公开(公告)号：WO2016029974A1

公开(公告)日：2016-03-03

申请号：PCT/EP2014/068438

申请日：2014-08-29

Applicant: NEC EUROPE LTD.

Inventor： YOUSAF, Faqir Zarrar

IPC: G06F9/50

CPC classification number: H04L47/781 ,  G06F9/5077 ,  G06F9/5083 ,  G06F2209/506 ,  G06F2209/508 ,  H04L41/5025 ,  H04L47/70 ,  H04L47/783 ,  H04L47/805

Abstract: The present invention relates to a method for operating a virtual network infrastructure, preferably in form of a software-defined network, a cloud infrastructure and/or a data center, wherein the physical infrastructure comprises one or more resources, comprising the steps of a) Monitoring utilization levels of one or more resource units of said resources for virtual resources requesting said resource units, b) Calculating average absolute resource utilization values based on said utilization levels for each virtual resource, c) Calculating a reference resource affinity score - RRAS - for each resource unit, wherein said RRAS indicates at least how much the utilization of a reference resource unit impacts the utilization of other resource units on a resources, using said average absolute resource utilization values, d) Assigning of resources by an entity, preferably a virtual infrastructure controller - VIC - and/or a VIC-agent on a resource, based on said RRAS for virtual resources.

Abstract translation: 本发明涉及一种用于操作虚拟网络基础设施的方法，优选地以软件定义的网络，云基础设施和/或数据中心的形式，其中所述物理基础设施包括一个或多个资源，其包括以下步骤：a） 监测用于请求所述资源单元的虚拟资源的所述资源的一个或多个资源单元的利用水平，b）基于每个虚拟资源的所述利用水平来计算平均绝对资源利用率值，c）计算参考资源相关性得分 - RRAS 每个资源单元，其中所述RRAS至少使用所述平均绝对资源利用值来指示参考资源单元的利用率对资源的其他资源单元的利用影响多少，d）由实体分配资源，优选虚拟 基础设施控制器 - VIC - 和/或资源上的VIC代理，基于所述虚拟资源的RRAS。

公开(公告)号：WO2016008519A1

公开(公告)日：2016-01-21

申请号：PCT/EP2014/065255

申请日：2014-07-16

Applicant: NEC EUROPE LTD.

Inventor： YOUSAF, Faqir Zarrar ,  MAEDER, Andreas

IPC: H04L12/801 ,  H04L12/815 ,  H04L12/823

CPC classification number: H04L47/115 ,  H04L47/28 ,  H04L47/32

Abstract: The present invention relates to a method for managing data flows in a network with a plurality of forwarding elements routing flows between network entities (UD, N, SN, FE) of a network or network domain (ND), wherein a) flows between network entities are marked with congestion information, preferably in form of resource utilization information, by at least one of the forwarding elements such that the highest congestion level prevailing on the respective flow path is indicated, b) the locations of one or more possible and/or present bottlenecks and/or congestions in the network based on the congestion information are identified, and c) one or more actions are performed to avoid, mitigate, and/or to resolve the identified possible and/or present bottlenecks and/or congestions.

Abstract translation: 本发明涉及一种用于管理具有多个转发元件的网络中的数据流的方法，所述多个转发元件在网络或网络域（ND）的网络实体（UD，N，SN，FE）之间路由流，其中a）在网络 实体通过至少一个转发元件标记为优先以资源利用信息的形式的拥塞信息，使得指示在相应流路上流行的最高拥塞水平，b）一个或多个可能和/或可能的位置， 识别基于拥塞信息的网络中的目前的瓶颈和/或拥塞，以及c）执行一个或多个动作以避免，减轻和/或解决所识别的可能和/或目前的瓶颈和/或拥塞。

公开(公告)号：WO2015192892A1

公开(公告)日：2015-12-23

申请号：PCT/EP2014/062725

申请日：2014-06-17

Applicant: NEC EUROPE LTD.

