公开(公告)号：WO2008150346A1

公开(公告)日：2008-12-11

申请号：PCT/US2008/006044

申请日：2008-05-09

Applicant: REX MEDICAL, L.P.

Inventor： MCGUCKIN, James, F. ,  SCHALLER, David, M. ,  BRESSLER, James, E.

IPC: A61B17/00

CPC classification number: A61B17/0057 ,  A61B17/12022 ,  A61B17/12122 ,  A61B17/12172 ,  A61B2017/00575 ,  A61B2017/00579 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/00632

Abstract: A device for closing the left atrial appendage of a patient comprising a retention member composed of a shape memory material and a mesh material supported by the retention member. The retention member has a first elongated configuration for delivery and a second expanded configuration for placement within the left atrial appendage. The mesh is configured to block blot clot migration from the appendage. In the second configuration the retention member moves toward a shape memory position. The retention member has a plurality of appendage wall engagement members to secure the retention member to the appendage.

Abstract translation: 一种用于关闭患者的左心耳的装置，包括由形状记忆材料和由所述保持构件支撑的网状材料构成的保持构件。 保持构件具有用于输送的第一细长构造和用于放置在左心耳内的第二扩张构造。 网格被配置为阻止印迹凝块从附属物迁移。 在第二构造中，保持构件向形状记忆位置移动。 保持构件具有多个附属壁接合构件以将保持构件固定到附件。

公开(公告)号：WO2008130750A1

公开(公告)日：2008-10-30

申请号：PCT/US2008/056779

申请日：2008-03-13

Applicant: MINOS MEDICAL ,  GASCHE, Christopher ,  BELL, Stephen Graham ,  NODA, Wayne A. ,  SHARP, Bradley J.

Inventor： GASCHE, Christopher ,  BELL, Stephen Graham ,  NODA, Wayne A. ,  SHARP, Bradley J.

IPC: A61B1/31

CPC classification number: A61B17/12013 ,  A61B1/00135 ,  A61B17/0057 ,  A61B17/0469 ,  A61B17/068 ,  A61B17/22031 ,  A61B17/32056 ,  A61B2017/00269 ,  A61B2017/00349 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00615 ,  A61B2017/00632 ,  A61B2017/00862 ,  A61B2017/0412 ,  A61B2017/0417 ,  A61B2017/0427 ,  A61B2017/0477 ,  A61B2017/12018 ,  A61B2017/306 ,  A61B2018/1407 ,  A61B2217/005 ,  A61B2217/007

Abstract: Systems and methods are disclosed for the inversion of gastro intestinal diverticula and repair of associated intestinal wall tissue by means of endoscopy through a natural orifice such as the mouth or anus without making incisions in the abdominal wall or opening the peritoneal cavity.

Abstract translation: 公开了用于胃肠憩室反转的系统和方法，并通过内窥镜检查通过诸如口或肛门的天然孔口修复相关的肠壁组织，而不会在腹壁中切开或打开腹膜腔。

公开(公告)号：WO2007021647A3

公开(公告)日：2008-10-02

申请号：PCT/US2006030745

申请日：2006-08-07

Applicant: CARDIOKINETIX INC ,  SHARKEY HUGH R ,  KHAIRKHAHAN ALEXANDER ,  NIKOLIC SERJAN D ,  RADOVANCEVIC BRANISLAV

Inventor： SHARKEY HUGH R ,  KHAIRKHAHAN ALEXANDER ,  NIKOLIC SERJAN D ,  RADOVANCEVIC BRANISLAV

IPC: A61F2/00 ,  A61B17/08 ,  A61F2/02 ,  A61F13/00

CPC classification number: A61B17/0057 ,  A61B17/12022 ,  A61B17/12122 ,  A61B17/12172 ,  A61B2017/00243 ,  A61B2017/00575 ,  A61B2017/00579 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/00615 ,  A61B2017/00632 ,  A61B2017/00867 ,  A61B2017/00898 ,  A61B2017/00942 ,  A61B2017/12095

Abstract: A method and device for the treatment of a patient with heart disease and particularly a heart chamber having a myocardial rupture or characteristics of an incipient myocardial rupture. The heart chamber is partitioned so as to isolate a non-productive portion having a rupture or a region of an incipient rupture from a productive portion. The heart chamber is preferably partitioned with a reinforced membrane which has a pressure receiving surface that defines part of the productive portion of the heart chamber. The peripheral base of the reinforced membrane may have an eccentric configuration.

