公开(公告)号：WO2006107961A2

公开(公告)日：2006-10-12

申请号：PCT/US2006012491

申请日：2006-04-05

Applicant: BIOSCALE INC ,  MASTERS BRETT P ,  MILLER MICHAEL F

Inventor： MASTERS BRETT P ,  MILLER MICHAEL F

IPC: H03H3/00 ,  H03H3/04 ,  H03H3/10 ,  H03H9/02

CPC classification number: G01N29/036 ,  G01N9/002 ,  G01N2291/0256

Abstract: Electrically responsive devices and methods for fabricating electrically responsive devices involves applying an electrically responsive material (e.g., an electroactive material) over at least a portion of a surface of a substrate material and applying an electrode material over at least a portion of a surface of the electrically responsive material. At least one region of the electrode material is selectively removed exposing the electrically responsive material. At least some of the electrically responsive material is selectively removed in a region corresponding to the at least one region of the electrode material.

Abstract translation: 用于制造电响应装置的电响应装置和方法包括在基底材料的表面的至少一部分上施加电响应材料（例如，电活性材料），并将电极材料施加到至少一部分表面上 电响应材料。 选择性地去除电极材料的至少一个区域，暴露出电响应材料。 在对应于电极材料的至少一个区域的区域中选择性地去除至少一些电响应材料。

公开(公告)号：WO2006099122A1

公开(公告)日：2006-09-21

申请号：PCT/US2006/008572

申请日：2006-03-10

Applicant: LABCYTE INC. ,  ELLSON, Richard, N. ,  MILLER, Michael, F. ,  BRAMWELL, Arlen, Mark

Inventor： ELLSON, Richard, N. ,  MILLER, Michael, F. ,  BRAMWELL, Arlen, Mark

IPC: B01L3/00

CPC classification number: B01L3/50853 ,  B01L2200/142 ,  B01L2300/041 ,  B01L2300/042 ,  B01L2300/047 ,  B01L2300/0829 ,  B01L2300/10

Abstract: Fluid containers are disclosed which have fluid reservoirs in their closures. These reservoirs are advantageous to hold sacrificial fluid which lessens the loss of the fluid of interest to the outside through evaporation. The reservoirs may have openings to the inside or outside of the container, or to both. Reservoirs with openings to the outside serve to reduce evaporative loss by raising the partial pressure of fluid in the vicinity of the contact between the closure and the remainder of the container. The reservoirs may be refÊllable without opening the container. In one embodiment a fluid reservoir allows the zone of contact between the closure and the remainder of the container to be immersed in fluid, so that gases seeking to escape the interior of the container must pass through fluid. In a further embodiment a closure for a container comprises at least two closure members. The relative position of the closure members with respect to each other is altered upon mating of the closure and container. The alteration of the relative position of the closure members may result in one or more of the members approaching the container more closely. The alteration may result in one or more of the members pressing against the container.

Abstract translation: 公开了在其封闭件中具有流体储存器的流体容器。 这些储存器有利于保持牺牲流体，其通过蒸发减少感兴趣的流体的损失。 储存器可以具有到容器的内部或外部的开口，或者具有到两者的开口。 具有向外部开口的容器用于通过提高封闭件和容器的其余部分之间的接触附近的流体的分压来减少蒸发损失。 储存器可以在不打开容器的情况下被重新装入。 在一个实施例中，流体储存器允许封闭件和容器的其余部分之间的接触区浸没在流体中，使得试图逃离容器内部的气体必须通过流体。 在另一实施例中，用于容器的封闭件包括至少两个闭合构件。 封闭件相对于彼此的相对位置在封盖和容器配合时被改变。 关闭构件的相对位置的改变可能导致一个或多个构件更接近容器。 改变可能导致一个或多个构件压靠容器。

公开(公告)号：WO2007021907A2

公开(公告)日：2007-02-22

申请号：PCT/US2006/031329

申请日：2006-08-10

Applicant: BIOSCALE, INC. ,  MASTERS, Brett, P. ,  MILLER, Michael, F.

Inventor： MASTERS, Brett, P. ,  MILLER, Michael, F.

IPC: G01N30/96

CPC classification number: G01N29/036 ,  B82Y15/00 ,  B82Y30/00 ,  G01N2291/0256 ,  G01N2291/0257

Abstract: A system having reduced gas interference that includes a fluid chamber and a resonant sensor device in fluid communication with a fluid in the fluid chamber. The system includes a fluid control device adapted to change at least one of the fluid flow or pressure within the fluid chamber to achieve substantial wetting of surfaces in proximity to the resonant sensor device. Fluid surfaces of the system can include a material to increase the wettability (e.g., hydrophilicity) of the fluid surfaces.