Inventor： KLAEDTKE, Felix ,  KARAME, Ghassan ,  BIFULCO, Roberto

IPC: H04L12/24

CPC classification number: H04L41/06 ,  H04L47/2483 ,  H04L69/22

Abstract: A method of providing access control for a software defined network (SDN) controller, wherein said controller (4), upon receiving a trigger event from the data plane (1) of said software defined network, triggers one or more applications (6) that are installed to run at the control plane (2) of said software defined network atop said controller (4) to react to said trigger event, is characterized in that said controller (4), before triggering applications (6) due to a trigger event, applies a conflict resolution scheme comprising the steps of defining flow spaces on the basis of packet headers and assigning each flow space a priority, determining all flow spaces that are affected by said trigger event and selecting from these flow spaces a single flow space having assigned a priority that complies with a predetermined policy, and determining, from the applications related to said selected flow space, a single application – master application – according to predefined criteria and triggering, in addition to said master application, only those applications whose reactions to said trigger event do not conflict with said master application. Furthermore, a corresponding software defined network (SDN) with access control and a corresponding SDN controller are disclosed.

Abstract translation: 一种为软件定义网络（SDN）控制器提供访问控制的方法，其中所述控制器（4）在从所述软件定义的网络的数据平面（1）接收到触发事件时触发一个或多个应用（6） 被安装为在所述控制器（4）顶部的所述软件定义网络的控制平面（2）下运行以对所述触发事件作出反应，其特征在于，所述控制器（4）在触发应用（6）之前由于触发事件 ，应用冲突解决方案，其包括以下步骤：基于分组报头来定义流动空间，并且将每个流动空间分配给优先级，确定受所述触发事件影响的所有流动空间，并从这些流动空间中选择具有分配的单个流动空间 符合预定策略的优先级，以及根据预定义的标准确定来自与所选流程空间相关的应用程序单个应用程序 - 主应用程序 除了所述主应用程序之外，只有那些对所述触发事件的反应不与所述主应用程序冲突的应用程序。 此外，公开了具有访问控制的相应的软件定义网络（SDN）和相应的SDN控制器。

公开(公告)号：WO2015189356A1

公开(公告)日：2015-12-17

申请号：PCT/EP2015/063107

申请日：2015-06-11

Applicant: POLYBIOCEPT AB

Inventor： MAEURER, Markus

IPC: A61K38/20 ,  A61K38/21 ,  A61K39/00 ,  A61K35/14 ,  A61K35/26 ,  C12N5/07 ,  G01N33/50 ,  A61P35/00 ,  A61P37/00 ,  A61P31/00

CPC classification number: C12N5/0636 ,  A61K35/14 ,  A61K35/17 ,  A61K35/26 ,  A61K38/20 ,  A61K38/21 ,  A61K39/0011 ,  A61K2035/124 ,  C12N2501/2302 ,  C12N2501/2315 ,  C12N2501/2321 ,  C12N2501/515 ,  G01N33/5047 ,  G01N2333/54 ,  G01N2333/55

Abstract: The present invention relates to a composition for expanding lymphocytes comprising at least two types of cytokines selected from interleukin 2 (IL-2), interleukin 15 (IL-15) and interleukin 21 (IL-21). It further relates to a Method of preparing a population of clinically relevant lymphocytes, comprising the steps of: obtaining a body sample from a mammal in particular a tissue sample or body liquid sample, comprising at least one lymphocyte and optionally separating the cells in the body sample, culturing the body sample in-vitro to expand and/or stimulate lymphocytes in the sample wherein the culturing comprises using IL-2, IL-15 and/or IL-21, and optionally determining the presence of clinically relevant lymphocyte in the cultured sample. The present invention also relates to an immunotherapy and the population of clinically relevant lymphocytes.