Abstract translation: 用于治疗患有心脏病的患者，特别是具有心肌破裂或初始心肌破裂特征的心室的方法和装置。 将心脏腔室分隔开以分离具有破裂的非生产性部分或从生产部分开始的初始区域。 心室优选用加强膜分隔，该增强膜具有限定心室的生产部分的一部分的压力接收表面。 增强膜的周边基底可以具有偏心构造。

公开(公告)号：WO2008010792A1

公开(公告)日：2008-01-24

申请号：PCT/US2006/027817

申请日：2006-07-14

Applicant: VIJAY, Venkataramana

Inventor： VIJAY, Venkataramana

IPC: A61M25/10

CPC classification number: A61B17/0057 ,  A61B17/12022 ,  A61B17/12122 ,  A61B17/12136 ,  A61B17/12172 ,  A61B2017/00579 ,  A61B2017/00588 ,  A61B2017/00601 ,  A61B2017/00632 ,  A61B2017/12054 ,  A61B2017/12095 ,  A61F2/2481 ,  A61F2002/2484

Abstract: Methods for cardiac ventricular restoration include delivering an implantable expandable device (524) into the ventricle via a catheter. The expandable device (524) is anchored either to the wall (520) of the left ventricle or to the inter-ventricular septum and then expanded. When expanded, the device assumes a size and shape which fills the lower portion of the ventricular cavity restoring the normal volume and ellipsoid shape of the remaining portion of the cavity and favorably altering myocardial oxygen demand and wall stress.

Abstract translation: 用于心脏心室恢复的方法包括通过导管将可植入的可扩张装置（524）输送到心室中。 可扩张装置（524）被锚固到左心室的壁（520）或者室间隔，然后扩张。 当扩张时，该装置呈现一个尺寸和形状，其填充了心室腔的下部，从而恢复腔的剩余部分的正常体积和椭圆形状，有利地改变心肌需氧量和壁应力。

公开(公告)号：WO2007044536A3

公开(公告)日：2007-12-06

申请号：PCT/US2006039183

申请日：2006-10-06

Applicant: JAVOIS ALEX

Inventor： JAVOIS ALEX

IPC: A61M29/00

CPC classification number: A61B17/0057 ,  A61B17/12022 ,  A61B17/12122 ,  A61B17/12172 ,  A61B2017/00575 ,  A61B2017/00579 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/00615 ,  A61B2017/00632 ,  A61B2017/00867

Abstract: The present invention provides devices and methods for occluding the left atrial appendage. The device includes an easily deployed wire structure of shape memory material sized to be appropriate for use in a patient. The device may be manufactured in various sizes for use in various patients. The device has a sheet of material attached for eclipsing the opening of the left atrial appendage and means for secured attachment substantially within the left atrial appendage. The method includes deploying the device within the left atrial appendage, securely anchoring the device, and ensuring that a sheet of material eclipses the opening of the left atrial appendage. These features are incorporated into the improved devices and methods in order to more effectively aid in the prevention of clot formation and clot migration into or out of the left atrial appendage to greatly decrease the risk of stroke in patients with atrial fibrillation.

Abstract translation: 本发明提供了用于闭塞左心耳的装置和方法。 该装置包括形状记忆材料的易于展开的线结构，其大小适合用于患者。 该装置可以制造成各种尺寸以用于各种患者。 该装置具有用于遮蔽左心耳的开口的用于遮盖左心耳的基本上在左心耳内的用于固定附接的装置的材料片。 该方法包括将该装置配置在左心耳内，牢固地锚定该装置，并确保一片材料遮蔽左心耳的开口。 这些特征被结合到改进的装置和方法中，以便更有效地帮助防止凝块形成和凝块移入或移出左心耳，以大大降低心房颤动患者中风的风险。

