公开(公告)号：WO2010118056A1

公开(公告)日：2010-10-14

申请号：PCT/US2010/030131

申请日：2010-04-06

Applicant: SPIRATION, INC. ,  ADAMS, Martin, Neal ,  KUTSKO, James, Mark ,  O'CONNELL, Desmond

Inventor： ADAMS, Martin, Neal ,  KUTSKO, James, Mark ,  O'CONNELL, Desmond

IPC: A61F2/24 ,  A61F2/84

CPC classification number: A61F2/2436 ,  A61F2/0095 ,  A61F2/2412 ,  A61F2/966 ,  A61F2002/043 ,  A61F2002/9517 ,  A61F2002/9522 ,  A61F2250/008 ,  A61F2250/0097

Abstract: A medical device deployment catheter (702) with a distal portion with a locator marking (802,803) that permits accurate placement of the medical device. The locator marking may comprise a yellow pigmented band (803) with two black pigmented bands (802) disposed on either side of the yellow pigmented band. The catheter may further comprise a rigid tip (716) disposed at the distal end of the cavity inside the catheter shaft, the rigid tip able to accommodate at least a portion of the medical device loaded therein, wherein a at least partially transparent segment (801) disposed between the locator marking and the rigid tip, the at least partially transparent segment permitting visualization of at least a portion of the cavity near the distal end of the catheter shaft. The catheter shaft may further comprise a strain relief tube extending over at least a proximal portion of the catheter shaft.

Abstract translation: 一种具有远端部分的医疗装置展开导管（702），其具有允许医疗装置的精确放置的定位器标记（802,803）。 定位器标记可以包括黄色着色带（803），其具有设置在黄色着色带的任一侧上的两个黑色着色带（802）。 导管还可以包括设置在导管轴内的腔的远端处的刚性尖端（716），刚性尖端能够容纳加载在其中的医疗装置的至少一部分，其中至少部分透明的部分（801 ）设置在定位器标记和刚性尖端之间，所述至少部分透明的部分允许在导管轴的远端附近的空腔的至少一部分可视化。 导管轴还可以包括在导管轴的至少近端部分上延伸的应变消除管。

公开(公告)号：WO2006101958A3

公开(公告)日：2006-09-28

申请号：PCT/US2006/009481

申请日：2006-03-16

Applicant: SPIRATION, INC. ,  PEARCE, Joseph, R. ,  REDDY, David, J.

Inventor： PEARCE, Joseph, R. ,  REDDY, David, J.

IPC: A61B17/12

Abstract: The preferred embodiment of the invention contemplates a device configured to prepare and deploy a resilient sleeve on to a portion of body tissue. The device expands the resilient sleeve, uses a vacuum system to draw the body tissue in to the resilient sleeve, and releases the resilient sleeve from the expanded state so that it captures and constricts the body tissue.

公开(公告)号：WO2004032764A1

公开(公告)日：2004-04-22

申请号：PCT/US2003/031903

申请日：2003-10-09

Applicant: SPIRATION, INC.

Inventor： BARRY, Robert, Lawrence ,  FINGER, Clint

IPC: A61B17/08

CPC classification number: A61B17/08 ,  A61B17/083 ,  A61B2017/0406

Abstract: The invention provides an implantable tissue constriction device (70) and method for suppressing leakage from resectioned body tissue. The device includes a first elongated member (82) having a constricting surface (84), and a second elongated member (92) having another constricting surface (94), the constricting surfaces (84,94) being arranged in combination to circumscribe tissue to be excised, to an extent necessary to suppress leakage from body tissue remaining after excision of the tissue to be excised. One elongated constrictive surface may include a pliable material arranged to contact the circumscribed tissue and accommodate anatomical variations. The device (70) may include a pivot (72, 74) coupled between the first and second elongated members (82, 92), about which the constricting surfaces (84, 94) are moveable together in opposition. The devices may include a bias element (152) coupled between the first and second member that brings the constricting surfaces together in opposition.