Abstract translation: 本发明涉及包含选自白介素2（IL-2），白细胞介素15（IL-15）和白细胞介素21（IL-21））中的至少两种细胞因子的淋巴细胞扩增用组合物。 它进一步涉及一种制备临床相关淋巴细胞群体的方法，其包括以下步骤：从哺乳动物，特别是组织样品或体液样品获得身体样品，其包含至少一种淋巴细胞，并任选分离体内的细胞 样品，体外培养身体样品以扩增和/或刺激样品中的淋巴细胞，其中培养包括使用IL-2，IL-15和/或IL-21，并任选地确定培养物中临床相关淋巴细胞的存在 样品。 本发明还涉及免疫治疗和临床相关淋巴细胞群体。

公开(公告)号：WO2015189301A1

公开(公告)日：2015-12-17

申请号：PCT/EP2015/062992

申请日：2015-06-10

Applicant: POLYBIOCEPT AB

Inventor： GEYER, Jakob ,  MAEURER, Markus ,  DODOO, Ernest

IPC: C12N5/0787 ,  C12N5/0786

CPC classification number: C12N5/0634 ,  C12N5/0636 ,  C12N5/0642 ,  C12N5/0645 ,  C12N2500/32 ,  C12N2500/34 ,  C12N2500/36 ,  C12N2501/105 ,  C12N2501/11 ,  C12N2501/115 ,  C12N2501/135 ,  C12N2501/20 ,  C12N2501/2302 ,  C12N2501/2306 ,  C12N2501/2315 ,  C12N2501/2321 ,  C12N2501/25 ,  C12N2501/33 ,  C12N2501/375 ,  C12N2501/39 ,  C12N2501/392 ,  C12N2501/998

Abstract: The present invention provides a method for preparing a cell culture medium comprising a mixture of blood products from two or more donors, comprising the steps of: a) providing at least a first blood product from a first donor; b) measuring the concentration of at least one quality factor in the first blood product; c) comparing the measured concentration of a quality factor to a concentration range predefined for the quality factor; d) selecting the first blood product for the cell culture medium if the concentration measured for the quality factor is in the predefined range and optionally converting the first selected blood product into a first processed blood product or else unselecting the first blood product.

Abstract translation: 本发明提供了一种制备细胞培养基的方法，所述方法包括来自两种或更多种供体的血液制品的混合物，其包括以下步骤：a）至少提供来自第一供体的第一血液制品; b）测量第一血液制品中至少一个品质因子的浓度; c）将质量因子的测量浓度与为品质因数预定的浓度范围进行比较; d）如果为质量因子测量的浓度在预定范围内，并且可选择地将第一选定的血液制品转化为第一加工血液制品或者取消选择第一血液制品，则选择细胞培养基的第一血液制品。

公开(公告)号：WO2015173434A1

公开(公告)日：2015-11-19

申请号：PCT/EP2015/060917

申请日：2015-05-18

Applicant: NEC EUROPE LTD. ,  UNIVERSITÄT MANNHEIM

Inventor： ARMKNECHT, Frederik ,  BOHLI, Jens-Matthias ,  KARAME, Ghassan ,  REUTER, Christian

IPC: G06F21/64 ,  H04L29/06 ,  G06F3/06

CPC classification number: H04L63/10 ,  G06F3/067 ,  G06F21/645 ,  G06F2221/2101 ,  G06F2221/2115 ,  H04L63/123

Abstract: The present invention relates to a method for proving retrievability, 'POR', of information, said method being performed in a memory available to one or more computation devices, wherein credentials between a user device, a storing device and an auditing device between each pair of said devices are exchanged and used for communication between them, comprising the steps of a) Encoding the information to be stored on said storing device by said user device or said auditing device, b) Storing the encoded information on said storing device, c) Verifying the correctness of said stored information by the auditing device and using unpredictable random information d) Transmitting correctness information to the user device, said correctness information being secure and which are generated based on the result of said verification by the auditing device and e) Validating said correctness information by the user device for proving retrievability of said stored information and said unpredictable random information.

