公开(公告)号：WO2004075601A1

公开(公告)日：2004-09-02

申请号：PCT/GB2004/000750

申请日：2004-02-24

Applicant: 1...LIMITED ,  HOOLEY, Anthony ,  LENEL, Ursula, Ruth ,  GOUDIE, Angus, Gavin ,  SHEPHERD, Mark, Richard ,  BIENEK, Irving, Alexander

Inventor： HOOLEY, Anthony ,  LENEL, Ursula, Ruth ,  GOUDIE, Angus, Gavin ,  SHEPHERD, Mark, Richard ,  BIENEK, Irving, Alexander

IPC: H04R1/40

CPC classification number: H04R3/12 ,  H04N5/45 ,  H04N5/642 ,  H04R1/403 ,  H04R5/02 ,  H04R2201/401 ,  H04R2201/403 ,  H04R2201/405 ,  H04R2203/12 ,  H04R2205/022 ,  H04R2217/03 ,  H04R2499/15

Abstract: A loudspeaker system is described including an array of electro-acoustic transducers capable of generating steerable beams of sound and additional transducers adapted to reproduce low frequency sound being placed at the perimeter of said array.

Abstract translation: 描述了一种扬声器系统，其包括能够产生可转向的声束的电声换能器的阵列，以及适于再现放置在所述阵列的周边的低频声音的附加换能器。

公开(公告)号：WO2004045945A1

公开(公告)日：2004-06-03

申请号：PCT/GB2003/003482

申请日：2003-08-08

Applicant: PETORLEO BRASILEIRO SA - PETROBRAS ,  BENSON, John, Everett

Inventor： KOMURA, Adolfo, Tsuyoshi ,  SINQUINI, Jose, Celio ,  CAPLLONCH, Ricardo, Wagner ,  MACHADO, Rogerio, Diniz

IPC: B63B21/50

CPC classification number: B63B21/50 ,  B63B21/20

Abstract: The invention is comprised of a Quick Anchoring Equipment system (30) which permits underwater connection and disconnection of anchoring lines (2) to anchoring devices that are already fixedly attached to the bottom of the sea. The Quick Anchoring Equipment (30) consists of chain cable, cables, hooks and buoys specifically organized and configured, which, are attached at the submerged end of the anchoring line (2), which makes it possible with a single support boat (5), together with a remote operated vehicle (6), to carry out this whole anchoring lines (2) operation fundamental to floating platforms (1). The invention also includes the method to install and uninstall the Quick Anchoring Equipment (30).

Abstract translation: 本发明包括一种快速锚固设备系统（30），其允许锚固线（2）水下连接和断开到已经固定地附接到海底的锚定装置。 快速锚固设备（30）由链式电缆，电缆，钩和浮标组成，具体组织和构造，连接在锚定线（2）的浸没端，可以用单个支撑船（5） 与远程操作车辆（6）一起执行对浮动平台（1）的基本操作的整个锚定线（2）。 本发明还包括安装和卸载快速锚定设备的方法（30）。

公开(公告)号：WO2003041566A3

公开(公告)日：2003-05-22

申请号：PCT/US2002/036719

申请日：2002-11-14

Applicant: UNIVERSITY OF BRITISH COLUMBIA ,  ILLSLEY, Scott, G. ,  HODGSON, Antony, J.

Inventor： ILLSLEY, Scott, G. ,  HODGSON, Antony, J.

IPC: A61B19/00

Abstract: Methods and systems are described to quantitatively determine the degree of soft tissue constraints on knee ligaments and for properly determining placement parameters for prosthetic components in knee replacement surgery that will minimize strain on the ligaments. In one aspect, a passive kinetic manipulation technique is used in conjunction with a computer aided surgery (CAS) system to accurately and precisely determine the length and attachment sites of ligaments. These manipulations are performed after an initial tibial cut and prior to any other cuts or to placement of any prosthetic component. In a second aspect, a mathematical model of knee kinematics is used with the CAS system to determine optimal placement parameters for the femoral and tibial components of the prosthetic device that minimizes strain on the ligaments.

公开(公告)号：WO2022173704A2

公开(公告)日：2022-08-18

申请号：PCT/US2022/015514

申请日：2022-02-07

Applicant: ARCHER-DANIELS-MIDLAND COMPANY

Inventor： VENKITASUBRAMANIAN, Padmesh ,  GARNER, Ashley ,  ISLAM, S M Mahfuzul ,  SUBEDI, Bishnu ,  WELCH, Mark ,  GOVINDARAJAN, Sridhar

IPC: C12N9/24 ,  C13K1/06

Abstract: This disclosure provides maltotriose amylase enzymes useful for commercial scale production of reduced sugar glucose syrups (RSGS) from a starch. Useful enzymes ("amylase variants" or "enzyme variants") may be variants of a Bacillus subtilis amylase or enzymes with at least 90 % sequence identity thereto engineered with mutations that improve thermal tolerance and activity at a temperature above 50⁰C as compared with the parent enzymes.