公开(公告)号：WO2006044467A3

公开(公告)日：2007-08-30

申请号：PCT/US2005036690

申请日：2005-10-13

Applicant: CHF TECHNOLOGIES INC ,  CHIN SING-FATT ,  BERTOLERO ARTHUR ,  ANNEST LON

Inventor： CHIN SING-FATT ,  BERTOLERO ARTHUR ,  ANNEST LON

IPC: A61F2/00

CPC classification number: A61F2/2481 ,  A61B1/3137 ,  A61B5/042 ,  A61B8/12 ,  A61B17/0401 ,  A61B17/0469 ,  A61B2017/00022 ,  A61B2017/00044 ,  A61B2017/00106 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/00575 ,  A61B2017/00579 ,  A61B2017/00606 ,  A61B2017/00632 ,  A61B2017/0412 ,  A61B2017/0419 ,  A61B2017/0427 ,  A61B2017/0464 ,  A61B2017/306 ,  A61B2018/00392 ,  A61B2090/376 ,  A61B2090/3782 ,  A61F2/2487 ,  A61F2002/2484 ,  A61M25/09

Abstract: A method for reducing left ventricular volume, which comprises identifying infarcted tissue during open chest surgery; reducing left ventricle volume while preserving the ventricular apex; and realigning the ventricular apex, such that the realigning step comprises closing the lower or apical portion of said ventricle to achieve appropriate functional contractile geometry of said ventricle in a dyskinetic ventricle of a heart.

Abstract translation: 一种降低左心室容量的方法，其包括在开胸手术期间识别梗死组织; 减少左心室体积，同时保留心室顶点; 并且重新对准心室顶点，使得重新对准步骤包括关闭所述心室的下部或顶端部分，以在心脏的运动障碍心室中实现所述心室的适当的功能收缩几何形状。

公开(公告)号：WO2004103209A2

公开(公告)日：2004-12-02

申请号：PCT/US2004/015734

申请日：2004-05-19

Applicant: SECANT MEDICAL LLP ,  GREENHALGH, E., Skott ,  KLESHINSKI, Stephen, J.

Inventor： GREENHALGH, E., Skott ,  KLESHINSKI, Stephen, J.

IPC: A61F

CPC classification number: A61B17/0057 ,  A61B17/12022 ,  A61B17/12113 ,  A61B17/12122 ,  A61B17/12168 ,  A61B17/12172 ,  A61B2017/00575 ,  A61B2017/00579 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/00601 ,  A61B2017/00632 ,  A61B2017/00783 ,  A61B2017/00862 ,  A61B2017/4233 ,  A61F2/01 ,  A61F2/2445 ,  A61F2/2475 ,  A61F2002/018 ,  A61F2220/0016 ,  A61F2230/0006 ,  A61F2230/0067 ,  A61F2250/0039

Abstract: A device positionable in an opening in a flexible membrane or in the lumen of a vessel having a flexible sidewall. The device distends or biases opposite portions defining the opening or forming the vessel sidewall outwardly in the plane of the device. The outward biasing draws opposing portions of the opening or sidewall inwardly in a direction perpendicular to the plane of the device and into apposition or contact.

Abstract translation: 可定位在柔性膜的开口中或具有柔性侧壁的容器的内腔中的装置。 该装置膨胀或偏压限定开口的相对部分或在装置的平面中向外形成容器侧壁。 向外的偏置在垂直于装置的平面的方向上向内拉动开口或侧壁的相对部分，并且成一体或接触。

公开(公告)号：WO2002071977A2

公开(公告)日：2002-09-19

申请号：PCT/US2002/007009

申请日：2002-03-08

Applicant: ATRITECH, INC.