Abstract translation: 本发明涉及一种用于证明信息的可检索性“POR”的方法，所述方法在可用于一个或多个计算设备的存储器中执行，其中用户设备，存储设备和每对之间的审核设备之间的凭证 所述设备被交换并用于它们之间的通信，包括以下步骤：a）由所述用户设备或所述审核设备对要存储在所述存储设备上的信息进行编码; b）将编码信息存储在所述存储设备上; c） 验证所述存储的信息由审核设备的正确性和使用不可预测的随机信息d）向用户设备发送正确性信息，所述正确性信息是安全的，并且基于审核设备的所述验证的结果生成，以及e）验证 所述用户设备的所述正确性信息用于证明所述存储的信息和所述不可预测的ra的可检索性 ndom信息。

公开(公告)号：WO2015155060A1

公开(公告)日：2015-10-15

申请号：PCT/EP2015/057004

申请日：2015-03-31

Applicant: STRELEC GMBH

Inventor： STREMMEL, Wolfgang

IPC: A23J7/00 ,  A61K8/55 ,  A61K47/48 ,  A61K31/00 ,  A61K31/575 ,  A61K31/661 ,  A61K31/6615 ,  A61P3/04 ,  A61P3/06

CPC classification number: A61K31/00 ,  A23J7/00 ,  A23L33/30 ,  A61K31/575 ,  A61K31/661 ,  A61K31/6615 ,  A61K47/543 ,  A61K47/554 ,  A61K2300/00

Abstract: The present invention relates to the field of medical or cosmetic weight management. In particular, the present invention provides compounds for inhibition of fat absorption. Said compounds are characterized as phospholipase A inhibitors. In particular, the PLA inhibitors of the invention can be lysophospholipid-conjugates. The compounds of the invention can be used for therapeutic and cosmetic body fat reduction in a subject. Therapeutic use of the inventive compounds can in particular include obesity treatment. The present invention also provides methods, compositions and kits for weight management.

Abstract translation: 本发明涉及医疗或化妆品重量管理领域。 特别地，本发明提供抑制脂肪吸收的化合物。 所述化合物的特征在于磷脂酶A抑制剂。 特别地，本发明的PLA抑制剂可以是溶血磷脂缀合物。 本发明的化合物可用于受试者的治疗和化妆品体内脂肪减少。 本发明化合物的治疗用途可特别包括肥胖症治疗。 本发明还提供了用于体重管理的方法，组合物和试剂盒。

公开(公告)号：WO2015154831A1

公开(公告)日：2015-10-15

申请号：PCT/EP2014/075260

申请日：2014-11-21

Applicant: NEC EUROPE LTD.

Inventor： MASLEKAR, Nitin ,  GKIOTSALITIS, Konstantinos

IPC: G06Q10/04 ,  G06Q10/08

CPC classification number: G06Q10/047 ,  G06Q10/08355

Abstract: A method of dynamic fleet routing, wherein said fleet includes a number of vehicles that perform delivery services, and wherein an initial delivery plan is generated based on a customer demand for deliveries, wherein said initial delivery plan specifies routes for said vehicles and schedules customers of the delivery services within the routes, is characterized in the steps of splitting the planning period of said initial delivery plan into a number of time slots, associating each of said time slots with a slot inconsistency factor depending on factors that contribute to dynamicity within the respective time slot, and based on said slot inconsistency factor, allotting to each of said time slots an individual slack time to accommodate any dynamic changes. Furthermore, the invention relates to a corresponding fleet management system.

Abstract translation: 一种动态车队路由的方法，其中所述车队包括执行传送服务的多个车辆，并且其中基于客户的交付需求生成初始传送计划，其中所述初始传送计划指定所述车辆的路线并且调度客户的 路线内的传送服务的特征在于将所述初始传送计划的规划周期分为多个时隙，将每个所述时隙与时隙不一致因子相关联，所述时隙不一致因素取决于在相应的时间段内有助于动态的因素 时隙，并且基于所述时隙不一致因素，将每个所述时隙分配给单独的松弛时间以适应任何动态变化。 此外，本发明涉及相应的车队管理系统。

公开(公告)号：WO2015149842A1

公开(公告)日：2015-10-08

申请号：PCT/EP2014/056473

申请日：2014-03-31

Applicant: NEC EUROPE LTD.