Abstract translation: 本发明提供了一种可植入组织收缩装置（70）和用于抑制切除的人体组织的渗漏的方法。 所述装置包括具有收缩表面（84）的第一细长构件（82）和具有另一收缩表面（94）的第二细长构件（92），所述收缩表面（84,94）组合布置以将组织包围到 在必要的程度上切除，以抑制切除组织切除后剩余的身体组织的渗漏。 一个细长的收缩表面可以包括布置成接触外接组织并适应解剖变化的柔韧材料。 装置（70）可以包括联接在第一和第二细长构件（82,92）之间的枢轴（72,74），收缩表面（84,94）可围绕其枢转地相对移动。 这些装置可以包括耦合在第一和第二构件之间的偏压元件（152），其将收缩表面组合在一起。

公开(公告)号：WO2003094996A1

公开(公告)日：2003-11-20

申请号：PCT/US2003/014868

申请日：2003-05-09

Applicant: SPIRATION, INC.

Inventor： SIROKMAN, William, A.

IPC: A61M1/00

CPC classification number: A61M1/0013 ,  A61M1/0023

Abstract: A device according to an aspect of the invention includes an air escapement conduit (52) having an inlet port providing air communication with a chest cavity (51) and an outlet port providing air communicaiton with a vacuum source (22), the conduit allowing an air flow from the inlet port (48) to the outlet port (49) in response to a pressure differential between the ports, and a detector responsive to the air flow that provides a signal (S1) related to the air flow. The device may include an indicator device (60) operable to provide evacuation information in response to the signal. The air escapement conduit may include a bubble chamber (42) or a valving mechanism (210). The detector may be a pressure differential sensor (122) operable to detect a difference in air pressure between the inlet port and the outlet port, and generate a signal related (S1) to the difference.

Abstract translation: 根据本发明的一个方面的装置包括具有提供与胸腔（51）空气连通的入口端口和提供空气通道与真空源（22）的出口的空气逸出导管（52），所述导管允许 响应于端口之间的压力差，从入口端口（48）到出口端口（49）的空气流和响应于空气流的检测器，其提供与空气流相关的信号（S1）。 该装置可以包括可操作以响应于该信号提供疏散信息的指示器装置（60）。 空气逸出导管可以包括气泡室（42）或阀机构（210）。 检测器可以是可操作以检测入口和出口之间的空气压力差的压力差传感器（122），并且产生与差异相关的信号（S1）。

公开(公告)号：WO2003094863A3

公开(公告)日：2003-11-20

申请号：PCT/US2003/005887

申请日：2003-02-25

Applicant: SPIRATION, INC. ,  DILLARD, David, H. ,  ALFERNESS, Clifton, A. ,  DEVORE, Lauri, J. ,  GONZALES, Hugo, X.

Inventor： DILLARD, David, H. ,  ALFERNESS, Clifton, A. ,  DEVORE, Lauri, J. ,  GONZALES, Hugo, X.

IPC: A61M16/00

Abstract: An obstructive device (90) prevents air from being inhaled into a lung portion to collapse the lung portions while providing mucus transport from the lung portion. When placed in an air passageway serving the lung portion, the obstructing member (90) defines a pathway for mucus transport between the obstructing member (90) and the air passageway. The device (90) may include a tubular-shaped anchor to retain the device (90) in the air passageway. A pathway for mucus transport is provided between a portion of the anchor and a portion of the obstructing device (90).

公开(公告)号：WO2003088912A2

公开(公告)日：2003-10-30

申请号：PCT/US2003/011974

申请日：2003-04-16

Applicant: SPIRATION, INC. ,  DEVORE, Lauri, J.

Inventor： DEVORE, Lauri, J.

IPC: A61K

CPC classification number: A61F2/04 ,  A61B17/12022 ,  A61B17/12104 ,  A61B17/12159 ,  A61B17/12172 ,  A61B2017/1205 ,  A61B2017/22067 ,  A61B2017/242 ,  A61B2090/033 ,  A61F2/2412 ,  A61F2/2418 ,  A61F2002/043 ,  A61F2002/8483 ,  A61M16/0406

Abstract: An intra-bronchial device may be placed in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes an obstructing member that prevents air from being inhaled into the lung portion to collapse the lung portion, and an anchoring device that anchors the obstructing member in the air passageway by engaging the obstructing member and the air passageway wall. The anchoring device may frictionally engage the obstructing member and the air passageway, or engage both by piercing. The engagement provided by the anchoring device may be releasable for removal of the obstructing member. The anchoring device may be balloon expandable from a first shape to a second shape that engages the obstructing member and the air passageway. The obstructing member may be a one-way valve.