Abstract translation: 具有减小的气体干扰的系统，其包括与流体室中的流体流体连通的流体室和谐振传感器装置。 该系统包括流体控制装置，其适于改变流体室内的流体流动或压力中的至少一个，以实现靠近谐振传感器装置的表面的实质润湿。 系统的流体表面可以包括增加流体表面的润湿性（例如亲水性）的材料。

公开(公告)号：WO02052329A3

公开(公告)日：2002-09-06

申请号：PCT/US0149412

申请日：2001-12-19

Applicant: AXSUN TECH INC ,  ATIA WALID A ,  NAGLE STEVEN F ,  MILLER MICHAEL F

Inventor： ATIA WALID A ,  NAGLE STEVEN F ,  MILLER MICHAEL F

IPC: B81B3/00 ,  B81B7/02 ,  G01J3/26 ,  G02B26/00 ,  G02B26/02 ,  G02B26/08 ,  G02B7/188

CPC classification number: G02B26/02 ,  B81B7/02 ,  G01J3/26 ,  G02B26/001

Abstract: A MOEMS Fabry-Perot tunable filter 100 includes an optical membrane structure 150. Two electrostatic cavities 136, 138 are provided, one on either side of the membrane structure 150. As a result, electrostatic attractive forces can be exerted on the optical membrane to enable deflection in either direction, typically, along the optical axis 10. This is useful in calibrating the tunable filter during operation to a lambd° set point. It is also useful in controlling the membrane to avoid unstable operation and increasing a deflection range.

Abstract translation: MOEMS法布里 - 珀罗可调滤波器100包括光学膜结构150.设置两个静电空腔136,138，一个在膜结构150的两侧。结果，可以在光学膜上施加静电吸引力，以使得能够 通常沿着光轴10在任一方向上偏转。这在将操作期间的可调谐滤波器校准到羔羊设定点时是有用的。 它也可用于控制膜以避免不稳定的操作和增加偏转范围。

公开(公告)号：WO2009131883A2

公开(公告)日：2009-10-29

申请号：PCT/US2009/040716

申请日：2009-04-15

Applicant: BIOSCALE, INC. ,  FALB, Peter, W. ,  BRANCAZIO, David ,  FRANCE, Eric ,  MASTERS, Brett, P. ,  MILLER, Michael, F. ,  ORMSBY, Joshua, R. ,  SLOAN, Walker

Inventor： FALB, Peter, W. ,  BRANCAZIO, David ,  FRANCE, Eric ,  MASTERS, Brett, P. ,  MILLER, Michael, F. ,  ORMSBY, Joshua, R. ,  SLOAN, Walker

IPC: B01L3/00 ,  G01N35/00

CPC classification number: G01N35/00029 ,  B01L3/5025 ,  B01L3/502715 ,  B01L3/502738 ,  B01L2200/025 ,  B01L2200/16 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2400/0487 ,  B01L2400/0655 ,  G01N2035/00148 ,  Y10T29/49

Abstract: A system for processing analytes in samples includes an instrument and a cartridge. The cartridge includes fluid inputs, input and output valve assemblies, processing devices, fluid reservoirs, and channels for carrying samples from the fluid inputs to the fluid reservoirs. The valve assemblies include valves adapted to form a sealed fluid chamber in response to force applied by a movable head assembly of the instrument. Each fluid reservoir is adapted to mate and align with an air displacement pump interface member. A valve assembly includes a recess wall surrounding a recess and a valve assembly wall surrounding both the recess and the recess wall. The recess wall and the valve assembly walls are adapted to mate with and seal against a flexible sheet covering the recess, the recess wall, and the valve assembly wall. The cartridge and instrument include complementary features for finely and coarsely aligning instrument assemblies with portions of the cartridge.

Abstract translation: 用于处理样品中分析物的系统包括仪器和墨盒。 墨盒包括流体输入，输入和输出阀组件，处理装置，流体储存器和用于将样品从流体输入传送到流体储存器的通道。 阀组件包括适于响应由仪器的可移动头组件施加的力而形成密封流体室的阀。 每个流体储存器适于与排气泵接口构件配合和对准。 阀组件包括围绕凹部的凹陷壁和围绕凹部和凹陷壁的阀组件壁。 凹陷壁和阀组件壁适于与覆盖凹部，凹陷壁和阀组件壁的柔性薄片配合并密封。 墨盒和仪器包括用于精细和粗略地对准具有部分墨盒的仪器组件的互补特征。

公开(公告)号：WO2007127107A2

公开(公告)日：2007-11-08

申请号：PCT/US2007009399

申请日：2007-04-17

Applicant: BIOSCALE INC ,  BAKSHI SHIVALIK ,  MILLER MICHAEL F

Inventor： BAKSHI SHIVALIK ,  MILLER MICHAEL F

CPC classification number: B81B2201/0214 ,  B81B2207/115

Abstract: Microfabricated devices for operation in a fluid that include a substrate that has a first and second surface and a first electrode material layer located over the first surface of the substrate. The devices have a piezoelectric material layer located over the first electrode material layer and a second electrode material layer located over the piezoelectric material layer. The devices also include a layer of isolation material located over the second electrode material layer that at least one of chemically or electrically isolates a portion of the second electrode material layer from a fluid. Some devices include a layer of conductive material located over the layer of isolation material.

Abstract translation: 在包括具有第一和第二表面的基底和位于基底的第一表面上的第一电极材料层的流体中操作的微型装置。 这些器件具有位于第一电极材料层上方的压电材料层和位于压电材料层上方的第二电极材料层。 所述装置还包括位于所述第二电极材料层上方的隔离材料层，所述隔离材料层中的至少一个化学或电化学地将所述第二电极材料层的一部分与流体隔离。 一些设备包括位于隔离层上方的导电材料层。