Inventor： SCHMIDT, Mischa ,  FLOECK, Martin

IPC: G05B23/02 ,  G05B17/02

CPC classification number: G05B23/0229 ,  G05B15/02 ,  G05B23/0221 ,  G05B23/0232 ,  G05B23/0235 ,  G05B23/024 ,  G05B23/0275 ,  G05B2219/2614 ,  G06Q10/06

Abstract: For facilitating the assessment of a building's performance and providing information for a suitable configuration for energy savings a method for monitoring a building management system, BMS, is claimed, wherein data points within an observation window are observed, further comprising the following steps: statistically analysing the observations by a statistical measure, to obtain statistical data or a statistical characteristic of the observations, and detecting a logical and/or physical misconfiguration and/or deterioration of the BMS or of a sensor, actuator or sub-system of the BMS and/or detecting a change to the core and/or shell of the building, based on a deviating of the obtained statistical data or statistical characteristic of the observations from an expected statistical characteristic or feature. Further, a system for monitoring a building management system is claimed, preferably for carrying out the above mentioned method.

Abstract translation: 为了便于评估建筑物的性能并提供用于节能的合适配置的信息，要求保护建筑物管理系统（BMS）的方法，其中观察观察窗内的数据点，还包括以下步骤：统计分析 通过统计测量的观察结果，以获得观察结果的统计数据或统计特征，以及检测BMS或BMS的传感器，致动器或子系统的逻辑和/或物理错误配置和/或劣化，和/ 或者基于所获得的统计数据或观察值的统计特征与期望的统计特征或特征的偏差来检测建筑物的核心和/或壳体的变化。 此外，要求保护用于监控建筑物管理系统的系统，优选地用于执行上述方法。

公开(公告)号：WO2015139780A1

公开(公告)日：2015-09-24

申请号：PCT/EP2014/055772

申请日：2014-03-21

Applicant: NEC EUROPE LTD.

Inventor： HILDMANN, Hanno ,  MARTIN LOPEZ, Miquel

IPC: G08B13/16 ,  G08B13/196 ,  G08B29/04

CPC classification number: G08B29/046 ,  G08B13/1672 ,  G08B13/196 ,  G08B13/19671 ,  G08B13/19695

Abstract: A method for verifying authenticity of a monitoring signal, wherein a multitude of actuators are employed to impact with individual signals on a physical environment, wherein said individual signals originating from said actuators are directed to said physical environment, wherein at least one sensor device observes said physical environment in such a way that said sensor device records the monitoring signal representing a combined impact of said individual signals on said physical environment, wherein said monitoring signal is compared with an expected signal in order to determine a degree of similarity between said monitoring signal and said expected signal, wherein said expected signal is computed on the basis of predetermined templates, wherein said templates are previously generated in a secret initialization procedure in such a way that the impact on said physical environment for each of said individual signals is separately recorded as template by said sensor device. Furthermore, a corresponding monitoring system is disclosed.

Abstract translation: 一种用于验证监测信号的真实性的方法，其中使用多个致动器来影响物理环境上的各个信号，其中源自所述致动器的所述单独信号被引导到所述物理环境，其中至少一个传感器装置观察所述 物理环境，使得所述传感器设备记录表示所述个体信号对所述物理环境的组合影响的监视信号，其中所述监测信号与预期信号进行比较，以便确定所述监测信号和 所述预期信号，其中基于预定模板来计算所述预期信号，其中所述模板先前以秘密初始化过程生成，使得对于每个所述单独信号对所述物理环境的影响被分别记录为模板 通过所述传感器装置。 此外，公开了相应的监视系统。