Abstract translation: 支气管内装置可以放置在患者的空气通道中以折叠与空气通道相关联的肺部分。 该装置包括防止空气被吸入肺部以塌缩肺部的阻塞构件，以及锚固装置，其通过接合阻塞构件和空气通道壁而将阻塞构件锚定在空气通道中。 锚固装置可以摩擦地接合阻塞构件和空气通道，或者通过穿刺两者接合。 由锚固装置提供的接合可以是可释放的，用于移除阻塞构件。 锚固装置可以是从第一形状到接合阻塞构件和空气通道的第二形状的球囊。 阻塞构件可以是单向阀。

公开(公告)号：WO2003088859A1

公开(公告)日：2003-10-30

申请号：PCT/US2003/005888

申请日：2003-02-25

Applicant: SPIRATION, INC. ,  BARRY, Robert, Lawrence

Inventor： BARRY, Robert, Lawrence

IPC: A61B18/18

CPC classification number: A61B18/1492 ,  A61B2017/003 ,  A61B2018/00541 ,  A61B2018/00589 ,  A61B2018/00601 ,  A61B2218/007

Abstract: A device, system, and method provides for removing deleterious tissue from healthy body tissue at a site inside a patient. The device includes a steerable electrosurgery device (88) having a electrode (98) to cut a core through tissue, including tissue surrounding a perimeter of the deleterious tissue, and a lumen (in 98) for aspirating the cored tissue from the patient. The electrode may form a closed loop, and may be the active electrode of an electrosurgery system. Further, the electrode may have a narrow profile. In addition, the electrode may be arranged to coagulate the cut tissue. The system includes the device and a seal to limit air leaks and bleeding from the removal of cored tissue.

Abstract translation: 装置，系统和方法提供从患者体内部位的健康身体组织去除有害组织。 该装置包括具有电极（98）的可操纵电外科装置（88），该电极（98）通过组织切割芯，包括围绕有害组织的周边的组织，以及用于从患者吸出芯组织的内腔（98）。 电极可以形成闭环，并且可以是电外科系统的活性电极。 此外，电极可以具有窄的轮廓。 此外，电极可以布置成使切割的组织凝结。 该系统包括装置和密封件，以限制漏气并从去除芯组织渗出。

公开(公告)号：WO2003079944A1

公开(公告)日：2003-10-02

申请号：PCT/US2003/005968

申请日：2003-02-26

Applicant: SPIRATION, INC. ,  ALFERNESS, Clifton, A. ,  DILLARD, David, H. ,  GONZALEZ, Hugo, X. ,  YI, Seung ,  DEVORE, Lauri, J. ,  PARK, Mia ,  CORCORAN, Dean, T. ,  RIMBAUGH, Jenni

Inventor： ALFERNESS, Clifton, A. ,  DILLARD, David, H. ,  GONZALEZ, Hugo, X. ,  YI, Seung ,  DEVORE, Lauri, J. ,  PARK, Mia ,  CORCORAN, Dean, T. ,  RIMBAUGH, Jenni

IPC: A61F11/00

CPC classification number: A61B17/12022 ,  A61B17/12104 ,  A61B17/12131 ,  A61B17/12159 ,  A61B17/12172 ,  A61B2017/1205 ,  A61B2017/22051 ,  A61B2017/22067 ,  A61F2002/043

Abstract: An intra-bronchial device (100) may be placed and anchored in an air passageway (50) of a patient to collapse a lung portion associated with the air passageway. The device includes an obstructing member (110) that prevents air from being inhaled into the lung portion, and an anchor (112) that anchors the obstruction device (110) within the air passageway. The anchor (112) may piercingly engage the air passageway wall. The anchor (112) may be releasable from the air passageway wall. The anchor (112) may be releasable from the air passageway for removal of the obstructing member (110). The anchor (112) may be releasable by collapsing a portion of the obstructing member (110), or by drawing the obstructing member toward the larynx. The obstructing member (110) may be a one-way valve.