Inventor： SUTTON, Gregg, S. ,  PETERSON, Dean ,  WELCH, Jeffrey

IPC: A61F2/00

CPC classification number: A61B17/12045 ,  A61B17/12022 ,  A61B17/12122 ,  A61B17/12172 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/00615 ,  A61B2017/00632 ,  A61B2017/1205 ,  A61B2017/12059 ,  A61B2017/12072 ,  A61F2/01 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0076 ,  A61F2230/008 ,  A61F2230/0093

Abstract: Implant devices for filtering blood flowing through atrial appendage ostiums have elastic cover and anchoring substructures. The substructures may include reversibly folding tines or compressible wire braid structures. The devices are folded to fit in catheter tubes for delivery to the atrial appendages. The devices elastically expand to their natural sizes when they are expelled from the catheter tubes. Filter elements in the covers block emboli from escaping through the ostiums. The devices with tine substructures may have H-shaped cross sections. These devices seal the appendages by pinching an annular region of ostium tissue between the cover and the anchoring substructures. The shallow deployment depth of these H-shaped devices allows use of an universal device size for atrial appendages of varying lengths. The devices may include remotely activated fixtures for refolding the tines for device recovery or position adjustment.

Abstract translation: 用于过滤通过心耳附件的血液的植入装置具有弹性覆盖物和锚固子结构。 子结构可以包括可逆地折叠齿或可压缩的线编织结构。 这些装置被折叠以适合导管，用于递送到心房附件。 当装置从导管管排出时，这些装置弹性膨胀至其自然尺寸。 过滤元件在盖子阻塞栓塞从逃离通过口。 具有叉形结构的装置可具有H形横截面。 这些装置通过在盖和锚定子结构之间夹住口腔组织的环形区域来密封附件。 这些H型装置的浅部署深度允许使用通用装置尺寸用于不同长度的心房附件。 这些装置可以包括用于重新折叠齿的用于装置恢复或位置调整的远程激活的固定装置。

公开(公告)号：WO02017809A1

公开(公告)日：2002-03-07

申请号：PCT/US2000/023727

申请日：2000-08-29

IPC: A61B17/00 ,  A61B17/128 ,  A61B17/34 ,  A61B19/00

CPC classification number: A61B17/1285 ,  A61B17/00234 ,  A61B17/12013 ,  A61B2017/00243 ,  A61B2017/00247 ,  A61B2017/003 ,  A61B2017/00353 ,  A61B2017/00504 ,  A61B2017/00575 ,  A61B2017/00632 ,  A61B2017/3445 ,  A61B2018/00392

Abstract: Methods, and apparatus for closing a left atrial appendage are described. The methods rely on introducing a closure tool (10) from a location beneath the rib cage, over an epicardial surface, and to the exterior of the left atrial appendage. The closure device (200) may then be used to close the left atrial appendage, preferably at its base, by any one of a variety of techniques. A specific technique using grasper (10), and a closing loop (200) is illustrated.

Abstract translation: 描述了关闭左心耳的方法和装置。 该方法依赖于从肋骨下方的位置，心外膜表面和左心耳外部引入闭合工具（10）。 闭合装置（200）然后可用于通过各种技术中的任何一种来封闭左心耳，优选地在其基部。 示出了使用抓紧器（10）和闭合回路（200）的具体技术。

公开(公告)号：WO1995013762A1

公开(公告)日：1995-05-26

申请号：PCT/DK1994000434

申请日：1994-11-17

Applicant: EL-DOT KS ,  NIEBEN, Ole, Gyring

Inventor： EL-DOT KS

IPC: A61F02/02

CPC classification number: A61B17/12136 ,  A61B17/12099 ,  A61B90/02 ,  A61B2017/00606 ,  A61B2017/00632 ,  A61B2017/00641 ,  A61F2/0063 ,  A61F2002/0072

Abstract: Implantable support device to support a weakened region of a human or animal body wall and comprising at least two expandable balloons of a non-absorbable biocompatible material and being mutually connected by means of a tube or a pipe, wherein at least the one expandable balloon comprises a valve that permits inflow and prevents outflow of expansion agent and which is in communication with separable means for the supply of expansion agent.

Abstract translation: 可植入支撑装置，用于支撑人体或动物体壁的弱化区域，并且包括至少两个可吸收生物相容性材料的可膨胀气囊，并且通过管或管相互连接，其中至少一个可膨胀气囊包括 允许流入并防止膨胀剂流出并与用于供应膨胀剂的可分离装置连通的阀。