-29
发明人： Edward H. Cully , Jeffrey B. Duncan , Douglas S. Paget , Rachel Radspinner , Edward E. Shaw , Michael J. Vonesh
摘要： Embodiments of the present disclosure comprise occlusion and drug delivery devices and methods. One aspect of the disclosure comprises a drug delivery device comprising an inner expansion member and an outer drug delivery component. Another aspect of the disclosure comprises bioabsorbable, lumen-occluding implants.
-
公开(公告)号：US20180154120A1
公开(公告)日：2018-06-07
申请号：US15882163
申请日：2018-01-29
发明人： Edward H. Cully , Jeffrey B. Duncan , Douglas S. Paget , Rachel Radspinner , Edward E. Shaw , Michael J. Vonesh
CPC分类号： A61M25/10 , A61B17/12022 , A61B17/12109 , A61B17/12131 , A61B17/1214 , A61B17/12145 , A61B17/12159 , A61B17/12181 , A61B2017/00004 , A61B2017/00778 , A61B2017/00884 , A61B2017/00893 , A61M5/00 , A61M2025/1004 , A61M2025/105 , A61M2025/1065
摘要： Embodiments of the present disclosure comprise occlusion and drug delivery devices and methods. One aspect of the disclosure comprises a drug delivery device comprising an inner expansion member and an outer drug delivery component. Another aspect of the disclosure comprises bioabsorbable, lumen-occluding implants.
-
公开(公告)号：US09987395B2
公开(公告)日：2018-06-05
申请号：US15341467
申请日：2016-11-02
发明人： Larry J Kovach , Rachel Radspinner
IPC分类号： A61F2/07 , A61F2/06 , C09D127/18 , A61L31/04 , B32B38/18 , A61F2/82 , F21V33/00 , A61L31/10 , A61L31/12 , A61L31/14 , B29C65/02 , B29C65/00 , B32B1/08 , B32B5/10 , B32B27/32 , B32B37/06 , B29K55/00 , B29K105/04 , B29K105/08 , B29L9/00 , B29L31/00
CPC分类号： A61L31/048 , A61F2/07 , A61F2/82 , A61F2002/075 , A61F2240/002 , A61L31/10 , A61L31/129 , A61L31/146 , B29C65/02 , B29C66/545 , B29K2055/00 , B29K2105/04 , B29K2105/08 , B29L2009/00 , B29L2031/753 , B32B1/08 , B32B5/10 , B32B27/322 , B32B37/06 , B32B38/1866 , B32B2305/02 , B32B2355/00 , B32B2535/00 , C09D127/18 , F21V33/0076 , Y10T156/1075 , Y10T428/24802 , Y10T428/2481 , C08L27/12 , C08L27/18
摘要： Articles comprising an expanded polytetrafluoroethylene membrane having serpentine fibrils and having a discontinuous coating of a fluoropolymer thereon are provided. The fluoropolymer may be located at least partially in the pores of the expanded fluoropolymer membrane. In exemplary embodiments, the fluoropolymer is fluorinated ethylene propylene. The application of a tensile force at least partially straightens the serpentine fibrils, thereby elongating the article. The expanded polytetrafluoroethylene membrane may include a microstructure of substantially only fibrils. The articles can be elongated to a predetermined point at which further elongation is inhibited by a dramatic increase in stiffness. In one embodiment, the articles are used to form a covered stent device that requires little force to distend in the radial direction to a first diameter but is highly resistant to further distension to a second diameter (stop point). A large increase in diameter can advantageously be achieved prior to reaching the stop point.
