Abstract:
Novel compounds and compositions that can be used to bind tubulin, prevent tubulin polymerization, inhibit cell growth, arrest cell cyle, cause cell death, or treat cancer or abnormal cell proliferation disorders. Also disclosed are methods for identifying, synthesizing, and using such compounds.
Abstract:
A decontaminant composition comprising a peroxide; an organic co-solvent; an amine, which in reaction with the peroxide is a source of a perhydrolysis species; a phase transfer catalyst comprising at least one quaternary ammonium compound; a metal oxide catalyst; a chemical base; and at least one pH buffering compound.
Abstract:
A microbicidal and decontaminant composition comprising an aqueous solution of peroxides and peracids having equilibrium reaction products, a photoreactive surfactant, and a polymer, wherein said polymer interacts with said peroxides and said peracids.
Abstract:
The invention relates to a polymerisation process wherein at least one initiator is selected from trioxepan compounds of formula I, with R being independently selected from substituted or unsubstituted hydrocarbyl groups. Preferably, R and R are selected from lower alkyl groups, such as methyl, ethyl, and isopropyl, while R is preferably selected from methyl, ethyl, isopropyl, isobutyl, amyl, isoamyl, cyclohexyl, CH3C(O)CH2-, C2H5OC(O)CH2-, HOC(CH3)2CH2-, and [...].
Abstract:
The invention relates to a method for producing a peroxyacetic acid or peroxypropionic acid solution by reacting acetic acid or propionic acid with hydrogen peroxide in the presence of a polyphosphoric acid catalyst. The catalyst used in the inventive method is a water-free solution that is obtained by dissolving 0.1 to 99 % by weight, especially 1 to 35 % by weight (based on the solution) of a polyphosphoric acid in the carboxylic acid that is to be converted to the peroxycarboxylic acid. The catalyst solution is preferably produced using molten polyphosphoric acid on the site of production of the same.
Abstract:
A process for producing hydroperoxides by oxidizing a hydrocarbon with an oxygen-containing gas in the presence of a specified compound to selectively convert the hydrocarbon into a corresponding hydroperoxide. The specified compounds are those capable of trapping free radicals, and preferred examples thereof include oxygen, nitrogen, phosphorus, sulfur, carbon and silicon radicals, and compounds capable of forming such radicals in a reaction system. This process is applicable to the oxidation of hydrocarbons including arylalkylhydrocarbons such as cumene, cymene, m-diisopropylbenzene, p-diisopropylbenzene, 1,3,5-triisopropylbenzene, isopropylnaphthalene, diisopropylnaphthalene, isopropylbiphenyl and diisopropylbiphenyl.
Abstract:
A method of stabilizing nitriles, and in particular iminodiacetonitrile (IDAN), ethylendiamine-triacetonitrile (EDTN), and especially nitrilotriacetonitrile (NTAN). The present invention also encompasses the resulting stabilized nitrile. The method of the present invention comprises contacting the nitrile with a mixture of silica and alumina, zeolites or glass.
Abstract:
Process for the production composite articles, comprising the steps of: a)providing a curable mixture comprising: -30-95 wt% of filler material, -5-70 wt% of resin, selected from unsaturated polyester resins, vinyl ester resins, (meth)acrylate resins, and combinations thereof, -0.5-10 phr of at least one peroxyester, -0.1-2.0phr of at least one organic hydroperoxide, the weight ratio peroxyester/organic hydroperoxide being below 14.0, the curablemixture being essentially free of ketone peroxide, b)shaping the mixture, and c)heating the shaped mixture at a temperature in the range 60-100°C to affect hardening of the resin and the formation of an article.
Abstract:
Evaporation of water from an aqueous dispersion of a solid peroxide such as benzoyl peroxide is retarded by the incorporation of carboxylic acid salt. The carboxylic acid salt renders the aqueous dispersion less susceptible to explosive decomposition when exposed to external triggering events such as impact, heat, friction or contamination, yet does not interfere with the ability to achieve and maintain a stable, small particle size dispersion having desirable viscosity and flow properties.
Abstract:
Methods for preparing esters by ozonolysis of cycloolefins are provided wherein, for example, an intermediate of formula IIa: is transformed to a compound of formula III:, wherein A is a C6-C10alkene chain with at least one double bond, R1 is a C1-C10alkyl, and R3 is an oxygen-containing functional group.