公开(公告)号：WO2015156802A1

公开(公告)日：2015-10-15

申请号：PCT/US2014/033580

申请日：2014-04-10

Applicant: ARCHER DANIELS MIDLAND COMPANY

Inventor： STENSRUD, Kenneth ,  MA, Chi-Cheng

IPC: A23L1/236 ,  B01J23/72 ,  C07G3/00

CPC classification number: C07D307/12 ,  A23L27/34 ,  A23V2002/00 ,  B01J23/72 ,  B01J25/00 ,  C07C29/132 ,  C07C29/60 ,  C07D307/20 ,  C07D493/04 ,  C07G3/00 ,  C07C31/24 ,  C07C31/22 ,  C07C31/26

Abstract: Disclosed herein are methods for synthesizing 1,2,5,6-hexanetetrol (HTO), 1,6 hexanediol (HDO) and other reduced polyols from C5 and C6 sugar alcohols or R glycosides. The methods include contacting the sugar alcohol or R-glycoside with a copper catalyst, most desirably a Raney copper catalyst with hydrogen for a time, temperature and pressure sufficient to form reduced polyols having 2 to 3 fewer hydoxy groups than the starting material. When the starting compound is a C6 sugar alcohol such as sorbitol or R-glycoside of a C6 sugar such as methyl glucoside, the predominant product is HTO. The same catalyst can be used to further reduce the HTO to HDO.

Abstract translation: 本文公开了用于从C5和C6糖醇或R糖苷合成1,2,5,6-己烷乙醇（HTO），1,6-己二醇（HDO）和其它还原的多元醇的方法。 所述方法包括使糖醇或R-糖苷与铜催化剂接触，最理想的是具有氢气的拉尼铜催化剂一段时间，足以形成比起始原料少2-3个羟基的还原多元醇的温度和压力。 当起始化合物是C6糖醇如C6糖如山梨糖醇或R-糖苷如甲基葡糖苷时，主要产物是HTO。 可以使用相同的催化剂进一步将HTO还原成HDO。

公开(公告)号：WO2013173134A1

公开(公告)日：2013-11-21

申请号：PCT/US2013/040023

申请日：2013-05-08

Applicant: ARCHER DANIELS MIDLAND COMPANY

Inventor： BINDER, Thomas, P.

IPC: A23D9/04

CPC classification number: C08B30/044 ,  A23D9/02 ,  C11B1/10 ,  C11B3/008

Abstract: Anhydrous methods of fractionating corn grain that do not require the use of water but rather depends on use of organic solvents are described. The methods include contacting whole grain corn flour with a at least one organic solvent selected from the group consisting of a C1-C6 alcohol, ketone, ester or furan to form an admixture having no more than 15% w/w water. The admixture is separated into i) a solids fraction enriched with corn fiber and protein and 2) a liquid organic slurry comprising suspended starch, dissolved corn oil and the organic solvent. The starch is separated from the first organic slurry to obtain a solvent extracted solid starch fraction and a clarified organic solution. The clarified organic solution which contains dissolved oils is retained and may be evaporated to obtain corn oil that can be further refined.

Abstract translation: 描述了不需要使用水分离谷物的无水方法，而取决于有机溶剂的使用。 所述方法包括使全谷物玉米粉与至少一种选自C1-C6醇，酮，酯或呋喃的有机溶剂接触，形成不超过15％w / w水的混合物。 将混合物分离为i）富含玉米纤维和蛋白质的固体级分，以及2）包含悬浮淀粉，溶解的玉米油和有机溶剂的液体有机浆料。 将淀粉与第一有机浆料分离，得到溶剂萃取的固体淀粉部分和澄清的有机溶液。 含有溶解油的澄清有机溶液被保留并且可以被蒸发以获得可进一步精制的玉米油。

公开(公告)号：WO2013166405A2

公开(公告)日：2013-11-07

申请号：PCT/US2013/039496

申请日：2013-05-03

Applicant: ARCHER DANIELS MIDLAND COMPANY

Inventor： ABBAS, Charles ,  BAO, Wu-Li

IPC: C12P7/06

CPC classification number: C12P7/14 ,  C12N9/2434 ,  C12P7/06 ,  C12P7/10 ,  C12P19/02 ,  C12P19/14 ,  Y02E50/16 ,  Y02E50/17 ,  Y02P20/52

Abstract: A method to increase ethanol production from a corn dry-mill process is described that comprises adding an enzyme preparation derived from Trichoderma reesei having cellulolytic activity to a saccharification process that includes conventional alpha amylase and glucoamylase. The addition of the cellulolytic enzyme decreases viscosity of the saccharified mash and can increase ethanol yield from a dry grind fermentation by as much as 10% or more. Specific characteristics are provided to show surprising and advantageous results of one particular preparation of cellulolytic enzymes from T. reesei.