Abstract translation: 可以将支气管内装置（100）放置并锚定在患者的空气通道（50）中以折叠与空气通道相关联的肺部分。 该装置包括防止空气被吸入肺部的阻塞构件（110），以及将阻塞装置（110）锚定在空气通道内的锚固件（112）。 锚（112）可以穿透地接合空气通道壁。 锚（112）可以从空气通道壁释放。 锚固件（112）可以从空气通道释放以去除阻塞构件（110）。 锚固件（112）可以通过塌缩阻塞构件（110）的一部分，或者通过将阻塞构件拉向喉部来释放。 阻塞构件（110）可以是单向阀。

公开(公告)号：WO2003005884A2

公开(公告)日：2003-01-23

申请号：PCT/US2002/021688

申请日：2002-07-09

Applicant: SPIRATION, INC. ,  ALFERNESS, Clifton, A. ,  BARRY, Robert ,  FINGER, Clint ,  SNYDER, Leslie ,  RIMBAUGH, Jenni

Inventor： ALFERNESS, Clifton, A. ,  BARRY, Robert ,  FINGER, Clint ,  SNYDER, Leslie ,  RIMBAUGH, Jenni

IPC: A61B

CPC classification number: A61B17/00234 ,  A61B17/12013 ,  A61B2017/1142 ,  A61B2017/306 ,  A61F2/0063 ,  A61F2/04 ,  A61F2002/043

Abstract: A constriction device that constricts body tissue includes fixation structures for fixing the device on constricted body tissue. The device includes an elongated sleeve including an inner surface and opposed opened ends. The device is formed from expandable or elastic material so that when in an expanded condition, body tissue to be constricted may be received therein and thereafter, when released from the expanded condition, the body tissue is constricted by the device. The fixation structures include a plurality of fixation elements on the inner surface of the sleeve that grasp the body tissue upon release of the sleeve from the expanded condition to fix the device on the constricted tissue.

Abstract translation: 收缩身体组织的收缩装置包括用于将装置固定在收缩的身体组织上的固定结构。 该装置包括细长的套筒，其包括内表面和相对的开口端。 该装置由可膨胀或弹性材料形成，使得当处于膨胀状态时，待收缩的身体组织可以被容纳在其中，此后，当从扩张状态释放时，身体组织被装置收缩。 固定结构包括在套筒内表面上的多个固定元件，当将套筒从膨胀状态释放时抓住身体组织，以将该装置固定在收缩的组织上。

公开(公告)号：WO2020033950A1

公开(公告)日：2020-02-13

申请号：PCT/US2019/046161

申请日：2019-08-12

Applicant: SPIRATION, INC D/B/A OLYMPUS RESPIRATORY AMERICA

Inventor： NELSON, Jeffrey, J. ,  BATCHELOR, Kester, J. ,  MURDESHWAR, Nikhil, M. ,  BOONE, Eric, J. ,  FIKSEN, Christian, J.

IPC: A61B18/14 ,  A61B18/00 ,  A61B18/12

Abstract: A device comprising: a first jaw having a gripping surface; a second jaw having a gripping surface, the second jaw being spaced apart from the first jaw and being configured to move between an open position and a closed position, and a sealer divider having a plurality of stops including at least: one or more distal stops, one or more proximal stops; and one or more intermediate stops that are of an intermediate height when compared to a height of the one or more distal stops and a height the one or more proximal stops, and wherein the plurality of stops are non-conductive and are distributed on the gripping surface of the first jaw, the gripping surface of the second jaw, or both, and wherein the first jaw and the second jaw have a proximal end and a distal end and the plurality of stops produce a gap that is widest at the proximal end and tapers so that a gap at the distal end is narrower than the gap at the proximal end.