-
公开(公告)号：US09775933B2
公开(公告)日：2017-10-03
申请号：US13773937
申请日：2013-02-22
发明人： Keith A. Knisley , Vishnu T. Marla , Rachel Radspinner , Paul A. Silvagni , Jason J. Strid , Michael J. Vonesh
IPC分类号： A61F2/82 , A61L31/06 , A61L31/04 , A61L31/10 , A61L31/14 , A61L31/16 , A61L33/00 , A61L33/06 , A61F2/00
CPC分类号： A61L31/06 , A61F2/0077 , A61F2/82 , A61F2002/009 , A61L31/048 , A61L31/10 , A61L31/146 , A61L31/16 , A61L33/007 , A61L33/064 , A61L2300/416 , A61L2300/42 , A61L2400/12 , A61L2400/18 , C08L27/12 , C08L27/18
摘要： The invention is an improved biocompatible surface for a variety of medical purposes. The biocompatible surface employs a unique tight microstructure that demonstrates enhanced cellular response in the body, particularly when placed in contact with blood. As a blood contact surface, the present invention can be beneficially employed in a wide variety of implantable devices and in many other devices and equipment that come in contact with blood.
-
8.发明申请公开(公告)号：US20130203874A1
公开(公告)日：2013-08-08
申请号：US13826590
申请日：2013-03-14
发明人： Ping Xu , Jack J. Hegenbarth , Rachel Radspinner , Paul D. Drumheller , William B. Johnson , Wen Liu , Xin Kang Chen
IPC分类号： C08F214/26
CPC分类号： A61L31/041 , A61L31/048 , A61L31/16 , B01D67/0093 , B01D71/32 , B01J39/18 , B29C55/005 , B29K2027/18 , B29K2105/04 , B29K2995/0092 , C08F14/26 , C08F214/26 , C08F214/262 , C08F214/265 , C08F220/28 , C08F220/50 , C08F228/02 , C08J5/2237 , C08J9/28 , C08J9/35 , C08J2201/0502 , C08J2327/18 , C08L27/18 , C08L2205/02 , Y10T428/31544 , C08L2666/04 , C08F2/22
摘要： A functional TFE copolymer fine powder is described, wherein the TFE copolymer is a polymer of TFE and at least one functional comonomer, and wherein the TFE copolymer has functional groups that are pendant to the polymer chain. The functional TFE copolymer fine powder resin is paste extrudable and expandable. Methods for making the functional TFE copolymer are also described. The expanded functional TFE copolymer material may be post-reacted after expansion.
-
公开(公告)号：US11865276B2
公开(公告)日：2024-01-09
申请号：US17160838
申请日：2021-01-28
发明人： Edward H. Cully , Jeffrey B. Duncan , Douglas S. Paget , Rachel Radspinner , Edward E. Shaw , Michael J. Vonesh
CPC分类号： A61M25/10 , A61B17/12022 , A61B17/12109 , A61B17/12131 , A61M5/00 , A61B17/1214 , A61B17/12145 , A61B17/12159 , A61B17/12181 , A61B2017/00004 , A61B2017/00778 , A61B2017/00884 , A61B2017/00893 , A61M2025/1004 , A61M2025/105 , A61M2025/1065
摘要： Embodiments of the present disclosure comprise occlusion and drug delivery devices and methods. One aspect of the disclosure comprises a drug delivery device comprising an inner expansion member and an outer drug delivery component. Another aspect of the disclosure comprises bioabsorbable, lumen-occluding implants.
-
公开(公告)号：US11844514B2
公开(公告)日：2023-12-19
申请号：US17403038
申请日：2021-08-16
IPC分类号： A61B17/06 , A61B17/04 , A61F2/24 , A61L17/14 , C08F114/26 , C08F214/26 , C08F216/14 , A61F2/00 , A61B17/00
CPC分类号： A61B17/06166 , A61B17/0469 , A61F2/2457 , A61L17/145 , C08F114/26 , C08F214/262 , C08F216/1408 , A61B2017/00862 , A61B2017/0619 , A61B2017/06057 , A61B2017/06171 , A61B2017/06176 , A61F2/2466 , A61F2002/0081 , A61F2210/0076 , A61F2250/0024 , A61L2400/02 , C08F2800/20
摘要： Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that include a cord that is flexible and elongated defining a length. The cord may include a core having a porous surface and a porosity-reducing element on at least a portion of the core.
-
-
-
-
-
-
-
-
-
搜索结果
33 条记录 (耗时 0.018 秒)