Abstract translation: 描述了从玉米干磨法生产乙醇生产的方法，其包括将含有纤维素分解活性的里氏木霉的酶制剂添加到包含常规α-淀粉酶和葡糖淀粉酶的糖化过程中。 纤维素分解酶的添加降低了糖化的糊状物的粘度，并且可以将来自干研磨发酵的乙醇产量提高多达10％或更多。 提供具体特征以显示来自里氏木霉的纤维素分解酶的一种特殊制备的惊人和有利的结果。

公开(公告)号：WO2012032340A1

公开(公告)日：2012-03-15

申请号：PCT/GB2011/051664

申请日：2011-09-06

Applicant: ST GEORGE'S HOSPITAL MEDICAL SCHOOL ,  ANTONIOS, Tarek Francis

Inventor： ANTONIOS, Tarek Francis

IPC: A61B3/12 ,  A61B5/026 ,  A61B5/02

CPC classification number: A61B5/0261 ,  A61B1/00149 ,  A61B1/24 ,  A61B3/1241 ,  A61B3/13 ,  A61B3/152 ,  A61B5/02007 ,  A61B5/4839 ,  A61B5/6835

Abstract: The invention relates to methods and apparatuses for positioning a probe for observing microcirculation vessels, in particular the microcirculation vessels in mucous membranes. In one aspect, the apparatus comprises a mechanical arm and a micropositioner for positioning the probe, thereby allowing fine control of the probe's position.

Abstract translation: 本发明涉及用于定位用于观察微循环血管，特别是粘膜中的微循环血管的探针的方法和装置。 在一个方面，该装置包括用于定位探针的机械臂和微定位器，从而允许精确控制探头的位置。

公开(公告)号：WO2012015616A1

公开(公告)日：2012-02-02

申请号：PCT/US2011/044324

申请日：2011-07-18

Applicant: ARCHER DANIELS MIDLAND COMPANY ,  HOWARD, Stephen J. ,  SANBORN, Alexandra J.

Inventor： HOWARD, Stephen J. ,  SANBORN, Alexandra J.

IPC: C07C51/00 ,  C07D307/02

CPC classification number: C07D307/93 ,  C07C51/00 ,  C07C59/185 ,  C07C67/00 ,  C07D307/46 ,  C07D307/48 ,  C07D307/50 ,  C07D493/04 ,  C07C69/716

Abstract: Methods for the production of dehydrated sugars and derivatives of dehydrated sugars using microwave (MW) irradiation and methods of purifying the same are described. The dehydrated sugars derivatives include 5-hydroxymethyl-2-furfural (HMF) and anhydrosugar alcohols such as sorbitans and isosorbide. The derivatives include HMF ethers, levulinic acid esters, and ether derivatives of the anhydrosugar alcohols. The described methods require lower reaction temperatures and shorter reaction times than similar non microwave mediated reactions known in the art. Typical reaction conditions are 120-210C, and typical reaction times are 30 minutes or less.

Abstract translation: 描述了使用微波（MW）照射制备脱水糖和脱水糖衍生物的方法及其纯化方法。 脱水糖衍生物包括5-羟甲基-2-糠醛（HMF）和脱水糖醇如脱水山梨醇和异山梨醇。 衍生物包括无水葡萄糖醇的HMF醚，乙酰丙酸酯和醚衍生物。 所描述的方法需要比本领域已知的类似的非微波介导的反应更低的反应温度和更短的反应时间。 典型的反应条件为120-210℃，典型的反应时间为30分钟或更短。

公开(公告)号：WO2011160170A1

公开(公告)日：2011-12-29

申请号：PCT/AU2011/000752

申请日：2011-06-21

Applicant: PETER MACCALLUM CANCER INSTITUTE ,  HSU, Andy Kang-Wei ,  SHORTT, Jake ,  NEESON, Paul ,  JOHNSTONE, Ricky, Wayne ,  RITCHIE, David

Inventor： HSU, Andy Kang-Wei ,  SHORTT, Jake ,  NEESON, Paul ,  JOHNSTONE, Ricky, Wayne ,  RITCHIE, David

IPC: A61K31/4015 ,  A61K47/22 ,  A61P31/00 ,  A61P33/00 ,  A61P35/00 ,  A61P37/02

CPC classification number: A61K31/4015

Abstract: Methods of treatment or prevention of a cancerous or pre-cancerous condition, of slowing or preventing growth of a cancerous condition, of stimulating a cell-mediated immune response, stimulating a Th1 helper T cell response against a pathogen in a mammal and of treating or preventing inflammatory diseases or disorders that involve administration of N-methyl pyrrolidone (NMP) or a physiologically acceptable salt, solvate, tautomer or prodrug thereof are provided. Also provided are formulations of an active agent.

Abstract translation: 治疗或预防癌症或癌前病症的方法，减缓或预防癌症状况的生长，刺激细胞介导的免疫应答，刺激针对哺乳动物的病原体的Th1辅助T细胞应答以及治疗或 提供了预防涉及N-甲基吡咯烷酮（NMP）或其生理上可接受的盐，溶剂化物，互变异构体或前药的施用的炎性疾病或病症。 还提供了活性剂的制剂。